Page last updated: 2024-10-18

iodine and Premature Birth

iodine has been researched along with Premature Birth in 18 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Premature Birth: CHILDBIRTH before 37 weeks of PREGNANCY (259 days from the first day of the mother's last menstrual period, or 245 days after FERTILIZATION).

Research Excerpts

ExcerptRelevanceReference
" Maternal primary outcomesIodine supplementation decreased the likelihood of the adverse effect of postpartum hyperthyroidism by 68% (average risk ratio (RR) 0."8.95Iodine supplementation for women during the preconception, pregnancy and postpartum period. ( De-Regil, LM; Harding, KB; Ota, E; Payne, BA; Peña-Rosas, JP; Webster, AC; Yap, CM, 2017)
"Severe iodine deficiency during gestation is associated with adverse pregnancy outcomes; however, the impact of mild-to-moderate iodine deficiency, though prevalent in pregnancy, remains unclear."8.12No Association Was Found Between Mild Iodine Deficiency During Pregnancy and Pregnancy Outcomes: a Follow-up Study Based on a Birth Registry. ( Cui, X; Guo, C; Jin, W; Shi, Z; Song, Q; Tang, H; Wang, H; Wang, Z; Yu, H; Zang, J, 2022)
"Iodine deficiency in pregnant women can be improved by appreciate planning for pregnancy, proper inter-pregnancy time interval (> 12 months to < 5 years), appropriate nutrition during pregnancy."7.96Maternal and neonatal outcomes and determinants of iodine deficiency in third trimester of pregnancy in an iodine sufficient area. ( Bakhshali-Bakhtiari, M; Bakhtiyari, M; Fateh, R; Gargari, SS; Mirzamoradi, M; Saleh, M, 2020)
"Normal maternal thyroid function during pregnancy is essential for fetal development and depends upon an adequate supply of iodine."7.91The Joint Role of Thyroid Function and Iodine Status on Risk of Preterm Birth and Small for Gestational Age: A Population-Based Nested Case-Control Study of Finnish Women. ( Bell, GA; Gissler, M; Kannan, K; Kim, UJ; Liu, A; Männistö, T; Mills, JL; Mumford, SL; Purdue-Smithe, AC; Surcel, HM; Suvanto, E, 2019)
"This study aimed to assess the iodine status of pregnant women in each trimester and to compare the pregnancy outcomes between groups with iodine insufficiency and iodine sufficiency."7.83Maternal iodine insufficiency and adverse pregnancy outcomes. ( Charoenratana, C; Leelapat, P; Tongsong, T; Traisrisilp, K, 2016)
"Iodine is an essential macronutrient for feto-maternal growth and development."6.66Maternal Urinary Iodine Concentration and Pregnancy Outcomes in Euthyroid Pregnant Women: a Systematic Review and Meta-analysis. ( Azizi, F; Behboudi-Gandevani, S; Bidhendi Yarandi, R; Nazarpour, S; Ramezani Tehrani, F, 2020)
"Background & aims: Iodine is important for thyroid function during pregnancy to support fetal growth, but studies of maternal iodine status and birth outcomes are conflicting."5.41Maternal Iodine Status and Birth Outcomes: A Systematic Literature Review and Meta-Analysis. ( Greenwood, DC; Hardie, LJ; Keeble, C; Taylor, E; Webster, J, 2023)
" Maternal primary outcomesIodine supplementation decreased the likelihood of the adverse effect of postpartum hyperthyroidism by 68% (average risk ratio (RR) 0."4.95Iodine supplementation for women during the preconception, pregnancy and postpartum period. ( De-Regil, LM; Harding, KB; Ota, E; Payne, BA; Peña-Rosas, JP; Webster, AC; Yap, CM, 2017)
"92 mIU/L; these women may benefit from Levothyroxine (LT4) therapy for preventing preterm birth."4.31A Bayesian model to estimate the cutoff value of TSH for management of preterm birth. ( Azizi, F; Behboudi-Gandevani, S; Minooee, S; Nazarpour, S; Rahmati, M; Tehrani, FR, 2023)
"Severe iodine deficiency during gestation is associated with adverse pregnancy outcomes; however, the impact of mild-to-moderate iodine deficiency, though prevalent in pregnancy, remains unclear."4.12No Association Was Found Between Mild Iodine Deficiency During Pregnancy and Pregnancy Outcomes: a Follow-up Study Based on a Birth Registry. ( Cui, X; Guo, C; Jin, W; Shi, Z; Song, Q; Tang, H; Wang, H; Wang, Z; Yu, H; Zang, J, 2022)
"Iodine deficiency in pregnant women can be improved by appreciate planning for pregnancy, proper inter-pregnancy time interval (> 12 months to < 5 years), appropriate nutrition during pregnancy."3.96Maternal and neonatal outcomes and determinants of iodine deficiency in third trimester of pregnancy in an iodine sufficient area. ( Bakhshali-Bakhtiari, M; Bakhtiyari, M; Fateh, R; Gargari, SS; Mirzamoradi, M; Saleh, M, 2020)
"Normal maternal thyroid function during pregnancy is essential for fetal development and depends upon an adequate supply of iodine."3.91The Joint Role of Thyroid Function and Iodine Status on Risk of Preterm Birth and Small for Gestational Age: A Population-Based Nested Case-Control Study of Finnish Women. ( Bell, GA; Gissler, M; Kannan, K; Kim, UJ; Liu, A; Männistö, T; Mills, JL; Mumford, SL; Purdue-Smithe, AC; Surcel, HM; Suvanto, E, 2019)
"The isolated hypothyroxinemia of pregnancy (IHP) has gained specific attention in the specialized literature during the recent years as the possible factor impeding the intellectual development of fetus and increasing the risk of complications related with pregnancy, delivery and perinatal period."3.88IMPORTANCE OF ISOLATED GESTATIONAL HYPOTHYROXINEMIA IN THE DEVELOPMENT OF OBSTETRIC AND SOMATIC PATHOLOGIES. ( Gagua, D; Gagua, T; Morchiladze, N; Tkeshelashvili, B, 2018)
"This study aimed to assess the iodine status of pregnant women in each trimester and to compare the pregnancy outcomes between groups with iodine insufficiency and iodine sufficiency."3.83Maternal iodine insufficiency and adverse pregnancy outcomes. ( Charoenratana, C; Leelapat, P; Tongsong, T; Traisrisilp, K, 2016)
"Pregnancy is a complex state with many endocrinological challenges to a woman's physiology."2.72Understanding the Pathogenesis of Gestational Hypothyroidism. ( Li, X; Mallawa Kankanamalage, O; Zhou, Q, 2021)
"Iodine is an essential macronutrient for feto-maternal growth and development."2.66Maternal Urinary Iodine Concentration and Pregnancy Outcomes in Euthyroid Pregnant Women: a Systematic Review and Meta-analysis. ( Azizi, F; Behboudi-Gandevani, S; Bidhendi Yarandi, R; Nazarpour, S; Ramezani Tehrani, F, 2020)
"If left untreated, both hypothyroidism and hyperthyroidism are associated with adverse effects on pregnancy and fetal outcomes."2.48Thyroid disorders during pregnancy. ( Sullivan, SD; Yazbeck, CF, 2012)
"Overt thyrotoxicosis has to be treated with propylthiouracil, to maintain euthyroidism during pregnancy."2.45[Thyroid disorders during pregnancy]. ( Gärtner, R, 2009)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (11.11)29.6817
2010's9 (50.00)24.3611
2020's7 (38.89)2.80

Authors

AuthorsStudies
Cui, X1
Yu, H1
Wang, Z1
Wang, H1
Shi, Z1
Jin, W1
Song, Q1
Guo, C1
Tang, H1
Zang, J1
Nazarpour, S3
Ramezani Tehrani, F2
Amiri, M1
Rahmati, M2
Azizi, F3
Greenwood, DC2
Webster, J1
Keeble, C2
Taylor, E2
Hardie, LJ2
Minooee, S1
Behboudi-Gandevani, S2
Tehrani, FR1
Purdue-Smithe, AC1
Männistö, T1
Bell, GA1
Mumford, SL1
Liu, A1
Kannan, K1
Kim, UJ1
Suvanto, E1
Surcel, HM1
Gissler, M1
Mills, JL1
Bidhendi Yarandi, R1
Gargari, SS1
Fateh, R1
Bakhshali-Bakhtiari, M1
Saleh, M1
Mirzamoradi, M1
Bakhtiyari, M1
Mallawa Kankanamalage, O1
Zhou, Q1
Li, X1
Morchiladze, N1
Tkeshelashvili, B1
Gagua, T1
Gagua, D1
Snart, CJP1
Cade, JE1
Stewart, PM1
Zimmermann, M1
Reid, S1
Threapleton, DE1
Poston, L1
Myers, JE1
Simpson, NAB1
Korevaar, TI1
Schalekamp-Timmermans, S1
de Rijke, YB1
Visser, WE1
Visser, W1
de Muinck Keizer-Schrama, SM1
Hofman, A1
Ross, HA1
Hooijkaas, H1
Tiemeier, H1
Bongers-Schokking, JJ1
Jaddoe, VW1
Visser, TJ1
Steegers, EA1
Medici, M1
Peeters, RP1
León, G1
Murcia, M1
Rebagliato, M1
Álvarez-Pedrerol, M1
Castilla, AM1
Basterrechea, M1
Iñiguez, C1
Fernández-Somoano, A1
Blarduni, E1
Foradada, CM1
Tardón, A1
Vioque, J1
Bliddal, S1
Boas, M1
Hilsted, L1
Friis-Hansen, L1
Tabor, A1
Feldt-Rasmussen, U1
Charoenratana, C1
Leelapat, P1
Traisrisilp, K1
Tongsong, T1
Harding, KB1
Peña-Rosas, JP1
Webster, AC1
Yap, CM1
Payne, BA1
Ota, E1
De-Regil, LM1
Gärtner, R1
Sen'kevich, OA1
Sirotina, ZV1
Koval'skiĭ, IuG1
Golik, LS1
Yazbeck, CF1
Sullivan, SD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessing Iodine Status and Associated Health Outcomes in British Women During Pregnancy[NCT03552341]246 participants (Actual)Observational2016-02-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for iodine and Premature Birth

ArticleYear
Maternal Iodine Status and Birth Outcomes: A Systematic Literature Review and Meta-Analysis.
    Nutrients, 2023, Jan-12, Volume: 15, Issue:2

    Topics: Birth Weight; Female; Fetal Development; Fetal Growth Retardation; Humans; Infant, Newborn; Iodides;

2023
Maternal Urinary Iodine Concentration and Pregnancy Outcomes in Euthyroid Pregnant Women: a Systematic Review and Meta-analysis.
    Biological trace element research, 2020, Volume: 197, Issue:2

    Topics: Birth Weight; Female; Humans; Infant, Newborn; Iodine; Pregnancy; Pregnancy Complications; Pregnancy

2020
Understanding the Pathogenesis of Gestational Hypothyroidism.
    Frontiers in endocrinology, 2021, Volume: 12

    Topics: Abortion, Spontaneous; Abruptio Placentae; Animals; Estrogens; Female; Fetal Death; Humans; Hypothyr

2021
Iodine supplementation for women during the preconception, pregnancy and postpartum period.
    The Cochrane database of systematic reviews, 2017, 03-05, Volume: 3

    Topics: Dietary Supplements; Female; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn; Infant, Newbo

2017
[Thyroid disorders during pregnancy].
    Deutsche medizinische Wochenschrift (1946), 2009, Volume: 134, Issue:3

    Topics: Abortion, Spontaneous; Female; Fetal Diseases; Graves Disease; Humans; Hyperthyroidism; Hypothyroidi

2009
Thyroid disorders during pregnancy.
    The Medical clinics of North America, 2012, Volume: 96, Issue:2

    Topics: Abortion, Spontaneous; Diet; Female; Hormone Replacement Therapy; Humans; Hypothyroidism; Iodine; Ma

2012

Other Studies

12 other studies available for iodine and Premature Birth

ArticleYear
No Association Was Found Between Mild Iodine Deficiency During Pregnancy and Pregnancy Outcomes: a Follow-up Study Based on a Birth Registry.
    Biological trace element research, 2022, Volume: 200, Issue:10

    Topics: Cesarean Section; China; Cohort Studies; Female; Follow-Up Studies; Humans; Infant, Newborn; Iodides

2022
Maternal subclinical hyperthyroidism and adverse pregnancy outcomes considering the iodine status: Tehran thyroid and pregnancy study.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2022, Volume: 74

    Topics: Female; Humans; Hyperthyroidism; Infant, Newborn; Iodide Peroxidase; Iodides; Iodine; Iran; Pregnanc

2022
A Bayesian model to estimate the cutoff value of TSH for management of preterm birth.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Bayes Theorem; Female; Humans; Infant, Newborn; Iodide Peroxidase; Iodine; Iran; Pregnancy; Prematur

2023
The Joint Role of Thyroid Function and Iodine Status on Risk of Preterm Birth and Small for Gestational Age: A Population-Based Nested Case-Control Study of Finnish Women.
    Nutrients, 2019, Oct-25, Volume: 11, Issue:11

    Topics: Adult; Case-Control Studies; Female; Finland; Gestational Age; Humans; Infant, Newborn; Infant, Smal

2019
Maternal and neonatal outcomes and determinants of iodine deficiency in third trimester of pregnancy in an iodine sufficient area.
    BMC pregnancy and childbirth, 2020, Mar-18, Volume: 20, Issue:1

    Topics: Adult; Cross-Sectional Studies; Dietary Supplements; Female; Humans; Infant, Newborn; Infant, Newbor

2020
IMPORTANCE OF ISOLATED GESTATIONAL HYPOTHYROXINEMIA IN THE DEVELOPMENT OF OBSTETRIC AND SOMATIC PATHOLOGIES.
    Georgian medical news, 2018, Issue:278

    Topics: Abortion, Spontaneous; Adolescent; Adult; Alopecia; Case-Control Studies; Diabetes Mellitus; Female;

2018
Maternal Iodine Status and Associations with Birth Outcomes in Three Major Cities in the United Kingdom.
    Nutrients, 2019, Feb-20, Volume: 11, Issue:2

    Topics: Adult; Birth Weight; Cities; Female; Gestational Age; Humans; Infant, Newborn; Infant, Small for Ges

2019
Hypothyroxinemia and TPO-antibody positivity are risk factors for premature delivery: the generation R study.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:11

    Topics: Adult; Autoantibodies; Female; Fetal Membranes, Premature Rupture; Humans; Hyperthyroidism; Hypothyr

2013
Maternal thyroid dysfunction during gestation, preterm delivery, and birthweight. The Infancia y Medio Ambiente Cohort, Spain.
    Paediatric and perinatal epidemiology, 2015, Volume: 29, Issue:2

    Topics: Adult; Birth Weight; Female; Gestational Age; Humans; Hypothyroidism; Infant, Newborn; Iodine; Mothe

2015
Thyroid function and autoimmunity in Danish pregnant women after an iodine fortification program and associations with obstetric outcomes.
    European journal of endocrinology, 2015, Volume: 173, Issue:6

    Topics: Adult; Autoantibodies; Autoimmunity; Cohort Studies; Denmark; Female; Food, Fortified; Gestational A

2015
Maternal iodine insufficiency and adverse pregnancy outcomes.
    Maternal & child nutrition, 2016, Volume: 12, Issue:4

    Topics: Adult; Dietary Supplements; Female; Fetal Growth Retardation; Humans; Iodine; Logistic Models; Longi

2016
[Iodine content in breast milk of nursing mother in norme and premature birth].
    Voprosy pitaniia, 2008, Volume: 77, Issue:6

    Topics: Breast Feeding; Dietary Supplements; Female; Humans; Infant, Newborn; Iodine; Maternal Nutritional P

2008