iodoacetic acid has been researched along with Hypoxia in 35 studies
Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.
iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells." | 7.67 | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988) |
| "Isolated hepatocytes incubated under conditions of "chemical hypoxia" (KCN + iodoacetic acid) exhibited a marked dephosphorylation of the cytoplasmic and mitochondrial adenine nucleotides to AMP." | 3.69 | The influence of hypoxia and anoxia on distribution of adenine nucleotides in isolated hepatocytes. ( Aprille, JR; Dransfield, DT, 1994) |
| " The application of cyanide (to mimic hypoxia) produced a fall of the concentration of phosphocreatine ([PCr]) and a rise of those of inorganic phosphate ([Pi]) and sugar phosphates." | 3.68 | Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart. ( Bauer, CJ; Donoso, P; Eisner, DA; Smith, GL, 1993) |
| " Loss of cell viability and phospholipase A2 activity measured by arachidonic acid release increased in parallel during metabolic inhibition with KCN and iodoacetate (chemical hypoxia)." | 3.68 | A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. ( Harrison, DC; Herman, B; Lemasters, JJ, 1991) |
| "The purpose of this study was to determine the effects of acute hypoxia on the ATP content of, and release of adenosine from, cultured endothelial cells." | 3.67 | Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition. ( Berne, RM; Rubio, R; Shryock, JC, 1988) |
| "We studied the effects of brief periods (20-30 min) of hypoxia in the presence of 5 and 50 mM glucose and of glycolytic blockade (10(-4) M iodoacetic acid, IAA) on action potentials, membrane currents, and mechanical activity in rat ventricular papillary muscles using a single sucrose gap voltage-clamp technique." | 3.66 | Outward current and repolarization in hypoxic rat myocardium. ( Bing, OH; Conrad, CH; Mark, RG, 1983) |
| "Energy utilization during anoxia, assessed by measuring ATP fall in cyanide/iodoacetate-treated brain slices, increased with age." | 1.29 | Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia. ( Bickler, PE; Gallego, SM; Hansen, BM, 1993) |
| "During anoxia, extracellular K+ increased by approximately 10-fold (from 3." | 1.28 | Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia. ( Haddad, GG; Jiang, C; Xia, Y, 1992) |
| "Chemically induced hypoglycemia and anoxia were evaluated in embryonic day 13 chicken retina to determine if excitotoxicity was a consequence of these conditions and if this was preceded by the net release of glutamate or aspartate." | 1.28 | Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina. ( Nicklas, WJ; Zeevalk, GD, 1990) |
| "During a 3-min period of anoxia some hearts showed a decrease in systolic pressure, while other hearts developed contracture." | 1.27 | Protective effect of glucose on the anoxic myocardium of old and young mice. ( Barry, AC; Barry, GD; Zimmerman, JA, 1987) |
| "When isoproterenol was present in the bathing solution, the decreases in CF and APD produced by hypoxia were accelerated, but ATP and propranolol did not significantly modify the hypoxically induced changes." | 1.26 | Effects of hypoxia and metabolic inhibitors on the electrical and mechanical activities of isolated guinea pig papillary muscles. ( Asano, T; Kasuya, Y; Shigenobu, K, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (42.86) | 18.7374 |
| 1990's | 17 (48.57) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (5.71) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, H | 1 |
| Ding, L | 1 |
| Shi, X | 1 |
| Mei, W | 1 |
| Huang, Z | 1 |
| Zhang, L | 2 |
| Li, X | 1 |
| Xu, B | 1 |
| Wang, P | 1 |
| Wang 王宇扬, Y | 1 |
| Little, AG | 1 |
| Aristizabal, MJ | 1 |
| Robertson, RM | 1 |
| Dóra, E | 1 |
| Kovách, AG | 1 |
| Conrad, CH | 1 |
| Mark, RG | 1 |
| Bing, OH | 2 |
| Shigenobu, K | 1 |
| Asano, T | 1 |
| Kasuya, Y | 1 |
| Senges, J | 1 |
| Brachmann, J | 1 |
| Pelzer, D | 1 |
| Rizos, I | 1 |
| Kübler, W | 1 |
| Savineau, JP | 1 |
| Gonzalez de la Fuente, P | 1 |
| Marthan, R | 1 |
| Dransfield, DT | 1 |
| Aprille, JR | 1 |
| Zhao, W | 1 |
| Guénard, H | 1 |
| Bickler, PE | 2 |
| Gallego, SM | 1 |
| Hansen, BM | 1 |
| Smith, GL | 1 |
| Donoso, P | 1 |
| Bauer, CJ | 1 |
| Eisner, DA | 1 |
| Mayorga, LS | 1 |
| De Veca, MG | 1 |
| Colombo, MI | 1 |
| Bertini, F | 1 |
| Kelly, MJ | 1 |
| Richardson, W | 1 |
| Hartmund, T | 1 |
| Gesser, H | 1 |
| Dux, E | 1 |
| Oschlies, U | 1 |
| Uto, A | 1 |
| Kusumoto, M | 1 |
| Hossmann, KA | 1 |
| Dizon, J | 1 |
| Burkhoff, D | 1 |
| Tauskela, J | 1 |
| Whang, J | 1 |
| Cannon, P | 1 |
| Katz, J | 1 |
| Lu, GW | 1 |
| Cui, XY | 1 |
| Zhao, BM | 1 |
| Matsuki, N | 1 |
| Inaba, M | 1 |
| Ono, K | 1 |
| Xia, Y | 1 |
| Jiang, C | 1 |
| Haddad, GG | 1 |
| Zeevalk, GD | 2 |
| Nicklas, WJ | 2 |
| Kelleher, JA | 1 |
| Weinberg, JM | 1 |
| Buchanan, DN | 1 |
| Davis, JA | 1 |
| Abarzua, M | 1 |
| Harrison, DC | 1 |
| Lemasters, JJ | 1 |
| Herman, B | 1 |
| Lukashin, VG | 1 |
| Vshivtseva, VV | 1 |
| Zamuraev, IN | 1 |
| Chih, CP | 1 |
| Feng, ZC | 1 |
| Rosenthal, M | 1 |
| Lutz, PL | 1 |
| Sick, TJ | 1 |
| Brooks, WW | 1 |
| Ekblom, B | 1 |
| Nicotera, P | 1 |
| Thor, H | 1 |
| Orrenius, S | 1 |
| Shryock, JC | 1 |
| Rubio, R | 1 |
| Berne, RM | 1 |
| Coetzee, WA | 1 |
| Opie, LH | 1 |
| Barry, AC | 1 |
| Barry, GD | 1 |
| Zimmerman, JA | 1 |
| Abrahamsen, J | 1 |
| Nedergaard, OA | 1 |
| Weiss, J | 1 |
| Hiltbrand, B | 1 |
| Ishikawa, S | 1 |
| Vassalle, M | 1 |
| Paddle, BM | 1 |
35 other studies available for iodoacetic acid and Hypoxia
| Article | Year |
|---|---|
Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis.
Topics: Animals; Biomarkers; Disease Models, Animal; Down-Regulation; Fibroblasts; Fibrosis; Furocoumarins; | 2021 |
Low Glycolysis Is Neuroprotective during Anoxic Spreading Depolarization (SD) and Reoxygenation in Locusts.
Topics: Animals; Carbon Dioxide; Female; Glucose; Glycolysis; Grasshoppers; Hypoxia; Iodoacetic Acid | 2023 |
Glycolysis and regulation of cerebral blood flow and metabolism.
Topics: Animals; Brain; Cats; Cerebrovascular Circulation; Glycolysis; Hypoxia; Iodoacetates; Iodoacetic Aci | 1984 |
Outward current and repolarization in hypoxic rat myocardium.
Topics: Action Potentials; Aerobiosis; Anaerobiosis; Animals; Glucose; Glycolysis; Heart; Hypoxia; Iodoaceta | 1983 |
Effects of hypoxia and metabolic inhibitors on the electrical and mechanical activities of isolated guinea pig papillary muscles.
Topics: 2,4-Dinitrophenol; Action Potentials; Adenosine Triphosphate; Animals; Dinitrophenols; Guinea Pigs; | 1981 |
Effect of glycolytic inhibitors on the sinoatrial node, atrium and atrioventricular node in the rabbit heart.
Topics: Action Potentials; Aerobiosis; Animals; Atrioventricular Node; Deoxy Sugars; Deoxyglucose; Dose-Resp | 1981 |
Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.
Topics: Aged; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Glyburide; Humans; Hypoxia; In Vi | 1995 |
The influence of hypoxia and anoxia on distribution of adenine nucleotides in isolated hepatocytes.
Topics: Adenine Nucleotides; Animals; Cytoplasm; Fructose; Glucose; Hypoxia; Iodoacetates; Iodoacetic Acid; | 1994 |
Bronchial smooth muscle energetics: effect of iodoacetate and hypoxia.
Topics: Animals; Bronchi; Carbachol; Cattle; Energy Metabolism; Hypoxia; In Vitro Techniques; Iodoacetates; | 1994 |
Developmental changes in intracellular calcium regulation in rat cerebral cortex during hypoxia.
Topics: Adenosine Triphosphate; Aging; Animals; Calcium; Cerebral Cortex; Cyanides; Glutamates; Glutamic Aci | 1993 |
Relationship between intracellular pH and metabolite concentrations during metabolic inhibition in isolated ferret heart.
Topics: Acidosis; Adenosine Triphosphate; Animals; Cyanides; Ferrets; Glycolysis; Heart; Hydrogen-Ion Concen | 1993 |
Effect of pH and ATP on the equilibrium density of lysosomes.
Topics: Adenosine Triphosphate; Animals; Deoxyglucose; Endocytosis; Ethylmaleimide; Hydrogen-Ion Concentrati | 1993 |
Possible mechanisms for the protective action of alpha-tocopherol in vascular hypoxia.
Topics: Animals; Antioxidants; Calcium; Cocaine; Female; Glycolysis; Guinea Pigs; Hypoxia; In Vitro Techniqu | 1996 |
Cardiac force and high-energy phosphates under metabolic inhibition in four ectothermic vertebrates.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Creatine; Creatine | 1996 |
Early ultrastructural changes after brief histotoxic hypoxia in cultured cortical and hippocampal CA1 neurons.
Topics: Animals; Cells, Cultured; Cerebral Cortex; Cytoplasm; Hippocampus; Hypoxia; Iodoacetates; Iodoacetic | 1996 |
Metabolic inhibition in the perfused rat heart: evidence for glycolytic requirement for normal sodium homeostasis.
Topics: Animals; Calcium; Cardiac Pacing, Artificial; Energy Metabolism; Glycolysis; Homeostasis; Hypoxia; I | 1998 |
Alteration of oxygen consumption and energy metabolism during repetitive exposure of mice to hypoxia.
Topics: Animals; Body Temperature; Energy Metabolism; Female; Hypoxia; Iodoacetic Acid; Male; Malonates; Mic | 1999 |
Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia.
Topics: Adenine Nucleotides; Allantoin; Animals; Cells, Cultured; Cytoplasm; Glycolysis; Hypoxia; Iodoacetic | 2002 |
Oxidative and glycolytic pathways in rat (newborn and adult) and turtle brain: role during anoxia.
Topics: Aging; Animals; Animals, Newborn; Brain; Electron Transport Complex IV; Glycolysis; Hexokinase; Hypo | 1992 |
NMDA receptors, cellular edema, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Chickens; Dizocilpine Maleate; Edema; Electron Transp | 1992 |
Fructose-1,6-bisphosphate stabilizes brain intracellular calcium during hypoxia in rats.
Topics: Adenosine Triphosphate; Animals; Brain; Calcium; Fructosediphosphates; Glycolysis; Hydrogen-Ion Conc | 1992 |
Metabolic aspects of protection by glycine against hypoxic injury to isolated proximal tubules.
Topics: Animals; Antimetabolites; Butyrates; Butyric Acid; Culture Media; Deoxyglucose; Glycine; Hypoxia; In | 1991 |
A pH-dependent phospholipase A2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Membrane; Cell Survival; Cells, Cultured; Hydroge | 1991 |
Chemically induced hypoglycemia and anoxia: relationship to glutamate receptor-mediated toxicity in retina.
Topics: Adenosine Triphosphate; Amino Acids; Animals; Aspartic Acid; Chick Embryo; Electron Transport; Glyco | 1990 |
[Functional restructuring of the bush-like receptor during the suppression of anaerobic glycolysis].
Topics: Action Potentials; Anaerobiosis; Animals; Cytophotometry; Depression, Chemical; Glucose; Glycolysis; | 1989 |
Energy metabolism, ion homeostasis, and evoked potentials in anoxic turtle brain.
Topics: Animals; Brain; Cerebrovascular Circulation; Energy Metabolism; Evoked Potentials; Homeostasis; Hypo | 1989 |
Comparative response of 2-week and 6-month old rat myocardium to hypoxia.
Topics: Adrenergic beta-Antagonists; Animals; Glucose; Heart; Hypoxia; Iodoacetates; Iodoacetic Acid; Male; | 1985 |
Cytosolic-free Ca2+ and cell killing in hepatoma 1c1c7 cells exposed to chemical anoxia.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Membrane; Cell Survival; Cytosol; Glutathione; Hypoxi | 1989 |
Release of adenosine from pig aortic endothelial cells during hypoxia and metabolic inhibition.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Cells, Cultured; Dipyridamole; Endothelium, Vascu | 1988 |
Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle.
Topics: Acidosis; Action Potentials; Animals; Coronary Disease; Cyanides; Deoxyglucose; Guinea Pigs; Heart C | 1987 |
Protective effect of glucose on the anoxic myocardium of old and young mice.
Topics: Aging; Animals; Glucose; Glycogen; Heart; Hypoxia; In Vitro Techniques; Iodoacetates; Iodoacetic Aci | 1987 |
Accumulation of 3H-adrenaline by rabbit aorta.
Topics: Animals; Aorta; Catechol O-Methyltransferase Inhibitors; Clonidine; Cocaine; Desipramine; Epinephrin | 1985 |
Functional compartmentation of glycolytic versus oxidative metabolism in isolated rabbit heart.
Topics: Animals; Azides; Dinitrophenols; Glycolysis; Heart; Hypoxia; In Vitro Techniques; Iodoacetates; Iodo | 1985 |
Reversal of strophanthidin negative inotropy by metabolic substrates in cardiac Purkinje fibres.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Calcium; Depression, Chemical; Dogs; Female; Gluc | 1985 |
A cytoplasmic component of pyridine nucleotide fluorescence in rat diaphragm: evidence from comparisons with flavoprotein fluorescence.
Topics: Aerobiosis; Animals; Cytoplasm; Diaphragm; Female; Flavoproteins; Fluorescence; Homeostasis; Hypoxia | 1985 |