iodoacetic acid has been researched along with Disease Exacerbation in 14 studies
Iodoacetic Acid: A derivative of ACETIC ACID that contains one IODINE atom attached to its methyl group.
iodoacetic acid : A haloacetic acid that is acetic acid in which one of the hydrogens of the methyl group is replaced by an iodine atom.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In contrast, we observed persistent joint pain after day 10 in the high-dose group." | 1.51 | Time course analyses of structural changes in the infrapatellar fat pad and synovial membrane during inflammation-induced persistent pain development in rat knee joint. ( Akiyama, M; Hoshino, T; Inomata, K; Katagiri, H; Koga, H; Miyatake, K; Muneta, T; Nakagawa, Y; Onuma, H; Sekiya, I; Tsuji, K; Udo, M, 2019) |
| "Chronic inflammation is one of the major causes of cartilage destruction in osteoarthritis." | 1.37 | Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis. ( Agarwal, S; Butterfield, TA; Deschner, J; Gassner, R; Liu, J; Nam, J; Perera, P; Rath, B, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (71.43) | 24.3611 |
| 2020's | 4 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Piao, S | 1 |
| Du, W | 1 |
| Wei, Y | 1 |
| Yang, Y | 1 |
| Feng, X | 1 |
| Bai, L | 1 |
| Lee, D | 1 |
| Ju, MK | 1 |
| Kim, H | 1 |
| Lakshmanan, DK | 1 |
| Ravichandran, G | 1 |
| Elangovan, A | 1 |
| Jeyapaul, P | 1 |
| Murugesan, S | 1 |
| Thilagar, S | 1 |
| Bryk, M | 1 |
| Chwastek, J | 1 |
| Kostrzewa, M | 1 |
| Mlost, J | 1 |
| Pędracka, A | 1 |
| Starowicz, K | 1 |
| Unger, MD | 1 |
| Murthy, NS | 1 |
| Kanwar, R | 1 |
| Strand, KA | 1 |
| Maus, TP | 1 |
| Beutler, AS | 1 |
| Hoshino, T | 2 |
| Tsuji, K | 2 |
| Onuma, H | 2 |
| Udo, M | 2 |
| Ueki, H | 1 |
| Akiyama, M | 2 |
| Abula, K | 1 |
| Katagiri, H | 2 |
| Miyatake, K | 2 |
| Watanabe, T | 1 |
| Sekiya, I | 2 |
| Koga, H | 2 |
| Muneta, T | 2 |
| Lockwood, SM | 1 |
| Bannister, K | 1 |
| Dickenson, AH | 1 |
| Inomata, K | 1 |
| Nakagawa, Y | 1 |
| Thote, T | 1 |
| Lin, AS | 1 |
| Raji, Y | 1 |
| Moran, S | 1 |
| Stevens, HY | 1 |
| Hart, M | 1 |
| Kamath, RV | 1 |
| Guldberg, RE | 1 |
| Willett, NJ | 1 |
| Xu, YK | 1 |
| Ke, Y | 1 |
| Wang, B | 1 |
| Lin, JH | 1 |
| Miyamoto, S | 1 |
| Nakamura, J | 1 |
| Ohtori, S | 2 |
| Orita, S | 2 |
| Omae, T | 1 |
| Nakajima, T | 1 |
| Suzuki, T | 1 |
| Takahashi, K | 2 |
| Nam, J | 2 |
| Perera, P | 2 |
| Liu, J | 2 |
| Wu, LC | 1 |
| Rath, B | 2 |
| Butterfield, TA | 2 |
| Agarwal, S | 2 |
| Ishikawa, T | 1 |
| Miyagi, M | 1 |
| Ochiai, N | 1 |
| Inoue, G | 1 |
| Eguchi, Y | 1 |
| Kamoda, H | 1 |
| Arai, G | 1 |
| Toyone, T | 1 |
| Aoki, Y | 1 |
| Kubo, T | 1 |
| Deschner, J | 1 |
| Gassner, R | 1 |
14 other studies available for iodoacetic acid and Disease Exacerbation
| Article | Year |
|---|---|
Protectin DX attenuates IL-1β-induced inflammation via the AMPK/NF-κB pathway in chondrocytes and ameliorates osteoarthritis progression in a rat model.
Topics: AMP-Activated Protein Kinases; Animals; Arthritis, Experimental; Cells, Cultured; Chondrocytes; Dise | 2020 |
Commiphora Extract Mixture Ameliorates Monosodium Iodoacetate-Induced Osteoarthritis.
Topics: Acetic Acid; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Cartilage, Arti | 2020 |
Topics: Animals; Cissus; Disease Models, Animal; Disease Progression; Female; India; Iodoacetic Acid; Knee J | 2020 |
Alterations in Anandamide Synthesis and Degradation during Osteoarthritis Progression in an Animal Model.
Topics: Animals; Arachidonic Acids; Disease Models, Animal; Disease Progression; Endocannabinoids; Gene Expr | 2020 |
Clinical magnetic resonance-enabled characterization of mono-iodoacetate-induced osteoarthritis in a large animal species.
Topics: Animals; Body Size; Disease Models, Animal; Disease Progression; Humans; Injections, Intra-Articular | 2018 |
Persistent synovial inflammation plays important roles in persistent pain development in the rat knee before cartilage degradation reaches the subchondral bone.
Topics: Animals; Arthralgia; Avoidance Learning; Behavior, Animal; Calcitonin Gene-Related Peptide; Cartilag | 2018 |
An investigation into the noradrenergic and serotonergic contributions of diffuse noxious inhibitory controls in a monoiodoacetate model of osteoarthritis.
Topics: Action Potentials; Adrenergic alpha-2 Receptor Antagonists; Animals; Diffuse Noxious Inhibitory Cont | 2019 |
Time course analyses of structural changes in the infrapatellar fat pad and synovial membrane during inflammation-induced persistent pain development in rat knee joint.
Topics: Adipose Tissue; Animals; Arthralgia; Arthritis, Experimental; Behavior, Animal; Disease Progression; | 2019 |
Localized 3D analysis of cartilage composition and morphology in small animal models of joint degeneration.
Topics: Animals; Arthritis, Experimental; Cartilage, Articular; Disease Models, Animal; Disease Progression; | 2013 |
The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis.
Topics: Adolescent; Aged; Animals; Apoptosis; Chemokine CCL2; Chondrocytes; Disease Progression; Enzyme-Link | 2015 |
Intra-articular injection of mono-iodoacetate induces osteoarthritis of the hip in rats.
Topics: Animals; Disease Models, Animal; Disease Progression; Hip Joint; Injections, Intra-Arterial; Iodoace | 2016 |
Transcriptome-wide gene regulation by gentle treadmill walking during the progression of monoiodoacetate-induced arthritis.
Topics: Animals; Arthritis, Experimental; Cartilage; Disease Progression; Exercise Test; Exercise Therapy; F | 2011 |
Pain-related sensory innervation in monoiodoacetate-induced osteoarthritis in rat knees that gradually develops neuronal injury in addition to inflammatory pain.
Topics: Animals; Arthralgia; Chronic Disease; Disease Models, Animal; Disease Progression; Female; Inflammat | 2011 |
Sequential alterations in catabolic and anabolic gene expression parallel pathological changes during progression of monoiodoacetate-induced arthritis.
Topics: Animals; Arthritis; Bone and Bones; Cartilage, Articular; Cell Proliferation; Cluster Analysis; Dise | 2011 |