Page last updated: 2024-10-18

iodine and Leg Ulcer

iodine has been researched along with Leg Ulcer in 14 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.

Research Excerpts

ExcerptRelevanceReference
"Clinical data suggests that iodine released into the wound environment by Iodosorb may enhance the healing of chronic leg ulcers by a mechanism additional to its anti-bacterial activity."3.69Iodine released from the wound dressing Iodosorb modulates the secretion of cytokines by human macrophages responding to bacterial lipopolysaccharide. ( Harding, KG; Moore, K; Thomas, A, 1997)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199012 (85.71)18.7374
1990's1 (7.14)18.2507
2000's0 (0.00)29.6817
2010's1 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Thomas, C1
THORNE, N1
FOX, D1
MCKNIGHT, AG1
BULL, GM1
FRASER, R1
Skog, E1
Arnesjö, B1
Troëng, T1
Gjöres, JE1
Bergljung, L1
Gundersen, J1
Hallböök, T1
Hessman, Y1
Hillström, L2
Månsson, T1
Eilard, U1
Eklöff, B1
Plate, G1
Norgren, L1
Moore, K1
Thomas, A1
Harding, KG1
Ruzicka, T1
Goerz, G1
Altman, MA1
Richter, IH1
Kaplan, LH1
Tarvainen, K1
Floyer, C1
Wilkinson, JD1
Harcup, JW1
Saul, PA1
Antrobus, M1
Shuttleworth, GJ1
Mayho, GV1

Trials

4 trials available for iodine and Leg Ulcer

ArticleYear
A randomized trial comparing cadexomer iodine and standard treatment in the out-patient management of chronic venous ulcers.
    The British journal of dermatology, 1983, Volume: 109, Issue:1

    Topics: Administration, Topical; Aged; Chronic Disease; Clinical Trials as Topic; Delayed-Action Preparation

1983
Cadexomer iodine (Iodosorb) compared with dextranomer (Debrisan) in the treatment of chronic leg ulcers.
    Acta chirurgica Scandinavica. Supplementum, 1988, Volume: 544

    Topics: Adult; Aged; Aged, 80 and over; Bacteria; Chronic Disease; Dextrans; Drug Evaluation; Drug Tolerance

1988
Iodosorb compared to standard treatment in chronic venous leg ulcers--a multicenter study.
    Acta chirurgica Scandinavica. Supplementum, 1988, Volume: 544

    Topics: Aged; Chronic Disease; Female; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Male; Microsp

1988
A study of the effect of cadexomer iodine in the treatment of venous leg ulcers.
    The British journal of clinical practice, 1986, Volume: 40, Issue:9

    Topics: Adult; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Iodine; Iodine Compoun

1986

Other Studies

10 other studies available for iodine and Leg Ulcer

ArticleYear
What causes a leg ulcer to become chronic?
    British journal of community nursing, 2018, Sep-01, Volume: 23, Issue:Sup9

    Topics: Aged, 80 and over; Chronic Disease; Cnidarian Venoms; Compression Bandages; Humans; Iodine; Leg Ulce

2018
A TRIAL OF PROVIDONE-IODINE OINTMENT IN THE TREATMENT OF LEG ULCERS.
    The Practitioner, 1965, Volume: 194

    Topics: Anti-Infective Agents, Local; Drug Therapy; Halogens; Humans; Hydrocarbons, Halogenated; Iodine; Leg

1965
A CLINICAL TRIAL OF POVIDONE-IODINE IN THE TREATMENT OF CHRONIC LEG ULCERS.
    The Practitioner, 1965, Volume: 195

    Topics: Drug Therapy; Humans; Iodine; Leg Ulcer; Ointments; Povidone; Povidone-Iodine; Skin Ulcer

1965
Myxoedema from resorcinol ointment applied to leg ulcers.
    Lancet (London, England), 1950, May-06, Volume: 1, Issue:6610

    Topics: Humans; Iodine; Iodine Radioisotopes; Leg Ulcer; Myxedema; Resorcinols; Thyroid Gland; Varicose Vein

1950
Iodine released from the wound dressing Iodosorb modulates the secretion of cytokines by human macrophages responding to bacterial lipopolysaccharide.
    The international journal of biochemistry & cell biology, 1997, Volume: 29, Issue:1

    Topics: Animals; Bandages; Cell Line; Cytokines; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Lip

1997
[Necrosis caused by disinfectants].
    Dermatosen in Beruf und Umwelt. Occupation and environment, 1979, Volume: 27, Issue:5

    Topics: Aged; Child; Dermatitis, Contact; Disinfectants; Female; Humans; Iatrogenic Disease; Iodine; Leg Ulc

1979
Use of an aqueous triple iodine solution in the treatment of chronic leg ulcers and gangrene.
    Angiology, 1976, Volume: 27, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diabetes Complications; Female; Gangrene; Humans; I

1976
Treatment of venous leg ulcers with cadexomer iodine with particular reference to iodine sensitivity.
    Acta chirurgica Scandinavica. Supplementum, 1988, Volume: 544

    Topics: Drug Eruptions; Drug Evaluation; Female; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Mal

1988
Leg ulcers--setting standards of care.
    Geriatric nursing and home care, 1987, Volume: 7, Issue:8

    Topics: Aged; Bandages; Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer

1987
Controlled trial of Iodosorb in chronic venous ulcers.
    British medical journal (Clinical research ed.), 1985, Aug-31, Volume: 291, Issue:6495

    Topics: Humans; Iodine; Iodine Compounds; Iodophors; Leg Ulcer; Polyethylene Glycols

1985