Page last updated: 2024-10-29

iodixanol and Myocardial Infarction

iodixanol has been researched along with Myocardial Infarction in 26 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Myocardial Infarction: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).

Research Excerpts

ExcerptRelevanceReference
"To evaluate iodixanol-associated acute kidney injury (AKI) and prognosis in patients undergoing elective percutaneous coronary intervention (PCI)."8.31Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study. ( Azzalini, L; Chen, Z; Huang, L; Jiang, Y; Mao, Q; Xiang, L; Zhao, N; Zhao, X; Zhou, D, 2023)
"To evaluate iodixanol-associated acute kidney injury (AKI) and prognosis in patients undergoing elective percutaneous coronary intervention (PCI)."4.31Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study. ( Azzalini, L; Chen, Z; Huang, L; Jiang, Y; Mao, Q; Xiang, L; Zhao, N; Zhao, X; Zhou, D, 2023)
"Hyperhomocysteinemia induces oxidative stress and endothelial dysfunction, which share the proposed pathophysiologic mechanisms of contrast-induced nephropathy (CIN)."3.77Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention. ( Choi, D; Choi, KH; Han, SH; Hong, MK; Jang, Y; Kang, SW; Kim, BK; Kim, JS; Kim, SJ; Ko, YG; Yoo, TH, 2011)
" The secondary endpoints are absolute and relative increases in sCr of at least 50%, thrombolysis in myocardial infarction (TIMI) perfusion grade, and major adverse cardiac events at 1, 6, and 12 months."2.75The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study. ( Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C, 2010)
"The relative incidence of long-term adverse effects between low-osmolar contrast media (LOCM) and iso-osmolar contrast media (IOCM) after coronary angiography is still unclear."1.43Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography. ( Chang, D; Ju, S; Lu, CQ; Tang, A; Wang, YC; Zhang, SJ, 2016)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.85)18.2507
2000's11 (42.31)29.6817
2010's13 (50.00)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Chen, Z1
Mao, Q1
Xiang, L1
Zhou, D1
Jiang, Y1
Zhao, N1
Huang, L1
Azzalini, L1
Zhao, X1
Ustunkaya, T1
Desjardins, B1
Liu, B1
Zahid, S1
Park, J1
Saju, N1
Trayanova, N1
Zimmerman, SL1
Marchlinski, FE1
Nazarian, S2
Limbruno, U3
Picchi, A3
Micheli, A1
Calabria, P1
Cortese, B1
Brizi, G1
Severi, S1
De Caterina, R1
Jurado-Román, A1
Hernández-Hernández, F1
García-Tejada, J1
Granda-Nistal, C1
Molina, J1
Velázquez, M1
Albarrán, A1
Tascón, J1
Budoff, MJ1
Bloom, SA1
Chow, BJ1
Chandler, AB1
Cole, JH1
Giustino, G1
Baber, U1
Mastoris, I1
Vlachojannis, GJ1
Yu, J1
Teirstein, PS1
Downey, WE1
Batchelor, WB1
Casterella, PJ1
Nikolsky, E1
Wong, SC1
Theodoropoulos, KN1
Dangas, GD1
Mehran, R1
Wang, YC1
Tang, A1
Chang, D1
Lu, CQ1
Zhang, SJ1
Ju, S1
Cury, RC2
Nieman, K2
Shapiro, MD2
Butler, J1
Nomura, CH2
Ferencik, M2
Hoffmann, U2
Abbara, S2
Jassal, DS1
Yasuda, T1
Gold, HK2
Jang, IK2
Brady, TJ2
Larose, E1
Côté, J1
Rodés-Cabau, J1
Noël, B1
Barbeau, G1
Bordeleau, E1
Miró, S1
Brochu, B1
Delarochellière, R1
Bertrand, OF1
Steppich, BA1
Kaufmann, J1
Sepp, D1
Kunert, K1
Rutz, T1
Stratz, C1
Ott, I1
Loewe, C1
Desai, MY1
Flamm, SD1
Chang, HJ1
George, RT3
Schuleri, KH3
Evers, K1
Kitagawa, K1
Lima, JA3
Lardo, AC3
Bolognese, L2
Falsini, G2
Grotti, S2
Liistro, F2
Carrera, A2
Angioli, P2
Ducci, K2
Pierli, C2
Wi, J1
Ko, YG2
Kim, JS2
Kim, BK2
Choi, D2
Ha, JW1
Hong, MK2
Jang, Y2
Kim, SJ1
Han, SH1
Kang, SW1
Choi, KH1
Yoo, TH1
Schwenke, C1
Centola, M1
Choi, SH1
Evers, KS1
Dawoud, F1
Alam, SR1
Shah, AS1
Richards, J1
Lang, NN1
Barnes, G1
Joshi, N1
MacGillivray, T1
McKillop, G1
Mirsadraee, S1
Payne, J1
Fox, KA1
Henriksen, P1
Newby, DE1
Semple, SI1
Sosnovik, DE1
Nahrendorf, M1
Cordeiro, MA1
Silva, C1
Amado, LC1
Saliaris, AP1
Fernandes, VR1
Zviman, M1
Halperin, HR1
Wu, KC1
Hare, JM1
Choi, CU1
Rha, SW1
Suh, SY1
Kim, JW1
Kim, EJ1
Park, CG1
Seo, HS1
Oh, DJ1
Harnish, P1
Fountaine, H1
Bertrand, ME1
Esplugas, E1
Piessens, J1
Rasch, W1
Main, ML1
Magalski, A1
Chee, NK1
Coen, MM1
Skolnick, DG1
Good, TH1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Contrast-inDuced nephRotoxicity as Assessed by the Cystatin-modified KIdney Load-to-DAmage RElationship[NCT01908309]Early Phase 1150 participants (Actual)Interventional2013-04-30Completed
Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.[NCT05147831]300 participants (Anticipated)Interventional2021-11-30Recruiting
Acute Chest Pain Imaging in Emergency Department With Combined Approach of Coronary CT Angiography and CT Myocardial Perfusion[NCT02538861]250 participants (Actual)Observational2015-09-30Completed
The Contrast Media and Nephrotoxicity Following Coronary Revascularization by Primary Angioplasty for Acute Myocardial Infarction. The CONTRAST-AMI Study.[NCT00827788]Phase 4432 participants (Anticipated)Interventional2008-12-31Completed
Department of Geriatrics[NCT02575092]Phase 2/Phase 34,000 participants (Actual)Interventional2015-11-01Completed
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention[NCT03266458]210 participants (Anticipated)Observational [Patient Registry]2018-01-01Not yet recruiting
Periprocedural Administration of Folic Acid for Prevention of Contrast Induced Nephropathy in Patients Undergoing Coronary CTA/Angiography/Angioplasty[NCT02444013]Phase 4400 participants (Anticipated)Interventional2015-05-31Recruiting
High Dose Atorvastatin Raises Threshold of Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention[NCT04375787]Phase 4200 participants (Actual)Interventional2020-03-15Completed
Evaluation of the Effect of Dapagliflozin on Cardiac Remodeling in Post Myocardial Infarction Patients[NCT05335629]60 participants (Anticipated)Interventional2022-09-01Recruiting
Pathogenesis of Acute Stress Induced (Tako-tsubo) Cardiomyopathy: Energy Shut-Down or Intense Inflammation? The TERRIFIC Study[NCT02897739]77 participants (Actual)Observational [Patient Registry]2015-08-31Completed
Ferumoxytol for Magnetic Resonance Imaging of Myocardial Infarction[NCT01323296]15 participants (Actual)Interventional2010-11-30Completed
Microvascular Obstruction by Contrast-enhanced MRI Following Percutaneous Coronary Interventions[NCT00692991]144 participants (Actual)Observational1999-10-31Completed
Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging[NCT00857792]120 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ability to Detect Stress-induced Myocardial Perfusion Abnormalities by Analysis of MDCT Images Confirmed by Coronary Angiography and/or SPECT.

(NCT00857792)
Timeframe: 3 months

Intervention% accurately detected perfusion defects (Number)
Open Label78

Trials

6 trials available for iodixanol and Myocardial Infarction

ArticleYear
Refining the assessment of contrast-induced acute kidney injury: the load-to-damage relationship.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2014, Volume: 15, Issue:7

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Dose-Response Relations

2014
Role of hydration in contrast-induced nephropathy in patients who underwent primary percutaneous coronary intervention.
    The American journal of cardiology, 2015, May-01, Volume: 115, Issue:9

    Topics: Aged; Contrast Media; Creatinine; Female; Fluid Therapy; Humans; Intraoperative Care; Isotonic Solut

2015
One-year results of the ICON (Ionic versus non-ionic Contrast to Obviate worsening Nephropathy after angioplasty in chronic renal failure patients) Study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 87, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Corona

2016
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Influence of a nonionic, iso-osmolar contrast medium (iodixanol) versus an ionic, low-osmolar contrast medium (ioxaglate) on major adverse cardiac events in patients undergoing percutaneous transluminal coronary angioplasty: A multicenter, randomized, dou
    Circulation, 2000, Jan-18, Volume: 101, Issue:2

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Artery Bypass; Double-Blind Method; F

2000

Other Studies

20 other studies available for iodixanol and Myocardial Infarction

ArticleYear
Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study.
    European radiology, 2023, Volume: 33, Issue:12

    Topics: Acute Kidney Injury; Aged; Contrast Media; Humans; Myocardial Infarction; Percutaneous Coronary Inte

2023
Association of regional myocardial conduction velocity with the distribution of hypoattenuation on contrast-enhanced perfusion computed tomography in patients with postinfarct ventricular tachycardia.
    Heart rhythm, 2019, Volume: 16, Issue:4

    Topics: Contrast Media; Electrocardiography; Epicardial Mapping; Heart Conduction System; Humans; Imaging, T

2019
Coronary computed tomography angiography predicts subsequent cardiac outcome events: results of the Visipaque CCTA registry study.
    Coronary artery disease, 2015, Volume: 26, Issue:4

    Topics: Contrast Media; Coronary Angiography; Coronary Artery Disease; Coronary Stenosis; False Negative Rea

2015
Long-Term Adverse Effects of Low-Osmolar Compared With Iso-Osmolar Contrast Media After Coronary Angiography.
    The American journal of cardiology, 2016, Oct-01, Volume: 118, Issue:7

    Topics: Aged; Cause of Death; China; Contrast Media; Coronary Angiography; Female; Heart Failure; Humans; In

2016
Comprehensive assessment of myocardial perfusion defects, regional wall motion, and left ventricular function by using 64-section multidetector CT.
    Radiology, 2008, Volume: 248, Issue:2

    Topics: Biomarkers; Chi-Square Distribution; Contrast Media; Echocardiography; Female; Humans; Male; Middle

2008
Contrast-enhanced cardiovascular magnetic resonance in the hyperacute phase of ST-elevation myocardial infarction.
    The international journal of cardiovascular imaging, 2009, Volume: 25, Issue:5

    Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Case-Control Studies; Contrast Media; Coronary Angiogra

2009
Increased circulating placental growth factor during percutaneous coronary intervention is associated with applied radiocontrast agent.
    Coronary artery disease, 2009, Volume: 20, Issue:2

    Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Anticoagulants; Biomarkers; Case-Control Studies; C

2009
[Cardiac imaging].
    Der Radiologe, 2009, Volume: 49, Issue:4

    Topics: Biomarkers; Chi-Square Distribution; Contrast Media; Echocardiography; Female; Humans; Male; Middle

2009
End of the road for delayed hyperenhancement cardiac magnetic resonance?
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:4

    Topics: Algorithms; Animals; Contrast Media; Electrocardiography; Humans; Magnetic Resonance Imaging; Microv

2009
Prospective electrocardiogram-gated delayed enhanced multidetector computed tomography accurately quantifies infarct size and reduces radiation exposure.
    JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:4

    Topics: Algorithms; Animals; Contrast Media; Disease Models, Animal; Electrocardiography; Microvessels; Myoc

2009
Impact of contrast-induced acute kidney injury with transient or persistent renal dysfunction on long-term outcomes of patients with acute myocardial infarction undergoing percutaneous coronary intervention.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:21

    Topics: Acute Kidney Injury; Adult; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Disease Progressio

2011
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2011, Oct-15, Volume: 108, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Follow-Up Studie

2011
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2011, Oct-15, Volume: 108, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Follow-Up Studie

2011
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2011, Oct-15, Volume: 108, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Follow-Up Studie

2011
Relation of homocysteinemia to contrast-induced nephropathy in patients undergoing percutaneous coronary intervention.
    The American journal of cardiology, 2011, Oct-15, Volume: 108, Issue:8

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Female; Follow-Up Studie

2011
CT for evaluation of myocardial cell therapy in heart failure: a comparison with CMR imaging.
    JACC. Cardiovascular imaging, 2011, Volume: 4, Issue:12

    Topics: Animals; Contrast Media; Disease Models, Animal; Female; Gadolinium DTPA; Heart Failure; Linear Mode

2011
Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Dextrans; Female; Humans; Infusio

2012
Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Dextrans; Female; Humans; Infusio

2012
Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Dextrans; Female; Humans; Infusio

2012
Ultrasmall superparamagnetic particles of iron oxide in patients with acute myocardial infarction: early clinical experience.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Angioplasty, Balloon, Coronary; Dextrans; Female; Humans; Infusio

2012
Cells and iron oxide nanoparticles on the move: magnetic resonance imaging of monocyte homing and myocardial inflammation in patients with ST-elevation myocardial infarction.
    Circulation. Cardiovascular imaging, 2012, Sep-01, Volume: 5, Issue:5

    Topics: Dextrans; Female; Humans; Magnetic Resonance Imaging; Magnetite Nanoparticles; Male; Myocardial Infa

2012
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar.
    Circulation, 2006, Jan-24, Volume: 113, Issue:3

    Topics: Acute Disease; Animals; Cell Death; Chronic Disease; Cicatrix; Contrast Media; Coronary Angiography;

2006
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar.
    Circulation, 2006, Jan-24, Volume: 113, Issue:3

    Topics: Acute Disease; Animals; Cell Death; Chronic Disease; Cicatrix; Contrast Media; Coronary Angiography;

2006
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar.
    Circulation, 2006, Jan-24, Volume: 113, Issue:3

    Topics: Acute Disease; Animals; Cell Death; Chronic Disease; Cicatrix; Contrast Media; Coronary Angiography;

2006
Contrast-enhanced multidetector computed tomography viability imaging after myocardial infarction: characterization of myocyte death, microvascular obstruction, and chronic scar.
    Circulation, 2006, Jan-24, Volume: 113, Issue:3

    Topics: Acute Disease; Animals; Cell Death; Chronic Disease; Cicatrix; Contrast Media; Coronary Angiography;

2006
Extensive exfoliative dermatitis induced by non-ionic contrast medium Iodixanol (Visipaque) used during percutaneous coronary intervention.
    International journal of cardiology, 2008, Feb-29, Volume: 124, Issue:2

    Topics: Angioplasty, Balloon, Coronary; Chest Pain; Contrast Media; Coronary Angiography; Dermatitis, Exfoli

2008
Reperfused myocardial infarction: contrast-enhanced 64-Section CT in comparison to MR imaging.
    Radiology, 2008, Volume: 247, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Coronary Circulation; Female; Gadolinium DTPA; Heart

2008
Iodixanol and the heart.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Adult; Aged; Aged, 80 and over; Angiocardiography; Contrast Media; Electrocardiography; Female; Hear

1996
Full-motion pulse inversion power Doppler contrast echocardiography differentiates stunning from necrosis and predicts recovery of left ventricular function after acute myocardial infarction.
    Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5

    Topics: Aged; Albumins; Angioplasty, Balloon, Coronary; Coronary Angiography; Diagnosis, Differential; Echoc

2001