Page last updated: 2024-10-18

iodine and Parkinson Disease

iodine has been researched along with Parkinson Disease in 15 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Research Excerpts

ExcerptRelevanceReference
"A prospective study including 19 Parkinson's disease and 12 multiple system atrophy patients was performed."1.72Cardiac sympathetic innervation in Parkinson's disease versus multiple system atrophy. ( Bösch, S; Djamshidian, A; Donnemiller, E; Eckhardt, C; Eschlböck, S; Fanciulli, A; Kiechl, S; Krismer, F; Mair, K; Metzler, B; Poewe, W; Raccagni, C; Scherfler, C; Seppi, K; Uprimny, C; Virgolini, I; Wenning, GK, 2022)
" In particular, the monitoring and optimization of levodopa dosage are critical to mitigate the onset of undesired fluctuations in the patients' physical and emotional conditions such as speech function, motor behavior, and mood stability."1.51Wearable Sweat Band for Noninvasive Levodopa Monitoring. ( Bariya, M; Fan, Z; Hettick, M; Hou, L; Javey, A; Ji, W; Liaw, TS; Lin, Y; Nyein, HYY; Tai, LC; Yuan, Z; Zhao, C; Zhao, J, 2019)
"Noninvasive biomarkers for Parkinson's disease (PD) are currently unavailable."1.43Serum Tyrosine-to-Phenylalanine Ratio is Low in Parkinson's Disease. ( Hirayama, M; Ohno, K; Tsuda, T; Tsunoda, M; Yamamoto, M, 2016)
"In patients with Parkinson's disease, dysfunction of sweating was classified into two types: one type involved the postganglionic fibres and the other involved the preganglionic fibres or the central nervous system."1.29Sweat function in Parkinson's disease. ( Mano, Y; Mayer, RF; Nakamuro, T; Takayanagi, T, 1994)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19906 (40.00)18.7374
1990's2 (13.33)18.2507
2000's0 (0.00)29.6817
2010's3 (20.00)24.3611
2020's4 (26.67)2.80

Authors

AuthorsStudies
Eckhardt, C1
Krismer, F1
Donnemiller, E1
Eschlböck, S1
Fanciulli, A1
Raccagni, C1
Bösch, S1
Mair, K1
Scherfler, C1
Djamshidian, A1
Uprimny, C1
Metzler, B1
Seppi, K1
Poewe, W1
Kiechl, S1
Virgolini, I1
Wenning, GK1
SCHWAB, RS1
CHAPMAN, EM1
ASK-UPMARK, E1
Foster, HD1
Fahn, S1
Prasad, AL1
Delesie, R1
Bora, SS1
Radichevich, I1
Werner, SC1
Curzon, G1
Kantamaneni, BD1
Trigwell, J1
Yu, Z2
Tang, D2
Glasco, DL1
Sheelam, A1
Ho, NHB1
Bell, JG1
Nyein, HYY2
Bariya, M2
Tran, B1
Ahn, CH1
Brown, BJ1
Ji, W2
Davis, N1
Javey, A2
Tai, LC1
Liaw, TS1
Lin, Y1
Hettick, M1
Zhao, C1
Zhao, J1
Hou, L1
Yuan, Z1
Fan, Z1
Tsunoda, M2
Hirayama, M2
Tsuda, T2
Ohno, K2
Yamamoto, M1
Mano, Y1
Nakamuro, T1
Takayanagi, T1
Mayer, RF1
Kumazawa, K1
Sobue, G1
Mitsuma, T1
Sugenoya, J1
Ogawa, T1

Trials

1 trial available for iodine and Parkinson Disease

ArticleYear
Artifactual elevation of PBI from an iodinated dye used to stain medicinal capsules pink.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:9

    Topics: Bipolar Disorder; Blood Proteins; Capsules; Carbonates; Chromatography, Paper; Clinical Trials as To

1969

Other Studies

14 other studies available for iodine and Parkinson Disease

ArticleYear
Cardiac sympathetic innervation in Parkinson's disease versus multiple system atrophy.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2022, Volume: 32, Issue:2

    Topics: 3-Iodobenzylguanidine; Humans; Iodine; Multiple System Atrophy; Parkinson Disease; Prospective Studi

2022
The value of depressing with radioactive iodine the thyroid function of selected patients with Parkinson's disease.
    Transactions of the American Neurological Association, 1954, Volume: 13, Issue:79th Meeti

    Topics: Humans; Iodine; Iodine Radioisotopes; Mental Disorders; Parkinson Disease; Patient Selection; Thyroi

1954
Hyperthyroidism and parkinsonism.
    A.M.A. archives of internal medicine, 1959, Volume: 103, Issue:5

    Topics: Humans; Hyperthyroidism; Iodides; Iodine; Parkinson Disease; Parkinsonian Disorders

1959
Disease family trees: the possible roles of iodine in goitre, cretinism, multiple sclerosis, amyotrophic lateral sclerosis, Alzheimer's and Parkinson's diseases and cancers of the thyroid, nervous system and skin.
    Medical hypotheses, 1987, Volume: 24, Issue:3

    Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Congenital Hypothyroidism; Goiter; Humans; Iodine;

1987
A reliable and simple method for simultaneous determination of DOPA and 3-O-methyldopa in plasma and brain.
    Analytical biochemistry, 1972, Volume: 46, Issue:2

    Topics: Antiparkinson Agents; Brain Chemistry; Carbon Isotopes; Chromatography, Ion Exchange; Cold Temperatu

1972
A method for the determination of dopa and 3-O-methyldopa in the plasma of Parkinsonian patients.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 37

    Topics: Chromatography, Ion Exchange; Dihydroxyphenylalanine; Ferricyanides; Hot Temperature; Humans; Iodine

1972
Artificial Neural Network-Assisted Wearable Flexible Sweat Patch for Drug Management in Parkinson's Patients Based on Vacancy-Engineered Processing of g-C
    Analytical chemistry, 2022, 12-27, Volume: 94, Issue:51

    Topics: Biosensing Techniques; Glucose; Humans; Levodopa; Parkinson Disease; Sweat; Wearable Electronic Devi

2022
Artificial Neural Network-Assisted Wearable Flexible Sweat Patch for Drug Management in Parkinson's Patients Based on Vacancy-Engineered Processing of g-C
    Analytical chemistry, 2022, 12-27, Volume: 94, Issue:51

    Topics: Biosensing Techniques; Glucose; Humans; Levodopa; Parkinson Disease; Sweat; Wearable Electronic Devi

2022
Artificial Neural Network-Assisted Wearable Flexible Sweat Patch for Drug Management in Parkinson's Patients Based on Vacancy-Engineered Processing of g-C
    Analytical chemistry, 2022, 12-27, Volume: 94, Issue:51

    Topics: Biosensing Techniques; Glucose; Humans; Levodopa; Parkinson Disease; Sweat; Wearable Electronic Devi

2022
Artificial Neural Network-Assisted Wearable Flexible Sweat Patch for Drug Management in Parkinson's Patients Based on Vacancy-Engineered Processing of g-C
    Analytical chemistry, 2022, 12-27, Volume: 94, Issue:51

    Topics: Biosensing Techniques; Glucose; Humans; Levodopa; Parkinson Disease; Sweat; Wearable Electronic Devi

2022
Smartphone-based detection of levodopa in human sweat using 3D printed sensors.
    Analytica chimica acta, 2023, Sep-08, Volume: 1273

    Topics: Humans; Levodopa; Parkinson Disease; Printing, Three-Dimensional; Smartphone; Sweat

2023
A wearable patch for continuous analysis of thermoregulatory sweat at rest.
    Nature communications, 2021, 03-23, Volume: 12, Issue:1

    Topics: Biosensing Techniques; Body Temperature Regulation; Human Body; Humans; Hydrogen-Ion Concentration;

2021
Wearable Sweat Band for Noninvasive Levodopa Monitoring.
    Nano letters, 2019, 09-11, Volume: 19, Issue:9

    Topics: Drug Monitoring; Female; Humans; Levodopa; Parkinson Disease; Sweat; Wearable Electronic Devices

2019
Noninvasive monitoring of plasma L-dopa concentrations using sweat samples in Parkinson's disease.
    Clinica chimica acta; international journal of clinical chemistry, 2015, Mar-10, Volume: 442

    Topics: Blood Chemical Analysis; Humans; Levodopa; Parkinson Disease; Sweat

2015
Serum Tyrosine-to-Phenylalanine Ratio is Low in Parkinson's Disease.
    Journal of Parkinson's disease, 2016, 04-02, Volume: 6, Issue:2

    Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Parkinson

2016
Sweat function in Parkinson's disease.
    Journal of neurology, 1994, Volume: 241, Issue:10

    Topics: Aged; Axons; Ceruletide; Galvanic Skin Response; Humans; Parkinson Disease; Skin; Sweat; Sweat Gland

1994
Impairment of calcitonin gene-related peptide-induced potentiation of cholinergic sweat secretion in patients with multiple system atrophy.
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 1997, Volume: 7, Issue:2

    Topics: Autonomic Nervous System Diseases; Calcitonin Gene-Related Peptide; Cerebellar Diseases; Drug Combin

1997