iofetamine has been researched along with Intracranial Aneurysm in 8 studies
Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 7.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "Prediction of cerebral infarction due to vasospasm (VS) following aneurysmal subarachnoid haemorrhage (SAH) was investigated using acetazolamide-activated (A-A) N-isopropyl-p-[123I]iodoamphetamine (123I-IMP) single photon emission computed tomography (SPECT) in 79 SAH patients." | 3.68 | Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT. ( Funakoshi, T; Kimura, T; Shinoda, J, 1993) |
| "Chronic hydrocephalus after aneurysmal sub-arachnoid haemorrhage (SAH) is easily diagnosed in most cases." | 2.69 | Role of 123I-IMP SPET in the early diagnosis of borderline chronic hydrocephalus after aneurysmal subarachnoid haemorrhage. ( Kondoh, I; Ohkuma, H; Suzuki, S; Tanaka, M, 2000) |
| "Postoperative amnesia after surgery for anterior communicating artery aneurysm might be associated with the damage of the basal forebrain." | 1.56 | Relationship between decreased cerebral blood flow and amnesia after microsurgery for anterior communicating artery aneurysm. ( Kikuchi, H; Mori, E; Mori, N; Mugikura, S; Takahashi, S; Takase, K, 2020) |
| "After recovery from symptomatic cerebral vasospasm, the patient became restless and suffered from right hemiparesis on post-SAH day 12." | 1.56 | Symptomatic Cerebral Hyperperfusion After Cerebral Vasospasm Associated with Aneurysmal Subarachnoid Hemorrhage. ( Endo, H; Fujimura, M; Niizuma, K; Sakata, H; Tominaga, T, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mugikura, S | 1 |
| Mori, N | 1 |
| Kikuchi, H | 1 |
| Mori, E | 1 |
| Takahashi, S | 1 |
| Takase, K | 1 |
| Sakata, H | 1 |
| Endo, H | 1 |
| Fujimura, M | 1 |
| Niizuma, K | 1 |
| Tominaga, T | 1 |
| Ohkuma, H | 2 |
| Suzuki, S | 2 |
| Kudo, K | 1 |
| Islam, S | 1 |
| Kikkawa, T | 1 |
| Walker, BS | 1 |
| Mathews, D | 1 |
| Batjer, H | 1 |
| Allen, BC | 1 |
| Purdy, PD | 1 |
| Kimura, T | 1 |
| Shinoda, J | 1 |
| Funakoshi, T | 1 |
| Tanaka, M | 1 |
| Kondoh, I | 1 |
| Kamiya, K | 1 |
| Yamashita, N | 1 |
| Nagai, H | 1 |
| Mizawa, I | 1 |
| Ueda, T | 1 |
| Kinoshita, K | 1 |
| Watanabe, K | 1 |
| Hoshi, H | 1 |
| Jinnouchi, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| C-arm Cone Beam CTA and CTP With Acetazolamide Challenge in Aneurysmal Subarachnoid Hemorrhage: Evaluating Predictability for Early Ischemia in Cerebral Vasospasm[NCT03377049] | Phase 4 | 11 participants (Actual) | Interventional | 2019-07-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinical neurological deterioration not attributable to other causes, mores specifically not due to re-bleeding, hydrocephalus, or metabolic changes. (NCT03377049)
Timeframe: Day 1-14 during the hospitalization
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetazolamide Challenge | 2 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 19.785 |
Using perfusion map values, relative percent change will be calculated (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 21.659 |
The data that will be statistically compared is the pre-diamox perfusion in comparison to the post-diamox perfusion. A statistically significant change increase in CBF represents an appropriate response to Diamox. Lack of change in CBF or decrease in CBF could be suggestive of potential for developing vasospasm. (NCT03377049)
Timeframe: pre and post perfusion during imaging procedure, up to an hour
| Intervention | percent change (Mean) |
|---|---|
| Acetazolamide Challenge | 20.722 |
1 trial available for iofetamine and Intracranial Aneurysm
| Article | Year |
|---|---|
Role of 123I-IMP SPET in the early diagnosis of borderline chronic hydrocephalus after aneurysmal subarachnoid haemorrhage.
Topics: Aged; Cerebral Ventricles; Cerebrovascular Circulation; Female; Humans; Hydrocephalus; Intracranial | 2000 |
7 other studies available for iofetamine and Intracranial Aneurysm
| Article | Year |
|---|---|
Relationship between decreased cerebral blood flow and amnesia after microsurgery for anterior communicating artery aneurysm.
Topics: Adult; Aged; Amnesia; Basal Forebrain; Brain Mapping; Cerebrovascular Circulation; Female; Gyrus Cin | 2020 |
Symptomatic Cerebral Hyperperfusion After Cerebral Vasospasm Associated with Aneurysmal Subarachnoid Hemorrhage.
Topics: Aged; Aneurysm, Ruptured; Antihypertensive Agents; Cerebral Angiography; Cerebrovascular Circulation | 2020 |
Cortical blood flow during cerebral vasospasm after aneurysmal subarachnoid hemorrhage: three-dimensional N-isopropyl-p-[(123)I]iodoamphetamine single photon emission CT findings.
Topics: Adult; Aged; Angiography, Digital Subtraction; Blood Flow Velocity; Blood Volume; Brain Ischemia; Ce | 2003 |
Detection of cerebral hypoperfusion during trial carotid occlusion with reversal following extracranial-intracranial bypass prior to permanent occlusion.
Topics: Aged; Amphetamines; Brain; Carotid Artery Diseases; Carotid Artery, Internal; Catheterization; Cereb | 1994 |
Prediction of cerebral infarction due to vasospasm following aneurysmal subarachnoid haemorrhage using acetazolamide-activated 123I-IMP SPECT.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amphetamines; Aneurysm, Ruptured; Brain; Cerebral Inf | 1993 |
Investigation of normal pressure hydrocephalus by 123I-IMP SPECT.
Topics: Aged; Amphetamines; Brain Diseases; Cerebrospinal Fluid Shunts; Cerebrovascular Circulation; Frontal | 1991 |
[Local cerebral blood flow measurement using 123I-IMP SPECT in patients with cerebrovascular diseases].
Topics: Adult; Amphetamines; Brain; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; | 1987 |