Page last updated: 2024-10-29

iodixanol and Coronary Disease

iodixanol has been researched along with Coronary Disease in 36 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Renal Insufficiency Following Radiocontrast Exposure demonstrates a homogeneously low rate of CIN after exposure to nonionic, iso-osmolar iodixanol regardless of the use of either bicarbonate sodium or sodium chloride solution for volume supplementation."9.13Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. ( Adolph, E; Chatterjee, T; Holdt-Lehmann, B; Ince, H; Koerber, T; Nienaber, CA; Paschka, S; Prott, A; Schneider, H; Schuff-Werner, P; Steiner, M, 2008)
" We investigated to determine whether simvastatin pretreatment reduces the risk of contrast-induced nephropathy in a high-risk population of patients with renal insufficiency undergoing coronary angiography."9.13Prevention of radiocontrast medium-induced nephropathy using short-term high-dose simvastatin in patients with renal insufficiency undergoing coronary angiography (PROMISS) trial--a randomized controlled study. ( Chae, IH; Cho, YS; Choi, DJ; Choi, YS; Chung, WY; Jo, SH; Kang, HJ; Kim, HS; Kim, YJ; Koo, BK; Oh, BH; Park, JS; Park, YB; Sohn, DW; Youn, TJ, 2008)
"Renal Insufficiency Following Radiocontrast Exposure demonstrates a homogeneously low rate of CIN after exposure to nonionic, iso-osmolar iodixanol regardless of the use of either bicarbonate sodium or sodium chloride solution for volume supplementation."5.13Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy. ( Adolph, E; Chatterjee, T; Holdt-Lehmann, B; Ince, H; Koerber, T; Nienaber, CA; Paschka, S; Prott, A; Schneider, H; Schuff-Werner, P; Steiner, M, 2008)
" We investigated to determine whether simvastatin pretreatment reduces the risk of contrast-induced nephropathy in a high-risk population of patients with renal insufficiency undergoing coronary angiography."5.13Prevention of radiocontrast medium-induced nephropathy using short-term high-dose simvastatin in patients with renal insufficiency undergoing coronary angiography (PROMISS) trial--a randomized controlled study. ( Chae, IH; Cho, YS; Choi, DJ; Choi, YS; Chung, WY; Jo, SH; Kang, HJ; Kim, HS; Kim, YJ; Koo, BK; Oh, BH; Park, JS; Park, YB; Sohn, DW; Youn, TJ, 2008)
"Iodixanol is a new nonionic, dimeric contrast medium."2.67Iodixanol in cardioangiography in patients with coronary artery disease. Tolerability, cardiac and renal effects. ( Berg, KJ; Brodahl, U; Endresen, K; Kløw, NE; Kristoffersen, DT; Laake, B; Levorstad, K; Lundby, B; Simonsen, S; Tofte, AJ, 1993)
" Seventy patients matched for BMI who had previously undergone routine coronary CT angiography with a fixed contrast material dosage of 80 mL at 5 mL/s served as the reference group."1.35Low-dose coronary CT angiography with prospective ECG triggering: validation of a contrast material protocol adapted to body mass index. ( Burger, IA; Burkhard, N; Gaemperli, O; Herzog, BA; Husmann, L; Kaufmann, PA; Valenta, I, 2009)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (19.44)18.2507
2000's25 (69.44)29.6817
2010's4 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di Cesare, E1
Gennarelli, A1
Di Sibio, A1
Felli, V1
Perri, M1
Splendiani, A1
Gravina, GL1
Barile, A1
Masciocchi, C1
Rudnick, MR1
Davidson, C1
Laskey, W1
Stafford, JL1
Sherwin, PF1
Adolph, E1
Holdt-Lehmann, B1
Chatterjee, T1
Paschka, S1
Prott, A1
Schneider, H1
Koerber, T1
Ince, H1
Steiner, M1
Schuff-Werner, P1
Nienaber, CA1
Heng, AE1
Cellarier, E1
Aublet-Cuvelier, B1
Decalf, V1
Motreff, P1
Marcaggi, X1
Deteix, P1
Souweine, B1
Tatsugami, F1
Husmann, L4
Herzog, BA2
Burkhard, N2
Valenta, I3
Gaemperli, O3
Kaufmann, PA3
Burger, IA1
Hernández, F1
Mora, L1
García-Tejada, J1
Velázquez, M1
Gómez-Blázquez, I1
Bastante, T1
Albarrán, A1
Andreu, J1
Tascón, J1
Leipsic, J2
Labounty, TM2
Heilbron, B2
Min, JK2
Mancini, GB2
Lin, FY2
Taylor, C2
Dunning, A2
Earls, JP3
Fedele, S1
Biondi-Zoccai, G1
Kwiatkowski, P1
Di Vito, L1
Occhipinti, M1
Cremonesi, A1
Albertucci, M1
Materia, L1
Paoletti, G1
Prati, F1
Cademartiri, F2
Nieman, K1
van der Lugt, A1
Raaijmakers, RH1
Mollet, N1
Pattynama, PM1
de Feyter, PJ1
Krestin, GP2
Dewey, M1
Müller, M1
Teige, F1
Hamm, B1
Bae, KT1
Mollet, NR1
Runza, G1
Belgrano, M1
Malagutti, P1
Meijboom, BW1
Midiri, M1
Feyter, PJ1
Alkadhi, H3
Bettex, D1
Wildermuth, S1
Baumert, B1
Plass, A1
Grunenfelder, J1
Desbiolles, L2
Marincek, B2
Boehm, T1
Henneman, MM1
Bax, JJ1
Schuijf, JD1
van der Wall, EE1
Valente, S1
Lazzeri, C1
Giglioli, C1
Margheri, M1
Comeglio, M1
Nicolaci, L1
Chechi, T1
Gensini, GF1
Frauenfelder, T1
Boutsianis, E1
Schertler, T1
Leschka, S2
Poulikakos, D1
Schmid, I1
Didier, D1
Pfammatter, T1
Garachemani, A1
Fleisch, M1
Kirchin, MA1
Meier, B1
Deray, G1
Persson, P1
Liss, P1
Hansell, P1
Shapiro, MD1
Pena, AJ1
Nichols, JH1
Worrell, S1
Bamberg, F1
Dannemann, N1
Abbara, S1
Cury, RC1
Brady, TJ1
Hoffmann, U1
Kane, GC1
Doyle, BJ1
Lerman, A1
Barsness, GW1
Best, PJ1
Rihal, CS1
Berman, EL1
Urban, BA1
Curry, CA1
Lane, JL1
Jennings, RS1
McCulloch, CC1
Hsieh, J1
Londt, JH1
Schepis, T1
Scheffel, H1
Jo, SH1
Koo, BK1
Park, JS1
Kang, HJ1
Cho, YS1
Kim, YJ1
Youn, TJ1
Chung, WY1
Chae, IH1
Choi, DJ1
Sohn, DW1
Oh, BH1
Park, YB1
Choi, YS1
Kim, HS1
Tveit, K1
Bolz, KD1
Bolstad, B1
Haugland, T1
Berg, KJ2
Skjaerpe, T1
Kloster, YF1
Kløw, NE2
Levorstad, K1
Brodahl, U1
Endresen, K1
Kristoffersen, DT1
Laake, B1
Simonsen, S1
Tofte, AJ1
Lundby, B1
Fransson, SG1
Stenport, G1
Andersson, M1
Grabowski, EF1
Boor, SE1
Rodino, LJ1
Jang, IK1
Gold, H1
Michelson, AD1
Baumgart, D1
Haude, M1
George, G1
Ge, J1
Rosenbaum, S1
Caspari, G1
Liu, F1
Erbel, R1
Brinker, JA2
Limbruno, U1
Petronio, AS1
Amoroso, G1
Baglini, R1
Paterni, G1
Merelli, A1
Mariotti, R1
Mariani, M1
Davidson, CJ1
Laskey, WK1
Hermiller, JB1
Harrison, JK1
Matthai, W1
Vlietstra, RE1
Kereiakes, DJ1
Muhlestein, JB1
Lansky, A1
Popma, JJ1
Buchbinder, M1
Hirshfeld, JW1
Rienmüller, R1
Brekke, O1
Kampenes, VB1
Reiter, U1
Mortensen, E1
Refsum, H1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
BIcarbonato di Sodio e N-Acetilcisteina Nella Prevenzione Della Nefropatia da Mezzo di Contrasto Nell'infaRto mIocardico acutO(Registro BINARIO)[NCT01218178]520 participants (Actual)Observational2008-06-30Completed
Heart Rate Controller in Computed Tomography Coronary Angiography: A Randomized Controlled Trial of Metoprolol, Diltiazem and Ivabradine[NCT05261464]Phase 4246 participants (Anticipated)Interventional2021-01-30Recruiting
Prevention of Radiocontrast Media Induced Nephropathy by Short-Term High-Dose Statin in Renal Insufficiency Undergoing Coronary Angiography (PROMISS)[NCT00259441]Phase 4320 participants Interventional2005-02-28Completed
Multivariable Assessment of Coronary Artery Disease Using Cardiac CT Imaging[NCT00857792]120 participants (Actual)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ability to Detect Stress-induced Myocardial Perfusion Abnormalities by Analysis of MDCT Images Confirmed by Coronary Angiography and/or SPECT.

(NCT00857792)
Timeframe: 3 months

Intervention% accurately detected perfusion defects (Number)
Open Label78

Trials

12 trials available for iodixanol and Coronary Disease

ArticleYear
Nephrotoxicity of iodixanol versus ioversol in patients with chronic kidney disease: the Visipaque Angiography/Interventions with Laboratory Outcomes in Renal Insufficiency (VALOR) Trial.
    American heart journal, 2008, Volume: 156, Issue:4

    Topics: Aged; Aged, 80 and over; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Diabeti

2008
Renal Insufficiency Following Radiocontrast Exposure Trial (REINFORCE): a randomized comparison of sodium bicarbonate versus sodium chloride hydration for the prevention of contrast-induced nephropathy.
    Coronary artery disease, 2008, Volume: 19, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind

2008
Is treatment with N-acetylcysteine to prevent contrast-induced nephropathy when using bicarbonate hydration out of date?
    Clinical nephrology, 2008, Volume: 70, Issue:6

    Topics: Acetylcysteine; Aged; Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind Method; D

2008
Intravenous contrast material administration at 16-detector row helical CT coronary angiography: test bolus versus bolus-tracking technique.
    Radiology, 2004, Volume: 233, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aorta, Thoracic; Aortography; Contrast Media; Coronary Angiography;

2004
Evaluation of a semiautomatic software tool for left ventricular function analysis with 16-slice computed tomography.
    European radiology, 2006, Volume: 16, Issue:1

    Topics: Contrast Media; Coronary Disease; Female; Heart Ventricles; Humans; Image Processing, Computer-Assis

2006
Effects of non-ionic iodinated contrast media on patient heart rate and pressures during intra-cardiac or intra-arterial injection.
    International journal of cardiology, 2007, Jun-12, Volume: 118, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Angiocardiography; Angiography, Digital Subtra

2007
Prevention of radiocontrast medium-induced nephropathy using short-term high-dose simvastatin in patients with renal insufficiency undergoing coronary angiography (PROMISS) trial--a randomized controlled study.
    American heart journal, 2008, Volume: 155, Issue:3

    Topics: Administration, Oral; Aged; Contrast Media; Coronary Angiography; Coronary Disease; Dose-Response Re

2008
Iodixanol in cardioangiography. A double-blind parallel comparison between iodixanol 320 mg I/ml and ioxaglate 320 mg I/ml.
    Acta radiologica (Stockholm, Sweden : 1987), 1994, Volume: 35, Issue:6

    Topics: Adult; Aged; Angiocardiography; Contrast Media; Coronary Disease; Double-Blind Method; Female; Human

1994
Iodixanol in cardioangiography in patients with coronary artery disease. Tolerability, cardiac and renal effects.
    Acta radiologica (Stockholm, Sweden : 1987), 1993, Volume: 34, Issue:1

    Topics: Adult; Aged; Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind Method; Hemodynami

1993
Immediate and late adverse reactions in coronary angiography. A comparison between iodixanol and ioxaglate.
    Acta radiologica (Stockholm, Sweden : 1987), 1996, Volume: 37, Issue:2

    Topics: Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind Method; Female; Hemodynamics; H

1996
Randomized trial of contrast media utilization in high-risk PTCA: the COURT trial.
    Circulation, 2000, May-09, Volume: 101, Issue:18

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Disease; Double-Blind Method; Female;

2000
Dimeric versus monomeric nonionic contrast agents in visualization of coronary arteries.
    European journal of radiology, 2001, Volume: 38, Issue:3

    Topics: Contrast Media; Coronary Angiography; Coronary Disease; Double-Blind Method; Electrocardiography; Fe

2001

Other Studies

24 other studies available for iodixanol and Coronary Disease

ArticleYear
320-row coronary computed tomography angiography (CCTA) with automatic exposure control (AEC): effect of 100 kV versus 120 kV on image quality and dose exposure.
    La Radiologia medica, 2016, Volume: 121, Issue:8

    Topics: Cardiac-Gated Imaging Techniques; Computed Tomography Angiography; Contrast Media; Coronary Disease;

2016
Evaluation of a body mass index-adapted protocol for low-dose 64-MDCT coronary angiography with prospective ECG triggering.
    AJR. American journal of roentgenology, 2009, Volume: 192, Issue:3

    Topics: Adult; Aged; Body Mass Index; Clinical Protocols; Contrast Media; Coronary Angiography; Coronary Dis

2009
Low-dose coronary CT angiography with prospective ECG triggering: validation of a contrast material protocol adapted to body mass index.
    AJR. American journal of roentgenology, 2009, Volume: 193, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Body Mass Index; Contrast Media; Coronary Angiography; Coronary Dise

2009
Comparison of iodixanol and ioversol for the prevention of contrast-induced nephropathy in diabetic patients after coronary angiography or angioplasty.
    Revista espanola de cardiologia, 2009, Volume: 62, Issue:12

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Disease; Creati

2009
Estimated radiation dose reduction using adaptive statistical iterative reconstruction in coronary CT angiography: the ERASIR study.
    AJR. American journal of roentgenology, 2010, Volume: 195, Issue:3

    Topics: Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary Disease; Female; Humans; Lin

2010
Adaptive statistical iterative reconstruction: assessment of image noise and image quality in coronary CT angiography.
    AJR. American journal of roentgenology, 2010, Volume: 195, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Contrast Media; Coronary Angiography; Coronary

2010
Reproducibility of coronary optical coherence tomography for lumen and length measurements in humans (The CLI-VAR [Centro per la Lotta contro l'Infarto-VARiability] study).
    The American journal of cardiology, 2012, Oct-15, Volume: 110, Issue:8

    Topics: Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Disease; Coronary Ves

2012
Test-bolus versus bolus-tracking techniques for CT angiographic timing.
    Radiology, 2005, Volume: 236, Issue:1

    Topics: Aorta, Thoracic; Aortography; Contrast Media; Coronary Angiography; Coronary Disease; Electrocardiog

2005
Diagnostic accuracy of multislice computed tomography coronary angiography is improved at low heart rates.
    The international journal of cardiovascular imaging, 2006, Volume: 22, Issue:1

    Topics: Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary Disease; Female; Heart Rate;

2006
Dynamic cine imaging of the mitral valve with 16-MDCT: a feasibility study.
    AJR. American journal of roentgenology, 2005, Volume: 185, Issue:3

    Topics: Aged; Artifacts; Contrast Media; Coronary Disease; Echocardiography; Electrocardiography; Feasibilit

2005
Noninvasive visualization of the coronary arteries with multi-slice computed tomography; influence of heart rate on diagnostic accuracy.
    The international journal of cardiovascular imaging, 2006, Volume: 22, Issue:1

    Topics: Contrast Media; Coronary Angiography; Coronary Disease; Heart Rate; Humans; Statistics, Nonparametri

2006
Contrast-induced nephropathy in urgent coronary interventions.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2006, Volume: 7, Issue:10

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary;

2006
In-vivo flow simulation in coronary arteries based on computed tomography datasets: feasibility and initial results.
    European radiology, 2007, Volume: 17, Issue:5

    Topics: Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary Dise

2007
Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Incidence; Ioxa

2007
Evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in coronary angiography.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Ioxaglic Acid;

2007
Efficacy of pre-scan beta-blockade and impact of heart rate on image quality in patients undergoing coronary multidetector computed tomography angiography.
    European journal of radiology, 2008, Volume: 66, Issue:1

    Topics: Adrenergic beta-Antagonists; Artifacts; Chi-Square Distribution; Contrast Media; Coronary Angiograph

2008
Ultra-low contrast volumes reduce rates of contrast-induced nephropathy in patients with chronic kidney disease undergoing coronary angiography.
    Journal of the American College of Cardiology, 2008, Jan-01, Volume: 51, Issue:1

    Topics: Aged; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Dose-Response Relationship

2008
Prospectively gated transverse coronary CT angiography versus retrospectively gated helical technique: improved image quality and reduced radiation dose.
    Radiology, 2008, Volume: 246, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Contrast Media; Coronary Angiography; Coronary Di

2008
Coronary 64-slice CT angiography predicts outcome in patients with known or suspected coronary artery disease.
    European radiology, 2008, Volume: 18, Issue:6

    Topics: Chi-Square Distribution; Contrast Media; Coronary Angiography; Coronary Disease; Female; Humans; Mal

2008
Platelets are degranulated by some, but not all, contrast media.
    Academic radiology, 1996, Volume: 3 Suppl 2

    Topics: Aspirin; Cells, Cultured; Contrast Media; Coronary Angiography; Coronary Disease; Diatrizoate; Flow

1996
High-volume nonionic dimeric contrast medium: first experiences during complex coronary interventions.
    Catheterization and cardiovascular diagnosis, 1997, Volume: 40, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Coronary Disease; Creati

1997
"Limitless" contrast for coronary angiography?
    Catheterization and cardiovascular diagnosis, 1997, Volume: 40, Issue:3

    Topics: Contrast Media; Coronary Angiography; Coronary Disease; Dose-Response Relationship, Drug; Humans; Tr

1997
The impact of coronary artery disease on the coronary vasomotor response to nonionic contrast media.
    Circulation, 2000, Feb-08, Volume: 101, Issue:5

    Topics: Aged; Cardiovascular Agents; Contrast Media; Coronary Angiography; Coronary Circulation; Coronary Di

2000
Left ventricular systolic and diastolic function during coronary arteriography before and after acute left ventricular failure in dogs. A comparison between iodixanol, iohexol and ioxaglate.
    Acta radiologica (Stockholm, Sweden : 1987), 1991, Volume: 32, Issue:2

    Topics: Acute Disease; Animals; Blood Pressure; Cardiac Output; Cardiac Output, Low; Contrast Media; Coronar

1991