Page last updated: 2024-10-18

iodine and Heart Failure

iodine has been researched along with Heart Failure in 46 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Background Although most individuals can adapt to a large iodine load and remain euthyroid, hypothyroidism can develop after iodine exposure."8.31Iodine-Induced Hypothyroidism and Long-Term Risks of Incident Heart Failure. ( Bashir, MT; Currier, JW; Ebrahimi, R; Guo, R; Inoue, K; Lee, ML; Leung, AM; Neverova, NV, 2023)
"To evaluate the relationship between myocardial extracellular volume (ECV) fraction measured using dual-energy computed tomography with late iodine enhancement (LIE-DECT) and risk of heart failure (HF) in patients without coronary artery disease (CAD), and to evaluate the relationship between ECV and left ventricular structure and function."8.02Myocardial extracellular volume fraction quantitation using cardiac dual-energy CT with late iodine enhancement in patients with heart failure without coronary artery disease: A single-center prospective study. ( Hu, CH; Huang, S; Jiang, JS; Qi, RX; Ruan, XW; Shao, J; Zhang, Q, 2021)
"Iodine-induced thyrotoxicosis, which raises several diagnostic and therapeutical challenges, is often overlooked."7.83Iodine-induced hyperthyroidism as combination of different etiologies: an overlooked entity in the elderly. ( Cascio, C; Foppiani, L; Lo Pinto, G, 2016)
"Background Although most individuals can adapt to a large iodine load and remain euthyroid, hypothyroidism can develop after iodine exposure."4.31Iodine-Induced Hypothyroidism and Long-Term Risks of Incident Heart Failure. ( Bashir, MT; Currier, JW; Ebrahimi, R; Guo, R; Inoue, K; Lee, ML; Leung, AM; Neverova, NV, 2023)
"To measure the myocardial extracellular volume (ECV) in patients with heart failure with preserved ejection fraction (HFpEF) using dual-energy computed tomography with late iodine enhancement (LIE-DECT) and to evaluate the relationship between ECV and risk of HFpEF and cardiac structure and function."4.12Measurement of myocardial extracellular volume fraction in patients with heart failure with preserved ejection fraction using dual-energy computed tomography. ( Gong, SC; Huang, S; Jiang, JS; Qi, RX; Shao, J; Xiao, J; Zhang, Q; Zheng, KL, 2022)
"To evaluate the relationship between myocardial extracellular volume (ECV) fraction measured using dual-energy computed tomography with late iodine enhancement (LIE-DECT) and risk of heart failure (HF) in patients without coronary artery disease (CAD), and to evaluate the relationship between ECV and left ventricular structure and function."4.02Myocardial extracellular volume fraction quantitation using cardiac dual-energy CT with late iodine enhancement in patients with heart failure without coronary artery disease: A single-center prospective study. ( Hu, CH; Huang, S; Jiang, JS; Qi, RX; Ruan, XW; Shao, J; Zhang, Q, 2021)
"Heart failure (HF) is a growing public health issue; its risk factors include inappropriate dietary intake of microelements such as iodine, selenium, zinc and iron, which may lead to thyroid dysfunction."3.91Heart failure, micronutrient profile, and its connection with thyroid dysfunction and nutritional status. ( Barbosa, F; Lima, LF; Navarro, AM; Simões, MV, 2019)
"Iodine-induced thyrotoxicosis, which raises several diagnostic and therapeutical challenges, is often overlooked."3.83Iodine-induced hyperthyroidism as combination of different etiologies: an overlooked entity in the elderly. ( Cascio, C; Foppiani, L; Lo Pinto, G, 2016)
" Patients treated for congestive heart failure with a combination of digoxin and diuretics demonstrated a higher concentration of sodium and chloride in their sweat fluid when compared to age-matched controls."3.67Influence of digoxin and diuretic therapy on sweat fluid composition. ( Aladjem, M; Benzon, L; Mor, A, 1985)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199037 (80.43)18.7374
1990's1 (2.17)18.2507
2000's0 (0.00)29.6817
2010's4 (8.70)24.3611
2020's4 (8.70)2.80

Authors

AuthorsStudies
Qi, RX2
Jiang, JS2
Shao, J2
Zhang, Q2
Zheng, KL1
Xiao, J1
Huang, S2
Gong, SC1
Inoue, K1
Guo, R1
Lee, ML1
Neverova, NV1
Ebrahimi, R1
Currier, JW1
Bashir, MT1
Leung, AM1
Ruan, XW1
Hu, CH1
Lima, LF1
Barbosa, F1
Simões, MV1
Navarro, AM1
Foppiani, L1
Cascio, C1
Lo Pinto, G1
Stacul, F1
van der Molen, AJ1
Reimer, P1
Webb, JA1
Thomsen, HS1
Morcos, SK1
Almén, T1
Aspelin, P1
Bellin, MF1
Clement, O1
Heinz-Peer, G1
CLOSUIT, M1
SERBER, W1
ISARD, HJ1
BERGELSON, VD1
SILVER, S1
CHAPMAN, EM1
ORTIZ, S1
COLQUE, CM1
PERINETTI, H1
BLUMGART, HL6
FREEDBERG, AS6
KURLAND, GS5
JAFFE, HL2
ROSENFELD, MH1
POBIRS, FW1
STUPPY, LJ1
BLANCO-SOLER ROS, C1
DE LA HOZ FABRA, J1
URIBARRI MURILLO, G1
HARTIGAN, JD1
FITZPATRICK, JE1
TSFASMAN, AZ1
BILLOW, BW1
FEINSTEIN, I1
ARONS, I1
GARNES, A1
MARKS, N1
WHITEMAN, NC1
AMPLATZ, K1
MARVIN, JF1
LOKEN, MK1
MILLER, WD1
EWING, WF1
STEEN, LH1
BRUNE, DF1
CHAILLET, JL1
SCHWARZ, F1
FRIEDELL, MT1
MAKELA, TE1
HAKKILA, RL1
HAKKILA, J1
MANARESI, A1
SALTER, WT1
CHAMOVITZ, DL1
Jacobi, CA1
Reichert, V1
Schmitz-Rixen, T1
Benker, G1
Preiss, H1
Kreuzer, H1
Reinwein, D1
Sadhukhan, B1
Gupta, JC1
Chowdhury, P1
Mukherjee, SR1
Ramsay, I1
Richardson, PJ1
Marsden, P1
McKerron, CG1
Beliaeva, AP1
Aronson, D1
Nitzan, Y1
Petcherski, S1
Bravo, E1
Habib, M1
Burkhoff, D1
Abraham, WT1
Schulz, R1
Gerke, C1
Stein, S1
Specht, MB1
Hirche, TO1
HAUGEN, HN1
AUDIER, M1
SERRADIMIGNI, A1
FRANCOIS, G1
LIAN, C1
REYNOLDS, T1
Mor, A1
Benzon, L1
Aladjem, M1
Smilari, L2
Licitra, G2
Zappia, A1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Diagnostic Value of TOF-18F-FDG-PET/CT in Patients With Suspected Pancreatic Cancer[NCT03914950]174 participants (Actual)Interventional2014-02-07Completed
Evaluation of the Safety & Performance of the AquaPass Medical Device, for Enhancing Fluid Transfer Through the Skin, by Increased Sweat Rate, on Healthy Volunteers and Chronic Edematous Patients[NCT04578353]25 participants (Actual)Interventional2020-01-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Lesion Size

Lesion or tumor size in cm in the pancreas measured in the diagnostic CT of the abdomen or upper abdomen. (NCT03914950)
Timeframe: 2 hours

Interventioncm (Mean)
Lesion Size in cm3.0

Participants With Increased Tracer Uptake Over the Pancreatic Lesion With and Without TOF

The number of participants with increased tracer uptake over the pancreatic lesion, i.e. the number of pancreatic lesions with increased tracer uptake with and without TOF. One pancreatic lesion per patient was measured. (NCT03914950)
Timeframe: 2 hours

InterventionParticipants (Count of Participants)
Participants With Increased Tracer Uptake With TOF116
Participants With Increased Tracer Uptake Without TOF101

SUVmax (Maximal Standard Uptake Value) Measurement 30 and 90 Min p.i. (Post Injection)

Quantitative measurement of regional tracer uptake by SUVmax in the TOF-PET/CT and standard PET/CT images over the FDG-accumulating lesions in the pancreas 30 and 90min p.i. The histopathological findings (malignant or benign) were assigned to the corresponding SUVmax values of the pancreatic lesions for the calculation of AUC values in ROC analysis. Then AUC values with and without TOF were compared with the DeLong-test to analyze if there is a significant difference in characterization of pancreatic lesions with TOF. (NCT03914950)
Timeframe: 2 hours

InterventionSUVmax (Number)
SUVmax TOF 30min p.i.0.77
SUVmax Without TOF 30min p.i.0.78
SUVmax TOF 90min p.i.0.81
SUVmax Without TOF 90min p.i.0.8

Reviews

2 reviews available for iodine and Heart Failure

ArticleYear
Contrast induced nephropathy: updated ESUR Contrast Media Safety Committee guidelines.
    European radiology, 2011, Volume: 21, Issue:12

    Topics: Contrast Media; Coronary Angiography; Europe; Female; Fluid Therapy; Gadolinium; Glomerular Filtrati

2011
[Nocturnal dyspnea].
    MMW Fortschritte der Medizin, 2018, Volume: 160, Issue:6

    Topics: Diagnosis, Differential; Dyspnea; Heart Failure; Humans; Male; Middle Aged; Polysomnography; Sleep A

2018

Trials

1 trial available for iodine and Heart Failure

ArticleYear
Enhancing Sweat Rate Using a Novel Device for the Treatment of Congestion in Heart Failure.
    Circulation. Heart failure, 2023, Volume: 16, Issue:1

    Topics: Heart Failure; Humans; Skin Temperature; Sweat; Sweating; Weight Loss

2023

Other Studies

43 other studies available for iodine and Heart Failure

ArticleYear
Measurement of myocardial extracellular volume fraction in patients with heart failure with preserved ejection fraction using dual-energy computed tomography.
    European radiology, 2022, Volume: 32, Issue:6

    Topics: Cicatrix; Heart Failure; Humans; Iodine; Myocardium; Predictive Value of Tests; Stroke Volume; Tomog

2022
Iodine-Induced Hypothyroidism and Long-Term Risks of Incident Heart Failure.
    Journal of the American Heart Association, 2023, 10-17, Volume: 12, Issue:20

    Topics: Adolescent; Adult; Aged; Cohort Studies; Female; Heart Failure; Humans; Hypothyroidism; Iodine; Male

2023
Myocardial extracellular volume fraction quantitation using cardiac dual-energy CT with late iodine enhancement in patients with heart failure without coronary artery disease: A single-center prospective study.
    European journal of radiology, 2021, Volume: 140

    Topics: Coronary Artery Disease; Heart Failure; Humans; Iodine; Myocardium; Predictive Value of Tests; Prosp

2021
Heart failure, micronutrient profile, and its connection with thyroid dysfunction and nutritional status.
    Clinical nutrition (Edinburgh, Scotland), 2019, Volume: 38, Issue:2

    Topics: Adult; Aged; Cross-Sectional Studies; Deficiency Diseases; Female; Heart Failure; Humans; Hypothyroi

2019
Iodine-induced hyperthyroidism as combination of different etiologies: an overlooked entity in the elderly.
    Aging clinical and experimental research, 2016, Volume: 28, Issue:5

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Failure; Humans; H

2016
[A case of carcinoma treated with radioiodine 131, complicated by pulmonary tuberculosis and congestive heart failure].
    Journal belge de radiologie, 1952, Volume: 35, Issue:2

    Topics: Heart Failure; Iodides; Iodine; Iodine Radioisotopes; Neoplasms; Radioactivity; Thyroid Gland; Thyro

1952
Radioiodine treatment of euthyroid patients with angina and congestive heart failure.
    The Journal of the Albert Einstein Medical Center, Philadelphia, 1953, Volume: 1, Issue:2

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioisotopes

1953
The diagnosis of thyrocardiac disease.
    American practitioner and digest of treatment, 1953, Volume: 4, Issue:9

    Topics: Heart Failure; Humans; Hyperthyroidism; Iodine; Iodine Radioisotopes; Radioisotopes

1953
[Internal irradiation of the normal thyroid for relief of chronic cardiac insufficiency].
    Archivos medicos de Cuba, 1954, Volume: 5, Issue:1

    Topics: Brachytherapy; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Thyroid Gland

1954
AN EXPERIENCE with I131 in cardiac disease; a preliminary report from the Isotope Committee of the New Britain General Hospital.
    Connecticut state medical journal, 1954, Volume: 18, Issue:5

    Topics: Heart Diseases; Heart Failure; Hospitals, General; Humans; Iodine; Iodine Radioisotopes; Isotopes; R

1954
[Congestive cardiac insufficiency associated with syphilitic aortic insufficiency, hyperthyroidism and nephrotic syndrome; I131, penicillin and ACTH therapy].
    Medicina, 1954, Volume: 14, Issue:2

    Topics: Adrenocorticotropic Hormone; Aortic Valve; Bicuspid Aortic Valve Disease; Glomerulonephritis; Heart

1954
Treatment of incapacitated euthyroid cardiac patients with radioactive iodine: summary of results in treatment of 1,070 patients with angina pectoris or congestive failure.
    Journal of the American Medical Association, 1955, Jan-01, Volume: 157, Issue:1

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioisotopes

1955
The treatment of incapacitated euthyroid cardiac patients with radioactive iodine; summary of results in treatment of 879 patients with angina pectoris or congestive failure in 46 clinics.
    Transactions of the Association of American Physicians, 1954, Volume: 67

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioisotopes

1954
Radioiodine treatment of euthyroid cardiac disease; four years of experience with two hundred thirty-one patients.
    Journal of the American Medical Association, 1955, Oct-01, Volume: 159, Issue:5

    Topics: Angina Pectoris; Heart Diseases; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioisotopes

1955
Severe euthyroid cardiac disease; technique for treatment with radioiodine.
    California medicine, 1955, Volume: 83, Issue:6

    Topics: Heart; Heart Diseases; Heart Failure; Humans; Hypothyroidism; Iodine; Iodine Radioisotopes; Thyrotox

1955
[Treatment of severe cardiac insufficiency with radioiodine].
    Revista clinica espanola, 1956, Jan-15, Volume: 60, Issue:1

    Topics: Heart Failure; Humans; Iodine; Iodine Radioisotopes

1956
Radioactive iodine (I131) in refractory heart disease: report of eight cases.
    The Nebraska state medical journal, 1957, Volume: 42, Issue:3

    Topics: Angina Pectoris; Heart; Heart Diseases; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Thyroid

1957
[Some peculiarities of radioactive iodine metabolism in circulatory insufficiency].
    Klinicheskaia meditsina, 1957, Volume: 35, Issue:4

    Topics: Heart Failure; Iodine

1957
Radioactive iodine treatment of angina pectoris and congestive heart failure.
    Circulation, 1957, Volume: 16, Issue:1

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes

1957
Radioactive iodine treatment of euthyroid patients with angina pectoris or congestive heart failure.
    The Harlem Hospital bulletin, 1957, Volume: 10, Issue:2

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioactivity; Radioisotopes

1957
The methyl iodide test in left to right shunts. Technical considerations.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1961, Volume: 85

    Topics: Heart Failure; Humans; Hydrocarbons, Iodinated; Iodine; Iodine Radioisotopes

1961
Selected problems of treatment in congestive heart failure.
    The Journal of the Oklahoma State Medical Association, 1960, Volume: 53

    Topics: Heart Failure; Humans; Iodine; Iodine Radioisotopes; Mitral Valve

1960
Use of radioactive iodine in the treatment of euthyroid patients with congestive failure.
    The Journal of the Indiana State Medical Association, 1962, Volume: 55

    Topics: Heart Failure; Humans; Iodine; Iodine Radioisotopes

1962
[Treatment of heart patients with antithyroids or iodine 131].
    Nederlands tijdschrift voor geneeskunde, 1963, Mar-30, Volume: 107

    Topics: Angina Pectoris; Antithyroid Agents; Heart Failure; Humans; Iodine; Iodine Isotopes

1963
RADIOACTIVE IODINE AND SURGERY OF THE THYROID.
    Journal of the American Geriatrics Society, 1964, Volume: 12

    Topics: Diagnosis, Differential; Geriatrics; Goiter; Heart Failure; Hyperthyroidism; Iodine; Iodine Isotopes

1964
Absorption of I 131-oleic acid in congestive heart failure.
    Acta medica Scandinavica, 1960, Jun-03, Volume: 167

    Topics: Heart Failure; Humans; Iodine; Oleic Acid; Oleic Acids; Radioisotopes

1960
[Treatment with radioactive iodine of angina pectoris and cardiac decompensation].
    Minerva nucleare, 1959, Volume: 3

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Radioisotopes

1959
Therapeutics and toxicology.
    Annual review of medicine, 1950, Volume: 1

    Topics: Anemia; Anemia, Pernicious; Antacids; Anti-Bacterial Agents; Arthritis; Arthritis, Rheumatoid; Blood

1950
The treatment of euthyroid cardiac patients with intractable angina pectoris and congestive failure with radioactive iodine.
    The Journal of clinical endocrinology and metabolism, 1950, Volume: 10, Issue:10

    Topics: Angina Pectoris; Heart Failure; Humans; Iodine; Iodine Compounds; Radioisotopes

1950
The heart and the thyroid; with particular reference to I131 treatment of heart disease.
    Circulation, 1952, Volume: 6, Issue:2

    Topics: Angina Pectoris; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart; Heart Disease

1952
Hypothyroidism produced by radioactive iodine (I131) in the treatment of euthyroid patients with angina pectoris and congestive heart failure; early results in various types of cardiovascular diseases and associated pathologic states.
    Circulation, 1950, Volume: 1, Issue:5

    Topics: Angina Pectoris; Heart; Heart Failure; Humans; Hypothyroidism; Iodine; Iodine Radioisotopes; Thyroid

1950
[Chemical pleurodesis with iodized talcum in persistent therapy refractory bronchocutaneous fistula].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1994, Volume: 65, Issue:3

    Topics: Bronchial Fistula; Coronary Artery Bypass; Cutaneous Fistula; Drainage; Heart Failure; Heart Valve P

1994
[Electrocardiographic changes in hyperthyroidism. Studies of 542 patients].
    Zeitschrift fur Kardiologie, 1974, Volume: 63, Issue:9

    Topics: Adult; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Complexes, Premature; Elec

1974
Thyroid function in heart disease.
    Indian heart journal, 1973, Volume: 25, Issue:3

    Topics: Adult; Blood Proteins; Heart Diseases; Heart Failure; Humans; Iodine; Iodine Radioisotopes; Protein

1973
Thyroid "hot" nodules.
    Postgraduate medical journal, 1972, Volume: 48, Issue:564

    Topics: Adult; Aged; Atrial Fibrillation; Blood Proteins; Female; Goiter, Nodular; Heart Failure; Humans; Hy

1972
[Protein-bound and butanol-extracted serum iodine levels in patients with chronic cardiac insufficiency].
    Terapevticheskii arkhiv, 1971, Volume: 43, Issue:11

    Topics: Adult; Aged; Chronic Disease; Female; Heart Failure; Humans; Iodine; Male; Middle Aged; Protein Bind

1971
A study of sweat electrolyte excretion in a patient suffering from congestive heart failure.
    Scandinavian journal of clinical and laboratory investigation, 1957, Volume: 9, Issue:2

    Topics: Biological Transport; Electrolytes; Heart Failure; Humans; Potassium; Sodium; Sweat

1957
[STUDIES ON POTASSIUM METABOLISM IN CARDIAC INSUFFICIENCY].
    Marseille medical, 1963, Volume: 100

    Topics: Blood Chemical Analysis; Diet, Sodium-Restricted; Diuretics; Erythrocytes; Feces; Heart Failure; Hyp

1963
[Diaphoretic form of left ventricular insufficiency].
    La Presse medicale, 1951, Jun-02, Volume: 59, Issue:37

    Topics: Heart Failure; Heart Ventricles; Humans; Sweat

1951
Sweat sodium levels in congestive heart failure.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1952, Volume: 79, Issue:1

    Topics: Anions; Heart Failure; Humans; Ions; Sodium; Sodium, Dietary; Sweat

1952
Influence of digoxin and diuretic therapy on sweat fluid composition.
    Mineral and electrolyte metabolism, 1985, Volume: 11, Issue:3

    Topics: Aged; Chlorides; Digoxin; Diuretics; Drug Therapy, Combination; Heart Failure; Humans; Sodium; Sodiu

1985
[Problems of congestive insufficiency. 3. Electrolytes (Na+, K+) in thermal sweat and in urine of patients with congestive heart failure and of normal subjects].
    Archivio per le scienze mediche, 1966, Volume: 121, Issue:4

    Topics: Heart Failure; Humans; Potassium; Sodium; Sweat; Urine

1966
[Pathogenetic problems in congestive cardiac insufficiency. IV. The electrolytes (Na+, K+) in sweat induced by heat and in urine of normal subjects exposed to various stimuli (aldosterone, sodium chloride)].
    Archivio per le scienze mediche, 1966, Volume: 121, Issue:6

    Topics: Aldosterone; Electrolytes; Heart Failure; Humans; Potassium; Sodium; Sodium Chloride; Sweat

1966