iofetamine has been researched along with Ischemic Attack, Transient in 12 studies
Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 7.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 3.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "She suffered temporary left facial palsy 5 days after surgery." | 1.34 | Symptomatic hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in a child with moyamoya disease. ( Fujimura, M; Kaneta, T; Shimizu, H; Tominaga, T, 2007) |
| "In three patients studied during seizure activity, regions of hyperperfusion corresponded to the EEG seizure focus." | 1.26 | Initial experience with SPECT (single-photon computerized tomography) of the brain using N-isopropyl I-123 p-iodoamphetamine: concise communication. ( Baldwin, RM; Clouse, ME; Front, D; Hill, TC; Holman, BL; Lin, TH; Lovett, R; Magistretti, P; Moore, S; O'Leary, DH; Wu, JL; Zimmerman, RE, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (50.00) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujimura, M | 1 |
| Kaneta, T | 1 |
| Shimizu, H | 1 |
| Tominaga, T | 1 |
| Hill, TC | 1 |
| Holman, BL | 1 |
| Lovett, R | 1 |
| O'Leary, DH | 1 |
| Front, D | 1 |
| Magistretti, P | 1 |
| Zimmerman, RE | 1 |
| Moore, S | 1 |
| Clouse, ME | 1 |
| Wu, JL | 1 |
| Lin, TH | 1 |
| Baldwin, RM | 1 |
| Kimura, T | 1 |
| Shinoda, J | 1 |
| Funakoshi, T | 1 |
| Hirano, A | 1 |
| Hashimoto, T | 1 |
| Kobayashi, Y | 1 |
| Sohma, F | 1 |
| Fujiwara, H | 1 |
| Hashi, K | 1 |
| Watanabe, Y | 1 |
| Nakano, T | 1 |
| Yutani, K | 1 |
| Nishimura, H | 1 |
| Kusuoka, H | 1 |
| Nakamura, H | 1 |
| Nishimura, T | 2 |
| Tsuda, Y | 1 |
| Ayada, Y | 1 |
| Takahashi, T | 1 |
| Katsuragawa, M | 1 |
| Tanabe, M | 1 |
| Toyama, Y | 1 |
| Matsuo, H | 1 |
| Hayashida, K | 1 |
| Imakita, S | 1 |
| Uehara, T | 1 |
| Grünwald, F | 1 |
| Broich, K | 1 |
| Kropp, J | 1 |
| Hartmann, A | 1 |
| Biersack, HJ | 1 |
| Cesaro, P | 2 |
| Moretti, JL | 2 |
| Caron, JP | 1 |
| Roualdes, B | 1 |
| Louarn, F | 1 |
| N'guyen, JP | 1 |
| Gaston, A | 1 |
| Degos, JD | 2 |
| König, B | 1 |
| Donis, J | 1 |
| Mostbeck, A | 1 |
| Köhn, H | 1 |
| Defer, G | 1 |
| Sergent, A | 1 |
| Raynaud, C | 1 |
| Tobita, M | 1 |
| Nagasawa, H | 1 |
| Kogure, K | 1 |
| Sato, H | 1 |
| Yoshioka, S | 1 |
| Matsuzawa, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| C-arm Cone Beam CTA and CTP With Acetazolamide Challenge in Aneurysmal Subarachnoid Hemorrhage: Evaluating Predictability for Early Ischemia in Cerebral Vasospasm[NCT03377049] | Phase 4 | 11 participants (Actual) | Interventional | 2019-07-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes. (NCT03377049)
Timeframe: Day 1-14 during the hospitalization
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetazolamide Challenge | 2 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 19.785 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 21.659 |
The data that will be statistically compared is the pre-diamox perfusion in comparison to the post-diamox perfusion. A statistically significant change increase in CBF represents an appropriate response to Diamox. Lack of change in CBF or decrease in CBF could be suggestive of potential for developing vasospasm. (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 20.722 |
12 other studies available for iofetamine and Ischemic Attack, Transient
| Article | Year |
|---|---|
Symptomatic hyperperfusion after superficial temporal artery-middle cerebral artery anastomosis in a child with moyamoya disease.
Topics: Anastomosis, Surgical; Cerebral Angiography; Cerebral Revascularization; Cerebrovascular Circulation | 2007 |
Initial experience with SPECT (single-photon computerized tomography) of the brain using N-isopropyl I-123 p-iodoamphetamine: concise communication.
Topics: Amphetamines; Brain; Brain Neoplasms; Cerebrovascular Circulation; Cerebrovascular Disorders; Humans | 1982 |
Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amphetamines; Aneurysm, Ruptured; Brain; Cerebral Inf | 1993 |
[Two cases of delayed posttraumatic vasospasm followed by brain SPECT].
Topics: Aged; Amphetamines; Brain; Brain Concussion; Brain Injuries; Female; Humans; Iodine Radioisotopes; I | 1997 |
Detection of viable cortical neurons using benzodiazepine receptor imaging after reversible focal ischaemia in rats: comparison with regional cerebral blood flow.
Topics: Animals; Autoradiography; Brain; Brain Chemistry; Cerebrovascular Circulation; Flumazenil; Iodine Ra | 2000 |
Semiquantitative regional cerebral blood flow evaluation using 123I-IMP SPECT in a case showing transient ischemic attack caused by putaminal hemorrhage.
Topics: Aged; Amphetamines; Basal Ganglia; Cerebral Cortex; Cerebral Hemorrhage; Female; Humans; Iodine Radi | 1991 |
Does the washout phenomenon of Tc-99m HM-PAO correlate to the "filling-in" phenomenon of I-123 IMP with brain SPECT?
Topics: Aged; Amphetamines; Brain; Cerebral Infarction; Cerebrovascular Circulation; Female; Humans; Iodine | 1990 |
[SPECT in reversible symptoms of cerebrovascular diseases].
Topics: Adult; Aged; Amphetamines; Brain Ischemia; Cerebrovascular Disorders; Female; Humans; Iodine Radiois | 1989 |
[Cerebral tomoscintigraphy with N-isopropyl-p-I123-iodoamphetamine. Value in cerebral ischemic pathology].
Topics: Amphetamines; Arterial Occlusive Diseases; Brain Ischemia; Cerebellar Diseases; Cerebral Arterial Di | 1985 |
[Single-photon emission tomography (SPECT) using 123I-amphetamine in cerebral ischemic circulatory disorders].
Topics: Amphetamines; Brain Ischemia; Carotid Arteries; Cerebral Infarction; Endarterectomy; Female; Humans; | 1987 |
Early and delayed SPECT using N-isopropyl p-iodoamphetamine iodine 123 in cerebral ischemia. A prognostic index for clinical recovery.
Topics: Adult; Aged; Amphetamines; Brain; Brain Ischemia; Female; Humans; Iodine Radioisotopes; Iofetamine; | 1987 |
Sequential cerebral blood flow study by chrono-autoradiography.
Topics: Amphetamines; Animals; Antipyrine; Autoradiography; Cerebrovascular Circulation; Iofetamine; Ischemi | 1986 |