Page last updated: 2024-10-29

iodixanol and Pulmonary Embolism

iodixanol has been researched along with Pulmonary Embolism in 15 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Pulmonary Embolism: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.

Research Excerpts

ExcerptRelevanceReference
" One hundred and thirty patients (54 male; mean age, 52 years) clinically suspected of having pulmonary embolism were referred for pulmonary CT angiography and were randomly assigned to receive 80 mL of either iopamidol (370 mg of iodine per milliliter, n = 63) or iodixanol (320 mg of iodine per milliliter, n = 67) at a rate of 4 mL/sec."5.15Comparison of the effect of low- and iso-osmolar contrast agents on heart rate during chest CT angiography: results of a prospective randomized multicenter study. ( Bhalla, S; Chartrand-Lefebvre, C; Chughtai, AR; Mayo-Smith, WW; Ozkan, OS; Prenovault, J; Soto, JA; Soulez, G; Vydareny, KH; White, CS, 2011)
"To compare iomeprol 400 and iodixanol 320 in pulmonary artery MDCTA in subjects with suspected pulmonary embolism."5.14MDCT angiography for detection of pulmonary emboli: comparison between equi-iodine doses of iomeprol 400 mgI/mL and iodixanol 320 mgI/mL. ( Friedrich, K; Herold, C; Langenberger, H; Matzek, W; Plank, C; Schaefer-Prokop, C; Storto, ML; Wolf, F, 2009)
"We report a patient suspected of having pulmonary embolism, in whom a preexisting unilateral arteriovenous malformation prevented adequate evaluation of the pulmonary circulation."1.38Contralateral decubitus positioning enhances computed tomographic angiographic evaluation of pulmonary vasculature in a patient with a pulmonary arteriovenous malformation. ( Barack, BM; Berenji, GR; Santiago, S; Tafti, BA, 2012)
"In diagnosing acute pulmonary embolism (PE) in azotemic patients, scintigraphy and magnetic resonance imaging are frequently inconclusive or not available in many hospitals."1.35Minimizing contrast medium doses to diagnose pulmonary embolism with 80-kVp multidetector computed tomography in azotemic patients. ( Björk, J; Hansson, K; Holmquist, F; Nyman, U; Pasquariello, F, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (33.33)29.6817
2010's10 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jensen, J1
Lin, T1
Fishman, EK1
Johnson, PT1
Chen, YA1
Gray, BG1
Bandiera, G1
MacKinnon, D1
Deva, DP1
Holmquist, F1
Hansson, K1
Pasquariello, F1
Björk, J1
Nyman, U3
Björkdahl, P2
Chartrand-Lefebvre, C1
White, CS1
Bhalla, S1
Mayo-Smith, WW1
Prenovault, J1
Vydareny, KH1
Soto, JA1
Ozkan, OS1
Chughtai, AR1
Soulez, G1
Tafti, BA1
Berenji, GR1
Santiago, S1
Barack, BM2
Olsson, ML1
Gunnarsson, M1
Goldman, B1
Faggioni, L1
Neri, E1
Sbragia, P1
Pascale, R1
D'Errico, L1
Caramella, D1
Bartolozzi, C1
Wu, CC1
Lee, EW1
Suh, RD1
Levine, BS1
Narayan, A1
Eng, J1
Carmi, L1
McGrane, S1
Ahmed, M1
Sharrett, AR1
Streiff, M1
Coresh, J1
Powe, N1
Hong, K1
Laugharne, MJ1
Paravasthu, M1
Preston, A1
Hill, KO1
Horton, KM1
Goodman, LR1
Gulsun, M1
Nagy, P1
Washington, L1
Bédard, JP1
Blais, C1
Patenaude, YG1
Monga, E1
Langenberger, H1
Friedrich, K1
Plank, C1
Matzek, W1
Wolf, F1
Storto, ML1
Schaefer-Prokop, C1
Herold, C1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Reduction in Contrast Administration Dose in Computed Tomography Arteriograms Degrade Image Quality? A Single Institutional Review of an Ultra-low Contrast Dose Protocol[NCT02669784]34 participants (Actual)Interventional2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ascending Sinotubular Junction Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. Measurement was taken at the ascending aorta near the sinotubular junction. (NCT02669784)
Timeframe: At 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)246.4
Contrast (Omnipaque) Low Dose (50mL)287.5

Burfication Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the distal abdominal aorta prior to the bifurcation. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)336.2
Contrast (Omnipaque) Low Dose (50mL)321.2

Celiac Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the proximal abdominal aorta at the level of the celiac axis. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)243.8
Contrast (Omnipaque) Low Dose (50mL)329.5

CTA Vessel Opacification Grading 1

"5 Point Grading Scale was used to determine CTA Vessel Opacification by a Board Certified Radiologist.~Poor opacification with no difference in attenuation of the lumen compared to the wall of the vessel. Non diagnostic.~Decreased opacification. Little to no difference in attenuation between the lumen and the wall. Non diagnostic.~Moderate opacification of the lumen of the vessel. Diagnostic study.~Good opacification of the lumen of the vessel.~Excellent opacification of the lumen of the vessel with distinct difference in attenuation of the wall and lumen of the vessel." (NCT02669784)
Timeframe: 30 days

Interventionscore on a scale (Mean)
Contrast (Omnipaque) Low Dose (40mL)4
Contrast (Omnipaque) Low Dose (50mL)4.3

CTA Vessel Opacification Grading 2

"5 Point Grading Scale was used to determine CTA Vessel Opacification by a second Board Certified Radiologist.~Poor opacification with no difference in attenuation of the lumen compared to the wall of the vessel. Non diagnostic.~Decreased opacification. Little to no difference in attenuation between the lumen and the wall. Non diagnostic.~Moderate opacification of the lumen of the vessel. Diagnostic~Good opacification of the lumen of the vessel.~Excellent opacification of the lumen of the vessel with distinct difference in attenuation of the wall and lumen of the vessel." (NCT02669784)
Timeframe: 30 days

Interventionscore on a scale (Mean)
Contrast (Omnipaque) Low Dose (40mL)4.2
Contrast (Omnipaque) Low Dose (50mL)4.4

Descending Thoracic Aorta Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the distal abdominal aorta prior to the bifurcation. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)261.9
Contrast (Omnipaque) Low Dose (50mL)312.8

Left Common Femoral Artery Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the right common femoral artery. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (50mL)309.5

Right Common Femoral Artery Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the right common femoral artery. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (50mL)314.5

Trials

3 trials available for iodixanol and Pulmonary Embolism

ArticleYear
Comparison of the effect of low- and iso-osmolar contrast agents on heart rate during chest CT angiography: results of a prospective randomized multicenter study.
    Radiology, 2011, Volume: 258, Issue:3

    Topics: Chi-Square Distribution; Contrast Media; Coronary Angiography; Double-Blind Method; Electrocardiogra

2011
Pulmonary embolism: prospective comparison of iso-osmolar and low-osmolarity nonionic contrast agents for contrast enhancement at CT angiography.
    Radiology, 2005, Volume: 234, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Chi-Square Distribution; Contrast Media; Double-Blind M

2005
MDCT angiography for detection of pulmonary emboli: comparison between equi-iodine doses of iomeprol 400 mgI/mL and iodixanol 320 mgI/mL.
    European journal of radiology, 2009, Volume: 70, Issue:3

    Topics: Aged; Angiography; Contrast Media; Dose-Response Relationship, Drug; Female; Humans; Iopamidol; Male

2009

Other Studies

12 other studies available for iodixanol and Pulmonary Embolism

ArticleYear
Pulmonary CTA in sickle cell patients: quantitative assessment of enhancement quality.
    Emergency radiology, 2017, Volume: 24, Issue:6

    Topics: Adult; Anemia, Sickle Cell; Case-Control Studies; Computed Tomography Angiography; Contrast Media; F

2017
Variation in the utilization and positivity rates of CT pulmonary angiography among emergency physicians at a tertiary academic emergency department.
    Emergency radiology, 2015, Volume: 22, Issue:3

    Topics: Adult; Aged; Angiography; Contrast Media; Cross-Sectional Studies; Emergency Service, Hospital; Fema

2015
Minimizing contrast medium doses to diagnose pulmonary embolism with 80-kVp multidetector computed tomography in azotemic patients.
    Acta radiologica (Stockholm, Sweden : 1987), 2009, Volume: 50, Issue:2

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Azotemia; Contrast Media; Female; Humans; Linear Mode

2009
Using 100- instead of 120-kVp computed tomography to diagnose pulmonary embolism almost halves the radiation dose with preserved diagnostic quality.
    Acta radiologica (Stockholm, Sweden : 1987), 2010, Volume: 51, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Male; Middle Aged; Phantoms, Imaging

2010
Contralateral decubitus positioning enhances computed tomographic angiographic evaluation of pulmonary vasculature in a patient with a pulmonary arteriovenous malformation.
    Journal of thoracic imaging, 2012, Volume: 27, Issue:6

    Topics: Aged; Arteriovenous Malformations; Contrast Media; Diagnosis, Differential; Humans; Male; Patient Po

2012
Low-dose radiation with 80-kVp computed tomography to diagnose pulmonary embolism: a feasibility study.
    Acta radiologica (Stockholm, Sweden : 1987), 2012, Nov-01, Volume: 53, Issue:9

    Topics: Contrast Media; Feasibility Studies; Humans; Monte Carlo Method; Phantoms, Imaging; Pulmonary Emboli

2012
80-kV pulmonary CT angiography with 40 mL of iodinated contrast material in lean patients: comparison of vascular enhancement with iodixanol (320 mg I/mL)and iomeprol (400 mg I/mL).
    AJR. American journal of roentgenology, 2012, Volume: 199, Issue:6

    Topics: Aged; Aged, 80 and over; Angiography; Body Mass Index; Carcinoma, Non-Small-Cell Lung; Contrast Medi

2012
Pulmonary 64-MDCT angiography with 30 mL of IV contrast material: vascular enhancement and image quality.
    AJR. American journal of roentgenology, 2012, Volume: 199, Issue:6

    Topics: Aged; Algorithms; Angiography; Contrast Media; Female; Humans; Male; Pulmonary Embolism; Radiographi

2012
Iliac vein compression as risk factor for left- versus right-sided deep venous thrombosis: case-control study.
    Radiology, 2012, Volume: 265, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chi-Square Distribution; Child; Co

2012
CT pulmonary angiography in elderly patients: outcomes in patients aged >85 years.
    Clinical radiology, 2013, Volume: 68, Issue:5

    Topics: Age Factors; Aged, 80 and over; Contrast Media; Female; Humans; Iohexol; Male; Patient Safety; Pulmo

2013
How we do it: pulmonary embolism.
    Critical reviews in computed tomography, 2002, Volume: 43, Issue:2

    Topics: Contrast Media; Humans; Pulmonary Embolism; Tomography Scanners, X-Ray Computed; Tomography, X-Ray C

2002
CT of deep venous thrombosis and pulmonary embolus: does iso-osmolar contrast agent improve vascular opacification?
    Radiology, 2005, Volume: 234, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Angiography; Contrast Media; Female; Humans; Image Processing, Compu

2005