Page last updated: 2024-10-29

iofetamine and Huntington Disease

iofetamine has been researched along with Huntington Disease in 2 studies

Iofetamine: An amphetamine analog that is rapidly taken up by the lungs and from there redistributed primarily to the brain and liver. It is used in brain radionuclide scanning with I-123.

Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)

Research Excerpts

ExcerptRelevanceReference
" Treatment with memantine prevented the chorea movement and the progression of Huntington's disease."8.31Memantine administration prevented chorea movement in Huntington's disease: a case report. ( Hirano, M; Ikegawa, A; Kusunoki, S; Mitsui, Y; Nagai, Y; Oda, I; Saigoh, K; Samukawa, M; Yamagishi, Y; Yoshikawa, K, 2023)
" Treatment with memantine prevented the chorea movement and the progression of Huntington's disease."4.31Memantine administration prevented chorea movement in Huntington's disease: a case report. ( Hirano, M; Ikegawa, A; Kusunoki, S; Mitsui, Y; Nagai, Y; Oda, I; Saigoh, K; Samukawa, M; Yamagishi, Y; Yoshikawa, K, 2023)
"For six patients with Huntington's disease, the average caudate ratio was 29."1.27Decreased iodine-123 IMP caudate nucleus uptake in patients with Huntington's disease. ( English, RJ; Holman, BL; Ichise, M; Johnson, KA; Morris, JH; Nagel, JS; Walshe, TM, 1988)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Saigoh, K1
Hirano, M1
Mitsui, Y1
Oda, I1
Ikegawa, A1
Samukawa, M1
Yoshikawa, K1
Yamagishi, Y1
Kusunoki, S1
Nagai, Y1
Nagel, JS1
Johnson, KA1
Ichise, M1
English, RJ1
Walshe, TM1
Morris, JH1
Holman, BL1

Other Studies

2 other studies available for iofetamine and Huntington Disease

ArticleYear
Memantine administration prevented chorea movement in Huntington's disease: a case report.
    Journal of medical case reports, 2023, Oct-16, Volume: 17, Issue:1

    Topics: Aged; Alzheimer Disease; Chorea; Dyskinesias; Female; Humans; Huntington Disease; Iofetamine; Male;

2023
Decreased iodine-123 IMP caudate nucleus uptake in patients with Huntington's disease.
    Clinical nuclear medicine, 1988, Volume: 13, Issue:7

    Topics: Amphetamines; Caudate Nucleus; Female; Humans; Huntington Disease; Iodine Radioisotopes; Iofetamine;

1988