Page last updated: 2024-10-29

iodixanol and Delayed Hypersensitivity

iodixanol has been researched along with Delayed Hypersensitivity in 11 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Research Excerpts

ExcerptRelevanceReference
" This presented a management challenge as the patient had experienced 2 episodes of delayed anaphylaxis to Omnipaque (iohexol) RCM, and based on a literature review, there was no known or established precedent on a safe procedure in these situations."7.88Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol. ( Cohen, B; Edelman, D; Garg, K; Jariwala, S; Soffer, G; Toh, J, 2018)
" This presented a management challenge as the patient had experienced 2 episodes of delayed anaphylaxis to Omnipaque (iohexol) RCM, and based on a literature review, there was no known or established precedent on a safe procedure in these situations."3.88Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol. ( Cohen, B; Edelman, D; Garg, K; Jariwala, S; Soffer, G; Toh, J, 2018)
"Cross-reactivity was assessed by skin testing and measurement of T-cell activation (CD69 upregulation) and proliferation ((3)H-thymidine uptake, 5,6-carboxyfluorescein diacetate succinimidyl ester staining) of PBMCs, T-cell lines, and T-cell clones of 2 patients with delayed hypersensitivity reactions to iohexol and iomeprol, respectively."3.74Cross-reactivity patterns of T cells specific for iodinated contrast media. ( Beeler, A; Bircher, AJ; Britschgi, M; Christiansen, C; Gerber, BO; Kanny, G; Keller, M; Lerch, M; Luethi, M; Pichler, WJ; Schmid, DA; Tache, V, 2007)
"Trigonelline inhibit iodixanol-induced MC-related pseudo-allergic reactions in vitro and in vivo."1.72Iodixanol activation of mast cells: Implications in the pathogenesis of iodixanol-induced delayed cutaneous adverse reactions. ( Chen, L; Hao, G; Hu, C; Hu, S; Yang, S; Zou, W, 2022)
"Iodixanol was a significant risk factor for delayed HSR (OR 1."1.51Immediate and delayed hypersensitivity after intra-arterial injection of iodinated contrast media: a prospective study in patients with coronary angiography. ( Cho, SH; Han, JK; Kang, HR; Kim, GW; Kim, HS; Lee, SY; Sohn, KH, 2019)
"Iodixanol is a non-ionic contrast medium for general vascular use."1.46Delayed genital blisters following iodixanol administration. ( Xie, H; Yang, XL; Yuan, HL; Yuan, W; Zhang, W, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (36.36)29.6817
2010's6 (54.55)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Zou, W1
Yang, S1
Chen, L1
Hu, S1
Hao, G1
Hu, C1
Zhang, W1
Yuan, W1
Yuan, HL1
Yang, XL1
Xie, H1
Soffer, G1
Cohen, B1
Toh, J1
Edelman, D1
Garg, K1
Jariwala, S1
Sohn, KH1
Kim, GW1
Lee, SY1
Kim, HS1
Cho, SH1
Han, JK1
Kang, HR1
Bircher, AJ2
Brockow, K1
Grosber, M1
Hofmeier, KS1
Corbaux, C1
Seneschal, J1
Taïeb, A1
Cornelis, F1
Martinet, J1
Milpied, B1
Chuang, FR1
Chen, TC1
Wang, IK1
Chuang, CH1
Chang, HW1
Ting-Yu Chiou, T1
Cheng, YF1
Lee, WC1
Chen, WC1
Yang, KD1
Lee, CH1
Antunez, C1
Barbaud, A1
Gomez, E1
Audonnet, S1
Lopez, S1
Guéant-Rodriguez, RM1
Aimone-Gastin, I1
Gomez, F1
Blanca, M1
Guéant, JL1
Sánchez-Pérez, J1
F-Villalta, MG1
Ruíz, SA1
García Diez, A1
Lerch, M1
Keller, M1
Britschgi, M1
Kanny, G1
Tache, V1
Schmid, DA1
Beeler, A1
Gerber, BO1
Luethi, M1
Christiansen, C1
Pichler, WJ1
Salerno, S1
Cannizzaro, F1
Lo Casto, A1
Speciale, R1

Trials

1 trial available for iodixanol and Delayed Hypersensitivity

ArticleYear
Comparison of iodixanol and iohexol in patients undergoing intravenous pyelography: a prospective controlled study.
    Renal failure, 2009, Volume: 31, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Contrast Media; Creatinine; Cytokines; Double-Blind Method; Drug E

2009

Other Studies

10 other studies available for iodixanol and Delayed Hypersensitivity

ArticleYear
Iodixanol activation of mast cells: Implications in the pathogenesis of iodixanol-induced delayed cutaneous adverse reactions.
    Toxicology, 2022, 01-15, Volume: 465

    Topics: Alkaloids; Animals; Anti-Allergic Agents; Calcium; Cell Degranulation; Cell Line; Contrast Media; Cy

2022
Delayed genital blisters following iodixanol administration.
    Clinical toxicology (Philadelphia, Pa.), 2017, Volume: 55, Issue:8

    Topics: Angiography, Digital Subtraction; Anti-Allergic Agents; Blister; Contrast Media; Drug Eruptions; Hum

2017
Successful Graded Dose Challenge to Iodixanol Radiocontrast Media in a Patient With Delayed Anaphylaxis to Iohexol.
    Vascular and endovascular surgery, 2018, Volume: 52, Issue:1

    Topics: Aged, 80 and over; Anaphylaxis; Angiography; Anti-Allergic Agents; Contrast Media; Drug Administrati

2018
Immediate and delayed hypersensitivity after intra-arterial injection of iodinated contrast media: a prospective study in patients with coronary angiography.
    European radiology, 2019, Volume: 29, Issue:10

    Topics: Contrast Media; Coronary Angiography; Drug Hypersensitivity; Female; Humans; Hypersensitivity, Delay

2019
Late elicitation of maculopapular exanthemas to iodinated contrast media after first exposure.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2013, Volume: 111, Issue:6

    Topics: Aged; Aged, 80 and over; Contrast Media; Drug Hypersensitivity; Exanthema; Female; Humans; Hypersens

2013
Delayed cutaneous hypersensitivity reactions to iodinated contrast media.
    European journal of dermatology : EJD, 2017, 04-01, Volume: 27, Issue:2

    Topics: Aged; Contrast Media; Cross Reactions; Delayed Diagnosis; Drug Hypersensitivity; Humans; Hypersensit

2017
Recognition of iodixanol by dendritic cells increases the cellular response in delayed allergic reactions to contrast media.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2011, Volume: 41, Issue:5

    Topics: Aged, 80 and over; Cell Proliferation; Contrast Media; Cytokines; Dendritic Cells; Humans; Hypersens

2011
Delayed hypersensitivity reaction to the non-ionic X-ray contrast medium Visipaque (iodixanol).
    Contact dermatitis, 2003, Volume: 48, Issue:3

    Topics: Aged; Allergens; Cerebral Arterial Diseases; Contrast Media; Diagnosis, Differential; Drug Hypersens

2003
Cross-reactivity patterns of T cells specific for iodinated contrast media.
    The Journal of allergy and clinical immunology, 2007, Volume: 119, Issue:6

    Topics: Aged; Cell Line; Clone Cells; Contrast Media; Female; Humans; Hypersensitivity, Delayed; Iohexol; Io

2007
Late allergic reaction following sialography.
    Dento maxillo facial radiology, 2002, Volume: 31, Issue:2

    Topics: Adult; Contrast Media; Drug Hypersensitivity; Edema; Female; Humans; Hypersensitivity, Delayed; Orop

2002