iodoacetamide has been researched along with Melanoma in 4 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Challenge of human or murine melanoma cells with sodium arsenite, heavy metals (Zn2+, Cu2+ and Cd2+), or thiol-reactive agents (p-chloromercuribenzoate and iodoacetamide) induced the synthesis of four stress proteins with molecular masses of 100, 90, 72 (a doublet), and 32 (human) or 34 (murine) kDa." | 3.67 | Induction of 32- and 34-kDa stress proteins by sodium arsenite, heavy metals, and thiol-reactive agents. ( Caltabiano, MM; Greig, RG; Koestler, TP; Poste, G, 1986) |
| "On the contrary, cancer cells isolated from tumor tissues possessed and released a factor VII independent activity which was inhibited by iodoacetamide of HgCl2 and was not modified by concanavalin A." | 1.29 | Different expression of procoagulant activity in human cancer cells cultured "in vitro" or in cells isolated from human tumor tissues. ( Grignani, G; Pacchiarini, L; Saporiti, A; Tacconi, F; Zucchella, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mojamdar, M | 1 |
| Ichihashi, M | 1 |
| Mishima, Y | 1 |
| Bystryn, JC | 1 |
| Perlstein, J | 1 |
| Zucchella, M | 1 |
| Pacchiarini, L | 1 |
| Tacconi, F | 1 |
| Saporiti, A | 1 |
| Grignani, G | 1 |
| Caltabiano, MM | 1 |
| Koestler, TP | 1 |
| Poste, G | 1 |
| Greig, RG | 1 |
4 other studies available for iodoacetamide and Melanoma
| Article | Year |
|---|---|
Tyrosinase and gamma-glutamyl transpeptidase in 5-s-cysteinyldopa genesis within melanotic and amelanotic melanomas.
Topics: Catechol Oxidase; Cysteinyldopa; Dihydroxyphenylalanine; Ditiocarb; gamma-Glutamyltransferase; Human | 1982 |
Autocatabolism of surface macromolecules shed by human melanoma cells.
Topics: 2,4-Dinitrophenol; Cell Membrane; Cells, Cultured; Cytochalasin B; Deoxyglucose; Dinitrophenols; Hum | 1982 |
Different expression of procoagulant activity in human cancer cells cultured "in vitro" or in cells isolated from human tumor tissues.
Topics: Blood Coagulation Factors; Concanavalin A; Cysteine Endopeptidases; Factor VII; Factor X; Humans; Io | 1993 |
Induction of 32- and 34-kDa stress proteins by sodium arsenite, heavy metals, and thiol-reactive agents.
Topics: Amino Acids; Animals; Arsenic; Arsenites; Cadmium; Calcimycin; Chloromercuribenzoates; Copper; Cyclo | 1986 |