Page last updated: 2024-10-18

iodine and Necrosis

iodine has been researched along with Necrosis in 37 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.

Research Excerpts

ExcerptRelevanceReference
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."7.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
"Thyroid destruction leading to endemic myxoedematous cretinism is highly prevalent in central Africa, where iodine (I) and selenium (SE) deficiencies as well as thiocyanate (SCN) overload are combined."7.72Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa. ( Contempré, B; de Escobar, GM; Denef, JF; Dumont, JE; Many, MC, 2004)
"Necrosis was associated with transient infiltration of inflammatory cells."5.29Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism. ( Contempre, B; Denef, JF; Dumont, JE; Many, MC, 1995)
" Our results demonstrate that iodide in excess, after being oxidized or organified, is directly toxic for iodine-deficient thyroid cells."5.27Direct toxic effect of iodide in excess on iodine-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscin accumulation. ( Colin, I; Denef, JF; Mahmoud, I; Many, MC, 1986)
"We investigated the combined roles of a low-nutrition diet (low levels of protein, iodine, and selenium) and T-2 toxin in bone development and to establish an experimental animal model of Kashin-Beck disease (KBD) that reliably mimics the disease's pathological changes for further study of the pathogenesis and prevention of the disease."3.79An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin. ( Kang, P; Pei, F; Shen, B; Yang, J; Yao, Y; Zhou, Z, 2013)
" Cytotoxicity was assessed with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay, trypan blue testing, and an assay to detect apoptosis and necrosis."3.74Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: in vitro study. ( Grgic, A; Heckmann, MB; Heinrich, MC; Kohlbacher, S; Kuhlmann, MK; Scheer, M; Uder, M, 2007)
"As apoptosis and necrosis are known to exist during experimental goiter development and involution, we studied them in ten Tunisian multinodular endemic goiters, five of them having received a chronic excess of iodine during six months."3.73Chronic iodine overload and apoptosis in cold nodules from endemic multinodular goiters. ( Boubaker, S; El May, A; El May, MV; Ladgham, A; Zekri, S, 2005)
"Thyroid destruction leading to endemic myxoedematous cretinism is highly prevalent in central Africa, where iodine (I) and selenium (SE) deficiencies as well as thiocyanate (SCN) overload are combined."3.72Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa. ( Contempré, B; de Escobar, GM; Denef, JF; Dumont, JE; Many, MC, 2004)
"Certain types of varicose veins can be successfully sclerosed with polyiodinated iodine (PII)."3.69Clinical and histologic evaluation of polyiodinated iodine with and without hypertonic saline/dextrose in the rabbit ear vein model. ( Goldman, MP; Raymond-Martimbeau, P, 1997)
"Necrosis was associated with transient infiltration of inflammatory cells."1.29Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism. ( Contempre, B; Denef, JF; Dumont, JE; Many, MC, 1995)
" Our results demonstrate that iodide in excess, after being oxidized or organified, is directly toxic for iodine-deficient thyroid cells."1.27Direct toxic effect of iodide in excess on iodine-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscin accumulation. ( Colin, I; Denef, JF; Mahmoud, I; Many, MC, 1986)
"Computed tomography demonstrates intracranial neoplasms so clearly that nearly all early work in this field was limited to descriptions of the appearance of various lesions."1.26Some aspects of the computed tomography of the head. ( Kricheff, II; Lin, JP; Pay, N, 1977)

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199020 (54.05)18.7374
1990's6 (16.22)18.2507
2000's5 (13.51)29.6817
2010's4 (10.81)24.3611
2020's2 (5.41)2.80

Authors

AuthorsStudies
Chen, JV1
Ohliger, MA1
Chung, M1
Sugi, MD1
Ye, J1
Nishimura, SL1
Choi, HH1
Li, Q1
Fan, X1
Luo, TY1
Lv, FJ1
Huang, XT1
Reginatto, FP1
Silva, ISB1
Magrin, P1
Caovilla, JJ1
Kang, P1
Yao, Y1
Yang, J1
Shen, B1
Zhou, Z1
Pei, F1
Mehndiratta, A1
Kapal, JM1
Prabu, A1
NIIMI, K1
HOLMQUIST, B1
ALFFRAM, PA1
Contempré, B3
de Escobar, GM1
Denef, JF4
Dumont, JE3
Many, MC4
Wormser, U1
Brodsky, B1
Proscura, E1
Foley, JF1
Jones, T1
Nyska, A1
Landriscina, M1
Fabiano, A1
Altamura, S1
Bagalà, C1
Piscazzi, A1
Cassano, A1
Spadafora, C1
Giorgino, F1
Barone, C1
Cignarelli, M1
El May, MV1
Zekri, S1
Boubaker, S1
Ladgham, A1
El May, A1
Heinrich, MC1
Kuhlmann, MK1
Kohlbacher, S1
Scheer, M1
Grgic, A1
Heckmann, MB1
Uder, M1
Wardle, EN1
Williams, R1
Studer, H1
Ramelli, F1
Yoshikawa, M1
Junck, L1
Enzmann, DR1
DeArmond, SJ1
Okerlund, M1
Amin, Z1
Thurrell, W1
Spencer, GM1
Harries, SA1
Grant, WE1
Bown, SG1
Lees, WR1
Pitsiavas, V1
Smerdely, P1
Li, M1
Boyages, SC1
Goldman, MP1
Raymond-Martimbeau, P1
Strum, JM1
Britton, RS1
Koves, G1
Orrego, H1
Kalant, H1
Phillips, MJ1
Khanna, JM1
Israel, Y1
Shepherd, CJ1
Poupard, CW1
Kricheff, II1
Lin, JP1
Pay, N1
Bicalho, RX1
Rocha, OA1
Heneine, LG1
Magalhães, A1
Heneine, IF1
Mahmoud, I1
Colin, I1
Halfon, D1
Jahier, J1
Feldman, JP1
Kamp, A1
Mavel, A1
Malbranche-Aupècle, MH1
Michiels, R1
Mottot, C1
Belshaw, BE1
Becker, DV1
Brodie, BB2
Krishna, G2
Reid, WD2
Cho, AK1
Taguchi, M1
Thieler, H1
Giertler, R1
Meister, H1
Mitchell, JR1
Christie, B1
Moskowitz, J1
Szemenyei, K1
Kóczé, A1
Jellinek, H1
Papp, M1
Ormai, S1
Csáki, L1
Horváth, E1
Tubiash, HS1
Chanley, PE1
Leifson, E1
Saha, M1
Aich, T1
Das, C1
Mukhopadhyay, M1
Patar, K1

Reviews

1 review available for iodine and Necrosis

ArticleYear
Simple goiter and its variants: euthyroid and hyperthyroid multinodular goiters.
    Endocrine reviews, 1982,Winter, Volume: 3, Issue:1

    Topics: Animals; Blood Vessels; Connective Tissue; Cyclic AMP; DNA; Goiter; Goiter, Nodular; Graves Disease;

1982

Other Studies

36 other studies available for iodine and Necrosis

ArticleYear
Diagnosis of acute mesenteric ischemia assisted by dual-energy CT: a case report.
    Emergency radiology, 2022, Volume: 29, Issue:3

    Topics: Contrast Media; Gastrointestinal Hemorrhage; Humans; Intestine, Small; Iodine; Ischemia; Mesenteric

2022
Differentiating malignant and benign necrotic lung lesions using kVp-switching dual-energy spectral computed tomography.
    BMC medical imaging, 2021, 05-13, Volume: 21, Issue:1

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; C-Reactive Protein; Contrast Media; Diagnosis, Differen

2021
Vegetating lesions from contrast material in a patient with chronic renal failure.
    Clinical and experimental dermatology, 2019, Volume: 44, Issue:8

    Topics: Contrast Media; Diagnosis, Differential; Face; Female; Glucocorticoids; Humans; Hypersensitivity, De

2019
An animal model of Kashin-Beck disease induced by a low-nutrition diet and exposure to T-2 toxin.
    Osteoarthritis and cartilage, 2013, Volume: 21, Issue:8

    Topics: Animal Nutritional Physiological Phenomena; Animals; Cartilage, Articular; Chondrocytes; Dietary Pro

2013
Iodine mapping in brain tumor imaging using dual-energy computed tomography.
    Medical hypotheses, 2011, Volume: 76, Issue:5

    Topics: Brain Neoplasms; Contrast Media; Europe; Humans; Iodine; Necrosis; Positron-Emission Tomography; Pro

2011
[STUDY ON THE UPTAKE OF IN VITRO I-131-LABELLED 1-TRIIODOTHYRONINE BY ERYTHROCYTES IN CHILDREN].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1963, Volume: 67

    Topics: Child; Erythrocytes; Humans; In Vitro Techniques; Infant; Iodine; Iodine Isotopes; Liver Diseases; N

1963
PREDICTION OF AVASCULAR NECROSIS FOLLOWING CERVICAL FRACTURE OF THE FEMUR BASED ON CLEARANCE OF RADIOACTIVE IODINE FROM THE HEAD OF THE FEMUR.
    Acta orthopaedica Scandinavica, 1965, Volume: 36

    Topics: Femoral Neck Fractures; Femur; Femur Head; Humans; Iodine; Iodine Isotopes; Necrosis; Osteonecrosis;

1965
Thiocyanate induces cell necrosis and fibrosis in selenium- and iodine-deficient rat thyroids: a potential experimental model for myxedematous endemic cretinism in central Africa.
    Endocrinology, 2004, Volume: 145, Issue:2

    Topics: Africa, Central; Animals; Antithyroid Agents; Congenital Hypothyroidism; Disease Models, Animal; End

2004
Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
    Archives of toxicology, 2005, Volume: 79, Issue:11

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Antibodies; Dermatitis, Contact; Dermis;

2005
Reverse transcriptase inhibitors down-regulate cell proliferation in vitro and in vivo and restore thyrotropin signaling and iodine uptake in human thyroid anaplastic carcinoma.
    The Journal of clinical endocrinology and metabolism, 2005, Volume: 90, Issue:10

    Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Fluorescent An

2005
Chronic iodine overload and apoptosis in cold nodules from endemic multinodular goiters.
    Archives de l'Institut Pasteur de Tunis, 2005, Volume: 82, Issue:1-4

    Topics: Antigens, CD34; Apoptosis; bcl-2-Associated X Protein; Capillaries; Chronic Disease; Deficiency Dise

2005
Cytotoxicity of iodinated and gadolinium-based contrast agents in renal tubular cells at angiographic concentrations: in vitro study.
    Radiology, 2007, Volume: 242, Issue:2

    Topics: Angiography; Animals; Apoptosis; Cell Death; Coloring Agents; Contrast Media; Gadolinium; Gadolinium

2007
Polymorph leucocyte function in uraemia and jaundice.
    Acta haematologica, 1980, Volume: 64, Issue:3

    Topics: Blood Glucose; Cholestasis; Esterases; Humans; Iodine; Jaundice; Leucine; Liver; Liver Cirrhosis, Al

1980
Experimental study for the tissue reaction caused by the implanted autologous autolytic tissue treated with some anti-infectives.
    Journal of Osaka Dental University, 1980, Volume: 14

    Topics: Animals; Anti-Infective Agents, Local; Dental Pulp Necrosis; Fixatives; Formaldehyde; Iodine; Male;

1980
Prolonged brain retention of contrast agent in neonatal herpes simplex encephalitis.
    Radiology, 1981, Volume: 140, Issue:1

    Topics: Brain; Diatrizoate; Encephalitis; Female; Herpes Simplex; Humans; Infant, Newborn; Infant, Newborn,

1981
Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism.
    European journal of endocrinology, 1995, Volume: 133, Issue:1

    Topics: Animals; Cell Division; Epithelium; Female; Fibrosis; Free Radicals; Goiter; Hydrogen Peroxide; Hype

1995
Computed tomography-pathologic assessment of laser-induced necrosis in rat liver.
    Investigative radiology, 1993, Volume: 28, Issue:12

    Topics: Animals; Contrast Media; Iodine; Laser Coagulation; Linear Models; Liver; Male; Necrosis; Rats; Rats

1993
Selenium deficiency aggravates the necrotizing effects of a high iodide dose in iodine deficient rats.
    Endocrinology, 1993, Volume: 132, Issue:4

    Topics: Animals; Dose-Response Relationship, Drug; Glutathione Peroxidase; Iodides; Iodine; Necrosis; Rats;

1993
Amiodarone induces a different pattern of ultrastructural change in the thyroid to iodine excess alone in both the BB/W rat and the Wistar rat.
    European journal of endocrinology, 1997, Volume: 137, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Cell Nucleus; Endoplasmic Reticulum; Inclusi

1997
Clinical and histologic evaluation of polyiodinated iodine with and without hypertonic saline/dextrose in the rabbit ear vein model.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1997, Volume: 23, Issue:8

    Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Drug Combinations; Ear, External; Endothelium, Vas

1997
Effect of iodide-deficiency on rat mammary gland.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1979, May-31, Volume: 30, Issue:2

    Topics: Animals; Atrophy; Cell Nucleolus; Estradiol; Female; Iodine; Mammary Glands, Animal; Microscopy, Ele

1979
Suppression by antithyroid drugs of experimental hepatic necrosis after ethanol treatment. Effect on thyroid gland or on peripheral deiodination?
    Toxicology and applied pharmacology, 1979, Volume: 51, Issue:1

    Topics: Animals; Antithyroid Agents; Chemical and Drug Induced Liver Injury; Ethanol; Hypoxia; Iodine; Male;

1979
Veterinary aspects of salmonid fish farming: husbandry diseases.
    The Veterinary record, 1975, Jul-19, Volume: 97, Issue:3

    Topics: Aflatoxins; Animal Feed; Animals; Apicomplexa; Bacterial Infections; Fatty Liver; Female; Fish Disea

1975
Some aspects of the computed tomography of the head.
    National Cancer Institute monograph, 1977, Volume: 46

    Topics: Brain Edema; Brain Neoplasms; Contrast Media; Iodine; Necrosis; Radiation Injuries; Tomography, X-Ra

1977
The effect of stepwise iodination on biological properties of Bothrops jararaca venom.
    Toxicon : official journal of the International Society on Toxinology, 1990, Volume: 28, Issue:2

    Topics: Animals; Captopril; Crotalid Venoms; Epinephrine; Female; Hemorrhage; Iodine; Lethal Dose 50; Male;

1990
Direct toxic effect of iodide in excess on iodine-deficient thyroid glands: epithelial necrosis and inflammation associated with lipofuscin accumulation.
    Experimental and molecular pathology, 1986, Volume: 44, Issue:3

    Topics: Animals; Epithelium; Humans; Iodides; Iodine; Lipofuscin; Male; Mice; Mice, Inbred ICR; Microscopy,

1986
[The "white" cervix: a new anatomo-clinical entity?].
    Revue francaise de gynecologie et d'obstetrique, 1985, Volume: 80, Issue:2

    Topics: Acetates; Epithelium; Female; Humans; Iodine; Necrosis; Uterine Cervical Diseases; Uterine Cerviciti

1985
Necrosis of follicular cells and discharge of thyroidal iodine induced by administering iodide to iodine-deficient dogs.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:3

    Topics: Animals; Dogs; Epithelium; Female; Iodides; Iodine; Iodine Radioisotopes; Kinetics; Necrosis; Thyroi

1973
Drug metabolism in man: past, present, and future.
    Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179

    Topics: Aerobiosis; Alkylating Agents; Allyl Compounds; Animals; Autoradiography; Bromine; Carbon Isotopes;

1971
[Clinico-pathological study of pulpotomy on the middle portion of the root canal of vital human deciduous teeth].
    Shika gakuho. Dental science reports, 1972, Volume: 72, Issue:3

    Topics: Calcium Hydroxide; Child; Child, Preschool; Cicatrix; Cold Temperature; Dental Caries; Dental Pulp;

1972
[Acute toxic kidney failure caused by an overdose of Vistarin].
    Zeitschrift fur arztliche Fortbildung, 1973, Jul-01, Volume: 67, Issue:13

    Topics: Acute Kidney Injury; Adult; Epithelial Cells; Epithelium; Female; Humans; Iodides; Iodine; Male; Mid

1973
Bromobenzene-induced hepatic necrosis: species differences and protection by SKF 525-A.
    Research communications in chemical pathology and pharmacology, 1971, Volume: 2, Issue:6

    Topics: Age Factors; Animals; Animals, Newborn; Anura; Bufo marinus; Chemical and Drug Induced Liver Injury;

1971
Experimental injury of muscular-type blood vessels by chemical agents.
    Acta morphologica Academiae Scientiarum Hungaricae, 1968, Volume: 16, Issue:2

    Topics: Animals; Arteries; Burns, Chemical; Female; Femoral Artery; Hydrochloric Acid; Iodine; Male; Muscle,

1968
The role of lymph and blood circulation in pancreatic self-digestion and the development of extrapancreatic necroses.
    Acta medica Academiae Scientiarum Hungaricae, 1968, Volume: 25, Issue:3

    Topics: Amylases; Animals; Autolysis; Blood Proteins; Chromium Isotopes; Dogs; Female; Iodine; Lipase; Liver

1968
Bacillary necrosis, a disease of larval and juvenile bivalve mollusks. I. Etiology and epizootiology.
    Journal of bacteriology, 1965, Volume: 90, Issue:4

    Topics: Aeromonas; Anti-Bacterial Agents; Bacteria; Iodine; Mollusca; Necrosis; Povidone; Sulfamethazine; Vi

1965
Medical image. Septicaemia with acute renal failure.
    The New Zealand medical journal, 2012, Apr-20, Volume: 125, Issue:1353

    Topics: Acute Kidney Injury; Adult; Fatal Outcome; Humans; Kidney Tubules; Male; Necrosis; Sepsis; Sweat; Ur

2012