Page last updated: 2024-10-29

iodixanol and Aortic Aneurysm

iodixanol has been researched along with Aortic Aneurysm in 5 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.

Research Excerpts

ExcerptRelevanceReference
"Acute aortic dissection (AAD) is a life-threatening condition making early diagnosis critical."1.48Variation in emergency department use of computed tomography for investigation of acute aortic dissection. ( Anjum, O; Bleeker, H; Ohle, R; Perry, JJ; Wells, G, 2018)
"Aortoiliac aneurysm imaging can be performed with substantially reduced amounts of contrast medium using 64-detector computed tomography angiography technology."1.35Adequacy of an early arterial phase low-volume contrast protocol in 64-detector computed tomography angiography for aortoiliac aneurysms. ( Benenati, JF; Diehm, N; Katzen, BT; Pena, C; Tsoukas, AI, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Ghaghada, KB1
Ren, P1
Devkota, L1
Starosolski, Z1
Zhang, C1
Vela, D1
Stupin, IV1
Tanifum, EA1
Annapragada, AV1
Shen, YH1
LeMaire, SA1
Ohle, R1
Anjum, O1
Bleeker, H1
Wells, G1
Perry, JJ1
Shuman, WP1
O'Malley, RB1
Busey, JM1
Ramos, MM1
Koprowicz, KM1
Husmann, L1
Leschka, S1
Salzberg, SP1
Lachat, M1
Genoni, M1
Marincek, B1
Alkadhi, H1
Diehm, N1
Pena, C1
Benenati, JF1
Tsoukas, AI1
Katzen, BT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Does Reduction in Contrast Administration Dose in Computed Tomography Arteriograms Degrade Image Quality? A Single Institutional Review of an Ultra-low Contrast Dose Protocol[NCT02669784]34 participants (Actual)Interventional2016-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ascending Sinotubular Junction Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. Measurement was taken at the ascending aorta near the sinotubular junction. (NCT02669784)
Timeframe: At 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)246.4
Contrast (Omnipaque) Low Dose (50mL)287.5

Burfication Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the distal abdominal aorta prior to the bifurcation. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)336.2
Contrast (Omnipaque) Low Dose (50mL)321.2

Celiac Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the proximal abdominal aorta at the level of the celiac axis. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)243.8
Contrast (Omnipaque) Low Dose (50mL)329.5

CTA Vessel Opacification Grading 1

"5 Point Grading Scale was used to determine CTA Vessel Opacification by a Board Certified Radiologist.~Poor opacification with no difference in attenuation of the lumen compared to the wall of the vessel. Non diagnostic.~Decreased opacification. Little to no difference in attenuation between the lumen and the wall. Non diagnostic.~Moderate opacification of the lumen of the vessel. Diagnostic study.~Good opacification of the lumen of the vessel.~Excellent opacification of the lumen of the vessel with distinct difference in attenuation of the wall and lumen of the vessel." (NCT02669784)
Timeframe: 30 days

Interventionscore on a scale (Mean)
Contrast (Omnipaque) Low Dose (40mL)4
Contrast (Omnipaque) Low Dose (50mL)4.3

CTA Vessel Opacification Grading 2

"5 Point Grading Scale was used to determine CTA Vessel Opacification by a second Board Certified Radiologist.~Poor opacification with no difference in attenuation of the lumen compared to the wall of the vessel. Non diagnostic.~Decreased opacification. Little to no difference in attenuation between the lumen and the wall. Non diagnostic.~Moderate opacification of the lumen of the vessel. Diagnostic~Good opacification of the lumen of the vessel.~Excellent opacification of the lumen of the vessel with distinct difference in attenuation of the wall and lumen of the vessel." (NCT02669784)
Timeframe: 30 days

Interventionscore on a scale (Mean)
Contrast (Omnipaque) Low Dose (40mL)4.2
Contrast (Omnipaque) Low Dose (50mL)4.4

Descending Thoracic Aorta Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the distal abdominal aorta prior to the bifurcation. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (40mL)261.9
Contrast (Omnipaque) Low Dose (50mL)312.8

Left Common Femoral Artery Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the right common femoral artery. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (50mL)309.5

Right Common Femoral Artery Measurement

Following image acquisition, quantitative analysis was performed by measurement of the attenuation of the contrast bolus by use of Hounsfield Units. A measurement was taken from the right common femoral artery. (NCT02669784)
Timeframe: 30 days

InterventionHounsfield units (Mean)
Contrast (Omnipaque) Low Dose (50mL)314.5

Other Studies

5 other studies available for iodixanol and Aortic Aneurysm

ArticleYear
Early Detection of Aortic Degeneration in a Mouse Model of Sporadic Aortic Aneurysm and Dissection Using Nanoparticle Contrast-Enhanced Computed Tomography.
    Arteriosclerosis, thrombosis, and vascular biology, 2021, Volume: 41, Issue:4

    Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Aortic Dissection; Aortic Rupture; Aortography; Com

2021
Variation in emergency department use of computed tomography for investigation of acute aortic dissection.
    Emergency radiology, 2018, Volume: 25, Issue:3

    Topics: Acute Disease; Adult; Aged; Aortic Aneurysm; Aortic Dissection; Contrast Media; Diagnosis, Different

2018
Prospective comparison of dual-energy CT aortography using 70% reduced iodine dose versus single-energy CT aortography using standard iodine dose in the same patient.
    Abdominal radiology (New York), 2017, Volume: 42, Issue:3

    Topics: Aged; Aortic Aneurysm; Computed Tomography Angiography; Contrast Media; Female; Humans; Iohexol; Mal

2017
Sixty-four-slice computed tomographic coronary angiography in pseudoaneurysm of the ascending aorta: a useful modality to supplement the diagnosis.
    The Journal of thoracic and cardiovascular surgery, 2006, Volume: 132, Issue:2

    Topics: Anastomosis, Surgical; Aneurysm, False; Aortic Aneurysm; Cardiac Catheterization; Contrast Media; Co

2006
Adequacy of an early arterial phase low-volume contrast protocol in 64-detector computed tomography angiography for aortoiliac aneurysms.
    Journal of vascular surgery, 2008, Volume: 47, Issue:3

    Topics: Aged; Aortic Aneurysm; Aortography; Contrast Media; Female; Humans; Iliac Aneurysm; Injections, Intr

2008