Page last updated: 2024-10-18

iodine and Folic Acid Deficiency

iodine has been researched along with Folic Acid Deficiency in 18 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
" Folic acid taken in early pregnancy can prevent neural tube defects."3.81The epidemiology of global micronutrient deficiencies. ( Bailey, RL; Black, RE; West, KP, 2015)
" With adequate investment and political support, the chances of eliminating iodine deficiency as a problem in women of reproductive age and young children and of eliminating vitamin A deficiency as a problem in young children in the future are high."3.70Candidate noninfectious disease conditions. ( Alnwick, D, 1998)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's3 (16.67)18.2507
2000's6 (33.33)29.6817
2010's7 (38.89)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Harika, R1
Faber, M1
Samuel, F1
Kimiywe, J1
Mulugeta, A1
Eilander, A1
Rosenberg, IH1
Tulchinsky, TH1
Bailey, RL1
West, KP1
Black, RE2
Nikolov, A1
Li, YO1
Diosady, LL1
Wesley, AS1
Brent, RL1
Roman ViƱas, B1
Ribas Barba, L1
Ngo, J1
Gurinovic, M1
Novakovic, R1
Cavelaars, A1
de Groot, LC1
van't Veer, P1
Matthys, C1
Serra Majem, L1
Heaf, J1
Jakobsen, U1
Tvedegaard, E1
Kanstrup, IL1
Fogh-Andersen, N1
Grischke, EM1
Wepner, U1
Rosenquist, TH1
van Waes, JG1
Shaw, GM1
Finnell, R1
Brown, AS1
Susser, ES1
Butler, PD1
Richardson Andrews, R1
Kaufmann, CA1
Gorman, JM1
Worthington-Roberts, B1
Alnwick, D1
Chang, YO1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Scientific Foundations for Developing and Validating Food-based Dietary Guidelines and a Healthy Eating Index for Ethiopia[NCT03394963]500 participants (Actual)Observational2019-11-01Completed
Feasibility, Acceptability and Directional Signal Effect on Blood Folate Levels of Iodized Salt Fortified With Folic Acid: Clinical Study[NCT05935631]32 participants (Actual)Interventional2023-01-24Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for iodine and Folic Acid Deficiency

ArticleYear
Micronutrient Status and Dietary Intake of Iron, Vitamin A, Iodine, Folate and Zinc in Women of Reproductive Age and Pregnant Women in Ethiopia, Kenya, Nigeria and South Africa: A Systematic Review of Data from 2005 to 2015.
    Nutrients, 2017, Oct-05, Volume: 9, Issue:10

    Topics: Adolescent; Adult; Anemia, Iron-Deficiency; Ethiopia; Female; Folic Acid; Folic Acid Deficiency; Hum

2017
Projected prevalence of inadequate nutrient intakes in Europe.
    Annals of nutrition & metabolism, 2011, Volume: 59, Issue:2-4

    Topics: Adult; Aged; Diet Records; Energy Intake; Europe; Feeding Behavior; Female; Folic Acid; Folic Acid D

2011
[Nutrition during pregnancy--current aspects].
    MMW Fortschritte der Medizin, 2004, Mar-11, Volume: 146, Issue:11

    Topics: Adult; Anemia, Iron-Deficiency; Energy Intake; Fatty Acids, Unsaturated; Female; Folic Acid; Folic A

2004
Nutrient effects upon embryogenesis: folate, vitamin A and iodine.
    Nestle Nutrition workshop series. Paediatric programme, 2005, Volume: 55

    Topics: Embryonic Development; Female; Folic Acid; Folic Acid Deficiency; Humans; Iodine; Maternal Nutrition

2005
Neurobiological plausibility of prenatal nutritional deprivation as a risk factor for schizophrenia.
    The Journal of nervous and mental disease, 1996, Volume: 184, Issue:2

    Topics: Brain; Female; Folic Acid Deficiency; Humans; Infant, Newborn; Iodine; Maternal Exposure; Nutrition

1996
Micronutrients in pregnancy.
    The British journal of nutrition, 2001, Volume: 85 Suppl 2

    Topics: Anemia, Iron-Deficiency; Avitaminosis; Embryonic and Fetal Development; Female; Folic Acid Deficienc

2001

Other Studies

12 other studies available for iodine and Folic Acid Deficiency

ArticleYear
Summary on iodine folate and vitamin B12.
    Nestle Nutrition Institute workshop series, 2012, Volume: 70

    Topics: Cognition; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; Humans;

2012
The key role of government in addressing the pandemic of micronutrient deficiency conditions in Southeast Asia.
    Nutrients, 2015, Apr-08, Volume: 7, Issue:4

    Topics: Asia, Southeastern; Dietary Supplements; Folic Acid Deficiency; Food, Fortified; Humans; Iodine; Iro

2015
The epidemiology of global micronutrient deficiencies.
    Annals of nutrition & metabolism, 2015, Volume: 66 Suppl 2

    Topics: Child, Preschool; Dietary Supplements; Female; Folic Acid; Folic Acid Deficiency; Food, Fortified; H

2015
[The necessity of vitamin and mineral intake during pregnancy].
    Akusherstvo i ginekologiia, 2007, Volume: 46 Suppl 4

    Topics: beta Carotene; Female; Folic Acid Deficiency; Humans; Iodine; Micronutrients; Pregnancy; Pregnancy C

2007
Folic acid fortification through existing fortified foods: iodized salt and vitamin A-fortified sugar.
    Food and nutrition bulletin, 2011, Volume: 32, Issue:1

    Topics: Chemical Phenomena; Developing Countries; Dietary Sucrose; Feasibility Studies; Folic Acid; Folic Ac

2011
The role of the pediatrician in preventing congenital malformations.
    Pediatrics in review, 2011, Volume: 32, Issue:10

    Topics: Abnormalities, Drug-Induced; Congenital Abnormalities; Down Syndrome; Environmental Exposure; Female

2011
Dietary habits and nutritional status of renal transplant patients.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2004, Volume: 14, Issue:1

    Topics: Absorptiometry, Photon; Body Composition; Diet; Dietary Fats; Feeding Behavior; Female; Folic Acid D

2004
[Vitamin D, folic acid and cobalamin deficiency. Underestimated risk].
    MMW Fortschritte der Medizin, 2005, Oct-06, Volume: 147, Issue:40

    Topics: Accidental Falls; Aged; Aged, 80 and over; Dementia; Folic Acid Deficiency; Humans; Iodine; Nutritio

2005
The role of maternal nutrition in the prevention of birth defects.
    Journal of the American Dietetic Association, 1997, Volume: 97, Issue:10 Suppl 2

    Topics: Congenital Abnormalities; Congenital Hypothyroidism; Diet; Female; Folic Acid Deficiency; Humans; Io

1997
Candidate noninfectious disease conditions.
    Bulletin of the World Health Organization, 1998, Volume: 76 Suppl 2

    Topics: Anemia, Iron-Deficiency; Child; Child, Preschool; Deficiency Diseases; Dietary Supplements; Female;

1998
Food fortification in South Africa. Report of a Medical Research Council project group.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1978, May-13, Volume: 53, Issue:19

    Topics: Anemia, Hypochromic; Animals; Folic Acid Deficiency; Food, Fortified; Glycine max; Humans; Iodine; M

1978
Effect of iodinated casein on production of vitamin B 12 and folic acid deficiency in rats.
    The American journal of physiology, 1969, Volume: 216, Issue:1

    Topics: Amino Acids; Animals; Biological Transport, Active; Blood Proteins; Carbon Isotopes; Caseins; Diet;

1969