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iodoacetic acid and Retinal Degeneration

iodoacetic acid has been researched along with Retinal Degeneration in 14 studies

Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.
iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.

Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)

Research Excerpts

ExcerptRelevanceReference
"We investigated structural changes in the retina by using optical coherence tomography (OCT) in a feline model of retinal degeneration using iodoacetic acid (IAA)."7.91Analysis of Changes in Retinal Photoreceptors Using Optical Coherence Tomography in a Feline Model of Iodoacetic Acid-induced Retinal Degeneration. ( Lee, MS; Lee, SJ; Lee, SU; Lim, JW; Noh, GM, 2019)
"Animal models with pharmacologically induced retinal degeneration including sodium iodate (NaIO3) and N-methyl-N-nitrosourea (MNU) have been extensively used in ophthalmic research to investigate retinal degeneration."4.95What Can Pharmacological Models of Retinal Degeneration Tell Us? ( Balmer, JM; Enzmann, V; Reisenhofer, MH, 2017)
"We investigated structural changes in the retina by using optical coherence tomography (OCT) in a feline model of retinal degeneration using iodoacetic acid (IAA)."3.91Analysis of Changes in Retinal Photoreceptors Using Optical Coherence Tomography in a Feline Model of Iodoacetic Acid-induced Retinal Degeneration. ( Lee, MS; Lee, SJ; Lee, SU; Lim, JW; Noh, GM, 2019)
"Iodoacetic acid (IAA) has been applied to different species to acutely induce photoreceptor degeneration."1.39Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat. ( Gao, J; Huang, X; Li, X; Nan, Y; Pu, M; Ren, C; Zhang, Q, 2013)
"Outer retinal degenerations were induced by injecting intravenously either monoiodoacetic acid (IAA) or sodium iodate (NaIO3)."1.29Can potentials from the visual cortex be elicited electrically despite severe retinal degeneration and a markedly reduced electroretinogram? ( de Juan, E; Humayun, M; Propst, R; Sato, Y, 1995)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's9 (64.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Noh, GM1
Lim, JW1
Lee, MS1
Lee, SU1
Lee, SJ1
Barone, F2
Muscatello, LV1
Ventrella, D2
Elmi, A2
Romagnoli, N1
Mandrioli, L1
Maya-Vetencourt, JF1
Bombardi, C1
Mete, M1
Sarli, G1
Benfenati, F2
Pertile, G2
Bacci, ML2
Reisenhofer, MH1
Balmer, JM1
Enzmann, V1
Laghi, L1
Carnevali, G1
Zhu, C1
Nan, Y1
Zhang, Q1
Ren, C1
Huang, X1
Gao, J1
Li, X1
Pu, M1
Rösch, S1
Johnen, S1
Mazinani, B1
Müller, F1
Pfarrer, C1
Walter, P1
Yamauchi, Y1
Agawa, T1
Tsukahara, R1
Kimura, K1
Yamakawa, N1
Miura, M1
Goto, H1
Scott, PA2
Kaplan, HJ3
Sandell, JH2
Wang, W2
Fernandez de Castro, J1
Vukmanic, E1
Zhou, L1
Emery, D1
Demarco, PJ2
Dean, DC1
Noel, JM1
Fernandez de Castro, JP1
Franco, LM1
Vukmanic, EV1
Peng, X1
McCall, MA1
Magomedov, NM1
Neĭman-zade, NK1
Kulieva, EM1
Dzhafarov, AI1
Akhmedli, GT1
Farber, DB1
Souza, DW1
Chase, DG1
Humayun, M1
Sato, Y1
Propst, R1
de Juan, E1
Gasanov, GG1
Gadzhieva, NA1
Rzaeva, NM1
Dmitrenko, AI1
Kulieva, FB1

Reviews

1 review available for iodoacetic acid and Retinal Degeneration

ArticleYear
What Can Pharmacological Models of Retinal Degeneration Tell Us?
    Current molecular medicine, 2017, Volume: 17, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Drug-Related Side Effects and Adverse Reacti

2017

Other Studies

13 other studies available for iodoacetic acid and Retinal Degeneration

ArticleYear
Analysis of Changes in Retinal Photoreceptors Using Optical Coherence Tomography in a Feline Model of Iodoacetic Acid-induced Retinal Degeneration.
    Korean journal of ophthalmology : KJO, 2019, Volume: 33, Issue:6

    Topics: Animals; Axial Length, Eye; Blood Glucose; Body Weight; Cats; Disease Models, Animal; Enzyme Inhibit

2019
The porcine iodoacetic acid model of retinal degeneration: Morpho-functional characterization of the visual system.
    Experimental eye research, 2020, Volume: 193

    Topics: Animals; Disease Models, Animal; Electroretinography; Enzyme Inhibitors; Female; Iodoacetic Acid; Ma

2020
1H NMR Spectroscopy Characterization of Porcine Vitreous Humor in Physiological and Photoreceptor Degeneration Conditions.
    Investigative ophthalmology & visual science, 2019, 02-01, Volume: 60, Issue:2

    Topics: Amino Acids; Animals; Eye Diseases; Female; Iodoacetic Acid; Male; Metabolome; Metabolomics; Models,

2019
Functional evaluation of iodoacetic acid induced photoreceptor degeneration in the cat.
    Science China. Life sciences, 2013, Volume: 56, Issue:6

    Topics: Animals; Blindness; Cats; Disease Models, Animal; Electroretinography; Female; Injections, Intraveno

2013
The effects of iodoacetic acid on the mouse retina.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2015, Volume: 253, Issue:1

    Topics: Animals; Cataract; Electroretinography; Enzyme Inhibitors; Female; Injections, Intravenous; Intravit

2015
Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an iodoacetic acid-induced model of retinal degeneration in rabbits.
    The British journal of ophthalmology, 2011, Volume: 95, Issue:8

    Topics: Animals; Disease Models, Animal; Enzyme Inhibitors; Iodoacetic Acid; Photoreceptor Cells, Vertebrate

2011
Anatomical evidence of photoreceptor degeneration induced by iodoacetic acid in the porcine eye.
    Experimental eye research, 2011, Volume: 93, Issue:4

    Topics: Animals; Biomarkers; Calbindins; Cell Count; Disease Models, Animal; Dose-Response Relationship, Dru

2011
Selective rod degeneration and partial cone inactivation characterize an iodoacetic acid model of Swine retinal degeneration.
    Investigative ophthalmology & visual science, 2011, Oct-07, Volume: 52, Issue:11

    Topics: Animals; Cell Count; Cell Survival; Chromosome Pairing; Disease Models, Animal; Dose-Response Relati

2011
Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage.
    Experimental eye research, 2012, Volume: 97, Issue:1

    Topics: Animals; Blood Glucose; Dark Adaptation; Disease Models, Animal; Dose-Response Relationship, Drug; E

2012
[Study of lipid peroxidation in experimental retinal degeneration].
    Biulleten' eksperimental'noi biologii i meditsiny, 1983, Volume: 95, Issue:3

    Topics: Animals; Ascorbic Acid; Electroretinography; Ferrous Compounds; Guinea Pigs; In Vitro Techniques; Io

1983
Cone visual cell degeneration in ground squirrel retina: disruption of morphology and cyclic nucleotide metabolism by lodoacetic acid.
    Investigative ophthalmology & visual science, 1983, Volume: 24, Issue:9

    Topics: Animals; Iodoacetates; Iodoacetic Acid; Nucleotides, Cyclic; Photoreceptor Cells; Retinal Degenerati

1983
Can potentials from the visual cortex be elicited electrically despite severe retinal degeneration and a markedly reduced electroretinogram?
    German journal of ophthalmology, 1995, Volume: 4, Issue:1

    Topics: Animals; Electric Stimulation; Electroretinography; Evoked Potentials, Visual; Iodates; Iodoacetates

1995
[Oscillatory evoked potentials in the rabbit visual system during experimental retinal pathology induced by administration of monoiodoacetic acid].
    Biulleten' eksperimental'noi biologii i meditsiny, 1985, Volume: 100, Issue:9

    Topics: Animals; Electroretinography; Evoked Potentials, Visual; Iodoacetates; Iodoacetic Acid; Rabbits; Ret

1985