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iodixanol and Necrosis

iodixanol has been researched along with Necrosis in 4 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"Apoptosis plus an antiproliferative effect of iodixanol without cell necrosis contribute to the renal tubular toxicity of iodixanol."3.75Iodixanol induces apoptotic and antiproliferative effects but no necrotic cell death in renal proximal tubular cells in vitro. ( Heckmann, M; Heinrich, MC; Kuefner, MA; Scheer, M; Uder, M, 2009)
"Gadobutrol caused extensive tubular necrosis and moderate glomerular necrosis; gadodiamide and iopromide, minimal to mild tubular necrosis; and iodixanol, no necrosis."3.74Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: arteriography in ischemic porcine kidneys. ( Almén, T; Björk, J; Chai, CM; Doughty, R; Elmståhl, B; Golman, K; Grant, D; Leander, P; Nyman, U; Pehrson, R, 2008)
"More necrosis was present after incubation with iohexol and iopamidol than after incubation with equal concentrations of iodixanol."1.40Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury. ( Cafiero, C; Gesualdo, L; Grandaliano, G; Montemurno, E; Netti, GS; Prattichizzo, C; Ranieri, E; Rascio, F; Simone, S; Stallone, G, 2014)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (75.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Netti, GS1
Prattichizzo, C1
Montemurno, E1
Simone, S1
Cafiero, C1
Rascio, F1
Stallone, G1
Ranieri, E1
Grandaliano, G1
Gesualdo, L1
Heinrich, MC1
Scheer, M1
Heckmann, M1
Kuefner, MA1
Uder, M1
Elmståhl, B1
Nyman, U1
Leander, P1
Golman, K1
Chai, CM1
Grant, D1
Doughty, R1
Pehrson, R1
Björk, J1
Almén, T1
Main, ML1
Magalski, A1
Chee, NK1
Coen, MM1
Skolnick, DG1
Good, TH1

Other Studies

4 other studies available for iodixanol and Necrosis

ArticleYear
Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury.
    Free radical biology & medicine, 2014, Volume: 68

    Topics: Acute Kidney Injury; Apoptosis; Contrast Media; Humans; Iohexol; Iopamidol; Kidney; NADP; NADPH Oxid

2014
Iodixanol induces apoptotic and antiproliferative effects but no necrotic cell death in renal proximal tubular cells in vitro.
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2009, Volume: 181, Issue:4

    Topics: Apoptosis; Cell Line; Cell Proliferation; Contrast Media; Dose-Response Relationship, Drug; Humans;

2009
Iodixanol 320 results in better renal tolerance and radiodensity than do gadolinium-based contrast media: arteriography in ischemic porcine kidneys.
    Radiology, 2008, Volume: 247, Issue:1

    Topics: Animals; Contrast Media; Gadolinium; Gadolinium DTPA; Ischemia; Kidney; Male; Necrosis; Organometall

2008
Full-motion pulse inversion power Doppler contrast echocardiography differentiates stunning from necrosis and predicts recovery of left ventricular function after acute myocardial infarction.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: Aged; Albumins; Angioplasty, Balloon, Coronary; Coronary Angiography; Diagnosis, Differential; Echoc

2001