Page last updated: 2024-10-18

iodine and Hyperplasia

iodine has been researched along with Hyperplasia in 79 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Hyperplasia: An increase in the number of cells in a tissue or organ without tumor formation. It differs from HYPERTROPHY, which is an increase in bulk without an increase in the number of cells.

Research Excerpts

ExcerptRelevanceReference
"While the concept of iodine deficiency (ID) still dominates most discussions about the pathogenesis of multinodular goiter (MNG), the present review focuses on those mechanisms that may cause MNG in the absence of ID."8.81Nodular goiter and goiter nodules: Where iodine deficiency falls short of explaining the facts. ( Derwahl, M; Studer, H, 2001)
"Thirty-three thyroid specimens obtained from 28 patients with clinically and laboratory-proven iodine-induced hypothyroidism were examined clinically, histologically, immunohistochemically, and ultrastructurally."7.68Iodine-induced hypothyroidism: a clinical and histological study of 28 patients. ( Hashimoto, T; Matsubara, F; Michigishi, T; Mizukami, Y; Nonomura, A; Takazakura, E; Tonami, N, 1993)
"Involution of thyroid hyperplasia was induced in mice by discontinuing a goitrogenic treatment (low iodine diet plus 0."7.67Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution. ( Beckers, C; Cornette, C; Denef, JF; Haumont, S; Many, MC; van den Hove-Vandenbroucke, MF, 1985)
"Necrosis was associated with transient infiltration of inflammatory cells."5.29Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism. ( Contempre, B; Denef, JF; Dumont, JE; Many, MC, 1995)
"Thyroid hyperplasia was induced by a low iodine diet supplemented with 0."5.27Increased follicular heterogeneity in experimental colloid goiter produced by refeeding iodine excess after thyroid hyperplasia. ( Denef, JF; Hamudi, S; Haumont, S; Many, MC, 1986)
"The most frequent cause of goiter in children is a deficit of iodine, leading to endemia of goiter in the regions with insufficient supplementation of this element."4.83[Current views on the etiopathogenesis of goiter in children]. ( Brzozowska, M; Kretowski, A, 2006)
"While the concept of iodine deficiency (ID) still dominates most discussions about the pathogenesis of multinodular goiter (MNG), the present review focuses on those mechanisms that may cause MNG in the absence of ID."4.81Nodular goiter and goiter nodules: Where iodine deficiency falls short of explaining the facts. ( Derwahl, M; Studer, H, 2001)
" The intrathyroidal iodine deficiency itself and the increased activity of local growth factors, however, may be the main causes of initiation, promotion and maintenance of hyperplasia."4.79Thyroxine treatment of benign goiter. ( Gärtner, R, 1994)
"Iodine excess and resultant hyperplastic goiter are well documented in neonatal ruminants, but little is reported on iodine excess in adult ruminants and associated histological changes of the thyroid gland."3.80Hyperplastic goiter in two adult dairy cows. ( Fitzgerald, SD; Herdt, TH; Ong, CB, 2014)
"FDS with iodine staining was superior to conventional FDS for the diagnosis of DIN and is valuable for breast cancer prevention."3.79Diagnostic accuracy of fiberoptic ductoscopy plus in vivo iodine staining for intraductal proliferative lesions. ( Feng, XZ; Jiang, CW; Mei, H; Song, YH; Zhang, FX; Zhao, B, 2013)
"The present study aimed to investigate the effect of smoking on thyroid nodule formation and goiter development in healthy subjects living in Istanbul, an iodine-sufficient region."3.78Does smoking affect thyroid gland enlargement and nodule formation in iodine-sufficient regions? ( Demirtunc, R; Karatoprak, C; Kartal, I; Kayatas, K; Meric, K; Ozdemir, A; Yolbas, S, 2012)
" Expression of the sodium iodide symporter (NIS), a gene essential to the radioiodine ablation of thyroid hyperplasia, neoplasia, and metastasis, was also potently inhibited in PBF-Tg mice."3.77Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment. ( Boelaert, K; Eggo, MC; Fong, JC; Franklyn, JA; Gentilin, E; Knauf, JA; Leadbeater, WE; Lewy, GD; McCabe, CJ; Read, ML; Seed, RI; Sharma, N; Smith, VE; Warfield, A; Watkinson, JC, 2011)
"Certain types of varicose veins can be successfully sclerosed with polyiodinated iodine (PII)."3.69Clinical and histologic evaluation of polyiodinated iodine with and without hypertonic saline/dextrose in the rabbit ear vein model. ( Goldman, MP; Raymond-Martimbeau, P, 1997)
"Thirty-three thyroid specimens obtained from 28 patients with clinically and laboratory-proven iodine-induced hypothyroidism were examined clinically, histologically, immunohistochemically, and ultrastructurally."3.68Iodine-induced hypothyroidism: a clinical and histological study of 28 patients. ( Hashimoto, T; Matsubara, F; Michigishi, T; Mizukami, Y; Nonomura, A; Takazakura, E; Tonami, N, 1993)
"Involution of thyroid hyperplasia was induced in mice by discontinuing a goitrogenic treatment (low iodine diet plus 0."3.67Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution. ( Beckers, C; Cornette, C; Denef, JF; Haumont, S; Many, MC; van den Hove-Vandenbroucke, MF, 1985)
"Involution of thyroid hyperplasia was induced in C3H mice by discontinuing a goitrogenic treatment (low iodine diet supplemented with 0."3.66Morphological and functional changes during thyroid hyperplasia and involution in C3H Mice: evidence for folliculoneogenesis during involution. ( Denef, JF; Gathy, P; Haumont, S; Many, MC, 1983)
"Iodine concentration was undetectable in nonozonized water (<0."1.56A CLUSTER OF CASES OF THYROID HYPERPLASIA IN AQUARIUM-HOUSED TROPICAL MARINE TELEOSTS FOLLOWING A CHANGE OF SALT MIX BRAND. ( Jalenques, M; Lair, S; St-Cyr, JF; Summa, N; Vergneau-Grosset, C; Youcef, WA, 2020)
"Necrosis was associated with transient infiltration of inflammatory cells."1.29Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism. ( Contempre, B; Denef, JF; Dumont, JE; Many, MC, 1995)
"Thyroid hyperplasia was induced by a low iodine diet supplemented with 0."1.27Increased follicular heterogeneity in experimental colloid goiter produced by refeeding iodine excess after thyroid hyperplasia. ( Denef, JF; Hamudi, S; Haumont, S; Many, MC, 1986)

Research

Studies (79)

TimeframeStudies, this research(%)All Research%
pre-199049 (62.03)18.7374
1990's10 (12.66)18.2507
2000's10 (12.66)29.6817
2010's7 (8.86)24.3611
2020's3 (3.80)2.80

Authors

AuthorsStudies
Morikawa, T1
Shibahara, T1
Takano, M1
Honglian, Y1
Huanliang, L1
Wei, Z1
Xiaojun, S1
Xiujie, G1
Kefeng, M1
Kun, W1
Bo, C1
Yanjun, F1
Zhuge, X1
Jalenques, M1
Vergneau-Grosset, C1
Summa, N1
Youcef, WA1
St-Cyr, JF1
Lair, S1
Murray, KN1
Wolf, JC1
Spagnoli, ST1
Lains, D1
Budrow, N1
Kent, ML1
Feng, XZ1
Song, YH1
Zhang, FX1
Jiang, CW1
Mei, H1
Zhao, B1
Ong, CB1
Herdt, TH1
Fitzgerald, SD1
Chandra, AK1
Mondal, C1
Sinha, S1
Chakraborty, A1
Pearce, EN1
Kayes, TD1
Weisman, GA1
Camden, JM1
Woods, LT1
Bredehoeft, C1
Downey, EF1
Cole, J1
Braley-Mullen, H1
Read, ML1
Lewy, GD1
Fong, JC1
Sharma, N1
Seed, RI1
Smith, VE1
Gentilin, E1
Warfield, A1
Eggo, MC1
Knauf, JA1
Leadbeater, WE1
Watkinson, JC1
Franklyn, JA1
Boelaert, K1
McCabe, CJ1
Karatoprak, C1
Kartal, I1
Kayatas, K1
Ozdemir, A1
Yolbas, S1
Meric, K1
Demirtunc, R1
BILLION, H2
KUHNE, P3
MALOOF, F1
FOLLIS, RH2
SCHALLER, RT1
STEVENSON, JK1
KARKINS, HN1
Georgopoulos, NA1
Sykiotis, GP1
Sgourou, A1
Papachatzopoulou, A1
Markou, KB1
Kyriazopoulou, V1
Papavassiliou, AG1
Vagenakis, AG1
D'ANGELO, SA1
PASCHKIS, KE1
CANTAROW, A1
SIEGEL, AN1
RIVERO FONTAN, JL1
SAYE, EB1
WATT, CH1
FOUSHEE, JC1
PALMER, JI1
Weber, G1
Vigone, MC1
Passoni, A1
Odoni, M1
Paesano, PL1
Dosio, F1
Proverbio, MC1
Corbetta, C1
Persani, L1
Chiumello, G1
Brzozowska, M1
Kretowski, A1
Lee, SH1
Kwon, HS1
Yoo, IR1
Park, HJ1
Yoon, KH1
Cha, BY1
Son, HY2
Greer, MA1
Studer, H5
Kendall, JW1
Denef, JF7
Haumont, S6
Beckers, C4
Aleshin, BV1
Ramelli, F1
Rognoni, JB4
Penel, C4
Ducret, F1
Many, MC5
Gathy, P1
Tachiwaki, O1
Wollman, SH2
Valenta, LJ1
Florsheim, WC1
Sharma, BS1
Doige, CE1
McLaughlin, BG1
Cornette, C2
Cordier, AC1
Contempre, B1
Dumont, JE4
Fang, WT1
Qao, BS1
Wang, JB1
Gärtner, R2
Mizukami, Y1
Michigishi, T1
Nonomura, A1
Hashimoto, T1
Tonami, N1
Matsubara, F1
Takazakura, E1
Hotz, KJ1
Wilson, AG1
Thake, DC1
Roloff, MV1
Capen, CC2
Kronenberg, JM1
Brewster, DW1
Sagartz, JE1
Jhiang, SM1
Tong, Q1
Goldman, MP1
Raymond-Martimbeau, P1
Ketai, LH1
Muggenberg, BA1
McIntire, GL1
Bacon, ER1
Rosenberg, R1
Losco, PE1
Toner, JL1
Nikula, KJ1
Haley, P1
Ikeda, T2
Nishikawa, A2
Imazawa, T2
Kimura, S2
Hirose, M3
Takegawa, K2
Sakamori, M1
Koremoto, M1
Yamada, T1
Takagi, S1
Takeuchi, M1
Yanai, T1
Masegi, T1
Mitsumori, K2
Yasuhara, K1
Koujitani, T1
Nasu, M1
Onodera, H1
Takagi, H1
Nakamura, H1
Miyauchi, M1
Derwahl, M1
Corvilain, B1
Van Sande, J1
Vassart, G1
Jemec, B1
Sonstegard, R1
Leatherland, JF1
Graham, SL2
Davis, KJ1
Hansen, WH2
Graham, CH1
David, JS1
Fujimoto, N1
Sakai, Y1
Ito, A1
Smyth, JA1
McNamee, PT1
Kennedy, DG1
McCullough, SJ1
Logan, EF1
Ellis, WA1
Golstein, J2
Galand, P2
Bastiani, P1
Roccabianca, M1
Lemarchand-Beraud, T1
Kalinin, AP1
Levit, ID1
Stübner, D1
Greil, W1
Gropper, K1
Brabant, G1
Permanetter, W1
Horn, K1
Pickardt, CR1
Hamudi, S1
van den Hove-Vandenbroucke, MF1
Consden, R1
Doble, A1
Glynn, LE1
Nind, AP1
Kreines, K1
Esselborn, VM1
Binswanger, C1
Kohler, H2
Steiger, J1
Brun del Re, R1
Köbberling, J1
Sidorenko, LN1
Shal'neva, TS1
Lederer, J1
Bürgi, H1
Radvila, A1
Yamamoto, K1
DeGroot, LJ1
Shoemaker, JP1
Hoffman, RV1
Walsh, EL1
Blair, B1
Aquino, TI1
Eskin, BA1
Noel, A1
Harbitz, TB1
Beck, JS2
Olen, E1
Johansson, H1
Nylander, G1
Breitman, TR1
Nicol, AG1
Thomson, JA1
McGirr, EM1

Reviews

8 reviews available for iodine and Hyperplasia

ArticleYear
[Current views on the etiopathogenesis of goiter in children].
    Endokrynologia, diabetologia i choroby przemiany materii wieku rozwojowego : organ Polskiego Towarzystwa Endokrynologow Dzieciecych, 2006, Volume: 12, Issue:1

    Topics: Child; Environmental Exposure; Goiter; Goiter, Endemic; Graves Disease; Hashimoto Disease; Humans; H

2006
[Pathogenetic problems of goiter].
    Arkhiv patologii, 1981, Volume: 43, Issue:4

    Topics: Adaptation, Physiological; Animals; APUD Cells; Cell Division; Epithelium; Goiter; Humans; Hyperplas

1981
Simple goiter and its variants: euthyroid and hyperthyroid multinodular goiters.
    Endocrine reviews, 1982,Winter, Volume: 3, Issue:1

    Topics: Animals; Blood Vessels; Connective Tissue; Cyclic AMP; DNA; Goiter; Goiter, Nodular; Graves Disease;

1982
Thyroxine treatment of benign goiter.
    Acta medica Austriaca, 1994, Volume: 21, Issue:2

    Topics: Animals; Goiter, Endemic; Growth Substances; Humans; Hyperplasia; Iodine; Rats; Thyroid Gland; Thyro

1994
Nodular goiter and goiter nodules: Where iodine deficiency falls short of explaining the facts.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2001, Volume: 109, Issue:5

    Topics: Female; Goiter, Nodular; Gonadal Steroid Hormones; Humans; Hyperplasia; Iodine; Male; Thyroid Gland;

2001
Somatic and germline mutations of the TSH receptor and thyroid diseases.
    Clinical endocrinology, 2001, Volume: 55, Issue:2

    Topics: Animals; Cyclic AMP; Dogs; Genotype; Germ-Line Mutation; Humans; Hyperplasia; Hyperthyroidism; Iodin

2001
[Current aspects of the autoimmune thyroiditis problem].
    Terapevticheskii arkhiv, 1985, Volume: 57, Issue:9

    Topics: Adult; Autoimmune Diseases; Chromosome Aberrations; Female; Goiter, Endemic; Goiter, Nodular; Graves

1985
[Genetic aspects of endocrine diseases].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1974, Volume: 80

    Topics: Adolescent; Adrenal Cortex; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Hyperplasia, Co

1974

Other Studies

71 other studies available for iodine and Hyperplasia

ArticleYear
Combination of fluorescence visualization and iodine solution-guided surgery for local control of early tongue cancer.
    International journal of oral and maxillofacial surgery, 2023, Volume: 52, Issue:2

    Topics: Carcinoma, Squamous Cell; Disease-Free Survival; Humans; Hyperplasia; Iodine; Mouth Neoplasms; Neopl

2023
Thyroid-disrupting effects and mechanism of thiazole-Zn-induced thyroid cell hypertrophy and hyperplasia in male Sprague-Dawley rats.
    Ecotoxicology and environmental safety, 2020, Jun-15, Volume: 196

    Topics: Animals; China; Coordination Complexes; Fungicides, Industrial; Hyperplasia; Hypertrophy; Iodine; Io

2020
A CLUSTER OF CASES OF THYROID HYPERPLASIA IN AQUARIUM-HOUSED TROPICAL MARINE TELEOSTS FOLLOWING A CHANGE OF SALT MIX BRAND.
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2020, Volume: 51, Issue:3

    Topics: Animals; Animals, Zoo; Fishes; Hyperplasia; Iodine; Smegmamorpha; Thyroid Gland

2020
Reversibility of Proliferative Thyroid Lesions Induced by Iodine Deficiency in a Laboratory Zebrafish Colony.
    Zebrafish, 2018, Volume: 15, Issue:6

    Topics: Adenoma; Animals; Diet; Female; Hyperplasia; Iodine; Male; Thyroid Gland; Thyroid Neoplasms; Zebrafi

2018
Diagnostic accuracy of fiberoptic ductoscopy plus in vivo iodine staining for intraductal proliferative lesions.
    Chinese medical journal, 2013, Volume: 126, Issue:16

    Topics: Adult; Aged; Breast; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Intraductal, Noninfiltr

2013
Hyperplastic goiter in two adult dairy cows.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2014, Volume: 26, Issue:6

    Topics: Animals; Cattle; Cattle Diseases; Female; Goiter; Hyperplasia; Iodine; Michigan; Sodium Chloride, Di

2014
Synergic actions of polyphenols and cyanogens of peanut seed coat (Arachis hypogaea) on cytological, biochemical and functional changes in thyroid.
    Indian journal of experimental biology, 2015, Volume: 53, Issue:3

    Topics: Animal Feed; Animals; Antithyroid Agents; Arachis; Drug Synergism; Glucosides; Hyperplasia; Hypertro

2015
New Murine Model of Early Onset Autoimmune Thyroid Disease/Hypothyroidism and Autoimmune Exocrinopathy of the Salivary Gland.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 09-15, Volume: 197, Issue:6

    Topics: Animals; Autoimmune Diseases; CD28 Antigens; CD40 Antigens; Cells, Cultured; Disease Models, Animal;

2016
Proto-oncogene PBF/PTTG1IP regulates thyroid cell growth and represses radioiodide treatment.
    Cancer research, 2011, Oct-01, Volume: 71, Issue:19

    Topics: Animals; Cell Proliferation; Cyclin D1; Gene Expression Regulation; Goiter, Nodular; Humans; Hyperpl

2011
Does smoking affect thyroid gland enlargement and nodule formation in iodine-sufficient regions?
    Annales d'endocrinologie, 2012, Volume: 73, Issue:6

    Topics: Adult; Aged; Female; Geography; Goiter; Humans; Hyperplasia; Iodine; Male; Middle Aged; Models, Biol

2012
[The value of various radioiodine tests for the differential diagnosis of thyroid gland disorders; with a contribution to active hyperplasia].
    Zeitschrift fur klinische Medizin, 1954, Volume: 152, Issue:5

    Topics: Diagnosis, Differential; Humans; Hyperplasia; Iodine; Iodine Radioisotopes; Radioisotopes; Thyroid D

1954
The effect of hypophysectomy and of thyroxine on the radiation-induced changes in the rat thyroid.
    Endocrinology, 1955, Volume: 56, Issue:2

    Topics: Animals; Hyperplasia; Hypertrophy; Hypophysectomy; Iodine; Iodine Radioisotopes; Pituitary Gland; Ra

1955
[Iodine requirements in various forms of thyroid function, with a contribution on the etiology of compensated hyperplasia].
    Arztliche Wochenschrift, 1955, Oct-07, Volume: 10, Issue:40

    Topics: Humans; Hyperplasia; Hyperthyroidism; Iodides; Iodine

1955
STUDIES ON IODINATED PROTEINS IN EXPERIMENTAL HYPERPLASTIC AND COLLOID GOITERS OF HAMSTERS.
    Laboratory investigation; a journal of technical methods and pathology, 1963, Volume: 12

    Topics: Centrifugation; Colloids; Cricetinae; Goiter; Hyperplasia; Immunoelectrophoresis; Iodine; Metabolism

1963
DEVELOPMENT OF CARCINOMA OF THE THYROID IN MICE.
    Surgical forum, 1964, Volume: 15

    Topics: Animals; Carcinoma; Deficiency Diseases; Hyperplasia; Hypertrophy; Iodine; Mice; Neoplasms; Patholog

1964
FURTHER OBSERVATIONS ON THYROIDITIS AND COLLOID ACCUMULATION IN HYPERPLASTIC THYROID GLANDS OF HAMSTERS RECEIVING EXCESS IODINE.
    Laboratory investigation; a journal of technical methods and pathology, 1964, Volume: 13

    Topics: Animals; Colloids; Cortisone; Cricetinae; Goiter; Hyperplasia; Hyperthyroidism; Iodine; Pharmacology

1964
[Compensatory active hyperplasia of thyroid gland and its radioiodine diagnosis].
    Arztliche Forschung, 1955, Apr-10, Volume: 9, Issue:4

    Topics: Disease; Goiter; Humans; Hyperplasia; Iodine; Iodine Radioisotopes; Radioisotopes; Thyroid Diseases;

1955
Autonomously functioning thyroid nodules in a former iodine-deficient area commonly harbor gain-of-function mutations in the thyrotropin signaling pathway.
    European journal of endocrinology, 2003, Volume: 149, Issue:4

    Topics: Adenoma; Adult; Aged; Endemic Diseases; Female; Goiter, Nodular; Greece; Heterotrimeric GTP-Binding

2003
Hyperplasia and I131 uptake of the guinea pig thyroid during and after chronic propylthiouracil treatment.
    Endocrinology, 1951, Volume: 49, Issue:5

    Topics: Guinea Pigs; Hyperplasia; Iodides; Iodine; Iodine Radioisotopes; Propylthiouracil; Thiouracil; Thyro

1951
Congenital thyroid hyperplasia in twins; report of a case following administration of thiouracil and iodine to mother during pregnancy.
    Journal of the American Medical Association, 1952, Aug-09, Volume: 149, Issue:15

    Topics: Disease; Female; Goiter; Humans; Hyperplasia; Infant; Infant, Newborn; Infant, Newborn, Diseases; Io

1952
Congenital hypothyroidism with gland in situ: diagnostic re-evaluation.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:6

    Topics: Congenital Hypothyroidism; Female; Humans; Hyperplasia; Hypothyroidism; Infant, Newborn; Iodine; Mal

2005
False-positive iodine uptake in thymic hyperplasia on diagnostic I-123 whole-body scan after total thyroidectomy.
    Clinical nuclear medicine, 2007, Volume: 32, Issue:2

    Topics: False Positive Reactions; Female; Humans; Hyperplasia; Iodine; Iodine Radioisotopes; Middle Aged; Ra

2007
Studies on the pathogenesis of colloid goiter.
    Endocrinology, 1967, Volume: 81, Issue:3

    Topics: Animals; Colloids; Deficiency Diseases; Diet; Female; Goiter; Hyperplasia; Iodine; Male; Organ Size;

1967
Morphological changes in mice thyroid induced by iodine deficiency.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1980, Volume: 32, Issue:3

    Topics: Animals; Female; Hyperplasia; Iodine; Male; Mice; Microscopy, Electron; Sex Factors; Thyroid Gland

1980
Vascularization and iodide transport down regulation in rat goitre.
    Acta endocrinologica, 1984, Volume: 105, Issue:1

    Topics: Animals; Biological Transport; Cell Membrane Permeability; Electrophoresis, Polyacrylamide Gel; Goit

1984
Morphological and functional changes during thyroid hyperplasia and involution in C3H Mice: evidence for folliculoneogenesis during involution.
    Endocrinology, 1983, Volume: 112, Issue:4

    Topics: Animals; Female; Hyperplasia; Iodine; Mice; Mice, Inbred C3H; Propylthiouracil; Thyroid Gland; Time

1983
Shedding of dense cell fragments into the follicular lumen early in involution of the hyperplastic thyroid gland.
    Laboratory investigation; a journal of technical methods and pathology, 1982, Volume: 47, Issue:1

    Topics: Animals; Cell Membrane; Diet; Endocytosis; Epithelium; Hyperplasia; Iodine; Male; Microvilli; Rats;

1982
Acute effects of iodine on the stimulated rat thyroid.
    Endocrinology, 1982, Volume: 111, Issue:5

    Topics: Animals; Hyperplasia; Iodine; Male; Microscopy, Electron, Scanning; Potassium Iodide; Rats; Rats, In

1982
Hyperplastic goitre in newborn foals in Western Canada.
    The Canadian veterinary journal = La revue veterinaire canadienne, 1981, Volume: 22, Issue:2

    Topics: Animals; Animals, Newborn; Goiter; Horse Diseases; Horses; Hyperplasia; Iodine; Thyroid Gland

1981
Correlated functional and morphometric study of thyroid hyperplasia induced by iodine deficiency.
    Endocrinology, 1981, Volume: 108, Issue:6

    Topics: Animals; Autoradiography; Epithelium; Female; Hyperplasia; Iodine; Male; Mice; Monoiodotyrosine; Org

1981
Morphometry of nuclear pore complexes in thyroid cells during hyperplasia and involution.
    Molecular and cellular endocrinology, 1981, Volume: 23, Issue:2

    Topics: Animals; Female; Hyperplasia; Iodine; Mice; Mice, Inbred C3H; Nuclear Envelope; Thyroid Gland

1981
Effects of selenium deficiency on thyroid necrosis, fibrosis and proliferation: a possible role in myxoedematous cretinism.
    European journal of endocrinology, 1995, Volume: 133, Issue:1

    Topics: Animals; Cell Division; Epithelium; Female; Fibrosis; Free Radicals; Goiter; Hydrogen Peroxide; Hype

1995
[Iodine deficiency induces thyroid cancer in rats and mice].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1994, Volume: 16, Issue:5

    Topics: Adenocarcinoma, Follicular; Animals; Carcinoma, Papillary; Deficiency Diseases; Female; Hyperplasia;

1994
Iodine-induced hypothyroidism: a clinical and histological study of 28 patients.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2

    Topics: Adult; Aged; Colloids; Epithelium; Female; Humans; Hyperplasia; Hypothyroidism; Immunohistochemistry

1993
Mechanism of thiazopyr-induced effects on thyroid hormone homeostasis in male Sprague-Dawley rats.
    Toxicology and applied pharmacology, 1997, Volume: 142, Issue:1

    Topics: Adenoma; Animals; Bile; Diet; Dose-Response Relationship, Drug; Enzyme Induction; Glucuronosyltransf

1997
Thyroid-stimulating hormone promotes growth of thyroid carcinomas in transgenic mice with targeted expression of the ret/PTC1 oncogene.
    Laboratory investigation; a journal of technical methods and pathology, 1997, Volume: 76, Issue:3

    Topics: Animals; Cattle; Drosophila Proteins; Female; Humans; Hyperplasia; Iodine; Male; Mice; Mice, Inbred

1997
Clinical and histologic evaluation of polyiodinated iodine with and without hypertonic saline/dextrose in the rabbit ear vein model.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1997, Volume: 23, Issue:8

    Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Drug Combinations; Ear, External; Endothelium, Vas

1997
CT imaging of intrathoracic lymph nodes in dogs with bronchoscopically administered iodinated nanoparticles.
    Academic radiology, 1999, Volume: 6, Issue:1

    Topics: Administration, Topical; Animals; Benzoates; Bronchography; Bronchoscopy; Contrast Media; Dogs; Hype

1999
Dramatic synergism between excess soybean intake and iodine deficiency on the development of rat thyroid hyperplasia.
    Carcinogenesis, 2000, Volume: 21, Issue:4

    Topics: Animals; Body Weight; Endoplasmic Reticulum, Rough; Female; Glycine max; Hyperplasia; Iodine; Micros

2000
Large amount of vitamin A has no major effects on thyroidal hormone synthesis in two-stage rat thyroid carcinogenesis model using N-bis(2-hydroxypropyl)nitrosamine and thiourea.
    The Journal of toxicological sciences, 2000, Volume: 25, Issue:2

    Topics: Adenoma; Animals; Body Weight; Bromodeoxyuridine; Carcinogens; Drug Synergism; Hyperplasia; Iodine;

2000
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.
    Carcinogenesis, 2001, Volume: 22, Issue:4

    Topics: Adenoma; Animals; Body Weight; Carcinogens; Carcinoma; Dose-Response Relationship, Drug; Female; Hyp

2001
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation.
    Japanese journal of cancer research : Gann, 2001, Volume: 92, Issue:4

    Topics: Animals; Cell Division; Dose-Response Relationship, Drug; Drug Synergism; Female; Glycine max; Hyper

2001
Studies of the tumorigenic effect of two goitrogens.
    Cancer, 1977, Volume: 40, Issue:5

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Diet; Glycolysis; Hyperplasia; Iodine; Liver Neoplasms;

1977
The epizootiology and pathogenesis of thyroid hyperplasia in coho salmon (Oncorhynchus kisutch) in Lake Ontario.
    Cancer research, 1976, Volume: 36, Issue:12

    Topics: Animals; Canada; Fish Diseases; Goiter; Hyperplasia; Iodine; Pituitary Gland; Salmon; Seasons; Thyro

1976
Effects of prolonged ethylene thiourea ingestion on the thyroid of the rat.
    Food and cosmetics toxicology, 1975, Volume: 13, Issue:5

    Topics: Animals; Blood Cell Count; Body Weight; Carcinogens; Female; Hemoglobinometry; Hyperplasia; Iodine;

1975
The effect of prolonged kale feeding on the thyroid glands of sheep.
    Journal of comparative pathology, 1976, Volume: 86, Issue:2

    Topics: Animal Feed; Animals; Blood Proteins; Female; Goiter; Hyperplasia; Hypertrophy; Iodine; Organ Size;

1976
Increase in estrogen receptor levels in MNU-induced thyroid tumors in LE rats.
    Carcinogenesis, 1992, Volume: 13, Issue:8

    Topics: Adenoma; Animals; Carcinoma; Estrogens; Female; Hyperplasia; Iodine; Male; Methylnitrosourea; Organ

1992
Stillbirth/perinatal weak calf syndrome: preliminary pathological, microbiological and biochemical findings.
    The Veterinary record, 1992, Mar-21, Volume: 130, Issue:12

    Topics: Animals; Animals, Newborn; Bacteria; Birth Weight; Brain; Cattle; Cattle Diseases; Female; Fetal Dea

1992
Negative effect of iodide on the survival of newly divided epithelial cells in chronically stimulated rat thyroid.
    Cell and tissue kinetics, 1986, Volume: 19, Issue:4

    Topics: Animals; Cell Division; Diet; Epithelium; Goiter; Hyperplasia; Iodine; Male; Propylthiouracil; Rats;

1986
Down regulation of hypertrophied follicular cell volume in thyroid hyperplastic gland.
    Histology and histopathology, 1989, Volume: 4, Issue:2

    Topics: Animals; Down-Regulation; Hyperplasia; Iodides; Iodine; Iodine Radioisotopes; Male; Microscopy, Elec

1989
Hypertrophy and hyperplasia during goitre growth and involution in rats--separate bioeffects of TSH and iodine.
    Acta endocrinologica, 1987, Volume: 116, Issue:4

    Topics: Animals; DNA; Female; Goiter; Hyperplasia; Hypertrophy; Iodine; Male; Organ Size; Potassium Chloride

1987
Cell kinetics of thyroid epithelial cells during hyperplastic goitre involution.
    The Journal of endocrinology, 1987, Volume: 114, Issue:3

    Topics: Animals; Cell Division; Epithelium; Hyperplasia; Iodine; Male; Microscopy, Electron; Organ Size; Rat

1987
Increased follicular heterogeneity in experimental colloid goiter produced by refeeding iodine excess after thyroid hyperplasia.
    Endocrinology, 1986, Volume: 118, Issue:2

    Topics: Animals; Cytoplasm; Endoplasmic Reticulum; Epithelium; Female; Goiter; Hyperplasia; Iodine; Mice; Mi

1986
Morphological and functional changes during thyroid hyperplasia and involution in C3H mice: effects of iodine and 3,5,3'-triiodothyronine during involution.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Animals; Diet; Female; Hyperplasia; Iodine; Mice; Mice, Inbred C3H; Thyroid Gland; Thyroxine; Triiod

1985
Production of a chronic arthritis with ovalbumin. Its retention in the rabbit knee joint.
    Annals of the rheumatic diseases, 1971, Volume: 30, Issue:3

    Topics: Animals; Arthritis; Female; Freund's Adjuvant; gamma-Globulins; Hindlimb; Hyperplasia; Immunization;

1971
Effects of short-term administration of ethylenethiourea upon thyroid function of the rat.
    Bulletin of environmental contamination and toxicology, 1972, Volume: 7, Issue:1

    Topics: Animals; Body Weight; Feeding Behavior; Hyperplasia; Imidazoles; Iodine; Iodine Radioisotopes; Male;

1972
Simultaneous Graves' disease and Cushing's syndrome with unusually low levels of plasma cortisol.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Basal Metabolism; Blood Pro

1968
Biological significance of a peculiar pattern of hormone release from iodine deficient rat goitres.
    Nature, 1968, Dec-28, Volume: 220, Issue:5174

    Topics: Animals; Deficiency Diseases; Feedback; Goiter; Hyperplasia; Iodine; Iodine Isotopes; Iodoproteins;

1968
[Therapy of diffuse dyshormonal hyperplasia of the breasts].
    Voprosy onkologii, 1973, Volume: 19, Issue:11

    Topics: Adenofibroma; Adenoma; Adult; Androgens; Breast Neoplasms; Female; Humans; Hyperplasia; Hypnotics an

1973
[Thyroid gland in acromegaly].
    Actualites endocrinologiques, 1973, Volume: 13, Issue:0

    Topics: Acromegaly; Adenoma; Adult; Female; Humans; Hyperplasia; Hyperthyroidism; Iodine; Iodine Radioisotop

1973
Effects of pharmacological doses of iodide on the hyperplastic rat thyroid gland. Roles of intrathyroidal iodide, thyrotropin and thyroglobulin in the Wolff-Chaikoff phenomenon.
    Endocrinology, 1974, Volume: 95, Issue:2

    Topics: Animals; Centrifugation, Zonal; Diet; Hyperplasia; Iodides; Iodine; Iodine Radioisotopes; Propylthio

1974
Peroxidase and NADPH-cytochrome C reductase activity during thyroid hyperplasia and involution.
    Endocrinology, 1974, Volume: 95, Issue:2

    Topics: Animals; Cell Count; Cytochrome Reductases; DNA; Enzyme Induction; Hyperplasia; Iodine; Kinetics; Ma

1974
Trypanosoma cruzi: thyroid hyperplasia, hyperthyroidism and variance in thyroid function in mice.
    Experimental parasitology, 1970, Volume: 27, Issue:1

    Topics: Animals; Chagas Disease; Hyperplasia; Hyperthyroidism; Iodine; Iodine Radioisotopes; Mice; Thyroid F

1970
Rat breast structure in altered iodine metabolism.
    Archives of pathology, 1972, Volume: 94, Issue:4

    Topics: Animals; Deficiency Diseases; Diet; Disease Models, Animal; Estradiol; Hyperplasia; In Vitro Techniq

1972
Evidence for relative iodine deficiency during puberty.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Deficiency Diseases; Female; Humans; Hyperplasia; Iodine

1972
The effect of bovine thyroid stimulating hormone and human chorionic somato-mammotropin on the uptake of 131-I by human hyperplastic thyroid gland in organ culture.
    British journal of experimental pathology, 1971, Volume: 52, Issue:3

    Topics: Adult; Culture Techniques; Female; Humans; Hyperplasia; Hyperthyroidism; Iodine; Iodine Isotopes; Ma

1971
The fine structure of experimentally induced hyperplastic and colloid goiter in the hamster.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:4

    Topics: Animals; Colloids; Cricetinae; Disease Models, Animal; Goiter; Hyperplasia; Iodine; Male; Microscopy

1969
Effect of iodine and thyroxine on the thyroid in thiouracil-treated rats.
    Acta Societatis Medicorum Upsaliensis, 1969, Volume: 74, Issue:3-4

    Topics: Angiography; Animals; Contrast Media; Depression, Chemical; Drug Synergism; Hyperplasia; Iodine; Mal

1969
Changes in DNA and weight of thyroid glands during hyperplasia and involution.
    Endocrinology, 1970, Volume: 86, Issue:2

    Topics: Animals; Diet; DNA; Hyperplasia; Iodine; Male; Mice; Organ Size; Polyploidy; Rats; Thiouracil; Thyro

1970
Organ culture of pathological human thyroid gland tissue.
    British journal of experimental pathology, 1968, Volume: 49, Issue:5

    Topics: Colloids; Culture Media; Culture Techniques; DNA; Glucose; Goiter; Humans; Hyperplasia; Iodine; Iodi

1968
Defective deiodinase activity and abnormal thyroidal iodoproteins.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:9

    Topics: Autoradiography; Centrifugation, Density Gradient; Diiodotyrosine; Goiter; Humans; Hyperplasia; Hypo

1969