iodoacetamide has been researched along with Colitis in 18 studies
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
Excerpt | Relevance | Reference |
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"Escitalopram, a drug of choice in the treatment of depression, was recently shown to possess an anti-inflammatory activity." | 7.91 | Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR. ( Abdelsalam, RM; Abdo, SA; Khattab, MM; Wadie, W, 2019) |
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis." | 7.73 | Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006) |
"Rectal administration of iodoacetamide induces colitis by blocking sulphhydryl groups and generating inflammatory mediators." | 7.71 | Amelioration of experimental colitis by thalidomide. ( Aeed, H; Avni, Y; Bruck, R; Hershkoviz, R; Kenet, G; Shirin, H; Wardi, J; Zaidel, L, 2001) |
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis." | 7.70 | Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999) |
"Nicotine treatment also significantly increased jejunal segmental weight." | 5.31 | Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001) |
"The latter modality is used for the treatment of colitis and hepatitis." | 5.31 | Ozone enema: a model of microscopic colitis in rats. ( Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Zimran, A, 2001) |
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy." | 5.31 | Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001) |
"Escitalopram, a drug of choice in the treatment of depression, was recently shown to possess an anti-inflammatory activity." | 3.91 | Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR. ( Abdelsalam, RM; Abdo, SA; Khattab, MM; Wadie, W, 2019) |
" Subsequently, its protective effect in indomethacin and iodoacetamide induced colitis in rats (45, 90, 180, 270 mg/kg) and acetic acid induced colitis in mice (65, 130, 250, 500 mg/kg) was assessed." | 3.77 | Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice. ( Jagtap, AG; Niphadkar, PV; Phadke, AS, 2011) |
" This study describes the changes in the expression of nerve growth factor (NGF) and interleukin-10 (IL-10) in the colon and in various segments of the small intestine in two rat models of experimental colitis induced by iodoacetamide or 2,4,6-trinitrobenzene sulfonic acid (TNBS)." | 3.74 | Up-regulation of nerve growth factor and interleukin-10 in inflamed and non-inflamed intestinal segments in rats with experimental colitis. ( Barada, KA; Jurjus, A; Khoury, C; Mourad, FH; Nassar, CF; Saadé, NE; Safieh-Garabedian, B; Sawah, SI; Tawil, A, 2007) |
"This study aims to describe the morphological alterations in the small and large intestines as well as the expression of some enterocyte enzymes and carriers in a rat model of iodoacetamide-induced colitis." | 3.73 | Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats. ( Assef, MD; Barada, K; Foltzer, CJ; Jurjus, A; Kedinger, M; Khoury, N; Reimund, JM, 2006) |
" In this study, acetic acid colitis was induced in rats with portal vein ligation and in control groups, and iodoacetamide colitis was induced in rats with partial portal vein ligation and cirrhosis due to bile duct ligation and in control groups." | 3.72 | Experimental colitis in rats with portal hypertension and liver disease. ( Ackerman, Z; Cohen, P; Karmeli, F; Rachmilewitz, D, 2003) |
"Both VSL#3 and LGG significantly ameliorated colitis induced by the sulfhydryl-blocker iodoacetamide, but had no effect on the immune-mediated DNBS-induced colitis." | 3.71 | Variable response to probiotics in two models of experimental colitis in rats. ( Brigidi, P; Campieri, M; Eliakim, R; Gionchetti, P; Karmeli, F; Morgenstern, S; Rachmilewitz, D; Shibolet, O; Swennen, E, 2002) |
"Enoxaparin and heparin significantly ameliorated the severity of dinitrobenzene sulphonic acid- and iodoacetamide-induced colitis as demonstrated by a decrease in mucosal lesion area, colonic weight and mucosal myeloperoxidase and nitric oxide synthase activities." | 3.71 | Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats. ( Brazowski, E; Dotan, I; Halpern, Z; Hershkoviz, R; Karmeli, F; Peled, Y; Rachmilewitz, D, 2001) |
"Rectal administration of iodoacetamide induces colitis by blocking sulphhydryl groups and generating inflammatory mediators." | 3.71 | Amelioration of experimental colitis by thalidomide. ( Aeed, H; Avni, Y; Bruck, R; Hershkoviz, R; Kenet, G; Shirin, H; Wardi, J; Zaidel, L, 2001) |
"A rat model of experimental colitis and jejunitis induced by iodoacetamide (IA), a sulphydryl blocker is accompanied by increased leukotriene, prostaglandin E2 (PGE2) generation, and nitric oxide synthase (NOS) activity." | 3.70 | Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle. ( Alpers, DH; Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Shao, JS, 1999) |
" Our aim is to determine the antiinflammatory activity of deferiprone, an oral iron chelator, in experimental colitis and gastritis." | 3.70 | Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats. ( Ablin, J; Karmeli, F; Okon, E; Rachmilewitz, D; Shalev, O, 1999) |
"Chemical colitis is associated with a significant decrease in jejunal net fluid absorption." | 1.33 | Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide. ( Barada, KA; Bou Rached, NA; Khoury, CI; Mourad, FH; Nassar, CF; Saadé, NE, 2006) |
"Nicotine treatment also significantly increased jejunal segmental weight." | 1.31 | Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats. ( Cohen, P; Eliakim, R; Heyman, SN; Karmeli, F; Rachmilewitz, D, 2001) |
"The latter modality is used for the treatment of colitis and hepatitis." | 1.31 | Ozone enema: a model of microscopic colitis in rats. ( Cohen, P; Eliakim, R; Karmeli, F; Rachmilewitz, D; Zimran, A, 2001) |
"Colitis was more severe in rats subjected to neonatal or adult capsaicin treatment, but was not affected by subdiaphragmatic vagotomy." | 1.31 | Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents. ( Barada, KA; Kafrouni, MI; Khoury, CI; Mourad, FH; Nassar, CF; Saade, NE; Szabo, SS, 2001) |
"Colitis was induced in rats by intracolonic administration of 0." | 1.29 | Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase. ( Karmeli, F; Okon, E; Rachmilewitz, D, 1995) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (16.67) | 18.2507 |
2000's | 12 (66.67) | 29.6817 |
2010's | 3 (16.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Abdo, SA | 1 |
Wadie, W | 1 |
Abdelsalam, RM | 1 |
Khattab, MM | 1 |
Jagtap, AG | 1 |
Niphadkar, PV | 1 |
Phadke, AS | 1 |
Reichmann, F | 1 |
Painsipp, E | 1 |
Holzer, P | 1 |
Shibolet, O | 1 |
Karmeli, F | 8 |
Eliakim, R | 4 |
Swennen, E | 1 |
Brigidi, P | 1 |
Gionchetti, P | 1 |
Campieri, M | 1 |
Morgenstern, S | 1 |
Rachmilewitz, D | 8 |
Ackerman, Z | 1 |
Cohen, P | 4 |
Pérez-Navarro, R | 1 |
Ballester, I | 1 |
Zarzuelo, A | 1 |
Sánchez de Medina, F | 1 |
Mourad, FH | 3 |
Barada, KA | 3 |
Bou Rached, NA | 1 |
Khoury, CI | 2 |
Saadé, NE | 3 |
Nassar, CF | 3 |
Jurjus, A | 2 |
Barada, K | 1 |
Khoury, N | 1 |
Assef, MD | 1 |
Foltzer, CJ | 1 |
Reimund, JM | 1 |
Kedinger, M | 1 |
Sawah, SI | 1 |
Khoury, C | 1 |
Safieh-Garabedian, B | 1 |
Tawil, A | 1 |
Okon, E | 2 |
Shao, JS | 1 |
Alpers, DH | 1 |
Ablin, J | 1 |
Shalev, O | 1 |
Heyman, SN | 1 |
Dotan, I | 1 |
Hershkoviz, R | 2 |
Brazowski, E | 1 |
Peled, Y | 1 |
Halpern, Z | 1 |
Kenet, G | 2 |
Wardi, J | 1 |
Avni, Y | 2 |
Aeed, H | 2 |
Shirin, H | 1 |
Zaidel, L | 1 |
Bruck, R | 2 |
Zimran, A | 1 |
Kafrouni, MI | 1 |
Szabo, SS | 1 |
Levine, A | 1 |
Avinoach, I | 1 |
Matas, Z | 1 |
David, M | 1 |
Yayon, A | 1 |
18 other studies available for iodoacetamide and Colitis
Article | Year |
---|---|
Potential Anti-Inflammatory Effect of Escitalopram in Iodoacetamide-Induced Colitis in Depressed Ovariectomized Rats: Role of α7-nAChR.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Anti-Inflammatory Agents; Citalopram; Colitis; Dep | 2019 |
Protective effect of aqueous extract of Bombax malabaricum DC on experimental models of inflammatory bowel disease in rats and mice.
Topics: Acetic Acid; Animals; Bombax; Colitis; Disease Models, Animal; Female; India; Indomethacin; Inflamma | 2011 |
Environmental enrichment and gut inflammation modify stress-induced c-Fos expression in the mouse corticolimbic system.
Topics: Animals; Behavior, Animal; Brain; Cerebral Cortex; Colitis; Dextran Sulfate; Gastritis; Gene Express | 2013 |
Variable response to probiotics in two models of experimental colitis in rats.
Topics: Alkylating Agents; Animals; Benzenesulfonates; Bifidobacterium; Colitis; Disease Models, Animal; Int | 2002 |
Experimental colitis in rats with portal hypertension and liver disease.
Topics: Alkylating Agents; Amino Acids; Animals; Bile Ducts; Colitis; Disease Models, Animal; Hemodynamics; | 2003 |
Disturbances in epithelial ionic secretion in different experimental models of colitis.
Topics: Acetic Acid; Acute Disease; Alkylating Agents; Animals; Animals, Genetically Modified; Chloramines; | 2005 |
Inhibitory effect of experimental colitis on fluid absorption in rat jejunum: role of the enteric nervous system, VIP, and nitric oxide.
Topics: Animals; Benzalkonium Compounds; Capsaicin; Colitis; Enteric Nervous System; Enzyme Inhibitors; Inte | 2006 |
Morphological and biochemical alterations in the jejunum following iodoacetamide-induced colitis in rats.
Topics: Aminopeptidases; Animals; Colitis; Colon; Disease Models, Animal; Female; Gene Expression Regulation | 2006 |
Up-regulation of nerve growth factor and interleukin-10 in inflamed and non-inflamed intestinal segments in rats with experimental colitis.
Topics: Animals; Colitis; Colon; Inflammation; Interleukin-10; Intestine, Small; Iodoacetamide; Nerve Growth | 2007 |
Sulfhydryl blocker-induced rat colonic inflammation is ameliorated by inhibition of nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Colitis; Colon; Dinoprostone; Intestinal Mucosa; Iodo | 1995 |
Sulphydryl blocker-induced rat colitis is ameliorated by intravenous injection of antibody to colonic surfactant-like particle.
Topics: Animals; Antibodies; Colitis; Disease Models, Animal; Enteritis; Injections, Intravenous; Intestinal | 1999 |
Deferiprone, an oral iron chelator, ameliorates experimental colitis and gastric ulceration in rats.
Topics: Acetates; Administration, Oral; Animals; Colitis; Deferiprone; Disease Models, Animal; Gastric Mucos | 1999 |
Dual effect of chronic nicotine administration: augmentation of jejunitis and amelioration of colitis induced by iodoacetamide in rats.
Topics: Animals; Colitis; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Admin | 2001 |
Heparin and low-molecular-weight heparin (enoxaparin) significantly ameliorate experimental colitis in rats.
Topics: Animals; Anti-Inflammatory Agents; Anticoagulants; Benzenesulfonates; Colitis; Disease Models, Anima | 2001 |
Amelioration of experimental colitis by thalidomide.
Topics: Alkylating Agents; Animals; Colitis; Immunosuppressive Agents; Iodoacetamide; Rats; Thalidomide; Tum | 2001 |
Ozone enema: a model of microscopic colitis in rats.
Topics: Administration, Rectal; Animals; Colitis; Colon; Dinoprostone; Enema; Iodoacetamide; Male; Nitric Ox | 2001 |
Experimental colitis decreases rat jejunal amino acid absorption: role of capsaicin sensitive primary afferents.
Topics: Afferent Pathways; Alanine; Animals; Animals, Newborn; Capsaicin; Colitis; Denervation; Disease Mode | 2001 |
Effect of heparin on tissue binding activity of fibroblast growth factor and heparin-binding epidermal growth factor in experimental colitis in rats.
Topics: Animals; Colitis; Drug Evaluation, Preclinical; Epidermal Growth Factor; Fibroblast Growth Factors; | 2002 |