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iodixanol and Thrombosis

iodixanol has been researched along with Thrombosis in 11 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.

Research Excerpts

ExcerptRelevanceReference
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."7.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Ioxaglate and iodixanol were virtually inert."5.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
" The nonionic CM iohexol triggers platelet beta-thromboglobulin (beta-TG) secretion, and thus may activate the platelets and promote thrombosis."3.70Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin. ( Buchmann, M; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)
"Both iopamidol and iodixanol treatments deceased cell viability and increased apoptosis of HUVEC and H5V cells, along with downregulated NOS and ABCG1."1.46Hypotonic contrast media is more toxic than isotonic contrast media on endothelial cells in vivo and in vitro. ( Liu, Y; Lv, S; Ren, L; Wang, P; Wang, Z, 2017)
"Although thrombus can occasionally be difficult to diagnose using structural criteria alone, it can be distinguished from other structures according to tissue characteristics."1.34Clinical utility of delayed-contrast computed tomography for tissue characterization of cardiac thrombus. ( Cham, MD; Kim, RJ; Krauser, DG; Min, JK; Tortolani, AJ; Weinsaft, JW; Yang, XJ, 2007)
"Thrombosis was measured over a blood exposure period of 2 hours by gamma camera imaging of 111In-platelets and by gamma counting of deposited 125I-fibrin."1.31Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates. ( Chronos, NA; Hanson, SR; Markou, CP, 2001)
"Ioxaglate and iodixanol were virtually inert."1.30Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood. ( Barstad, RM; Hamers, MJ; Sakariassen, KS; Stormorken, H, 1998)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (27.27)18.2507
2000's5 (45.45)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ren, L1
Wang, P1
Wang, Z1
Liu, Y1
Lv, S1
Shah, B1
Berger, JS1
Allen, N1
Guo, Y1
Sedlis, SP1
Xu, J1
Perez, A1
Attubato, M1
Slater, J1
Feit, F1
Seto, AH1
Kern, MJ1
Krauser, DG1
Cham, MD1
Tortolani, AJ1
Kim, RJ1
Yang, XJ1
Min, JK1
Weinsaft, JW1
Jones, CI1
Goodall, AH1
Le Feuvre, C1
Batisse, A1
Collet, JP1
Batisse, JP1
Choussat, R1
Beygui, F1
Helft, G1
Montalescot, G1
Metzger, JP1
Barstad, RM2
Buchmann, MS1
Hamers, MJ3
Orning, L1
Orvim, U1
Stormorken, H3
Sakariassen, KS3
Buchmann, M1
Markou, CP1
Chronos, NA1
Hanson, SR1
Schräder, R1

Trials

2 trials available for iodixanol and Thrombosis

ArticleYear
The assessment of thrombotic markers utilizing ionic versus non-ionic contrast during coronary angiography and intervention trial.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:5

    Topics: Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease; Female; Fibrinolysi

2016
Cardiac events after low osmolar ionic or isosmolar nonionic contrast media utilization in the current era of coronary angioplasty.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2006, Volume: 67, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Clopidogrel; Contrast Media; Coronary Angio

2006

Other Studies

9 other studies available for iodixanol and Thrombosis

ArticleYear
Hypotonic contrast media is more toxic than isotonic contrast media on endothelial cells in vivo and in vitro.
    Molecular medicine reports, 2017, Volume: 16, Issue:4

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily G, Member 1; Biomarkers; Cell Death; Cell Survi

2017
Does the AToMIC trial explode concerns of contrast coagulopathy?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 88, Issue:5

    Topics: Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease; Fibrinolysis; Humans; Iox

2016
Clinical utility of delayed-contrast computed tomography for tissue characterization of cardiac thrombus.
    Journal of cardiovascular computed tomography, 2007, Volume: 1, Issue:2

    Topics: Aged; Contrast Media; Heart Diseases; Humans; Male; Radiographic Image Enhancement; Thrombosis; Time

2007
Differential effects of the iodinated contrast agents Ioxaglate, Iohexol and Iodixanol on thrombus formation and fibrinolysis.
    Thrombosis research, 2003, Volume: 112, Issue:1-2

    Topics: Blood Platelets; Contrast Media; Dose-Response Relationship, Drug; Fibrinolysis; Humans; Iohexol; Io

2003
Effects of ionic and nonionic contrast media on endothelium and on arterial thrombus formation.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:6

    Topics: Angioplasty, Balloon, Coronary; Cells, Cultured; Contrast Media; Endothelium, Vascular; Female; Huma

1996
Iohexol, platelet activation and thrombosis. I. Iohexol-induced platelet secretion does not affect thrombus formation in native blood.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: beta-Thromboglobulin; Blood Donors; Blood Platelets; Collagen; Contrast Media; Dose-Response Relatio

1998
Iohexol, platelet activation and thrombosis. II. Iohexol-induced platelet secretion does not affect collagen-induced or tissue-factor-induced thrombus formation in blood that is anticoagulated with heparin and aspirin.
    Acta radiologica (Stockholm, Sweden : 1987), 1998, Volume: 39, Issue:4

    Topics: Anticoagulants; Aspirin; beta-Thromboglobulin; Blood Platelets; Collagen; Contrast Media; Drug Inter

1998
Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates.
    Thrombosis and haemostasis, 2001, Volume: 85, Issue:3

    Topics: Animals; Arteriovenous Shunt, Surgical; Blood Flow Velocity; Contrast Media; Disease Models, Animal;

2001
Ionic or non-ionic contrast media in stent placement.
    European heart journal, 2001, Volume: 22, Issue:21

    Topics: Cohort Studies; Contrast Media; Coronary Angiography; Heart Diseases; Humans; Ioxaglic Acid; Stents;

2001