iodixanol has been researched along with Renal Insufficiency, Chronic in 22 studies
iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty." | 9.24 | Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017) |
| "To determine the incidence of post-contrast acute kidney injury (PC-AKI) and presumed contrast-induced acute kidney injury (CI-AKI) following contrast-enhanced CT (CECT) with intravenous application of a reduced dose of the iso-osmolar contrast agent iodixanol in cancer patients with chronic kidney disease." | 7.96 | Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol. ( Bez, C; Hinterleitner, C; Horger, M; Werner, S, 2020) |
| "The aim of this clinical trial is to compare iodixanol with iohexol for the incidence of contrast-induced nephropathy in patients with chronic heart failure with reduced ejection fraction who are currently undergoing coronary angiography or angioplasty." | 5.24 | Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty. ( Ge, Z; Li, Y; Shi, P; Song, M; Song, T; Sun, M, 2017) |
| "Iodixanol is associated with lower rates of contrast-induced acute kidney injury (CI-AKI)." | 4.02 | Effects of a High Dose of the Contrast Medium Iodixanol on Renal Function in Patients Following Percutaneous Coronary Intervention. ( Azzalini, L; Chen, Z; Huang, L; Jin, J; Li, L; Mao, Q; Song, Y; Tong, W; Xu, Q; Xu, Z; Zhao, N; Zhao, X; Zhou, Y, 2021) |
| "To determine the incidence of post-contrast acute kidney injury (PC-AKI) and presumed contrast-induced acute kidney injury (CI-AKI) following contrast-enhanced CT (CECT) with intravenous application of a reduced dose of the iso-osmolar contrast agent iodixanol in cancer patients with chronic kidney disease." | 3.96 | Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol. ( Bez, C; Hinterleitner, C; Horger, M; Werner, S, 2020) |
| "The relative incidence of long-term adverse effects between low-osmolar contrast media (LOCM) and iso-osmolar contrast media (IOCM) after coronary angiography is still unclear." | 1.43 | Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography. ( Chang, D; Ju, S; Lu, CQ; Tang, A; Wang, YC; Zhang, SJ, 2016) |
| "The odds ratio of acute kidney failure on day 5 was 0." | 1.38 | Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease. ( Ghahramani, N; Lapsiwala, A; Parhizgar, A; Saadulla, L; Spatz, C, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (22.73) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Hami, M | 1 |
| Bigdeli, A | 1 |
| Khameneh Bagheri, R | 1 |
| Rajabi, O | 1 |
| Salehi, M | 1 |
| Zahedi Avval, F | 1 |
| Sharma, A | 1 |
| Kilari, S | 1 |
| Cai, C | 1 |
| Simeon, ML | 1 |
| Misra, S | 1 |
| Werner, S | 1 |
| Bez, C | 1 |
| Hinterleitner, C | 1 |
| Horger, M | 1 |
| Zhao, N | 1 |
| Chen, Z | 1 |
| Zhou, Y | 1 |
| Xu, Q | 1 |
| Xu, Z | 1 |
| Tong, W | 1 |
| Li, L | 1 |
| Mao, Q | 1 |
| Song, Y | 1 |
| Jin, J | 1 |
| Huang, L | 1 |
| Azzalini, L | 1 |
| Zhao, X | 1 |
| Song, T | 1 |
| Song, M | 1 |
| Ge, Z | 1 |
| Li, Y | 1 |
| Shi, P | 1 |
| Sun, M | 1 |
| Kim, J | 1 |
| Male, S | 1 |
| Jagadeesan, BD | 1 |
| Streib, C | 1 |
| Tummala, RP | 1 |
| Kofman, N | 1 |
| Margolis, G | 1 |
| Gal-Oz, A | 1 |
| Letourneau-Shesaf, S | 1 |
| Keren, G | 1 |
| Rozenbaum, Z | 1 |
| Shacham, Y | 1 |
| Chua, HR | 1 |
| Horrigan, M | 1 |
| Mcintosh, E | 1 |
| Bellomo, R | 1 |
| Choi, MJ | 1 |
| Yoon, JW | 1 |
| Han, SJ | 1 |
| Choi, HH | 1 |
| Song, YR | 1 |
| Kim, SG | 1 |
| Oh, JE | 1 |
| Lee, YK | 1 |
| Seo, JW | 1 |
| Kim, HJ | 1 |
| Noh, JW | 1 |
| Koo, JR | 1 |
| Iwama, R | 1 |
| Sato, T | 1 |
| Katayama, M | 1 |
| Shimamura, S | 1 |
| Satoh, H | 1 |
| Ichijo, T | 1 |
| Furuhama, K | 1 |
| Quintavalle, C | 1 |
| Anselmi, CV | 1 |
| De Micco, F | 1 |
| Roscigno, G | 1 |
| Visconti, G | 1 |
| Golia, B | 1 |
| Focaccio, A | 2 |
| Ricciardelli, B | 2 |
| Perna, E | 1 |
| Papa, L | 1 |
| Donnarumma, E | 1 |
| Condorelli, G | 2 |
| Briguori, C | 2 |
| Shema-Didi, L | 1 |
| Kristal, B | 1 |
| Eizenberg, S | 1 |
| Marzuq, N | 1 |
| Sussan, M | 1 |
| Feldman-Idov, Y | 1 |
| Ofir, P | 1 |
| Atar, S | 1 |
| Rezaei, Y | 1 |
| Khademvatani, K | 1 |
| Rahimi, B | 1 |
| Khoshfetrat, M | 1 |
| Arjmand, N | 1 |
| Seyyed-Mohammadzad, MH | 1 |
| Wang, YC | 1 |
| Tang, A | 1 |
| Chang, D | 1 |
| Lu, CQ | 1 |
| Zhang, SJ | 1 |
| Ju, S | 1 |
| Sanon, S | 1 |
| Barsness, GW | 1 |
| Gulati, R | 1 |
| Rudnick, MR | 1 |
| Davidson, C | 1 |
| Laskey, W | 1 |
| Stafford, JL | 1 |
| Sherwin, PF | 1 |
| Spatz, C | 1 |
| Saadulla, L | 1 |
| Lapsiwala, A | 1 |
| Parhizgar, A | 1 |
| Ghahramani, N | 1 |
| Laugharne, MJ | 1 |
| Paravasthu, M | 1 |
| Preston, A | 1 |
| Hill, KO | 1 |
| Sharma, SK | 1 |
| Kini, A | 1 |
| Colombo, A | 1 |
| Airoldi, F | 1 |
| Morici, N | 1 |
| Sangiorgi, GM | 1 |
| Violante, A | 1 |
| Montorfano, M | 1 |
| Carlino, M | 1 |
| Deray, G | 1 |
| Persson, P | 1 |
| Liss, P | 1 |
| Hansell, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512] | 254 participants (Anticipated) | Interventional | 2022-04-20 | Recruiting | |||
| Renal Insufficiency Following Contrast Media Administration Trial II (Remedial II): The RenalGuard System in High-Risk Patients for Contrast-Induced Acute Kidney Injury[NCT01098032] | Phase 3 | 294 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [NCT02070679] | Phase 3 | 284 participants (Actual) | Interventional | 2014-02-28 | Completed | ||
| Antioxidants for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization[NCT03755700] | Phase 3 | 1,000 participants (Anticipated) | Interventional | 2018-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The primary outcome measure will be the rate of development of CI-AKI in the 2 study arms (number of participants). CI-AKI is defined as an increase in the serum creatinine concentration >=0.3 mg/dL from the baseline value at 48 hours after administration of the contrast media or the need for dialysis. (NCT01098032)
Timeframe: at 48 hours following contrast exposure
| Intervention | participants (Number) |
|---|---|
| Systemic Alone Therapy Group | 146 |
| RenalGuard System Group | 146 |
1 review available for iodixanol and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Effect of nonionic radiocontrast agents on the occurrence of contrast-induced nephropathy in patients with mild-moderate chronic renal insufficiency: pooled analysis of the randomized trials.
Topics: Contrast Media; Humans; Iohexol; Iopamidol; Kidney Diseases; Randomized Controlled Trials as Topic; | 2005 |
7 trials available for iodixanol and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
The effect of curcumin in prevention of contrast nephropathy following coronary angiography or angioplasty in CKD patients.
Topics: Acute Kidney Injury; Administration, Oral; Angioplasty; Antioxidants; Contrast Media; Coronary Angio | 2019 |
Comparison of the nephrotoxic effects of iodixanol versus iohexol in patients with chronic heart failure undergoing coronary angiography or angioplasty.
Topics: Adult; Angioplasty, Balloon, Coronary; China; Contrast Media; Coronary Angiography; Double-Blind Met | 2017 |
The prevention of contrast-induced nephropathy by simultaneous hemofiltration during coronary angiographic procedures: a comparison with periprocedural hemofiltration.
Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Female; Hemofiltration; | 2014 |
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar | 2015 |
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar | 2015 |
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar | 2015 |
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar | 2015 |
Prevention of contrast-induced nephropathy with single bolus erythropoietin in patients with diabetic kidney disease: A randomized controlled trial.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Contrast Media; Coronary A | 2016 |
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont | 2016 |
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont | 2016 |
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont | 2016 |
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont | 2016 |
Nephrotoxicity of iodixanol versus ioversol in patients with chronic kidney disease: the Visipaque Angiography/Interventions with Laboratory Outcomes in Renal Insufficiency (VALOR) Trial.
Topics: Aged; Aged, 80 and over; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Diabeti | 2008 |
14 other studies available for iodixanol and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Increased fibrotic signaling in a murine model for intra-arterial contrast-induced acute kidney injury.
Topics: Acute Kidney Injury; Animals; Apoptosis; Carotid Arteries; Cell Hypoxia; Cell Proliferation; Collage | 2020 |
Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol.
Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Incidence; Male | 2020 |
Effects of a High Dose of the Contrast Medium Iodixanol on Renal Function in Patients Following Percutaneous Coronary Intervention.
Topics: Acute Kidney Injury; Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Ma | 2021 |
Safety of cerebral angiography and neuroendovascular therapy in patients with chronic kidney disease.
Topics: Aged; Cerebral Angiography; Contrast Media; Endovascular Procedures; Female; Glomerular Filtration R | 2018 |
Long-term renal outcomes and mortality following renal injury among myocardial infarction patients treated by primary percutaneous intervention.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Comorbidity; Contrast Media; Creatinine; Disease Progr | 2019 |
Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography.
Topics: Acute Kidney Injury; Age Distribution; Aged; Cohort Studies; Contrast Media; Coronary Angiography; F | 2014 |
Relationship of glomerular filtration rate based on serum iodixanol clearance to IRIS staging in cats with chronic kidney disease.
Topics: Animals; Case-Control Studies; Cat Diseases; Cats; Contrast Media; Creatinine; Female; Glomerular Fi | 2015 |
Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography.
Topics: Aged; Cause of Death; China; Contrast Media; Coronary Angiography; Female; Heart Failure; Humans; In | 2016 |
A Novel Technique to Reduce Contrast Exposure During Subclavian Interventions.
Topics: Acute Kidney Injury; Aged; Angiography, Digital Subtraction; Angioplasty, Balloon; Arterial Occlusiv | 2017 |
Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease.
Topics: Acute Kidney Injury; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In | 2012 |
CT pulmonary angiography in elderly patients: outcomes in patients aged >85 years.
Topics: Age Factors; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Male; Patient Safety; Pulmo | 2013 |
Nephrotoxicity of low-osmolality versus iso-osmolality contrast agents: impact of N-acetylcysteine.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Contrast Media; Female; Fluid Therapy; Humans; Iohexol; K | 2005 |
Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.
Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Incidence; Ioxa | 2007 |
Evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in coronary angiography.
Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Ioxaglic Acid; | 2007 |