Page last updated: 2024-10-18

iodine and Intellectual Disability

iodine has been researched along with Intellectual Disability in 71 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Intellectual Disability: Subnormal intellectual functioning which originates during the developmental period. This has multiple potential etiologies, including genetic defects and perinatal insults. Intelligence quotient (IQ) scores are commonly used to determine whether an individual has an intellectual disability. IQ scores between 70 and 79 are in the borderline range. Scores below 67 are in the disabled range. (from Joynt, Clinical Neurology, 1992, Ch55, p28)

Research Excerpts

ExcerptRelevanceReference
"Iodine intake must be boosted during pregnancy to meet the demands for increased production and placental transfer of thyroid hormone essential for optimal foetal development."9.01Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions. ( Eastman, CJ; Li, M; Ma, G, 2019)
" When the intake is restricted, physiological adaptation is progressively replaced by pathological alterations, in parallel with the degree of iodine deprivation, leading to excessive glandular stimulation, hypothyroxinemia, and goiter formation."8.82Feto-maternal repercussions of iodine deficiency during pregnancy. An update. ( Glinoer, D, 2003)
"Neurological examinations were made of 67 children and adults with congenital iodine-deficiency disorder (endemic cretinism) in four rural villages in highland Ecuador."7.67Neurological signs in congenital iodine-deficiency disorder (endemic cretinism). ( DeLong, GR; Fierro-Benitez, R; Stanbury, JB, 1985)
"Iodine is an integral part of the thyroid hormones, thyroxine (T(4)) and tri-iodothyronine (T(3)), necessary for normal growth and development."6.47Iodine deficiency in pregnancy: the effect on neurodevelopment in the child. ( Skeaff, SA, 2011)
"Iodine is a trace element essential for synthesis of the thyroid hormones, triiodothyronine and thyroxine."6.44Iodine and thyroid hormones during pregnancy and postpartum. ( Pérez-López, FR, 2007)
"Iodine intake must be boosted during pregnancy to meet the demands for increased production and placental transfer of thyroid hormone essential for optimal foetal development."5.01Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions. ( Eastman, CJ; Li, M; Ma, G, 2019)
"Iodine, as a component of the thyroid hormones, is crucial for brain development and is therefore especially important during pregnancy when the brain is developing most rapidly."4.91A review of the iodine status of UK pregnant women and its implications for the offspring. ( Bath, SC; Rayman, MP, 2015)
"Severe iodine deficiency during pregnancy seriously influences fetal brain development and in the worst case induces cretinism."4.86[Iodine deficiency in infancy - a risk for cognitive development]. ( Gärtner, R; Johner, SA; Kriener, E; Remer, T; Thamm, M, 2010)
" When the intake is restricted, physiological adaptation is progressively replaced by pathological alterations, in parallel with the degree of iodine deprivation, leading to excessive glandular stimulation, hypothyroxinemia, and goiter formation."4.82Feto-maternal repercussions of iodine deficiency during pregnancy. An update. ( Glinoer, D, 2003)
" Iodine deficiency is particularly important in pregnancy as the fetus relies on maternal thyroxine (T4) exclusively during the first 14 weeks and also throughout gestation."3.81The importance of iodine in public health. ( Lazarus, JH, 2015)
"Iodine concentrations of enteral nutrition (EN) formulae available in Japan are very low and long-term total EN (TEN) might result in hypothyroidism due to iodine deficiency (HID)."3.78Investigation of iodine deficient state and iodine supplementation in patients with severe motor and intellectual disabilities on long-term total enteral nutrition. ( Honjo, T; Hotsubo, T; Kamasaki, H; Takeuchi, T; Tsugawa, S; Tsutsumi, H; Yoto, Y, 2012)
"Intelligence in children without iodine supplement during their fetal and infant periods, and in those born three to four years after the implementation of stable supply of iodized salt in the areas with endemic cretinism and goiter was tested with Standord-Binet method."3.69[Effects of iodine nutritional status of fetuses, infants and young children on their intelligence development in the areas with iodine-deficiency disorders]. ( Chen, ZH; Deng, LQ; Fu, LX, 1994)
"Endemic cretinism is still present in an endemic goiter area of the central Apennines (Montefeltro) (goiter prevalence 55%; mean urinary iodine level 39 micrograms/g creatinine)."3.68Clinical picture of endemic cretinism in central Apennines (Montefeltro). ( Andreani, M; Antonelli, A; Baschieri, L; Bertoni, F; Donati, L; Filippi, T; Gasperini, L; Moscogiuri, D; Neri, S; Venturi, S, 1992)
"Neurological examinations were made of 67 children and adults with congenital iodine-deficiency disorder (endemic cretinism) in four rural villages in highland Ecuador."3.67Neurological signs in congenital iodine-deficiency disorder (endemic cretinism). ( DeLong, GR; Fierro-Benitez, R; Stanbury, JB, 1985)
"Severe iodine deficiency may lead to endemic cretinism, which is characterized by a number of abnormalities, such as mental retardation, neurological abnormalities and hearing disorders."3.66Effects of iodine deficiency on mental and psychomotor abilities. ( Bleichrodt, N; Drenth, PJ; Querido, A, 1980)
" Serum free T(4) and TSH should be checked at intervals frequent enough to ensure timely adjustment of l-T(4) dosing and to keep serum free T(4) and TSH levels in target ranges."2.47Approach to the diagnosis and treatment of neonatal hypothyroidism. ( LaFranchi, SH, 2011)
"Iodine is an integral part of the thyroid hormones, thyroxine (T(4)) and tri-iodothyronine (T(3)), necessary for normal growth and development."2.47Iodine deficiency in pregnancy: the effect on neurodevelopment in the child. ( Skeaff, SA, 2011)
"Iodine is a trace element essential for synthesis of the thyroid hormones, triiodothyronine and thyroxine."2.44Iodine and thyroid hormones during pregnancy and postpartum. ( Pérez-López, FR, 2007)
"Severe mental retardation of the child can occur due to compromised iodine intake or thyroid disease."2.43Thyroid hormones and fetal brain development. ( Franklyn, JA; Kilby, MD; Pemberton, HN, 2005)
" High quality controlled studies investigating relevant long term outcome measures are needed to address questions of dosage and best means of iodine supplementation in different population groups and settings."2.41Iodised salt for preventing iodine deficiency disorders. ( Clar, C; Li, P; Liu, GJ; Wu, T, 2002)
"Iodine nutrition plays an important and positive role in brain development."2.41[A preliminary meta-analysis of 36 studies on impairment of intelligence development induced by iodine deficiency]. ( Chen, Z; Qian, M; Wang, D, 2000)
"The main cause of endemic goiter and cretinism is an insufficient dietary supply of iodine."2.39The disorders induced by iodine deficiency. ( Delange, F, 1994)
" iodisation of salt at the current level of fortification (15-30 ppm iodine) keeps intakes well within a safe daily range for all populations, irrespective of their iodine status."2.39Human requirements of iodine & safe use of iodised salt. ( Ranganathan, S; Reddy, V, 1995)
"2."2.38[Disorders due to iodine deficiency]. ( Delange, F, 1990)
"Individuals with mild or borderline intellectual disability (MBID) are at risk of substance use (SU)."1.46Substance use in individuals with mild to borderline intellectual disability: A comparison between self-report, collateral-report and biomarker analysis. ( Buitelaar, JK; de Jong, CA; Didden, R; Kiewik, M; Korzilius, HP; Koster, RA; Uges, DR; van der Palen, J; van Dijk, M; VanDerNagel, JE, 2017)
"The frequency of SH in children with neurological disorders was of 7."1.32[Frequency of subclinical hypothyroidism among healthy children and those with neurological conditions in the state of Mérida, Venezuela]. ( Arata-Bellabarba, G; Arias-Ferreira, A; Bianchi, G; Jiménez-López, V; Mamán-Alvarado, D; Paoli-Valeri, M, 2003)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199030 (42.25)18.7374
1990's10 (14.08)18.2507
2000's18 (25.35)29.6817
2010's13 (18.31)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eastman, CJ1
Ma, G1
Li, M1
Li, J2
Zhang, F2
Wang, Y2
Qin, W1
Xing, Q1
Qian, X1
Guo, T1
Gao, X1
He, L4
Gao, J3
Lazarus, JH1
Bath, SC1
Rayman, MP1
Trumpff, C1
De Schepper, J1
Vanderfaeillie, J1
Vercruysse, N1
Van Oyen, H1
Moreno-Reyes, R1
Tafforeau, J1
Vanderpas, J1
Vandevijvere, S1
Kanık Yüksek, S1
Aycan, Z1
Öner, Ö1
Cai, Z1
Zhao, Q1
Xing, Y1
Xu, J1
Liu, Y1
Shao, L1
Che, R1
Wei, Z1
Remer, T1
Johner, SA1
Gärtner, R1
Thamm, M1
Kriener, E1
Mansourian, AR1
LaFranchi, SH1
Skeaff, SA1
Takeuchi, T1
Kamasaki, H1
Yoto, Y1
Honjo, T1
Tsugawa, S1
Hotsubo, T1
Tsutsumi, H1
Kiss, L1
Wu, T1
Liu, GJ1
Li, P1
Clar, C1
Glinoer, D2
HENI, F1
SIEBNER, H1
PARKER, RH1
BEIERWALTES, WH1
Paoli-Valeri, M1
Mamán-Alvarado, D1
Jiménez-López, V1
Arias-Ferreira, A1
Bianchi, G1
Arata-Bellabarba, G1
Guo, TW2
Zhang, FC2
Yang, MS1
Gao, XC2
Bian, L2
Duan, SW1
Zheng, ZJ2
Gao, JJ1
Wang, H1
Li, RL2
Feng, GY2
St Clair, D1
Kapil, U1
Singh, P1
Dwivedi, SN1
Pathak, P1
Semenova, NB1
Manchuk, VT1
Pemberton, HN1
Franklyn, JA1
Kilby, MD1
Yang, M1
Ji, Q1
Ma, J1
Büyükgebiz, A1
Pérez-López, FR1
Muela Martínez, JA1
García León, A1
Torres Barahona, R1
Santiago Fernández, P1
Sóriguer Escofet, F1
Michaud, P1
Telléz, R1
López, JM1
Aguirre, R1
Telléz, A1
Valdivieso, S1
Bleichrodt, N1
Drenth, PJ1
Querido, A3
Hetzel, BS1
Fu, LX1
Chen, ZH1
Deng, LQ1
Delange, F5
Bürgi, H1
Ranganathan, S1
Reddy, V1
Grantham-McGregor, SM1
Fernald, LC1
Gao, B1
Yin, G1
Owada, M1
de Benoist, B1
Pretell, E1
Dunn, JT1
Qian, M1
Wang, D1
Chen, Z1
Marek, A1
Rogowski, A1
Perez-Cuvit, E1
Crigler, JF1
Stanbury, JB5
Hornabrook, RW1
Donati, L1
Antonelli, A1
Bertoni, F1
Moscogiuri, D1
Andreani, M1
Venturi, S1
Filippi, T1
Gasperini, L1
Neri, S1
Baschieri, L1
Fierro-Benitez, R4
Cazar, R1
Rodriguez, P1
Garces, F1
Fierro-Renoy, F1
Estrella, E1
Stein, Z1
Susser, M1
DeLong, GR1
Rocmans, P1
Buhler, UK1
Ochi, Y1
Man, EB1
Jones, WS1
Mosier, HD1
Rajalakshmi, R1
Ramakrishnan, CV1
Trowbridge, FL1
Pharoah, PO1
Yoshimura, M1
Miyazaki, T1
Shiomi, K1
Hachiya, T1
Koshichi, Y1
Marescotti, V1
Saba, P1
Pariante, F1
Galeone, F1
Ermans, A1
Remvig, J1
Kremenová, J1
Reisenauer, R1
Penafiel, W1
De Groot, LJ1
Ramirez, I1
VanDerNagel, JE1
Kiewik, M1
van Dijk, M1
Didden, R1
Korzilius, HP1
van der Palen, J1
Buitelaar, JK1
Uges, DR1
Koster, RA1
de Jong, CA1
Geetha, H1
Jayakeerthy, CM1
Vassella, F2
Emrich, HM1
Kraus-Ruppert, R1
Aufdermaur, F1
Tönz, O2
Kohlschütter, A1
Chappuis, D1
Meier, C1
Herschkowitz, N1
Grassi, A1
Matsumoto, K1
Gerritsen, T1
Kaveggia, E1
Waisman, HA1

Reviews

26 reviews available for iodine and Intellectual Disability

ArticleYear
Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions.
    Nutrients, 2019, Oct-05, Volume: 11, Issue:10

    Topics: Age Factors; Child Development; Child, Preschool; Deficiency Diseases; Diet; Dietary Supplements; Fe

2019
A review of the iodine status of UK pregnant women and its implications for the offspring.
    Environmental geochemistry and health, 2015, Volume: 37, Issue:4

    Topics: Adult; Child; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Iodine; Mate

2015
[Iodine deficiency in infancy - a risk for cognitive development].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:31-32

    Topics: Breast Feeding; Child; Congenital Hypothyroidism; Female; Food, Organic; Germany; Goiter, Endemic; H

2010
A review on the metabolic disorders of iodine deficiency.
    Pakistan journal of biological sciences : PJBS, 2011, Apr-01, Volume: 14, Issue:7

    Topics: Adult; Brain; Brain Diseases, Metabolic; Female; Humans; Hypothyroidism; Infant, Newborn; Intellectu

2011
Approach to the diagnosis and treatment of neonatal hypothyroidism.
    The Journal of clinical endocrinology and metabolism, 2011, Volume: 96, Issue:10

    Topics: Congenital Hypothyroidism; Female; Humans; Immunoglobulins, Thyroid-Stimulating; Infant, Newborn; In

2011
Iodine deficiency in pregnancy: the effect on neurodevelopment in the child.
    Nutrients, 2011, Volume: 3, Issue:2

    Topics: Brain; Child; Female; Fetal Development; Humans; Hypothyroidism; Intellectual Disability; Iodine; Pr

2011
Iodised salt for preventing iodine deficiency disorders.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Cross-Sectional Studies; Dietary Supplements; Humans; Intellectual Disability; Iodine; Prospective S

2002
Feto-maternal repercussions of iodine deficiency during pregnancy. An update.
    Annales d'endocrinologie, 2003, Volume: 64, Issue:1

    Topics: Diet; Female; Goiter; Humans; Intellectual Disability; Iodine; Nervous System Diseases; Pregnancy; P

2003
[An effect of iodine deficiency on neuromental development: a modern view on the problem].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Volume: 105, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Congenital Hypothyroidism; Female; Fetal Development; Ge

2005
Thyroid hormones and fetal brain development.
    Minerva ginecologica, 2005, Volume: 57, Issue:4

    Topics: Animals; Brain; Disease Models, Animal; Female; Fetal Development; Fetal Growth Retardation; Fetus;

2005
Newborn screening for congenital hypothyroidism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2006, Volume: 19, Issue:11

    Topics: Congenital Hypothyroidism; Humans; Infant, Newborn; Intellectual Disability; Iodine; Neonatal Screen

2006
Iodine and thyroid hormones during pregnancy and postpartum.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2007, Volume: 23, Issue:7

    Topics: Brain; Dietary Supplements; Female; Fetal Development; Humans; Intellectual Disability; Iodine; Nutr

2007
The disorders induced by iodine deficiency.
    Thyroid : official journal of the American Thyroid Association, 1994,Spring, Volume: 4, Issue:1

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Congenital Hypothyroidism; Democratic Republic of

1994
Human requirements of iodine & safe use of iodised salt.
    The Indian journal of medical research, 1995, Volume: 102

    Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; India; Infant; Infant, Newborn; Intellec

1995
Nutritional deficiencies and subsequent effects on mental and behavioral development in children.
    The Southeast Asian journal of tropical medicine and public health, 1997, Volume: 28 Suppl 2

    Topics: Achievement; Adolescent; Anemia, Iron-Deficiency; Child; Child Development; Child Nutrition Disorder

1997
[Fetal iodine deficiency disorder].
    Ryoikibetsu shokogun shirizu, 2000, Issue:30 Pt 5

    Topics: Congenital Hypothyroidism; Diagnosis, Differential; Endemic Diseases; Female; Fetal Diseases; Humans

2000
Iodine deficiency as a cause of brain damage.
    Postgraduate medical journal, 2001, Volume: 77, Issue:906

    Topics: Brain Damage, Chronic; Female; Humans; Infant, Newborn; Intellectual Disability; Iodine; Pregnancy;

2001
Iodine deficiency in the world: where do we stand at the turn of the century?
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Female; Humans; Hyperthyroidism; Intellectual Disability; Iodine; Maternal-Fetal Exchange; Pregnancy

2001
Pregnancy and iodine.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Female; Goiter; Humans; Intellectual Disability; Iodine; Maternal-Fetal Exchange; Nervous System Dis

2001
[A preliminary meta-analysis of 36 studies on impairment of intelligence development induced by iodine deficiency].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2000, Volume: 34, Issue:2

    Topics: Adolescent; Child; Child, Preschool; Humans; Intellectual Disability; Intelligence; Iodine

2000
Endemic Cretinism.
    Contemporary neurology series, 1975, Volume: 12

    Topics: Adolescent; Adult; Aged; Brain; Child; Child, Preschool; Congenital Hypothyroidism; Congo; Deafness;

1975
[Disorders due to iodine deficiency].
    Acta clinica Belgica, 1990, Volume: 45, Issue:6

    Topics: Adult; Child; Child, Preschool; Congenital Hypothyroidism; Developing Countries; Female; Goiter, End

1990
Effects of early nutrition on neurological and mental competence in human beings.
    Psychological medicine, 1985, Volume: 15, Issue:4

    Topics: Brain; Child, Preschool; Cognition; Congenital Hypothyroidism; Female; Fertilization; Fetus; Humans;

1985
Nutrition and brain function.
    World review of nutrition and dietetics, 1972, Volume: 15

    Topics: Age Factors; Aminobutyrates; Animals; Body Height; Brain; Brain Chemistry; Child; Child, Preschool;

1972
Biochemistry of mental disorders. Report of a WHO Scientific Group.
    World Health Organization technical report series, 1969, Volume: 427

    Topics: Adult; Affective Symptoms; Avitaminosis; Behavior; Brain; Brain Chemistry; Child; Chromosome Aberrat

1969
[Gastric, intestinal and pancreatic diseases and pulmonary findings (including esophageal diseases)].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:9

    Topics: Adult; Celiac Disease; Chlorides; Cystic Fibrosis; Esophageal Neoplasms; Female; Gastrointestinal Di

1971

Other Studies

45 other studies available for iodine and Intellectual Disability

ArticleYear
Association between ε2/3/4, promoter polymorphism (-491A/T, -427T/C, and -219T/G) at the apolipoprotein E gene, and mental retardation in children from an iodine deficiency area, China.
    BioMed research international, 2014, Volume: 2014

    Topics: Adolescent; Apolipoproteins E; Base Sequence; Child; China; Comorbidity; Female; Genetic Association

2014
The importance of iodine in public health.
    Environmental geochemistry and health, 2015, Volume: 37, Issue:4

    Topics: Child; Female; Humans; Hyperthyroidism; Hyperthyroxinemia; Hypothyroidism; Intellectual Disability;

2015
Thyroid-Stimulating Hormone (TSH) Concentration at Birth in Belgian Neonates and Cognitive Development at Preschool Age.
    Nutrients, 2015, Nov-02, Volume: 7, Issue:11

    Topics: Belgium; Child; Child Development; Child, Preschool; Cognition; Cohort Studies; Confounding Factors,

2015
Evaluation of Iodine Deficiency in Children with Attention Deficit/Hyperactivity Disorder.
    Journal of clinical research in pediatric endocrinology, 2016, Mar-05, Volume: 8, Issue:1

    Topics: Adolescent; Attention Deficit Disorder with Hyperactivity; Biomarkers; Child; Child, Preschool; Fema

2016
Iodine deficiency--way to go yet.
    Lancet (London, England), 2008, Jul-12, Volume: 372, Issue:9633

    Topics: Child; Developing Countries; Humans; Intellectual Disability; Iodine; Sodium Chloride, Dietary

2008
An association study of the SLC26A4 gene in children with mental retardation.
    Neuroscience letters, 2009, Jul-03, Volume: 457, Issue:3

    Topics: Child; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Haplotypes;

2009
Investigation of iodine deficient state and iodine supplementation in patients with severe motor and intellectual disabilities on long-term total enteral nutrition.
    Endocrine journal, 2012, Volume: 59, Issue:8

    Topics: Adolescent; Adult; Child; Child, Preschool; Dietary Supplements; Enteral Nutrition; Female; Humans;

2012
[History of the endemic cretinism in Csallóköz, Hungary].
    Orvosi hetilap, 2012, Nov-04, Volume: 153, Issue:44

    Topics: Academic Dissertations as Topic; Congenital Hypothyroidism; Female; Goiter, Endemic; History, 18th C

2012
[STRUCTURAL AND NUMERICAL CHROMOSOME PATTERN (GROUP A AND E) IN A GIRL WITH THE PENDRED SYNDROME].
    Klinische Wochenschrift, 1963, Nov-01, Volume: 41

    Topics: Adolescent; Cell Division; Chromosome Aberrations; Chromosome Disorders; Chromosomes; Dwarfism; Fema

1963
Elevated serum proteinbound iodine values with dietary iodine deficiency.
    The Journal of clinical endocrinology and metabolism, 1962, Volume: 22

    Topics: Humans; Intellectual Disability; Iodine; Minerals; Thyroid Diseases

1962
[Frequency of subclinical hypothyroidism among healthy children and those with neurological conditions in the state of Mérida, Venezuela].
    Investigacion clinica, 2003, Volume: 44, Issue:3

    Topics: Autoantibodies; Child, Preschool; Comorbidity; Developmental Disabilities; Female; Humans; Hypothyro

2003
Positive association of the DIO2 (deiodinase type 2) gene with mental retardation in the iodine-deficient areas of China.
    Journal of medical genetics, 2004, Volume: 41, Issue:8

    Topics: Adolescent; Child; Child, Preschool; China; Female; Genetic Markers; Haplotypes; Humans; Intellectua

2004
Profile of iodine content of salt and urinary iodine excretion levels in selected districts of Tamil Nadu.
    Indian journal of pediatrics, 2004, Volume: 71, Issue:9

    Topics: Child; Child Nutritional Physiological Phenomena; Deficiency Diseases; Food, Fortified; Humans; Indi

2004
Lack of association of the thyroid transcription factor 1 gene with mental retardation in the iodine-deficient areas of China.
    Psychiatric genetics, 2005, Volume: 15, Issue:4

    Topics: Case-Control Studies; China; Humans; Intellectual Disability; Iodine; Nuclear Proteins; Thyroid Nucl

2005
[Effects of the iodine deficiency on intellectual variables among children].
    Psicothema, 2008, Volume: 20, Issue:2

    Topics: Adolescent; Catchment Area, Health; Child; Cognition Disorders; Female; Humans; Intellectual Disabil

2008
[Thyroid function in a mentally retarded child population of an iodine-deficient zone].
    Revista medica de Chile, 1984, Volume: 112, Issue:10

    Topics: Adolescent; Child; Female; Humans; Intellectual Disability; Iodine; Male; Thyroid Diseases; Thyroid

1984
Effects of iodine deficiency on mental and psychomotor abilities.
    American journal of physical anthropology, 1980, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Age Factors; Child; Congenital Hypothyroidism; Female; Goiter, Endemic; Humans; I

1980
From Papua New Guinea to the United Nations: the prevention of mental defect due to iodine deficiency.
    Australian journal of public health, 1995, Volume: 19, Issue:3

    Topics: Congenital Hypothyroidism; Humans; Intellectual Disability; International Cooperation; Iodine; Papua

1995
[Effects of iodine nutritional status of fetuses, infants and young children on their intelligence development in the areas with iodine-deficiency disorders].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1994, Volume: 28, Issue:6

    Topics: Child; China; Congenital Hypothyroidism; Female; Goiter, Endemic; Humans; Infant; Intellectual Disab

1994
Iodine deficiency disorders.
    Acta endocrinologica, 1993, Volume: 129, Issue:6

    Topics: Congenital Hypothyroidism; Global Health; Humans; Intellectual Disability; Iodine; Prevalence; Sodiu

1993
[Effects of high-dose iodine on brain development in mice].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1997, Volume: 31, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Female; Humans; Infant, Newborn; Intellectual Disability; Iodine;

1997
[PBI determination in malnourished children].
    Pediatria polska, 1977, Volume: 52, Issue:4

    Topics: Blood Proteins; Child, Preschool; Humans; Hypothyroidism; Infant; Intellectual Disability; Iodine; N

1977
Partial and total iodide organification defect in different sibships in a kindred.
    American journal of human genetics, 1977, Volume: 29, Issue:2

    Topics: Age Determination by Skeleton; Child; Diseases in Twins; Female; Goiter; Humans; Intellectual Disabi

1977
Endemic cretinism--a continuous personal educational experience during 10 years.
    Postgraduate medical journal, 1975, Volume: 51, Issue:599

    Topics: Adult; Child; Congenital Hypothyroidism; Deafness; Goiter, Endemic; Humans; Indonesia; Intellectual

1975
Clinical picture of endemic cretinism in central Apennines (Montefeltro).
    Thyroid : official journal of the American Thyroid Association, 1992,Winter, Volume: 2, Issue:4

    Topics: Adult; Aged; Congenital Hypothyroidism; Female; Gait; Humans; Hypothyroidism; Intellectual Disabilit

1992
Effects on school children of prophylaxis of mothers with iodized oil in an area of iodine deficiency.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:5

    Topics: Adolescent; Body Height; Body Weight; Child; Chronic Disease; Goiter, Endemic; Humans; Intellectual

1988
Neurological signs in congenital iodine-deficiency disorder (endemic cretinism).
    Developmental medicine and child neurology, 1985, Volume: 27, Issue:3

    Topics: Adolescent; Adult; Basal Ganglia Diseases; Child; Child, Preschool; Congenital Hypothyroidism; Deafn

1985
Congenital hypothyroidism with impaired thyroid response to thyrotropin.
    The New England journal of medicine, 1968, Nov-21, Volume: 279, Issue:21

    Topics: Amino Acids; Animals; Biopsy; Carbon Isotopes; Cattle; Centrifugation; Centrifugation, Density Gradi

1968
Thyroid function in human pregnancy. V. Incidence of maternal serum low butanol-extractable iodines and of normal gestational TBG and TBPA capacities; retardation of 8-month-old infants.
    American journal of obstetrics and gynecology, 1969, Jul-15, Volume: 104, Issue:6

    Topics: Abortion, Spontaneous; Adolescent; Adult; Birth Weight; Female; Fetal Death; Growth; Growth Disorder

1969
The neck-thigh radioiodine ratio in mongolism.
    Journal of mental deficiency research, 1967, Volume: 11, Issue:2

    Topics: Acrocephalosyndactylia; Angiomatosis; Brain Diseases; Child; Child, Preschool; Diabetes Insipidus; D

1967
History of iodine prophylaxis with regard to cretinism and deaf-mutism.
    Advances in experimental medicine and biology, 1972, Volume: 30

    Topics: Congenital Hypothyroidism; Deafness; History, 20th Century; Humans; Intellectual Disability; Iodine;

1972
Intellectual assessment in primitive societies, with a preliminary report of a study of the effects of early iodine supplementation on intelligence.
    Advances in experimental medicine and biology, 1972, Volume: 30

    Topics: Child, Preschool; Congenital Hypothyroidism; Culture; Ecuador; Female; Gestational Age; Goiter, Ende

1972
The clinical pattern of endemic cretinism in Papua, New Guinea.
    Advances in experimental medicine and biology, 1972, Volume: 30

    Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Deafness; Electrocardiography; Femal

1972
[Familial goiter accompanying amblyacousia and idiocy].
    Horumon to rinsho. Clinical endocrinology, 1973, Volume: 21, Issue:2

    Topics: Adolescent; Adult; Child; Deafness; Female; Goiter; Humans; Intellectual Disability; Iodine; Male; M

1973
[Multiendocrine changes in patients with neurological lesions].
    Actualites endocrinologiques, 1973, Volume: 13, Issue:0

    Topics: Adrenal Glands; Adult; Circadian Rhythm; Humans; Hydrocortisone; Intellectual Disability; Iodine; Mi

1973
The varied manifestations of endemic cretinism.
    Transactions of the American Clinical and Climatological Association, 1974, Volume: 85

    Topics: Adolescent; Adult; Bone Development; Congenital Hypothyroidism; Deafness; Democratic Republic of the

1974
Deaf-mutes with mental illness. (A longitudinal study).
    Acta psychiatrica Scandinavica. Supplementum, 1969, Volume: 210

    Topics: Adolescent; Adult; Aged; Aphasia; Brain Diseases; Cerebral Cortex; Child; Child, Preschool; Communic

1969
[Clinical features of endemic degeneration in 2 Czech regions].
    Vnitrni lekarstvi, 1968, Volume: 14, Issue:12

    Topics: Adolescent; Adult; Child; Congenital Hypothyroidism; Czechoslovakia; Goiter; Humans; Intellectual Di

1968
Endemic goiter and endemic cretinism in the Andean region.
    The New England journal of medicine, 1969, Feb-06, Volume: 280, Issue:6

    Topics: Adult; Altitude; Child; Congenital Hypothyroidism; Deafness; Deficiency Diseases; Dwarfism; Ecuador;

1969
Substance use in individuals with mild to borderline intellectual disability: A comparison between self-report, collateral-report and biomarker analysis.
    Research in developmental disabilities, 2017, Volume: 63

    Topics: Adult; Alcohol Drinking; Amphetamine-Related Disorders; Amphetamines; Biomarkers; Cocaine; Cocaine-R

2017
Sweat osmolality in some of the congenital diseases.
    Indian journal of pathology & microbiology, 1993, Volume: 36, Issue:4

    Topics: Adolescent; Adult; Age Factors; Child; Cystic Fibrosis; Down Syndrome; Female; Humans; Intellectual

1993
Congenital sensory neuropathy with anhidrosis.
    Archives of disease in childhood, 1968, Volume: 43, Issue:227

    Topics: Acetylcholine; Chlorides; Consanguinity; Epinephrine; Humans; Infant; Intellectual Disability; Male;

1968
Familial epilepsy and yellow teeth--a disease of the CNS associated with enamel hypoplasia.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:4

    Topics: Axons; Brain; Brain Chemistry; Child; Child, Preschool; Chlorides; Cytoplasm; Dental Enamel Hypoplas

1974
[Nephrogenic diabetes].
    Minerva pediatrica, 1973, Aug-14, Volume: 25, Issue:27

    Topics: Adolescent; Blood Cell Count; Child; Child, Preschool; Cholesterol; Diabetes Insipidus; Diagnosis, D

1973
A new type of idiopathic hyperglycinemia with hypo-oxaluria.
    Pediatrics, 1965, Volume: 36, Issue:6

    Topics: Amino Acid Metabolism, Inborn Errors; Blood; Cerebrospinal Fluid; Child, Preschool; Chromatography;

1965