Page last updated: 2024-10-18

iodine and Infant, Premature, Diseases

iodine has been researched along with Infant, Premature, Diseases in 20 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Infant, Premature, Diseases: Diseases that occur in PREMATURE INFANTS.

Research Excerpts

ExcerptRelevanceReference
"Hypothyroidism was diagnosed in 6 of the 8 preterm and in 1 of the 7 term newborns of group 2."5.27Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care. ( Beyer, P; Grüters, A; l'Allemand, D; Weber, B, 1987)
"In neonates, iatrogenic hypothyroidism can result from topical or IV iodine exposure."3.88Early Identification of Primary Hypothyroidism in Neonates Exposed to Intralymphatic Iodinated Contrast: A Case Series. ( Breault, DT; Cherella, CE; Levine, BS; Smith, JR; Thaker, V, 2018)
"Premature newborns are particularly vulnerable to iatrogenic hypothyroidism due to iodine exposure, usually through skin absorption of iodine-containing disinfectants or intravenous administration of iodinated contrast agents."3.75Severe hypothyroidism after contrast enema in premature infants. ( Cambonie, G; Dalla-Vale, F; Lombard, F; Picaud, JC; Plan, O; Veyrac, C, 2009)
" More than 50% of the babies with transient hypothyroidism had been exposed to iodine; maternal transfer of antibodies had occurred in a third of them."3.70Neonatal transient hypothyroidism: aetiological study. Italian Collaborative Study on Transient Hypothyroidism. ( Bona, G; Chiumello, G; Rapa, A; Vigone, MC; Weber, G, 1998)
" Transient hypothyroxinemia (T4 less than 60 nmol/l) could be diagnosed in 18 infants, but no one had hypothyroidism in sick prematures after injection of iodine containing contrast agents seems to be lower than expected."3.67[Iodine burden in premature infants in roentgenologically controlled positioning of central venous silastic catheters]. ( Adams, G; Frasch, W; Preissler, E; Saule, H, 1986)
"Hypothyroidism was diagnosed in 6 of the 8 preterm and in 1 of the 7 term newborns of group 2."1.27Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care. ( Beyer, P; Grüters, A; l'Allemand, D; Weber, B, 1987)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19908 (40.00)18.7374
1990's2 (10.00)18.2507
2000's5 (25.00)29.6817
2010's4 (20.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Williams, FLR1
Lindgren, A1
Watson, J1
Boelen, A1
Cheetham, T1
Cherella, CE1
Breault, DT1
Thaker, V1
Levine, BS1
Smith, JR1
Chapman, AK1
Farmer, ZJ1
Mastrandrea, LD1
Matlock, KA1
Min, H1
Dong, J1
Wang, Y2
Teng, W1
Xi, Q1
Chen, J1
Lombard, F1
Dalla-Vale, F1
Veyrac, C1
Plan, O1
Cambonie, G1
Picaud, JC1
Ahmet, A1
Lawson, ML1
Babyn, P1
Tricco, AC1
La Gamma, EF1
van Wassenaer, AG1
Ares, S2
Golombek, SG1
Kok, JH1
Quero, J2
Hong, T1
Rahbar, MH1
de Escobar, GM2
Fisher, DA2
Paneth, N1
Lahmiti, S1
El Fakiri, K1
Aboussad, A1
Ibrahim, M1
Visser, TJ1
Durán, S1
van Toor, H1
Strachan, J1
Williams, FL1
Hume, R1
Smith, VC1
Svoren, BM1
Wolfsdorf, JI1
Delange, F1
Dalhem, A1
Bourdoux, P1
Lagasse, R1
Glinoer, D1
Walfish, PG1
Ermans, AM1
Pastor, I1
Morreale de Escobar, G1
Weber, G1
Vigone, MC1
Rapa, A1
Bona, G1
Chiumello, G1
l'Allemand, D1
Grüters, A1
Beyer, P1
Weber, B1
Ryan, CA1
Hallgren, RA1
Finer, NN1
Saule, H1
Preissler, E1
Frasch, W1
Adams, G1
Orbeck, H1
Beckmann, G1
Keresztury, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Thyroid Function in Children With Congenital Heart Disease[NCT03496363]50 participants (Anticipated)Observational2018-05-01Not yet recruiting
The Therapeutic Role of Gastrografin for Treating Small Bowel Obstruction in Children: A Multi-Centre Canadian Prospective Study[NCT03573921]Phase 2/Phase 32 participants (Actual)Interventional2019-09-01Terminated (stopped due to Poor recruitment to date.)
Phase III Study of Thyroid Hormones in Prematures[NCT02103998]Phase 30 participants (Actual)Interventional2020-07-01Withdrawn (stopped due to not funded by NIH)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for iodine and Infant, Premature, Diseases

ArticleYear
Neonatal Thyroid Function and Disorders.
    Clinical obstetrics and gynecology, 2019, Volume: 62, Issue:2

    Topics: Drug-Related Side Effects and Adverse Reactions; Fetal Development; Humans; Infant, Newborn; Infant,

2019
Maternal Hypothyroxinemia-Induced Neurodevelopmental Impairments in the Progeny.
    Molecular neurobiology, 2016, Volume: 53, Issue:3

    Topics: Brain; Cohort Studies; Endocrine Disruptors; Female; Forecasting; Humans; Infant, Newborn; Infant, P

2016
Hypothyroidism in neonates post-iodinated contrast media: a systematic review.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:10

    Topics: Contrast Media; Controlled Clinical Trials as Topic; Female; Humans; Hypothyroidism; Infant, Newborn

2009
Hypothyroidism in neonates post-iodinated contrast media: a systematic review.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:10

    Topics: Contrast Media; Controlled Clinical Trials as Topic; Female; Humans; Hypothyroidism; Infant, Newborn

2009
Hypothyroidism in neonates post-iodinated contrast media: a systematic review.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:10

    Topics: Contrast Media; Controlled Clinical Trials as Topic; Female; Humans; Hypothyroidism; Infant, Newborn

2009
Hypothyroidism in neonates post-iodinated contrast media: a systematic review.
    Acta paediatrica (Oslo, Norway : 1992), 2009, Volume: 98, Issue:10

    Topics: Contrast Media; Controlled Clinical Trials as Topic; Female; Humans; Hypothyroidism; Infant, Newborn

2009
[Antiseptics in neonatology: the inheritance of the past in the daylight].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2010, Volume: 17, Issue:1

    Topics: Administration, Cutaneous; Anti-Infective Agents, Local; Chlorhexidine; Humans; Infant, Newborn; Inf

2010
Increased risk of primary hypothyroidism in preterm infants.
    The Journal of pediatrics, 1984, Volume: 105, Issue:3

    Topics: Belgium; Female; Humans; Hypothyroidism; Infant, Newborn; Infant, Premature, Diseases; Iodine; Longi

1984

Trials

1 trial available for iodine and Infant, Premature, Diseases

ArticleYear
Phase 1 trial of 4 thyroid hormone regimens for transient hypothyroxinemia in neonates of <28 weeks' gestation.
    Pediatrics, 2009, Volume: 124, Issue:2

    Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up

2009

Other Studies

14 other studies available for iodine and Infant, Premature, Diseases

ArticleYear
Thyroid function in preterm infants and neurodevelopment at 2 years.
    Archives of disease in childhood. Fetal and neonatal edition, 2020, Volume: 105, Issue:5

    Topics: Child Development; Child, Preschool; Cognitive Dysfunction; Female; Gestational Age; Humans; Infant,

2020
Early Identification of Primary Hypothyroidism in Neonates Exposed to Intralymphatic Iodinated Contrast: A Case Series.
    The Journal of clinical endocrinology and metabolism, 2018, 10-01, Volume: 103, Issue:10

    Topics: Anti-Infective Agents, Local; Contrast Media; Female; Humans; Hypothyroidism; Infant; Infant, Newbor

2018
Severe hypothyroidism after contrast enema in premature infants.
    European journal of pediatrics, 2009, Volume: 168, Issue:4

    Topics: Cholestasis; Contrast Media; Enema; Goiter; Humans; Hypothyroidism; Iatrogenic Disease; Infant, Extr

2009
Iodine deficiency associated with parenteral nutrition in extreme preterm infants.
    Archives of disease in childhood. Fetal and neonatal edition, 2003, Volume: 88, Issue:1

    Topics: Age Factors; Digestive System; Female; Humans; Infant, Newborn; Infant, Premature, Diseases; Intesti

2003
Hypothyroidism in a breast-fed preterm infant resulting from maternal topical iodine exposure.
    The Journal of pediatrics, 2006, Volume: 149, Issue:4

    Topics: Administration, Topical; Breast Feeding; Female; Humans; Hypothyroidism; Infant, Newborn; Infant, Pr

2006
Thyroid complications, including overt hypothyroidism, related to the use of non-radiopaque silastic catheters for parenteral feeding in prematures requiring injection of small amounts of an iodinated contrast medium.
    Acta paediatrica (Oslo, Norway : 1992), 1995, Volume: 84, Issue:5

    Topics: Catheterization; Contrast Media; Humans; Hypothyroidism; Infant, Newborn; Infant, Premature; Infant,

1995
Neonatal transient hypothyroidism: aetiological study. Italian Collaborative Study on Transient Hypothyroidism.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Antibodies; Contrast Media; Female; Humans; Hypothyroidism; Inf

1998
Iodine in contrast agents and skin disinfectants is the major cause for hypothyroidism in premature infants during intensive care.
    Hormone research, 1987, Volume: 28, Issue:1

    Topics: Contrast Media; Critical Care; Disinfectants; Humans; Hypothyroidism; Infant, Newborn; Infant, Prema

1987
The use of povidone iodine in neonatal bowel surgery.
    Journal of pediatric surgery, 1987, Volume: 22, Issue:4

    Topics: Humans; Ileostomy; Infant, Newborn; Infant, Premature, Diseases; Iodine; Postoperative Period; Povid

1987
[Iodine burden in premature infants in roentgenologically controlled positioning of central venous silastic catheters].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:1

    Topics: Angiography; Body Burden; Catheters, Indwelling; Humans; Hypothyroidism; Infant, Newborn; Infant, Pr

1986
Neonatal hyperthyroidism.
    Acta paediatrica Scandinavica, 1973, Volume: 62, Issue:3

    Topics: Adult; Body Weight; Breast Diseases; Diarrhea; Digitalis Glycosides; Female; Graves Disease; Humans;

1973
[Etiologic problems of hearing disorders in "risk children"].
    HNO, 1969, Volume: 17, Issue:8

    Topics: Abnormalities, Drug-Induced; Chromosome Aberrations; Chromosome Disorders; Consanguinity; Deafness;

1969
[Congenital goiters].
    Gegenbaurs morphologisches Jahrbuch, 1968, Volume: 111, Issue:4

    Topics: Birth Weight; Female; Fetal Death; Goiter; Humans; Hungary; Infant, Newborn; Infant, Premature, Dise

1968
Diagnosis of cystic fibrosis in premature infants.
    Lancet (London, England), 1987, Jan-03, Volume: 1, Issue:8523

    Topics: Adult; Child; Cystic Fibrosis; Electrolytes; Humans; Infant, Newborn; Infant, Premature, Diseases; S

1987