iofetamine has been researched along with MELAS Syndrome in 5 studies
Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "All patients with MELAS showed focal hypoperfusion in the parietal and/or occipital lobes." | 1.30 | SPECT findings in mitochondrial encephalomyopathy. ( Hashikawa, K; Kodaka, R; Kusuoka, H; Moriwaki, H; Nishimura, T; Oku, N; Ono, J; Seike, Y; Uehara, T; Watanabe, Y, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sudo, A | 1 |
| Sasaki, M | 1 |
| Sugai, K | 1 |
| Matsuda, H | 1 |
| Suzuki, Y | 1 |
| Tsukuda, K | 1 |
| Atsumi, Y | 1 |
| Goto, Y | 1 |
| Hosokawa, K | 1 |
| Asahina, T | 1 |
| Nonaka, I | 1 |
| Matsuoka, K | 1 |
| Oka, Y | 1 |
| Miyamoto, A | 1 |
| Oki, J | 1 |
| Takahashi, S | 1 |
| Itoh, J | 1 |
| Kusunoki, Y | 1 |
| Cho, K | 1 |
| Ohkubo, M | 1 |
| Odano, I | 1 |
| Noguchi, E | 1 |
| Ohtaki, H | 1 |
| Shibaki, M | 1 |
| Dobashi, Y | 1 |
| Yokoi, T | 1 |
| Watanabe, Y | 1 |
| Hashikawa, K | 1 |
| Moriwaki, H | 1 |
| Oku, N | 1 |
| Seike, Y | 1 |
| Kodaka, R | 1 |
| Ono, J | 1 |
| Uehara, T | 1 |
| Kusuoka, H | 1 |
| Nishimura, T | 1 |
5 other studies available for iofetamine and MELAS Syndrome
| Article | Year |
|---|---|
Therapeutic effect and [123I]IMP SPECT findings of sodium dichloroacetate in a patient with MELAS.
Topics: Adolescent; Dichloroacetic Acid; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Iofetamine; Lac | 2004 |
Clinical picture of a case of diabetes with mitochondrial tRNA mutation at position 3271.
Topics: Adult; Amphetamines; Brain; Diabetes Mellitus; Female; Genomic Imprinting; Hair; Humans; Iodine Radi | 1996 |
Serial imaging in MELAS.
Topics: Amphetamines; Brain; Child; Energy Metabolism; Fatal Outcome; Female; Humans; Iodine Radioisotopes; | 1997 |
[A study on accuracy of rCBF measurements loaded with acetazolamide based on the microsphere model using iodine-123-IMP SPECT].
Topics: Acetazolamide; Adult; Amphetamines; Brain; Cerebral Infarction; Cerebrovascular Circulation; Female; | 1998 |
SPECT findings in mitochondrial encephalomyopathy.
Topics: Adolescent; Adult; Amphetamines; Brain; Cerebrovascular Circulation; Child; Female; Humans; Iodine R | 1998 |