iodine and Leg Ulcer
iodine has been researched along with Leg Ulcer in 14 studies
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical data suggests that iodine released into the wound environment by Iodosorb may enhance the healing of chronic leg ulcers by a mechanism additional to its anti-bacterial activity." | 3.69 | Iodine released from the wound dressing Iodosorb modulates the secretion of cytokines by human macrophages responding to bacterial lipopolysaccharide. ( Harding, KG; Moore, K; Thomas, A, 1997) |
Research
Studies (14)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (85.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Thomas, C | 1 |
| THORNE, N | 1 |
| FOX, D | 1 |
| MCKNIGHT, AG | 1 |
| BULL, GM | 1 |
| FRASER, R | 1 |
| Skog, E | 1 |
| Arnesjö, B | 1 |
| Troëng, T | 1 |
| Gjöres, JE | 1 |
| Bergljung, L | 1 |
| Gundersen, J | 1 |
| Hallböök, T | 1 |
| Hessman, Y | 1 |
| Hillström, L | 2 |
| Månsson, T | 1 |
| Eilard, U | 1 |
| Eklöff, B | 1 |
| Plate, G | 1 |
| Norgren, L | 1 |
| Moore, K | 1 |
| Thomas, A | 1 |
| Harding, KG | 1 |
| Ruzicka, T | 1 |
| Goerz, G | 1 |
| Altman, MA | 1 |
| Richter, IH | 1 |
| Kaplan, LH | 1 |
| Tarvainen, K | 1 |
| Floyer, C | 1 |
| Wilkinson, JD | 1 |
| Harcup, JW | 1 |
| Saul, PA | 1 |
| Antrobus, M | 1 |
| Shuttleworth, GJ | 1 |
| Mayho, GV | 1 |
Trials
4 trials available for iodine and Leg Ulcer
| Article | Year |
|---|---|
A randomized trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers.
Topics: Administration, Topical; Aged; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparation | 1983 |
Cadexomer iodine (Iodosorb) compared with dextranomer (Debrisan) in the treatment of chronic leg ulcers.
Topics: Adult; Aged; Aged, 80 and over; Bacteria; Chronic Disease; Dextrans; Drug Evaluation; Drug Tolerance | 1988 |
Iodosorb compared to standard treatment in chronic venous leg ulcers--a multicenter study.
Topics: Aged; Chronic Disease; Female; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Male; Microsp | 1988 |
A study of the effect of cadexomer iodine in the treatment of venous leg ulcers.
Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Iodine; Iodine Compoun | 1986 |
Other Studies
10 other studies available for iodine and Leg Ulcer
| Article | Year |
|---|---|
What causes a leg ulcer to become chronic?
Topics: Aged, 80 and over; Chronic Disease; Cnidarian Venoms; Compression Bandages; Humans; Iodine; Leg Ulce | 2018 |
A TRIAL OF PROVIDONE-IODINE OINTMENT IN THE TREATMENT OF LEG ULCERS.
Topics: Anti-Infective Agents, Local; Drug Therapy; Halogens; Humans; Hydrocarbons, Halogenated; Iodine; Leg | 1965 |
A CLINICAL TRIAL OF POVIDONE-IODINE IN THE TREATMENT OF CHRONIC LEG ULCERS.
Topics: Drug Therapy; Humans; Iodine; Leg Ulcer; Ointments; Povidone; Povidone-Iodine; Skin Ulcer | 1965 |
Myxoedema from resorcinol ointment applied to leg ulcers.
Topics: Humans; Iodine; Iodine Radioisotopes; Leg Ulcer; Myxedema; Resorcinols; Thyroid Gland; Varicose Vein | 1950 |
Iodine released from the wound dressing Iodosorb modulates the secretion of cytokines by human macrophages responding to bacterial lipopolysaccharide.
Topics: Animals; Bandages; Cell Line; Cytokines; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Lip | 1997 |
[Necrosis caused by disinfectants].
Topics: Aged; Child; Dermatitis, Contact; Disinfectants; Female; Humans; Iatrogenic Disease; Iodine; Leg Ulc | 1979 |
Use of an aqueous triple iodine solution in the treatment of chronic leg ulcers and gangrene.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diabetes Complications; Female; Gangrene; Humans; I | 1976 |
Treatment of venous leg ulcers with cadexomer iodine with particular reference to iodine sensitivity.
Topics: Drug Eruptions; Drug Evaluation; Female; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Mal | 1988 |
Leg ulcers--setting standards of care.
Topics: Aged; Bandages; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer | 1987 |
Controlled trial of Iodosorb in chronic venous ulcers.
Topics: Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Polyethylene Glycols | 1985 |