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iodoacetamide and Colitis

iodoacetamide has been researched along with Colitis in 18 studies

Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.

Research Excerpts

ExcerptRelevanceReference
"Escitalopram, a drug of choice in the treatment of depression, was recently shown to possess an anti-inflammatory activity."7.91Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR. ( Abdelsalam, RM; Abdo, SA; Khattab, MM; Wadie, W, 2019)
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis."7.73Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006)
"Rectal administration of iodoacetamide induces colitis by blocking sulphhydryl groups and generating inflammatory mediators."7.71Amelioration of experimental colitis by thalidomide. ( Aeed, H; Avni, Y; Bruck, R; Hershkoviz, R; Kenet, G; Shirin, H; Wardi, J; Zaidel, L, 2001)
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis."7.70Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999)
"Nicotine treatment also significantly increased jejunal segmental weight."5.31Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001)
"The latter modality is used for the treatment of colitis and hepatitis."5.31Ozone enema: a model of microscopic colitis in rats. ( Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Zimran, A, 2001)
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy."5.31Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001)
"Escitalopram, a drug of choice in the treatment of depression, was recently shown to possess an anti-inflammatory activity."3.91Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR. ( Abdelsalam, RM; Abdo, SA; Khattab, MM; Wadie, W, 2019)
" Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed."3.77Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011)
" This study describes the changes in the expression of nerve growth factor (NGF) and interleukin-10 (IL-10) in the colon and in various segments of the small intestine in two rat models of experimental colitis induced by iodoacetamide or 2,4,6-trinitrobenzene sulfonic acid (TNBS)."3.74Up-regulation of nerve growth factor and interleukin-10 in inflamed and non-inflamed intestinal segments in rats with experimental colitis. ( Barada, KA; Jurjus, A; Khoury, C; Mourad, FH; Nassar, CF; Saadé, NE; Safieh-Garabedian, B; Sawah, SI; Tawil, A, 2007)
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis."3.73Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006)
" In this study, acetic acid colitis was induced in rats with portal vein ligation and in control groups, and iodoacetamide colitis was induced in rats with partial portal vein ligation and cirrhosis due to bile duct ligation and in control groups."3.72Experimental colitis in rats with portal hypertension and liver disease. ( Ackerman, Z; Cohen, P; Karmeli, F; Rachmilewitz, D, 2003)
"Both VSL#3 and LGG significantly ameliorated colitis induced by the sulfhydryl-blocker iodoacetamide, but had no effect on the immune-mediated DNBS-induced colitis."3.71Variable response to probiotics in two models of experimental colitis in rats. ( Brigidi, P; Campieri, M; Eliakim, R; Gionchetti, P; Karmeli, F; Morgenstern, S; Rachmilewitz, D; Shibolet, O; Swennen, E, 2002)
"Enoxaparin and heparin significantly ameliorated the severity of dinitrobenzene sulphonic acid- and iodoacetamide-induced colitis as demonstrated by a decrease in mucosal lesion area, colonic weight and mucosal myeloperoxidase and nitric oxide synthase activities."3.71Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats. ( Brazowski, E; Dotan, I; Halpern, Z; Hershkoviz, R; Karmeli, F; Peled, Y; Rachmilewitz, D, 2001)
"Rectal administration of iodoacetamide induces colitis by blocking sulphhydryl groups and generating inflammatory mediators."3.71Amelioration of experimental colitis by thalidomide. ( Aeed, H; Avni, Y; Bruck, R; Hershkoviz, R; Kenet, G; Shirin, H; Wardi, J; Zaidel, L, 2001)
"A rat model of experimental colitis and jejunitis induced by iodoacetamide (IA), a sulphydryl blocker is accompanied by increased leukotriene, prostaglandin E2 (PGE2) generation, and nitric oxide synthase (NOS) activity."3.70Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle. ( Alpers, DH; Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Shao, JS, 1999)
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis."3.70Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999)
"Chemical colitis is associated with a significant decrease in jejunal net fluid absorption."1.33Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide. ( Barada, KA; Bou Rached, NA; Khoury, CI; Mourad, FH; Nassar, CF; Saadé, NE, 2006)
"Nicotine treatment also significantly increased jejunal segmental weight."1.31Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001)
"The latter modality is used for the treatment of colitis and hepatitis."1.31Ozone enema: a model of microscopic colitis in rats. ( Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Zimran, A, 2001)
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy."1.31Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001)
"Colitis was induced in rats by intracolonic administration of 0."1.29Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase. ( Karmeli, F; Okon, E; Rachmilewitz, D, 1995)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's12 (66.67)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abdo, SA1
Wadie, W1
Abdelsalam, RM1
Khattab, MM1
Jagtap, AG1
Niphadkar, PV1
Phadke, AS1
Reichmann, F1
Painsipp, E1
Holzer, P1
Shibolet, O1
Karmeli, F8
Eliakim, R4
Swennen, E1
Brigidi, P1
Gionchetti, P1
Campieri, M1
Morgenstern, S1
Rachmilewitz, D8
Ackerman, Z1
Cohen, P4
Pérez-Navarro, R1
Ballester, I1
Zarzuelo, A1
Sánchez de Medina, F1
Mourad, FH3
Barada, KA3
Bou Rached, NA1
Khoury, CI2
Saadé, NE3
Nassar, CF3
Jurjus, A2
Barada, K1
Khoury, N1
Assef, MD1
Foltzer, CJ1
Reimund, JM1
Kedinger, M1
Sawah, SI1
Khoury, C1
Safieh-Garabedian, B1
Tawil, A1
Okon, E2
Shao, JS1
Alpers, DH1
Ablin, J1
Shalev, O1
Heyman, SN1
Dotan, I1
Hershkoviz, R2
Brazowski, E1
Peled, Y1
Halpern, Z1
Kenet, G2
Wardi, J1
Avni, Y2
Aeed, H2
Shirin, H1
Zaidel, L1
Bruck, R2
Zimran, A1
Kafrouni, MI1
Szabo, SS1
Levine, A1
Avinoach, I1
Matas, Z1
David, M1
Yayon, A1

Other Studies

18 other studies available for iodoacetamide and Colitis

ArticleYear
Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR.
    Inflammation, 2019, Volume: 42, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Citalopram; Colitis; Dep

2019
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
    Indian journal of experimental biology, 2011, Volume: 49, Issue:5

    Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma

2011
Environmental enrichment and gut inflammation modify stress-induced c-Fos expression in the mouse corticolimbic system.
    PloS one, 2013, Volume: 8, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cerebral Cortex; Colitis; Dextran Sulfate; Gastritis; Gene Express

2013
Variable response to probiotics in two models of experimental colitis in rats.
    Inflammatory bowel diseases, 2002, Volume: 8, Issue:6

    Topics: Alkylating Agents; Animals; Benzenesulfonates; Bifidobacterium; Colitis; Disease Models, Animal; Int

2002
Experimental colitis in rats with portal hypertension and liver disease.
    Inflammatory bowel diseases, 2003, Volume: 9, Issue:1

    Topics: Alkylating Agents; Amino Acids; Animals; Bile Ducts; Colitis; Disease Models, Animal; Hemodynamics;

2003
Disturbances in epithelial ionic secretion in different experimental models of colitis.
    Life sciences, 2005, Feb-11, Volume: 76, Issue:13

    Topics: Acetic Acid; Acute Disease; Alkylating Agents; Animals; Animals, Genetically Modified; Chloramines;

2005
Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide.
    American journal of physiology. Gastrointestinal and liver physiology, 2006, Volume: 290, Issue:2

    Topics: Animals; Benzalkonium Compounds; Capsaicin; Colitis; Enteric Nervous System; Enzyme Inhibitors; Inte

2006
Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats.
    Canadian journal of physiology and pharmacology, 2006, Volume: 84, Issue:11

    Topics: Aminopeptidases; Animals; Colitis; Colon; Disease Models, Animal; Female; Gene Expression Regulation

2006
Up-regulation of nerve growth factor and interleukin-10 in inflamed and non-inflamed intestinal segments in rats with experimental colitis.
    Cytokine, 2007, Volume: 37, Issue:3

    Topics: Animals; Colitis; Colon; Inflammation; Interleukin-10; Intestine, Small; Iodoacetamide; Nerve Growth

2007
Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase.
    Gastroenterology, 1995, Volume: 109, Issue:1

    Topics: Amino Acid Oxidoreductases; Animals; Arginine; Colitis; Colon; Dinoprostone; Intestinal Mucosa; Iodo

1995
Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle.
    Inflammatory bowel diseases, 1999, Volume: 5, Issue:1

    Topics: Animals; Antibodies; Colitis; Disease Models, Animal; Enteritis; Injections, Intravenous; Intestinal

1999
Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats.
    Inflammatory bowel diseases, 1999, Volume: 5, Issue:4

    Topics: Acetates; Administration, Oral; Animals; Colitis; Deferiprone; Disease Models, Animal; Gastric Mucos

1999
Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats.
    International journal of colorectal disease, 2001, Volume: 16, Issue:1

    Topics: Animals; Colitis; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admin

2001
Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Benzenesulfonates; Colitis; Disease Models, Anima

2001
Amelioration of experimental colitis by thalidomide.
    The Israel Medical Association journal : IMAJ, 2001, Volume: 3, Issue:9

    Topics: Alkylating Agents; Animals; Colitis; Immunosuppressive Agents; Iodoacetamide; Rats; Thalidomide; Tum

2001
Ozone enema: a model of microscopic colitis in rats.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:11

    Topics: Administration, Rectal; Animals; Colitis; Colon; Dinoprostone; Enema; Iodoacetamide; Male; Nitric Ox

2001
Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents.
    Life sciences, 2001, Nov-09, Volume: 69, Issue:25-26

    Topics: Afferent Pathways; Alanine; Animals; Animals, Newborn; Capsaicin; Colitis; Denervation; Disease Mode

2001
Effect of heparin on tissue binding activity of fibroblast growth factor and heparin-binding epidermal growth factor in experimental colitis in rats.
    Pediatric research, 2002, Volume: 51, Issue:5

    Topics: Animals; Colitis; Drug Evaluation, Preclinical; Epidermal Growth Factor; Fibroblast Growth Factors;

2002