Page last updated: 2024-10-29

iodixanol and Acute Kidney Failure

iodixanol has been researched along with Acute Kidney Failure in 92 studies

iodixanol: dimeric contrast media; structure given in first source
iodixanol : A dimeric, non-ionic, water-soluble, radiographic contrast agent, used particularly in coronary angiography.

Research Excerpts

ExcerptRelevanceReference
"To evaluate iodixanol-associated acute kidney injury (AKI) and prognosis in patients undergoing elective percutaneous coronary intervention (PCI)."8.31Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study. ( Azzalini, L; Chen, Z; Huang, L; Jiang, Y; Mao, Q; Xiang, L; Zhao, N; Zhao, X; Zhou, D, 2023)
"To determine the incidence of post-contrast acute kidney injury (PC-AKI) and presumed contrast-induced acute kidney injury (CI-AKI) following contrast-enhanced CT (CECT) with intravenous application of a reduced dose of the iso-osmolar contrast agent iodixanol in cancer patients with chronic kidney disease."7.96Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol. ( Bez, C; Hinterleitner, C; Horger, M; Werner, S, 2020)
"In this study, we tested the hypothesis that fasudil, a Rho kinase inhibitor, would protect against contrast-induced acute kidney injury (CI-AKI) in a mouse model and attempted to elucidate the mechanism involved."7.88Rho Kinase Inhibitor, Fasudil, Attenuates Contrast-induced Acute Kidney Injury. ( Miao, D; Wang, Y; Yang, Z; Zhang, D; Zhang, H, 2018)
"The combined prophylactic strategy of sodium bicarbonate plus N-acetylsyteine (NAC) seems to be effective in preventing contrast induced acute kidney injury (CI-AKI) in patients at low-to-medium risk."6.25Renal insufficiency following contrast media administration trial II (REMEDIAL II): RenalGuard system in high-risk patients for contrast-induced acute kidney injury: rationale and design. ( Briguori, C; Condorelli, G; Ricciardelli, B; Visconti, G, 2011)
"Iso-osmolar Iodixanol is associated with a lower rate of contrast-induced acute kidney injury (CI-AKI) in patients at increased risk compared to low-osmolar contrast media (LOCM)."4.93Economic impact of contrast-induced acute kidney injury associated with invasive cardiology: role of iso-osmolar contrast media in Germany, Italy, Poland, and Spain. ( De Francesco, M; Hernández, F; Lamotte, M; Ronco, C; Wacinski, PJ; Wessely, R, 2016)
"To evaluate iodixanol-associated acute kidney injury (AKI) and prognosis in patients undergoing elective percutaneous coronary intervention (PCI)."4.31Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study. ( Azzalini, L; Chen, Z; Huang, L; Jiang, Y; Mao, Q; Xiang, L; Zhao, N; Zhao, X; Zhou, D, 2023)
"Iodixanol is associated with lower rates of contrast-induced acute kidney injury (CI-AKI)."4.02Effects of a High Dose of the Contrast Medium Iodixanol on Renal Function in Patients Following Percutaneous Coronary Intervention. ( Azzalini, L; Chen, Z; Huang, L; Jin, J; Li, L; Mao, Q; Song, Y; Tong, W; Xu, Q; Xu, Z; Zhao, N; Zhao, X; Zhou, Y, 2021)
"The aim of this study was to investigate clinical (contrast-induced acute kidney injury [CI-AKI]) and subclinical CI-AKI (SCI-AKI) after intra-arterial administration of Iodixanol and Iopamidol in patients with an estimated glomerular filtration rate (eGFR) ≥60 mL/min/1."3.96Subclinical Contrast-Induced Acute Kidney Injury in Patients Undergoing Cerebral Computed Tomography. ( Ankawi, G; Biolo, G; Breglia, A; Brocca, A; Carta, M; De Cal, M; Giavarina, D; Godi, I; Guglielmetti, G; Iannucci, G; Passannante, A; Ronco, C; Virzì, GM; Yun, X, 2020)
"To determine the incidence of post-contrast acute kidney injury (PC-AKI) and presumed contrast-induced acute kidney injury (CI-AKI) following contrast-enhanced CT (CECT) with intravenous application of a reduced dose of the iso-osmolar contrast agent iodixanol in cancer patients with chronic kidney disease."3.96Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol. ( Bez, C; Hinterleitner, C; Horger, M; Werner, S, 2020)
" Rats were treated with Iodixanol to prepare a contrast-induced acute kidney injury (CIAKI) model."3.96Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway. ( Pang, T; Ren, K; Wang, Y; Zhang, H; Zuo, Z, 2020)
"In this study, we tested the hypothesis that fasudil, a Rho kinase inhibitor, would protect against contrast-induced acute kidney injury (CI-AKI) in a mouse model and attempted to elucidate the mechanism involved."3.88Rho Kinase Inhibitor, Fasudil, Attenuates Contrast-induced Acute Kidney Injury. ( Miao, D; Wang, Y; Yang, Z; Zhang, D; Zhang, H, 2018)
"Rats received nitric oxide synthase inhibitor L-NAME (10 mg/kg) and cyclooxygenase inhibitor indomethacin (10 mg/kg) to induce the risk for developing iodinated contrast-induced acute kidney injury before receiving one of the interventions: NAC, furosemide, or placebo."3.80Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker. ( Franklin, T; Li, LP; Lu, J; Papadopoulou, MV; Prasad, PV; Solomon, R; Thacker, J; Zhou, Y, 2014)
"To compare the incidence of contrast medium-induced acute kidney injury (AKI) after intravenous (IV) administration of iodixanol for computed tomographic (CT) angiography versus intraarterial (IA) injection of iodixanol or low osmolar contrast medium (LOCM) for digital subtraction angiography (DSA) within the same population suspected of peripheral arterial occlusive disease (PAOD)."3.77Contrast medium-induced acute kidney injury: comparison of intravenous and intraarterial administration of iodinated contrast medium. ( Dohad, SY; Karlsberg, RP; Sheng, R, 2011)
" The secondary endpoints were the mean peak SCr increase within 72 h after receiving CM and major adverse renal events (SCr increased by two times after 30 days, the need for dialysis treatment, rehospitalization for acute renal failure, or kidney-related death) during hospitalization and within 30 day postdischarge."2.87Nephrotoxicity of iodixanol versus iopamidol in patients undergoing peripheral angiography with or without endovascular therapy. ( Che, WQ; Chen, Y; Dong, H; Gao, RL; Jiang, XJ; Peng, M; Xiong, HL; Xu, B; Yang, YJ; Zou, YB, 2018)
" The secondary endpoints are absolute and relative increases in sCr of at least 50%, thrombolysis in myocardial infarction (TIMI) perfusion grade, and major adverse cardiac events at 1, 6, and 12 months."2.75The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study. ( Angioli, P; Bolognese, L; Carrera, A; Ducci, K; Falsini, G; Grotti, S; Liistro, F; Limbruno, U; Picchi, A; Pierli, C, 2010)
"The relationship of contrast-induced nephropathy (CIN) to long-term adverse events (AEs) is controversial."2.74Contrast-induced nephropathy and long-term adverse events: cause and effect? ( Barrett, BJ; Doucet, S; Gelormini, JL; Katholi, RE; Labinaz, M; Mehran, R; Natarajan, MK; Sharma, SK; Solomon, RJ; Staniloae, CS, 2009)
"Iodixanol was cost-effective compared with iohexol, with both lower costs and better effects related to fewer adverse drug reactions."2.71Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy. ( Aspelin, P; Aubry, P; Fransson, SG; Lundkvist, J; Strasser, R; Willenbrock, R, 2005)
"Contrast media can cause acute renal failure by direct toxic effects on the tubular cells and kidney ischemia."2.48Cost-effectiveness of iso- versus low-osmolality contrast media in outpatients with high risk of contrast medium-induced nephropathy. ( Chicaíza-Becerra, LA; Gamboa, Ó; García-Molina, M, 2012)
"Contrast-induced acute kidney injury is a prominent complication following cardiac catheterization, though the risk has progressively decreased in recent times with appropriate risk stratification and use of safer contrast agents."1.48Are iso-osmolar, as compared to low-osmolar, contrast media cost-effective in patients undergoing cardiac catheterization? An economic analysis. ( Akbari, A; Chow, BJW; Hiremath, S; Wells, GA, 2018)
"Inclusion criteria were STEMI patients taken for cardiac catheterization, excluding patients receiving hemodialysis due to end-stage renal disease (ESRD)."1.43The incidence and significance of acute kidney injury following emergent contrast administration in patients with STEMI and stroke. ( Allen, BR; Elie, MC; Marchick, MR; Shuster, JJ; Weeks, EC, 2016)
"Iodixanol treatment of tubules significantly increased the concentration of Apn A (n = 3-5) in the supernatant."1.42Diadenosine pentaphosphate modulates glomerular arteriolar tone and glomerular filtration rate. ( Carlström, M; Flöge, J; Heintz, B; Jankowski, J; Jankowski, V; Lai, EY; Liu, ZZ; Patzak, A; Sällström, J; Sendeski, MM, 2015)
"More necrosis was present after incubation with iohexol and iopamidol than after incubation with equal concentrations of iodixanol."1.40Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury. ( Cafiero, C; Gesualdo, L; Grandaliano, G; Montemurno, E; Netti, GS; Prattichizzo, C; Ranieri, E; Rascio, F; Simone, S; Stallone, G, 2014)
" CM increased superoxide concentration and reduced nitric oxide bioavailability in TAL."1.40Iodinated contrast media cause direct tubular cell damage, leading to oxidative stress, low nitric oxide, and impairment of tubuloglomerular feedback. ( Cantow, K; Liu, R; Liu, ZZ; Lu, Y; Nikitina, T; Patzak, A; Perlewitz, A; Persson, PB; Schmerbach, K; Seeliger, E; Sendeski, MM, 2014)
"upon iodixanol injection was reduced almost to the level of iopromide when injecting iodixanol/mannitol (iopromide: 289 ± 68 HU vs iodixanol/mannitol: 343 ± 68 HU)."1.38The osmolality of nonionic, iodinated contrast agents as an important factor for renal safety. ( Ellinghaus, P; Ernst, R; Jost, G; Lengsfeld, P; Lenhard, DC; Pietsch, H; Sieber, MA, 2012)
"The odds ratio of acute kidney failure on day 5 was 0."1.38Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease. ( Ghahramani, N; Lapsiwala, A; Parhizgar, A; Saadulla, L; Spatz, C, 2012)
"Postoperative acute renal failure (ARF) is not uncommon after cardiac surgery and after angiography."1.35Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery. ( Ballotta, A; Bossone, E; Conti, D; De Benedetti, D; Kandil, H; Kunkl, A; Mehta, RH; Mollichelli, N; Ranucci, M, 2008)

Research

Studies (92)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.09)18.2507
2000's19 (20.65)29.6817
2010's61 (66.30)24.3611
2020's11 (11.96)2.80

Authors

AuthorsStudies
Ran, F1
Yang, Y1
Yang, L1
Chen, S1
He, P1
Liu, Q1
Zou, Q1
Wang, D1
Hou, J1
Wang, P1
Cheng, L1
Wang, L1
Chen, B1
Wang, C1
Wang, M1
Li, J1
Gao, X1
Zhang, Z1
Han, L1
Chen, Z3
Mao, Q2
Xiang, L1
Zhou, D1
Jiang, Y1
Zhao, N3
Huang, L2
Azzalini, L3
Zhao, X3
Zhang, Y1
Zhao, R1
Hami, M1
Bigdeli, A1
Khameneh Bagheri, R1
Rajabi, O1
Salehi, M1
Zahedi Avval, F1
Li, Y1
Huang, J1
He, S1
Lu, Z1
Zhang, J1
Li, X1
Yang, Z2
Hoffman, RM1
Wu, Q1
Breglia, A1
Godi, I1
Virzì, GM1
Guglielmetti, G1
Iannucci, G1
De Cal, M1
Brocca, A1
Carta, M1
Giavarina, D1
Ankawi, G1
Passannante, A1
Yun, X1
Biolo, G1
Ronco, C3
Sharma, A1
Kilari, S1
Cai, C1
Simeon, ML1
Misra, S2
Werner, S1
Bez, C1
Hinterleitner, C1
Horger, M1
Wang, Y3
Zhang, H3
Pang, T1
Zuo, Z1
Ren, K3
Zhou, Y3
Xu, Q1
Xu, Z1
Tong, W1
Li, L1
Song, Y1
Jin, J1
Suh, K1
Kellum, JA1
Kane-Gill, SL1
Miao, D1
Zhang, D1
Takahashi, EA1
Kallmes, DF2
Fleming, CJ1
McDonald, RJ2
McKusick, MA1
Bjarnason, H1
Harmsen, WS1
Keuffel, E1
McCullough, PA4
Todoran, TM1
Brilakis, ES1
Palli, SR1
Ryan, MP1
Gunnarsson, C1
Tecson, KM1
Brown, D1
Choi, JW1
Feghali, G1
Gonzalez-Stawinski, GV1
Hamman, BL1
Hebeler, R1
Lander, SR1
Lima, B1
Potluri, S1
Schussler, JM1
Stoler, RC1
Velasco, C1
Lei, R1
Zhao, F2
Tang, CY2
Luo, M2
Yang, SK1
Cheng, W2
Li, XW2
Duan, SB2
Hiremath, S1
Akbari, A1
Wells, GA1
Chow, BJW1
Xiong, HL1
Peng, M1
Jiang, XJ1
Dong, H2
Che, WQ1
Chen, Y1
Zou, YB1
Xu, B1
Yang, YJ1
Gao, RL1
Vilca, LM1
Lombardo, F1
Poletti, E1
Laricchia, A1
Beneduce, A1
Maccagni, D1
Demir, OM1
Slavich, M1
Giannini, F1
Carlino, M2
Margonato, A1
Cappelletti, A1
Colombo, A2
Gerk, U1
Franke, RP2
Krüger-Genge, A2
Jung, F2
Kofman, N1
Margolis, G1
Gal-Oz, A1
Letourneau-Shesaf, S1
Keren, G1
Rozenbaum, Z1
Shacham, Y1
Castaldo, P1
Frascà, GM1
Brigante, F1
Ferrante, L1
Magi, S1
Pavani, M1
Skrami, E1
Giuseppetti, GM1
Polonara, G1
Amoroso, S1
Wang, Z1
Zhang, X1
Hua, Z1
Xie, L1
Jiang, X1
Wang, R1
Gao, P1
Lamby, P1
Mrowietz, C1
Falter, J1
Graf, S1
Schellenberg, EL1
Prantl, L1
Hill, M1
Mor, MK1
Travis, L1
Ward, T1
Palevsky, PM1
Ramkumar, M1
Weisbord, SD2
Limbruno, U3
Picchi, A3
Micheli, A1
Calabria, P1
Cortese, B1
Brizi, G1
Severi, S1
De Caterina, R1
Seeliger, E2
Cantow, K2
Arakelyan, K1
Ladwig, M1
Persson, PB2
Flemming, B1
Netti, GS1
Prattichizzo, C1
Montemurno, E1
Simone, S1
Cafiero, C1
Rascio, F1
Stallone, G1
Ranieri, E1
Grandaliano, G1
Gesualdo, L1
Liu, ZZ2
Schmerbach, K1
Lu, Y1
Perlewitz, A1
Nikitina, T1
Patzak, A2
Liu, R1
Sendeski, MM2
Maioli, M2
Toso, A2
Leoncini, M2
Musilli, N1
Bellandi, F2
Rosner, MH1
Li, LP2
Lu, J2
Papadopoulou, MV2
Franklin, T2
Bokhary, U1
Solomon, R3
Sen, A1
Prasad, PV2
Thacker, J1
Wang, YC1
Tang, A1
Chang, D1
Zhang, SJ1
Ju, S1
Chua, HR1
Horrigan, M1
Mcintosh, E1
Bellomo, R1
Schmalfuss, CM1
Woodard, PK1
Gitter, MJ1
Jadhav, MP1
Bellinger, RL1
Rose, SC1
Bavry, AA1
Choi, MJ1
Yoon, JW1
Han, SJ1
Choi, HH1
Song, YR1
Kim, SG1
Oh, JE1
Lee, YK1
Seo, JW1
Kim, HJ1
Noh, JW1
Koo, JR1
McDonald, JS1
Carter, RE1
Hartman, RP1
Katzberg, RW1
Williamson, EE1
Mariani, J1
Guedes, C1
Soares, P1
Zalc, S1
Campos, CM1
Lopes, AC1
Spadaro, AG1
Perin, MA1
Filho, AE1
Takimura, CK1
Ribeiro, E1
Kalil-Filho, R1
Edelman, ER1
Serruys, PW1
Lemos, PA1
Carlström, M1
Lai, EY1
Sällström, J1
Flöge, J1
Heintz, B1
Jankowski, J1
Jankowski, V1
Liu, TQ1
Luo, WL1
Tan, X1
Fang, Y1
Chen, J1
Yu, XF1
Cai, JR1
Ding, XQ1
Danziger, J1
Thummalakunta, L1
Nelson, R1
Faintuch, S1
Yao, L1
Zhao, CX1
Gu, X1
Tan, TW1
Hamidian Jahromi, A1
Zhang, WW1
Kobalava, ZD1
Villevalde, SV1
Gaskina, AA1
Mayskov, VV1
Moiseev, VS1
Quintavalle, C1
Anselmi, CV1
De Micco, F1
Roscigno, G1
Visconti, G2
Golia, B1
Focaccio, A2
Ricciardelli, B3
Perna, E1
Papa, L1
Donnarumma, E1
Condorelli, G3
Briguori, C3
Shema-Didi, L1
Kristal, B1
Eizenberg, S1
Marzuq, N1
Sussan, M1
Feldman-Idov, Y1
Ofir, P1
Atar, S1
Barbanti, M1
Gulino, S1
Capranzano, P1
Immè, S1
Sgroi, C1
Tamburino, C2
Ohno, Y1
Attizzani, GF1
Patanè, M1
Sicuso, R1
Pilato, G1
Di Landro, A1
Todaro, D1
Di Simone, E1
Picci, A1
Giannetto, G1
Costa, G1
Deste, W1
Giannazzo, D1
Grasso, C1
Capodanno, D1
De Francesco, M1
Wacinski, PJ1
Wessely, R1
Hernández, F1
Lamotte, M1
Giustino, G1
Baber, U1
Mastoris, I1
Vlachojannis, GJ1
Yu, J1
Teirstein, PS1
Downey, WE1
Batchelor, WB1
Casterella, PJ1
Nikolsky, E1
Wong, SC1
Theodoropoulos, KN1
Dangas, GD1
Mehran, R2
Marchick, MR1
Allen, BR1
Weeks, EC1
Shuster, JJ1
Elie, MC1
Valero, E1
Rodríguez, JC1
Moyano, P1
Miñana, G1
Sanchis, J1
Núñez, J1
Rezaei, Y1
Khademvatani, K1
Rahimi, B1
Khoshfetrat, M1
Arjmand, N1
Seyyed-Mohammadzad, MH1
Wu, CJ1
Bao, ML1
Wang, Q1
Wang, XN1
Liu, XS1
Shi, HB1
Zhang, YD1
Fananapazir, G1
Troppmann, C1
Corwin, MT1
Nikpour, AM1
Naderi, S1
Lamba, R1
Barbieri, L1
Verdoia, M1
Nardin, M1
Marino, P1
Suryapranata, H1
De Luca, G1
Sanon, S1
Barsness, GW1
Gulati, R1
Nie, B1
Cheng, WJ1
Li, YF1
Cao, Z1
Yang, Q1
Zhao, YX1
Guo, YH1
Zhou, YJ1
Heinrich, MC1
Häberle, L1
Müller, V1
Bautz, W1
Uder, M1
Chuang, FR1
Chen, TC1
Wang, IK1
Chuang, CH1
Chang, HW1
Ting-Yu Chiou, T1
Cheng, YF1
Lee, WC1
Chen, WC1
Yang, KD1
Lee, CH1
Agrawal, V1
Swami, A1
Kosuri, R1
Alsabbagh, M1
Agarwal, M1
Samarapungavan, D1
Rocher, LL1
Solomon, RJ1
Natarajan, MK1
Doucet, S1
Katholi, RE1
Staniloae, CS1
Sharma, SK1
Labinaz, M1
Gelormini, JL1
Barrett, BJ1
Capasso, P1
Vasheghani-Farahani, A1
Sadigh, G1
Kassaian, SE1
Khatami, SM1
Fotouhi, A1
Razavi, SA1
Mansournia, MA1
Yamini-Sharif, A1
Amirzadegan, A1
Salarifar, M1
Sadeghian, S1
Davoodi, G1
Borumand, MA1
Esfehani, FA1
Darabian, S1
Bolognese, L2
Falsini, G2
Grotti, S2
Liistro, F2
Carrera, A2
Angioli, P2
Ducci, K2
Pierli, C2
Gallopin, M1
Tedeschi, D1
Micheletti, C1
Cho, JY1
Jeong, MH1
Hwan Park, S1
Kim, IS1
Park, KH1
Sim, DS1
Yoon, NS1
Yoon, HJ1
Park, HW1
Hong, YJ1
Kim, JH1
Ahn, Y1
Cho, JG1
Park, JC1
Kang, JC1
Matejka, J1
Varvarovsky, I1
Vojtisek, P1
Herman, A1
Rozsival, V1
Borkova, V1
Kvasnicka, J1
Reed, MC1
Moscucci, M1
Smith, DE1
Share, D1
LaLonde, T1
Mahmood, SA1
D'Haem, C1
McNamara, R1
Greenbaum, A1
Gurm, HS1
Serafin, Z1
Karolkiewicz, M1
Gruszka, M1
Strózecki, P1
Lasek, W1
Odrowaz-Sypniewska, G1
Manitius, J1
Beuth, W1
Karlsberg, RP1
Dohad, SY1
Sheng, R1
Wi, J1
Ko, YG1
Kim, JS1
Kim, BK1
Choi, D1
Ha, JW1
Hong, MK1
Jang, Y1
Schwenke, C1
Lenhard, DC1
Pietsch, H1
Sieber, MA1
Ernst, R1
Lengsfeld, P1
Ellinghaus, P1
Jost, G1
Spatz, C1
Saadulla, L1
Lapsiwala, A1
Parhizgar, A1
Ghahramani, N1
Chicaíza-Becerra, LA1
García-Molina, M1
Gamboa, Ó1
Ludwig, U1
Connemann, J1
Keller, F1
Boccalandro, F1
Amhad, M1
Smalling, RW1
Sdringola, S1
Dean, LS1
Aspelin, P1
Aubry, P1
Fransson, SG1
Strasser, R1
Willenbrock, R1
Lundkvist, J1
Cowburn, PJ1
Patel, H1
Pipes, RR1
Parker, JD1
Sherwin, PF1
Cambron, R1
Johnson, JA1
Pierro, JA1
Airoldi, F1
Morici, N1
Sangiorgi, GM1
Violante, A1
Montorfano, M1
Valente, S1
Lazzeri, C1
Giglioli, C1
Margheri, M1
Comeglio, M1
Nicolaci, L1
Chechi, T1
Gensini, GF1
Deray, G1
Persson, P1
Liss, P1
Hansell, P1
Möckel, M1
Radovic, M1
Kühnle, Y1
Combé, V1
Waigand, J1
Schröder, S1
Dietz, R1
Frei, U1
Eckardt, KU1
Ranucci, M1
Ballotta, A1
Kunkl, A1
De Benedetti, D1
Kandil, H1
Conti, D1
Mollichelli, N1
Bossone, E1
Mehta, RH1
Jakobsen, JA1

Clinical Trials (20)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Timing of Coronary Angiography and Multivariate Risk for Cardiac Surgery Associated Acute Kidney Injury and Major Adverse Renal and Cardiac Events (MARCE)[NCT02332070]965 participants (Actual)Observational2015-01-31Completed
Contrast-inDuced nephRotoxicity as Assessed by the Cystatin-modified KIdney Load-to-DAmage RElationship[NCT01908309]Early Phase 1150 participants (Actual)Interventional2013-04-30Completed
Personalized Versus Standard Hydration for Prevention of Contrast Induced Acute Kidney Injury. A Randomized Trial With Bioimpedance Analysis.[NCT02225431]Phase 4296 participants (Actual)Interventional2012-09-30Completed
Prevention of Contrast-Induced Acute Kidney Injury: Standard Versus Short Hydration Protocol in Patients With Normal Fluid Status Assessed by the Bioimpedance Analysis (The HYDRA II Study)[NCT04215042]1,000 participants (Anticipated)Interventional2016-05-01Recruiting
Functional MRI-based Assessment of Terlipressin vs. Octreotide on Renal Function in Cirrhotic Patients With Acute Variceal Bleeding (CHESS1903): A Multicenter, Single-blind, Randomised Controlled Trial[NCT04028323]Phase 460 participants (Anticipated)Interventional2019-07-16Recruiting
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease (ENRICH): A Randomized Controlled Trial[NCT05283512]254 participants (Anticipated)Interventional2022-04-20Recruiting
Renal Insufficiency Following Contrast Media Administration Trial IV: Contrast Media Volume Control for Limiting Contrast-Induced Acute Kidney in Acute Coronary Syndrome.[NCT04714736]522 participants (Anticipated)Interventional2020-02-10Recruiting
Minimizing cOntrast utiliZAtion With IVUS Guidance in coRonary angioplasTy: The MOZART Study[NCT01947335]Phase 483 participants (Actual)Interventional2012-11-30Completed
IVUS Based Ultra-low Volume Contrast Media PCI to Reduce Contrast Induced Nephrology in Patient With Chronic Kidney disease-a Multi-center, Open Label, Randomized Trial (IVUS-CKD)[NCT05913362]320 participants (Anticipated)Interventional2023-10-01Not yet recruiting
Renal Insufficiency Following Contrast Media Administration Trial II (Remedial II): The RenalGuard System in High-Risk Patients for Contrast-Induced Acute Kidney Injury[NCT01098032]Phase 3294 participants (Actual)Interventional2009-01-31Completed
[NCT02070679]Phase 3284 participants (Actual)Interventional2014-02-28Completed
Antioxidants for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization[NCT03755700]Phase 31,000 participants (Anticipated)Interventional2018-11-01Recruiting
CARE (Visipaque 320 and Isovue 370 in Cardiac Angiography in REnally Impaired Patients); FOLLOW-UP STUDY[NCT00479024]294 participants (Actual)Observational2007-06-30Completed
Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.[NCT05147831]300 participants (Anticipated)Interventional2021-11-30Recruiting
The Contrast Media and Nephrotoxicity Following Coronary Revascularization by Primary Angioplasty for Acute Myocardial Infarction. The CONTRAST-AMI Study.[NCT00827788]Phase 4432 participants (Anticipated)Interventional2008-12-31Completed
Department of Geriatrics[NCT02575092]Phase 2/Phase 34,000 participants (Actual)Interventional2015-11-01Completed
Predictive Value of CHA2DS2-VASC Score and Contrast Volume to Creatinine Clearance Ratio in Relation to Mehran Score for Contrast-Induced Nephropathy In ST- Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention[NCT03266458]210 participants (Anticipated)Observational [Patient Registry]2018-01-01Not yet recruiting
High Dose Atorvastatin Raises Threshold of Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention[NCT04375787]Phase 4200 participants (Actual)Interventional2020-03-15Completed
Evaluation of the Effect of Dapagliflozin on Cardiac Remodeling in Post Myocardial Infarction Patients[NCT05335629]60 participants (Anticipated)Interventional2022-09-01Recruiting
BIcarbonato di Sodio e N-Acetilcisteina Nella Prevenzione Della Nefropatia da Mezzo di Contrasto Nell'infaRto mIocardico acutO(Registro BINARIO)[NCT01218178]520 participants (Actual)Observational2008-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Incidence of Contrast-induced Nephropathy

Increase >= 0.5 mg/dl in basal serum creatinine (NCT01947335)
Timeframe: 7 days

Interventionpercentage of participants (Number)
Angiography-guided PCI19
IVUS-guided PCI7.3

Total Volume of Iodine Contrast Used During Procedure

Total volume of iodine contrast administered during the index procedure. (NCT01947335)
Timeframe: Day 1

Interventionml (Median)
Angiography-guided PCI64.5
IVUS-guided PCI20.0

Major Adverse Cardiac Events

Composite of death, myocardial infarction or repeat revascularization (NCT01947335)
Timeframe: 30 days and 6 months

,
Interventionparticipants (Number)
30 days6-months
Angiography-guided PCI22
IVUS-guided PCI25

Number of Participants With Contrast-induced Acute Kidney Injury

The primary outcome measure will be the rate of development of CI-AKI in the 2 study arms (number of participants). CI-AKI is defined as an increase in the serum creatinine concentration >=0.3 mg/dL from the baseline value at 48 hours after administration of the contrast media or the need for dialysis. (NCT01098032)
Timeframe: at 48 hours following contrast exposure

Interventionparticipants (Number)
Systemic Alone Therapy Group146
RenalGuard System Group146

Reviews

6 reviews available for iodixanol and Acute Kidney Failure

ArticleYear
A systematic review of cost-effectiveness analyses across the acute kidney injury landscape.
    Expert review of pharmacoeconomics & outcomes research, 2021, Volume: 21, Issue:4

    Topics: Acute Kidney Injury; Biomarkers; Contrast Media; Cost-Benefit Analysis; Humans; Iohexol; Renal Repla

2021
Economic impact of contrast-induced acute kidney injury associated with invasive cardiology: role of iso-osmolar contrast media in Germany, Italy, Poland, and Spain.
    Journal of medical economics, 2016, Volume: 19, Issue:2

    Topics: Acute Kidney Injury; Coronary Angiography; Europe; Humans; Patient Safety; Percutaneous Coronary Int

2016
Nephrotoxicity of iso-osmolar iodixanol compared with nonionic low-osmolar contrast media: meta-analysis of randomized controlled trials.
    Radiology, 2009, Volume: 250, Issue:1

    Topics: Acute Kidney Injury; Aged; Cardiac Catheterization; Confidence Intervals; Contrast Media; Creatinine

2009
Renal insufficiency following contrast media administration trial II (REMEDIAL II): RenalGuard system in high-risk patients for contrast-induced acute kidney injury: rationale and design.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2011, Volume: 6, Issue:9

    Topics: Acetylcysteine; Acute Kidney Injury; Biomarkers; Chi-Square Distribution; Chronic Disease; Contrast

2011
Cost-effectiveness of iso- versus low-osmolality contrast media in outpatients with high risk of contrast medium-induced nephropathy.
    Biomedica : revista del Instituto Nacional de Salud, 2012, Volume: 32, Issue:2

    Topics: Acute Kidney Injury; Aged; Colombia; Contrast Media; Cost-Benefit Analysis; Decision Trees; Drug Cos

2012
The role of osmolality in the incidence of contrast-induced nephropathy: a systematic review of angiographic contrast media in high risk patients.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Acute Kidney Injury; Contrast Media; Humans; Incidence; Iohexol; Kidney Failure, Chronic; Osmolar Co

2005

Trials

21 trials available for iodixanol and Acute Kidney Failure

ArticleYear
The effect of curcumin in prevention of contrast nephropathy following coronary angiography or angioplasty in CKD patients.
    Iranian journal of kidney diseases, 2019, Volume: 13, Issue:5

    Topics: Acute Kidney Injury; Administration, Oral; Angioplasty; Antioxidants; Contrast Media; Coronary Angio

2019
Nephrotoxicity of iodixanol versus iopamidol in patients undergoing peripheral angiography with or without endovascular therapy.
    International urology and nephrology, 2018, Volume: 50, Issue:10

    Topics: Acute Kidney Injury; Aged; Angiography; Contrast Media; Creatinine; Double-Blind Method; Endovascula

2018
Refining the assessment of contrast-induced acute kidney injury: the load-to-damage relationship.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2014, Volume: 15, Issue:7

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Dose-Response Relations

2014
The prevention of contrast-induced nephropathy by simultaneous hemofiltration during coronary angiographic procedures: a comparison with periprocedural hemofiltration.
    International journal of cardiology, 2014, Oct-20, Volume: 176, Issue:3

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine; Female; Hemofiltration;

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Intravascular ultrasound guidance to minimize the use of iodine contrast in percutaneous coronary intervention: the MOZART (Minimizing cOntrast utiliZation With IVUS Guidance in coRonary angioplasTy) randomized controlled trial.
    JACC. Cardiovascular interventions, 2014, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Coronary Artery Disease

2014
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
    Circulation. Cardiovascular interventions, 2015, Volume: 8, Issue:9

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar

2015
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
    Circulation. Cardiovascular interventions, 2015, Volume: 8, Issue:9

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar

2015
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
    Circulation. Cardiovascular interventions, 2015, Volume: 8, Issue:9

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar

2015
Neutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
    Circulation. Cardiovascular interventions, 2015, Volume: 8, Issue:9

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Aged; Aged, 80 and over; Angiography; Angioplasty; Biomar

2015
Prevention of contrast-induced nephropathy with single bolus erythropoietin in patients with diabetic kidney disease: A randomized controlled trial.
    Nephrology (Carlton, Vic.), 2016, Volume: 21, Issue:4

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Aged, 80 and over; Biomarkers; Contrast Media; Coronary A

2016
Acute Kidney Injury With the RenalGuard System in Patients Undergoing Transcatheter Aortic Valve Replacement: The PROTECT-TAVI Trial (PROphylactic effecT of furosEmide-induCed diuresis with matched isotonic intravenous hydraTion in Transcatheter Aortic Va
    JACC. Cardiovascular interventions, 2015, Volume: 8, Issue:12

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Aortic Valve; Aortic Valve Stenosis; Cardiac Catheteri

2015
One-year results of the ICON (Ionic versus non-ionic Contrast to Obviate worsening Nephropathy after angioplasty in chronic renal failure patients) Study.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2016, Volume: 87, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Contrast Media; Corona

2016
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
    Journal of the American Heart Association, 2016, Mar-15, Volume: 5, Issue:3

    Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont

2016
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
    Journal of the American Heart Association, 2016, Mar-15, Volume: 5, Issue:3

    Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont

2016
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
    Journal of the American Heart Association, 2016, Mar-15, Volume: 5, Issue:3

    Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont

2016
Short-Term High-Dose Vitamin E to Prevent Contrast Medium-Induced Acute Kidney Injury in Patients With Chronic Kidney Disease Undergoing Elective Coronary Angiography: A Randomized Placebo-Controlled Trial.
    Journal of the American Heart Association, 2016, Mar-15, Volume: 5, Issue:3

    Topics: Acute Kidney Injury; Aged; alpha-Tocopherol; Antioxidants; Biomarkers; Chi-Square Distribution; Cont

2016
A prospective, double-blind, randomized, controlled trial on the efficacy and cardiorenal safety of iodixanol vs. iopromide in patients with chronic kidney disease undergoing coronary angiography with or without percutaneous coronary intervention.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2008, Dec-01, Volume: 72, Issue:7

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Cardiovascular Diseases; Contrast Media;

2008
Comparison of iodixanol and iohexol in patients undergoing intravenous pyelography: a prospective controlled study.
    Renal failure, 2009, Volume: 31, Issue:3

    Topics: Acute Kidney Injury; Adult; Aged; Contrast Media; Creatinine; Cytokines; Double-Blind Method; Drug E

2009
Contrast-induced nephropathy and long-term adverse events: cause and effect?
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Comorbidity; Contrast Media; Creatinine; Cystatin C; F

2009
Contrast-induced nephropathy and long-term adverse events: cause and effect?
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Comorbidity; Contrast Media; Creatinine; Cystatin C; F

2009
Contrast-induced nephropathy and long-term adverse events: cause and effect?
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Comorbidity; Contrast Media; Creatinine; Cystatin C; F

2009
Contrast-induced nephropathy and long-term adverse events: cause and effect?
    Clinical journal of the American Society of Nephrology : CJASN, 2009, Volume: 4, Issue:7

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Comorbidity; Contrast Media; Creatinine; Cystatin C; F

2009
Sodium bicarbonate plus isotonic saline versus saline for prevention of contrast-induced nephropathy in patients undergoing coronary angiography: a randomized controlled trial.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2009, Volume: 54, Issue:4

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Double-Blin

2009
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
The contrast media and nephrotoxicity following coronary revascularization by primary angioplasty for acute myocardial infarction study: design and rationale of the CONTRAST-AMI study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Angioplasty, Balloon, Coronary; Biomarkers; Contrast Media; Cor

2010
Prevention of contrast-induced acute kidney injury by theophylline in elderly patients with chronic kidney disease.
    Heart and vessels, 2010, Volume: 25, Issue:6

    Topics: Acute Kidney Injury; Age Factors; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Biomarker

2010
High incidence of nephropathy in neurosurgical patients after intra-arterial administration of low-osmolar and iso-osmolar contrast media.
    Acta radiologica (Stockholm, Sweden : 1987), 2011, May-01, Volume: 52, Issue:4

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Diabetes Complications; Double-

2011
Renal insufficiency following contrast media administration trial II (REMEDIAL II): RenalGuard system in high-risk patients for contrast-induced acute kidney injury: rationale and design.
    EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2011, Volume: 6, Issue:9

    Topics: Acetylcysteine; Acute Kidney Injury; Biomarkers; Chi-Square Distribution; Chronic Disease; Contrast

2011
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Impact of iso-osmolar versus low-osmolar contrast agents on contrast-induced nephropathy and tissue reperfusion in unselected patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (from the Contrast
    The American journal of cardiology, 2012, Jan-01, Volume: 109, Issue:1

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Cor

2012
Oral acetylcysteine does not protect renal function from moderate to high doses of intravenous radiographic contrast.
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2003, Volume: 58, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Administration, Oral; Aged; Cardiac Catheterization; Contrast M

2003
Cost-effectiveness of iodixanol in patients at high risk of contrast-induced nephropathy.
    American heart journal, 2005, Volume: 149, Issue:2

    Topics: Acute Kidney Injury; Angiography; Contrast Media; Coronary Angiography; Cost-Benefit Analysis; Healt

2005

Other Studies

66 other studies available for iodixanol and Acute Kidney Failure

ArticleYear
Capsaicin Prevents Contrast-Associated Acute Kidney Injury through Activation of Nrf2 in Mice.
    Oxidative medicine and cellular longevity, 2022, Volume: 2022

    Topics: Acute Kidney Injury; Animals; Capsaicin; Contrast Media; Disease Models, Animal; Kidney; Malondialde

2022
A multiple-metabolites model to predict preliminary renal injury induced by iodixanol based on UHPLC/Q-Orbitrap-MS and
    Metabolomics : Official journal of the Metabolomic Society, 2022, 10-28, Volume: 18, Issue:11

    Topics: Acute Kidney Injury; Biomarkers; Chromatography, High Pressure Liquid; Humans; Indoles; Kidney; Kynu

2022
Iodixanol-associated acute kidney injury and prognosis in patients undergoing elective percutaneous coronary intervention: a prospective, multi-center study.
    European radiology, 2023, Volume: 33, Issue:12

    Topics: Acute Kidney Injury; Aged; Contrast Media; Humans; Myocardial Infarction; Percutaneous Coronary Inte

2023
Dosing of iodixanol for predicting acute kidney injury in patients undergoing elective percutaneous coronary intervention.
    European journal of internal medicine, 2023, Volume: 118

    Topics: Acute Kidney Injury; Contrast Media; Creatinine; Humans; Percutaneous Coronary Intervention; Risk Fa

2023
APELA/ELA32 Reduces Iodixanol-induced Apoptosis, Inflammatory Response and Mitochondrial and DNA Damage in Renal Tubular Epithelial Cells.
    Anticancer research, 2020, Volume: 40, Issue:2

    Topics: Acute Kidney Injury; Apoptosis; Contrast Media; DNA Damage; Epithelial Cells; Humans; Kidney; Mitoch

2020
Subclinical Contrast-Induced Acute Kidney Injury in Patients Undergoing Cerebral Computed Tomography.
    Cardiorenal medicine, 2020, Volume: 10, Issue:2

    Topics: Acute Kidney Injury; Aged; Biomarkers; Brain; Contrast Media; Creatinine; Female; Glomerular Filtrat

2020
Increased fibrotic signaling in a murine model for intra-arterial contrast-induced acute kidney injury.
    American journal of physiology. Renal physiology, 2020, 05-01, Volume: 318, Issue:5

    Topics: Acute Kidney Injury; Animals; Apoptosis; Carotid Arteries; Cell Hypoxia; Cell Proliferation; Collage

2020
Incidence of contrast-induced acute kidney injury (CI-AKI) in high-risk oncology patients undergoing contrast-enhanced CT with a reduced dose of the iso-osmolar iodinated contrast medium iodixanol.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Incidence; Male

2020
Rapamycin improves renal injury induced by Iodixanol in diabetic rats by deactivating the mTOR/p70S6K signaling pathway.
    Life sciences, 2020, Oct-15, Volume: 259

    Topics: Acute Kidney Injury; Animals; Apoptosis; Autophagy; Diabetes Mellitus, Experimental; Kidney; Male; P

2020
Effects of a High Dose of the Contrast Medium Iodixanol on Renal Function in Patients Following Percutaneous Coronary Intervention.
    Angiology, 2021, Volume: 72, Issue:2

    Topics: Acute Kidney Injury; Aged; Contrast Media; Female; Glomerular Filtration Rate; Humans; Incidence; Ma

2021
Rho Kinase Inhibitor, Fasudil, Attenuates Contrast-induced Acute Kidney Injury.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 122, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acute Kidney Injury; Animals; Apoptosis; Biomarkers;

2018
Predictors and Outcomes of Postcontrast Acute Kidney Injury after Endovascular Renal Artery Intervention.
    Journal of vascular and interventional radiology : JVIR, 2017, Volume: 28, Issue:12

    Topics: Acute Kidney Injury; Aged; Computed Tomography Angiography; Contrast Media; Female; Follow-Up Studie

2017
The effect of major adverse renal cardiovascular event (MARCE) incidence, procedure volume, and unit cost on the hospital savings resulting from contrast media use in inpatient angioplasty.
    Journal of medical economics, 2018, Volume: 21, Issue:4

    Topics: Acute Kidney Injury; Angioplasty; Budgets; Contrast Media; Costs and Cost Analysis; Female; Heart Di

2018
Major Adverse Renal and Cardiac Events After Coronary Angiography and Cardiac Surgery.
    The Annals of thoracic surgery, 2018, Volume: 105, Issue:6

    Topics: Acute Kidney Injury; Aged; Cardiac Surgical Procedures; Cohort Studies; Confidence Intervals; Contra

2018
Mitophagy Plays a Protective Role in Iodinated Contrast-Induced Acute Renal Tubular Epithelial Cells Injury.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2018, Volume: 46, Issue:3

    Topics: Acute Kidney Injury; Adenine; Apoptosis; Autophagy; Cell Line; Contrast Media; Epithelial Cells; Hum

2018
Are iso-osmolar, as compared to low-osmolar, contrast media cost-effective in patients undergoing cardiac catheterization? An economic analysis.
    International urology and nephrology, 2018, Volume: 50, Issue:8

    Topics: Acute Kidney Injury; Canada; Cardiac Catheterization; Contrast Media; Coronary Angiography; Cost-Ben

2018
Comparison of iohexol and iodixanol induced nephrotoxicity, mitochondrial damage and mitophagy in a new contrast-induced acute kidney injury rat model.
    Archives of toxicology, 2018, Volume: 92, Issue:7

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Kidney Function Tests

2018
Incidence of contrast-induced acute kidney injury in a large cohort of all-comers undergoing percutaneous coronary intervention: Comparison of five contrast media.
    International journal of cardiology, 2018, Dec-15, Volume: 273

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Cohort Studies; Contrast Media; Female; Humans; Incide

2018
Acute effects of Iodixanol on renal function after intra-arterial administration in patients with end-stage kidney disease.
    Clinical hemorheology and microcirculation, 2018, Volume: 70, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Contrast Media; Female; Humans; Kidney Failure, Chroni

2018
Long-term renal outcomes and mortality following renal injury among myocardial infarction patients treated by primary percutaneous intervention.
    Coronary artery disease, 2019, Volume: 30, Issue:2

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Comorbidity; Contrast Media; Creatinine; Disease Progr

2019
Low incidence of nephrotoxicity following intravenous administration of iodinated contrast media: a prospective study.
    European radiology, 2019, Volume: 29, Issue:7

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Contrast Media; Female; Glomerular Filtratio

2019
Evaluation of iodine contrast-induced acute kidney injury via different injection routes using BOLD-MRI.
    Renal failure, 2019, Volume: 41, Issue:1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Ear Auricle; Femoral Artery; H

2019
Blood Oxygen Level-Dependent Imaging and Intravoxel Incoherent Motion MRI of Early Contrast-Induced Acute Kidney Injury in a Rabbit Model.
    Kidney & blood pressure research, 2019, Volume: 44, Issue:4

    Topics: Acute Kidney Injury; Animals; Contrast Media; Diffusion Magnetic Resonance Imaging; Disease Models,

2019
Effect of iodinated contrast media on the oxygen tension in the renal cortico-medullary region of pigs.
    Clinical hemorheology and microcirculation, 2019, Volume: 73, Issue:1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Hemodynamics; Male; Microcirculation; Swine; Triiodobe

2019
Renal function following fistulography in patients with advanced chronic kidney disease.
    Renal failure, 2013, Volume: 35, Issue:6

    Topics: Acute Kidney Injury; Aged; Angiography; Arteriovenous Shunt, Surgical; Contrast Media; Glomerular Fi

2013
Low-dose nitrite alleviates early effects of an X-ray contrast medium on renal hemodynamics and oxygenation in rats.
    Investigative radiology, 2014, Volume: 49, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Flow Velocity; Contrast Media; Dose-Response Relationship, Drug;

2014
Exposure to low- vs iso-osmolar contrast agents reduces NADPH-dependent reactive oxygen species generation in a cellular model of renal injury.
    Free radical biology & medicine, 2014, Volume: 68

    Topics: Acute Kidney Injury; Apoptosis; Contrast Media; Humans; Iohexol; Iopamidol; Kidney; NADP; NADPH Oxid

2014
Iodinated contrast media cause direct tubular cell damage, leading to oxidative stress, low nitric oxide, and impairment of tubuloglomerular feedback.
    American journal of physiology. Renal physiology, 2014, Apr-15, Volume: 306, Issue:8

    Topics: Acute Kidney Injury; Animals; Biological Availability; Cell Death; Contrast Media; Feedback, Physiol

2014
Pre-procedural bioimpedance vectorial analysis of fluid status and prediction of contrast-induced acute kidney injury.
    Journal of the American College of Cardiology, 2014, Apr-15, Volume: 63, Issue:14

    Topics: Acute Kidney Injury; Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Artery Dis

2014
Pre-procedural bioimpedance vectorial analysis of fluid status and prediction of contrast-induced acute kidney injury.
    Journal of the American College of Cardiology, 2014, Apr-15, Volume: 63, Issue:14

    Topics: Acute Kidney Injury; Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Artery Dis

2014
Pre-procedural bioimpedance vectorial analysis of fluid status and prediction of contrast-induced acute kidney injury.
    Journal of the American College of Cardiology, 2014, Apr-15, Volume: 63, Issue:14

    Topics: Acute Kidney Injury; Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Artery Dis

2014
Pre-procedural bioimpedance vectorial analysis of fluid status and prediction of contrast-induced acute kidney injury.
    Journal of the American College of Cardiology, 2014, Apr-15, Volume: 63, Issue:14

    Topics: Acute Kidney Injury; Aged; Cohort Studies; Contrast Media; Coronary Angiography; Coronary Artery Dis

2014
Evaluation of intrarenal oxygenation in iodinated contrast-induced acute kidney injury-susceptible rats by blood oxygen level-dependent magnetic resonance imaging.
    Investigative radiology, 2014, Volume: 49, Issue:6

    Topics: Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Feasibility Studies;

2014
Efficacy of preventive interventions for iodinated contrast-induced acute kidney injury evaluated by intrarenal oxygenation as an early marker.
    Investigative radiology, 2014, Volume: 49, Issue:10

    Topics: Acetylcysteine; Acute Kidney Injury; Acute-Phase Proteins; Animals; Biomarkers; Contrast Media; Dise

2014
Significant perturbation in renal functional magnetic resonance imaging parameters and contrast retention for iodixanol compared with iopromide: an experimental study using blood-oxygen-level-dependent/diffusion-weighted magnetic resonance imaging and com
    Investigative radiology, 2014, Volume: 49, Issue:11

    Topics: Acute Kidney Injury; Analysis of Variance; Animals; Contrast Media; Diffusion Magnetic Resonance Ima

2014
Extended renal outcomes with use of iodixanol versus iohexol after coronary angiography.
    BioMed research international, 2014, Volume: 2014

    Topics: Acute Kidney Injury; Age Distribution; Aged; Cohort Studies; Contrast Media; Coronary Angiography; F

2014
Incidence of acute kidney injury after intravenous administration of iodixanol for computed tomographic angiography.
    International journal of cardiology, 2014, Dec-20, Volume: 177, Issue:3

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Cohort Studies; Coronary Angiography; Female

2014
Intravenous contrast material exposure is not an independent risk factor for dialysis or mortality.
    Radiology, 2014, Volume: 273, Issue:3

    Topics: Acute Kidney Injury; Aged; Contrast Media; Electronic Health Records; Female; Humans; Injections, In

2014
Diadenosine pentaphosphate modulates glomerular arteriolar tone and glomerular filtration rate.
    Acta physiologica (Oxford, England), 2015, Volume: 213, Issue:1

    Topics: Acute Kidney Injury; Animals; Arterioles; Dinucleoside Phosphates; Glomerular Filtration Rate; Kidne

2015
A novel contrast-induced acute kidney injury model based on the 5/6-nephrectomy rat and nephrotoxicological evaluation of iohexol and iodixanol in vivo.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Acute Kidney Injury; Animals; Contrast Media; Disease Models, Animal; Iohexol; Kidney; Male; Nephrec

2014
The risk of acute kidney injury with transjugular intrahepatic portosystemic shunts.
    Journal of nephrology, 2015, Volume: 28, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Contrast Media; Creatinine; Female; Humans;

2015
Evaluation of urine fibrinogen level in a murine model of contrast-induced nephropathy.
    Vascular, 2016, Volume: 24, Issue:3

    Topics: Acute Kidney Injury; Animals; Biomarkers; Creatinine; Disease Models, Animal; Early Diagnosis; Fibri

2016
[Contrast-induced acute kidney injury after primary percutaneous coronary interventions: Prevalence, predictive factors, and outcomes].
    Terapevticheskii arkhiv, 2015, Volume: 87, Issue:6

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Contrast Media; Electr

2015
The incidence and significance of acute kidney injury following emergent contrast administration in patients with STEMI and stroke.
    Internal and emergency medicine, 2016, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Administration, Intravenous; Aged; Cohort Studies; Contrast Media; Creatinine;

2016
Role of Neutrophil Gelatinase-associated Lipocalin in the Detection of Contrast-induced Nephropathy in Patients Undergoing a Coronary Angiography.
    Revista espanola de cardiologia (English ed.), 2016, Volume: 69, Issue:5

    Topics: Acute Coronary Syndrome; Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Creatinine

2016
Acute kidney damage induced by low- and iso-osmolar contrast media in rats: Comparison study with physiologic MRI and histologic-gene examination.
    Journal of magnetic resonance imaging : JMRI, 2017, Volume: 45, Issue:1

    Topics: Acute Kidney Injury; Animals; Contrast Media; Dose-Response Relationship, Drug; Magnetic Resonance I

2017
Incidences of acute kidney injury, dialysis, and graft loss following intravenous administration of low-osmolality iodinated contrast in patients with kidney transplants.
    Abdominal radiology (New York), 2016, Volume: 41, Issue:11

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Contrast Media; Female; Glomerular

2016
Gender Difference in the Risk of Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography or Percutaneous Coronary Intervention.
    Angiology, 2017, Volume: 68, Issue:6

    Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Female; Humans; Incidence; Iohexol;

2017
A Novel Technique to Reduce Contrast Exposure During Subclavian Interventions.
    Vascular and endovascular surgery, 2017, Volume: 51, Issue:2

    Topics: Acute Kidney Injury; Aged; Angiography, Digital Subtraction; Angioplasty, Balloon; Arterial Occlusiv

2017
Contrast-induced acute kidney injury in renal transplant recipients after cardiac catheterization.
    Clinical nephrology, 2009, Volume: 71, Issue:6

    Topics: Acute Kidney Injury; Cardiac Catheterization; Contrast Media; Creatinine; Female; Humans; Incidence;

2009
Comment on meta-analyses of trials comparing contrast media.
    Radiology, 2009, Volume: 252, Issue:1

    Topics: Acute Kidney Injury; Aged; Cardiac Catheterization; Confidence Intervals; Contrast Media; Creatinine

2009
Preprocedural score for risk of contrast-induced nephropathy in elective coronary angiography and intervention.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2010, Volume: 11, Issue:6

    Topics: Acute Kidney Injury; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Coronary Angiography; Fem

2010
Effect of contrast-induced nephropathy on cardiac outcomes after use of nonionic isosmolar contrast media during coronary procedure.
    Journal of cardiology, 2010, Volume: 56, Issue:3

    Topics: Acute Kidney Injury; Aged; Biomarkers; Contrast Media; Coronary Angiography; Creatinine; Female; Hem

2010
The relative renal safety of iodixanol and low-osmolar contrast media in patients undergoing percutaneous coronary intervention. Insights from Blue Cross Blue Shield of Michigan Cardiovascular Consortium (BMC2).
    The Journal of invasive cardiology, 2010, Volume: 22, Issue:10

    Topics: Acute Kidney Injury; Angioplasty, Balloon, Coronary; Contrast Media; Female; Humans; Male; Osmolar C

2010
Contrast medium-induced acute kidney injury: comparison of intravenous and intraarterial administration of iodinated contrast medium.
    Journal of vascular and interventional radiology : JVIR, 2011, Volume: 22, Issue:8

    Topics: Acute Kidney Injury; Aged; Angiography, Digital Subtraction; Arterial Occlusive Diseases; Chi-Square

2011
Impact of contrast-induced acute kidney injury with transient or persistent renal dysfunction on long-term outcomes of patients with acute myocardial infarction undergoing percutaneous coronary intervention.
    Heart (British Cardiac Society), 2011, Volume: 97, Issue:21

    Topics: Acute Kidney Injury; Adult; Aged; Angioplasty, Balloon, Coronary; Contrast Media; Disease Progressio

2011
The osmolality of nonionic, iodinated contrast agents as an important factor for renal safety.
    Investigative radiology, 2012, Volume: 47, Issue:9

    Topics: Acute Kidney Injury; Animals; Biomarkers; Contrast Media; Iohexol; Kidney; Male; Mannitol; Osmolar C

2012
Effect of renin-angiotensin-aldosterone system blockade therapy on incidence of contrast-induced nephropathy in patients with chronic kidney disease.
    Iranian journal of kidney diseases, 2012, Volume: 6, Issue:6

    Topics: Acute Kidney Injury; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme In

2012
Effect of low-osmolar contrast medium iopromide and iso-osmolar iodixanol on DNA fragmentation in renal tubular cell culture.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:6

    Topics: Acute Kidney Injury; Cell Line; Contrast Media; DNA Fragmentation; Humans; Iohexol; Kidney; Osmolar

2013
Protection from contrast-induced nephropathy: is the answer in?
    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2003, Volume: 58, Issue:3

    Topics: Acetylcysteine; Acute Kidney Injury; Cardiac Catheterization; Contrast Media; Free Radical Scavenger

2003
Contrast nephropathy post cardiac resynchronization therapy: an under-recognized complication with important morbidity.
    European journal of heart failure, 2005, Volume: 7, Issue:5

    Topics: Acute Kidney Injury; Aged; Cardiac Pacing, Artificial; Contrast Media; Creatinine; Defibrillators, I

2005
Contrast dose-to-creatinine clearance ratio as a potential indicator of risk for radiocontrast-induced nephropathy: correlation of D/CrCL with area under the contrast concentration-time curve using iodixanol.
    Investigative radiology, 2005, Volume: 40, Issue:9

    Topics: Acute Kidney Injury; Area Under Curve; Chromatography, High Pressure Liquid; Contrast Media; Creatin

2005
Nephrotoxicity of low-osmolality versus iso-osmolality contrast agents: impact of N-acetylcysteine.
    Kidney international, 2005, Volume: 68, Issue:5

    Topics: Acetylcysteine; Acute Kidney Injury; Aged; Contrast Media; Female; Fluid Therapy; Humans; Iohexol; K

2005
Contrast-induced nephropathy in urgent coronary interventions.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2006, Volume: 7, Issue:10

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Analysis of Variance; Angioplasty, Balloon, Coronary;

2006
Visipaque (iodixanol) and hexabrix (ioxaglate) in renal insufficiency.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Incidence; Ioxa

2007
Evaluation and comparison between visipaque (iodixanol) and hexabrix (ioxaglate) in coronary angiography.
    Journal of the American College of Cardiology, 2007, Apr-17, Volume: 49, Issue:15

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Coronary Disease; Humans; Ioxaglic Acid;

2007
Acute renal haemodynamic effects of radiocontrast media in patients undergoing left ventricular and coronary angiography.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:5

    Topics: Acute Kidney Injury; Aged; Blood Flow Velocity; Contrast Media; Coronary Angiography; Creatinine; Fe

2008
Influence of the timing of cardiac catheterization and the amount of contrast media on acute renal failure after cardiac surgery.
    The American journal of cardiology, 2008, Apr-15, Volume: 101, Issue:8

    Topics: Acute Kidney Injury; Age Factors; Aged; Cardiac Catheterization; Cardiac Surgical Procedures; Cardio

2008
Renal effects of iodixanol in healthy volunteers and patients with severe renal failure.
    Acta radiologica. Supplementum, 1995, Volume: 399

    Topics: Acute Kidney Injury; Contrast Media; Glomerular Filtration Rate; Humans; Kidney; Kidney Failure, Chr

1995