iofetamine has been researched along with Machado-Joseph Disease in 2 studies
Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
Machado-Joseph Disease: A dominantly-inherited ATAXIA first described in people of Azorean and Portuguese descent, and subsequently identified in Brazil, Japan, China, and Australia. This disorder is classified as one of the SPINOCEREBELLAR ATAXIAS (Type 3) and has been associated with a mutation of the MJD1 gene on chromosome 14. Clinical features include progressive ataxia, DYSARTHRIA, postural instability, nystagmus, eyelid retraction, and facial FASCICULATIONS. DYSTONIA is prominent in younger patients (referred to as Type I Machado-Joseph Disease). Type II features ataxia and ocular signs; Type III features MUSCULAR ATROPHY and a sensorimotor neuropathy; and Type IV features extrapyramidal signs combined with a sensorimotor neuropathy. (From Clin Neurosci 1995;3(1):17-22; Ann Neurol 1998 Mar;43(3):288-96)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Machado-Joseph disease (MJD) is an autosomal dominant spinocerebellar ataxia." | 1.31 | [Analysis of regional cerebral blood flow and distribution volume in Machado-Joseph disease by iodine-123I IMP single photon emission computed tomography]. ( Fukuhara, N; Hayashi, T; Nakajima, T, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takahashi, N | 1 |
| Odano, I | 1 |
| Nishihara, M | 1 |
| Yuasa, T | 1 |
| Sakai, K | 1 |
| Hayashi, T | 1 |
| Nakajima, T | 1 |
| Fukuhara, N | 1 |
1 trial available for iofetamine and Machado-Joseph Disease
| Article | Year |
|---|---|
Regional cerebral blood flow measured with N-isopropyl-p-[123I]iodoamphetamine single-photon emission tomography in patients with Joseph disease.
Topics: Adult; Amphetamines; Brain; Cerebrovascular Circulation; Female; Humans; Iodine Radioisotopes; Iofet | 1994 |
1 other study available for iofetamine and Machado-Joseph Disease
| Article | Year |
|---|---|
[Analysis of regional cerebral blood flow and distribution volume in Machado-Joseph disease by iodine-123I IMP single photon emission computed tomography].
Topics: Aged; Brain; Female; Humans; Iodine Radioisotopes; Iofetamine; Machado-Joseph Disease; Male; Middle | 2001 |