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iodoacetamide and Disease Models, Animal

iodoacetamide has been researched along with Disease Models, Animal in 26 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis."7.73Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006)
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis."7.70Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999)
"Nicotine treatment also significantly increased jejunal segmental weight."5.31Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001)
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy."5.31Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001)
" Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed."3.77Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011)
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis."3.73Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006)
" In this study, acetic acid colitis was induced in rats with portal vein ligation and in control groups, and iodoacetamide colitis was induced in rats with partial portal vein ligation and cirrhosis due to bile duct ligation and in control groups."3.72Experimental colitis in rats with portal hypertension and liver disease. ( Ackerman, Z; Cohen, P; Karmeli, F; Rachmilewitz, D, 2003)
"Both VSL#3 and LGG significantly ameliorated colitis induced by the sulfhydryl-blocker iodoacetamide, but had no effect on the immune-mediated DNBS-induced colitis."3.71Variable response to probiotics in two models of experimental colitis in rats. ( Brigidi, P; Campieri, M; Eliakim, R; Gionchetti, P; Karmeli, F; Morgenstern, S; Rachmilewitz, D; Shibolet, O; Swennen, E, 2002)
"Enoxaparin and heparin significantly ameliorated the severity of dinitrobenzene sulphonic acid- and iodoacetamide-induced colitis as demonstrated by a decrease in mucosal lesion area, colonic weight and mucosal myeloperoxidase and nitric oxide synthase activities."3.71Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats. ( Brazowski, E; Dotan, I; Halpern, Z; Hershkoviz, R; Karmeli, F; Peled, Y; Rachmilewitz, D, 2001)
"A rat model of experimental colitis and jejunitis induced by iodoacetamide (IA), a sulphydryl blocker is accompanied by increased leukotriene, prostaglandin E2 (PGE2) generation, and nitric oxide synthase (NOS) activity."3.70Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle. ( Alpers, DH; Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Shao, JS, 1999)
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis."3.70Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999)
"Treatment with quinpirole decreased the size of colonic lesions in rats with iodoacetamide-induced UC (p < 0."1.42Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease. ( Ahluwalia, A; Deng, X; Ostapchenko, L; Paunovic, B; Prysiazhniuk, A; Sandor, Z; Szabo, S; Tarnawski, A; Tolstanova, G, 2015)
"The experimental ulcerative colitis model used in the present study resembles, to a great extent, the human disease."1.35Inflammatory bowel disease in rats: bacterial and chemical interaction. ( Barada, K; Freund, JN; Hajj Hussein, IA; Jurjus, A; Jurjus, RA; Karam, W; Mostafa, MH; Tohme, R, 2008)
"Nicotine treatment also significantly increased jejunal segmental weight."1.31Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001)
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy."1.31Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001)
"We tried to produce a new ulcerative colitis model in rats by topical administration of sulfhydryl blockers."1.30New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis. ( Sato, F; Satoh, H; Szabo, S; Takami, K, 1997)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (23.08)18.2507
2000's13 (50.00)29.6817
2010's5 (19.23)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Zou, X1
Wang, Y2
Yang, J1
Guo, H1
Cai, Z1
Hagiwara, SI1
Kaushal, E1
Paruthiyil, S1
Pasricha, PJ2
Hasdemir, B1
Bhargava, A1
Tolstanova, G3
Deng, X3
Ahluwalia, A2
Paunovic, B2
Prysiazhniuk, A1
Ostapchenko, L1
Tarnawski, A2
Sandor, Z4
Szabo, S5
Hajj Hussein, IA1
Tohme, R1
Barada, K2
Mostafa, MH1
Freund, JN1
Jurjus, RA1
Karam, W1
Jurjus, A2
Khomenko, T2
Chen, L2
Krolczyk, G1
Gil, K1
Zurowski, D1
Jung, A1
Thor, PJ1
Garg, P1
Sitaraman, SV1
Shiloach, J1
Jagtap, AG1
Niphadkar, PV1
Phadke, AS1
Ozaki, N1
Bielefeldt, K1
Sengupta, JN1
Gebhart, GF1
Shibolet, O1
Karmeli, F7
Eliakim, R3
Swennen, E1
Brigidi, P1
Gionchetti, P1
Campieri, M1
Morgenstern, S1
Rachmilewitz, D7
Ackerman, Z1
Cohen, P3
Pérez-Navarro, R1
Ballester, I1
Zarzuelo, A1
Sánchez de Medina, F1
Khoury, N1
Assef, MD1
Foltzer, CJ1
Reimund, JM1
Kedinger, M1
Elseweidy, MM1
Younis, NN1
Amin, RS1
Abdallah, FR1
Fathy, AM1
Yousif, ZA1
Liu, LS1
Winston, JH1
Shenoy, MM1
Song, GQ1
Chen, JD1
Kusstatscher, S1
Szeli, D1
Dial, EJ1
Hall, LR1
Romero, JJ1
Lichtenberger, LM1
Satoh, H1
Sato, F1
Takami, K1
Okon, E2
Shao, JS1
Alpers, DH1
Ablin, J1
Shalev, O1
Heyman, SN1
Dotan, I1
Hershkoviz, R1
Brazowski, E1
Peled, Y1
Halpern, Z1
Barada, KA1
Kafrouni, MI1
Khoury, CI1
Saade, NE1
Mourad, FH1
Szabo, SS1
Nassar, CF1

Other Studies

26 other studies available for iodoacetamide and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Paeoniflorin Alleviates Abnormalities in Rats with Functional Dyspepsia by Stimulating the Release of Acetylcholine.
    Drug design, development and therapy, 2020, Volume: 14

    Topics: Acetylcholine; Animals; Clonidine; Disease Models, Animal; Dyspepsia; Glucosides; Iodoacetamide; Mal

2020
Gastric corticotropin-releasing factor influences mast cell infiltration in a rat model of functional dyspepsia.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Animals; Behavior, Animal; Cell Count; Corticotropin-Releasing Hormone; Disease Models, Animal; Dysp

2018
Role of Dopamine and D2 Dopamine Receptor in the Pathogenesis of Inflammatory Bowel Disease.
    Digestive diseases and sciences, 2015, Volume: 60, Issue:10

    Topics: Animals; Biopsy, Needle; Blotting, Western; Cabergoline; Capillary Permeability; Colitis, Ulcerative

2015
Inflammatory bowel disease in rats: bacterial and chemical interaction.
    World journal of gastroenterology, 2008, Jul-07, Volume: 14, Issue:25

    Topics: Animals; Colitis, Ulcerative; Colon, Descending; Disease Models, Animal; Enteropathogenic Escherichi

2008
Neutralizing anti-vascular endothelial growth factor (VEGF) antibody reduces severity of experimental ulcerative colitis in rats: direct evidence for the pathogenic role of VEGF.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 328, Issue:3

    Topics: Animals; Antibodies; Cell Membrane Permeability; Colitis, Ulcerative; Colon; Disease Models, Animal;

2009
The vagal afferents discharge and myoelectrical activity in the gastric hyperalgesia model in rats.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59, Issue:4

    Topics: Animals; Disease Models, Animal; Duodenum; Electromyography; Fourier Analysis; Gastric Mucosa; Gastr

2008
Role of anti-angiogenic factor endostatin in the pathogenesis of experimental ulcerative colitis.
    Life sciences, 2011, Jan-03, Volume: 88, Issue:1-2

    Topics: Animals; Blotting, Western; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; End

2011
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:5

    Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma

2011
Models of gastric hyperalgesia in the rat.
    American journal of physiology. Gastrointestinal and liver physiology, 2002, Volume: 283, Issue:3

    Topics: Acetic Acid; Animals; Avoidance Learning; Behavior, Animal; Catheterization; Disease Models, Animal;

2002
Variable response to probiotics in two models of experimental colitis in rats.
    Inflammatory bowel diseases, 2002, Volume: 8, Issue:6

    Topics: Alkylating Agents; Animals; Benzenesulfonates; Bifidobacterium; Colitis; Disease Models, Animal; Int

2002
Experimental colitis in rats with portal hypertension and liver disease.
    Inflammatory bowel diseases, 2003, Volume: 9, Issue:1

    Topics: Alkylating Agents; Amino Acids; Animals; Bile Ducts; Colitis; Disease Models, Animal; Hemodynamics;

2003
Disturbances in epithelial ionic secretion in different experimental models of colitis.
    Life sciences, 2005, Feb-11, Volume: 76, Issue:13

    Topics: Acetic Acid; Acute Disease; Alkylating Agents; Animals; Animals, Genetically Modified; Chloramines;

2005
Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:11

    Topics: Aminopeptidases; Animals; Colitis; Colon; Disease Models, Animal; Female; Gene Expression Regulation

2006
Effect of some natural products either alone or in combination on gastritis induced in experimental rats.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:7

    Topics: Administration, Oral; Analysis of Variance; Animals; Curcuma; Disease Models, Animal; Fatty Acids, O

2008
A rat model of chronic gastric sensorimotor dysfunction resulting from transient neonatal gastric irritation.
    Gastroenterology, 2008, Volume: 134, Issue:7

    Topics: Age Factors; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Catheterization; Chronic Dise

2008
[The effect of thrombocyte-derived growth factor on experimental inflammatory bowel disease].
    Orvosi hetilap, 1995, May-14, Volume: 136, Issue:20

    Topics: Animals; Disease Models, Animal; Inflammatory Bowel Diseases; Iodoacetamide; Platelet-Derived Growth

1995
Rats with gastritis have increased sensitivity to the gastrin stimulatory effects of luminal ammonia.
    Gastroenterology, 1996, Volume: 110, Issue:3

    Topics: Acetates; Ammonia; Animals; Disease Models, Animal; Gastric Mucosa; Gastrins; Gastritis; Iodoacetami

1996
New ulcerative colitis model induced by sulfhydryl blockers in rats and the effects of antiinflammatory drugs on the colitis.
    Japanese journal of pharmacology, 1997, Volume: 73, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzoquinones; Colitis,

1997
Sulphydryl blocker induced small intestinal inflammation in rats: a new model mimicking Crohn's disease.
    Gut, 1997, Volume: 41, Issue:3

    Topics: Acetophenones; Animals; Antioxidants; Crohn Disease; Cyclic N-Oxides; Disease Models, Animal; Enteri

1997
Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle.
    Inflammatory bowel diseases, 1999, Volume: 5, Issue:1

    Topics: Animals; Antibodies; Colitis; Disease Models, Animal; Enteritis; Injections, Intravenous; Intestinal

1999
Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats.
    Inflammatory bowel diseases, 1999, Volume: 5, Issue:4

    Topics: Acetates; Administration, Oral; Animals; Colitis; Deferiprone; Disease Models, Animal; Gastric Mucos

1999
Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats.
    International journal of colorectal disease, 2001, Volume: 16, Issue:1

    Topics: Animals; Colitis; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admin

2001
Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Benzenesulfonates; Colitis; Disease Models, Anima

2001
Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents.
    Life sciences, 2001, Nov-09, Volume: 69, Issue:25-26

    Topics: Afferent Pathways; Alanine; Animals; Animals, Newborn; Capsaicin; Colitis; Denervation; Disease Mode

2001