Page last updated: 2024-10-18

iodine and Delayed Effects, Prenatal Exposure

iodine has been researched along with Delayed Effects, Prenatal Exposure in 83 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Research Excerpts

ExcerptRelevanceReference
"Thyroid healthy pregnant women (n=1275: age range 18-40 years) at ≤12 weeks gestation will be randomly assigned to receive multivitamin supplements containing 150 µg iodine or non-iodine-containing multivitamin daily throughout pregnancy."9.27Role of iodine-containing multivitamins during pregnancy for children's brain function: protocol of an ongoing randomised controlled trial: the SWIDDICH study. ( Chmielewska, A; Domellöf, M; Eggertsen, R; Eriksson, J; Gutefeldt, K; Hulthen, L; Johansson, B; Malmgren, H; Manousou, S; Nystrom Filipsson, H; Tornhage, CJ, 2018)
"Iodine intake must be boosted during pregnancy to meet the demands for increased production and placental transfer of thyroid hormone essential for optimal foetal development."9.01Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions. ( Eastman, CJ; Li, M; Ma, G, 2019)
"It is well known that severe iodine deficiency during pregnancy may cause impaired brain development in the child, with effects on cognitive and motor function, hearing and speech."9.01The effect of iodine deficiency during pregnancy on child development. ( Bath, SC, 2019)
"Most Portuguese women are followed throughout pregnancy in community Family Health Units, where family physicians may choose to follow the National recommendation or other, concerning iodine sufficiency."7.96Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study. ( Correia-Neves, M; Costa, P; Goios, A; Lopes-Pereira, M; Palha, JA; Quialheiro, A; Roque, S; Santos, NC; Vilarinho, L, 2020)
" Dietary iodine and supplementation were measured through questionnaires twice during pregnancy."7.88Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study. ( Alvarez-Pedrerol, M; Basterrechea, M; Espada, M; González, L; Ibarluzea, J; Julvez, J; Llop, S; Lopez-Espinosa, MJ; Murcia, M; Rebagliato, M; Riaño, I; Tardón, A; Vioque, J, 2018)
"Frequencies of TSH ≥ 5 mU/L may be a more sensitive indicator for iodine status during pregnancy rather than in the general population."7.85The Impact of Iodine Status on the Recall Rate of the Screening Program for Congenital Hypothyroidism: Findings from Two National Studies in Iran. ( Abdollahi, Z; Azhang, N; Azizi, F; Delshad, H; Khalili, D; Mehran, L; Nazeri, P; Yarahmadi, S, 2017)
"We report the cases of 3 infants with congenital hypothyroidism detected with the use of our newborn screening program, with evidence supporting excess maternal iodine ingestion (12."7.78Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. ( Boston, BA; Braverman, LE; Connelly, KJ; LaFranchi, SH; Pearce, EN; Pino, S; Sesser, D; Snyder, D, 2012)
"Iodine deficiency and hypothyroidism may decrease the expression of ERK1/2 in the hippocampus of pups."7.76[Effect of iodine deficiency and hypothyroidism on the protein expressions of ERK1/2 in the hippocampus of rat pups]. ( Chen, J; Dong, J; Liu, W; Wang, Y; Wei, W, 2010)
"Iodine deficiency and hypothyroidism may decrease the protein expression of CaMK II."7.76[Effect of iodine deficiency and hypothyroidism on the protein expressions of CaMK II in the hippocampus of pups]. ( Chen, J; Dong, J; Liu, W; Wang, Y; Wei, W, 2010)
"Endemic cretinism is characterised by multiple neurological defects including deaf-mutism, diplegia, squint, and mental deficiency."6.77Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy. ( Buttfield, IH; Hetzel, BS; Pharoah, P, 2012)
"Thyroid healthy pregnant women (n=1275: age range 18-40 years) at ≤12 weeks gestation will be randomly assigned to receive multivitamin supplements containing 150 µg iodine or non-iodine-containing multivitamin daily throughout pregnancy."5.27Role of iodine-containing multivitamins during pregnancy for children's brain function: protocol of an ongoing randomised controlled trial: the SWIDDICH study. ( Chmielewska, A; Domellöf, M; Eggertsen, R; Eriksson, J; Gutefeldt, K; Hulthen, L; Johansson, B; Malmgren, H; Manousou, S; Nystrom Filipsson, H; Tornhage, CJ, 2018)
"Iodine intake must be boosted during pregnancy to meet the demands for increased production and placental transfer of thyroid hormone essential for optimal foetal development."5.01Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions. ( Eastman, CJ; Li, M; Ma, G, 2019)
"It is well known that severe iodine deficiency during pregnancy may cause impaired brain development in the child, with effects on cognitive and motor function, hearing and speech."5.01The effect of iodine deficiency during pregnancy on child development. ( Bath, SC, 2019)
"6180 mother-child pairs with measures of urinary iodine and creatinine concentrations in pregnancy and child IQ."5.01Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data. ( Bath, SC; de Rijke, YB; Dineva, M; Espada, M; Guxens, M; Ibarluzea, JM; Korevaar, TIM; Levie, D; Llop, S; Murcia, M; Peeters, RP; Rayman, MP; Sunyer, J; Tiemeier, H; van Herwaarden, AE, 2019)
" Intervention studies provide some support for deficiencies of energy, protein, Zn and iodine and for multiple micronutrient deficiencies, at least during pregnancy."4.95Nutrition, infection and stunting: the roles of deficiencies of individual nutrients and foods, and of inflammation, as determinants of reduced linear growth of children. ( Millward, DJ, 2017)
"Exposure to maternal hypothyroxinemia during pregnancy, which is characterized by low free T4 but normal thyroid-stimulating hormone (TSH) levels, can negatively affect the foetus."4.89Maternal hypothyroxinemia and effects on cognitive functioning in childhood: how and why? ( Ghassabian, A; Henrichs, J; Peeters, RP; Tiemeier, H, 2013)
"Cretinism, which is characterized by marked intellectual impairment and is associated with severe iodine deficiency, has been appreciated for many years."4.80Thyroid hormone and intellectual development: a clinician's view. ( Lazarus, JH, 1999)
"Both insufficient and excessive maternal iodine consumption can result in congenital hypothyroidism."4.02Unusual cause of congenital hypothyroidism in a term infant. ( Vlaardingerbroek, H, 2021)
"We investigated this using a mouse model of hypothyroidism, induced by administration of an iodine-deficient diet supplemented with propylthiouracil during gestation."3.96Maternal hypothyroidism in mice influences glucose metabolism in adult offspring. ( Bargi-Souza, P; de Bray, A; Guillou, A; Hodson, DJ; Kemkem, Y; Mollard, P; Nasteska, D; Peliciari-Garcia, RA; Schaeffer, M, 2020)
"Most Portuguese women are followed throughout pregnancy in community Family Health Units, where family physicians may choose to follow the National recommendation or other, concerning iodine sufficiency."3.96Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study. ( Correia-Neves, M; Costa, P; Goios, A; Lopes-Pereira, M; Palha, JA; Quialheiro, A; Roque, S; Santos, NC; Vilarinho, L, 2020)
" Dietary iodine and supplementation were measured through questionnaires twice during pregnancy."3.88Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study. ( Alvarez-Pedrerol, M; Basterrechea, M; Espada, M; González, L; Ibarluzea, J; Julvez, J; Llop, S; Lopez-Espinosa, MJ; Murcia, M; Rebagliato, M; Riaño, I; Tardón, A; Vioque, J, 2018)
"Frequencies of TSH ≥ 5 mU/L may be a more sensitive indicator for iodine status during pregnancy rather than in the general population."3.85The Impact of Iodine Status on the Recall Rate of the Screening Program for Congenital Hypothyroidism: Findings from Two National Studies in Iran. ( Abdollahi, Z; Azhang, N; Azizi, F; Delshad, H; Khalili, D; Mehran, L; Nazeri, P; Yarahmadi, S, 2017)
"The evidence regarding a potential link of low-to-moderate iodine deficiency, selenium status, and cadmium exposure during pregnancy with neurodevelopment is either contradicting or limited."3.83Impact of prenatal exposure to cadmium on cognitive development at preschool age and the importance of selenium and iodine. ( Bottai, M; Chalkiadaki, G; Chatzi, L; Fthenou, E; Georgiou, V; Kampouri, M; Kippler, M; Kogevinas, M; Koutra, K; Kyriklaki, A; Vafeiadi, M; Vahter, M; Vassilaki, M, 2016)
" This study investigated the effects on the intelligence quotient (IQ) of children born to mothers with different levels of iodine supplementation, with or without the administration of levothyroxine (LT4), prior to and during pregnancy."3.83Effects of Maternal Iodine Nutrition and Thyroid Status on Cognitive Development in Offspring: A Pilot Study. ( Alibrandi, A; Candia Longo, A; Giorgianni, G; Moleti, M; Sturniolo, G; Tortorella, G; Trimarchi, F; Vermiglio, F, 2016)
"Excessive iodine intake during pregnancy was associated with an increased rate of hyperthyrotropinaemia in neonates and their mothers, especially in male neonates."3.81Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water. ( Chen, W; Chu, Z; Dong, F; Sang, Z; Shen, J; Tan, L; Wei, W; Yao, Z; Zhang, G; Zhang, S; Zhang, W; Zhao, N, 2015)
"Excessive iodine exposure during the fetal and neonatal periods can lead to neonatal hypothyroidism."3.80Effect of iodine loading on the thyroid hormone level of newborns living in Kayseri province. ( Bastug, O; Daar, G; Gunes, T; Halis, H; Korkmaz, L; Korkut, S; Kurtoglu, S; Memur, S; Ozturk, MA, 2014)
"We report the cases of 3 infants with congenital hypothyroidism detected with the use of our newborn screening program, with evidence supporting excess maternal iodine ingestion (12."3.78Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion. ( Boston, BA; Braverman, LE; Connelly, KJ; LaFranchi, SH; Pearce, EN; Pino, S; Sesser, D; Snyder, D, 2012)
"After 12 weeks of treatment (before pregnancy), iodine concentrations in urine and thyroid tissue and circulating thyroxine of adult females correlated with iodine intake."3.78Effect of maternal excessive iodine intake on neurodevelopment and cognitive function in rat offspring. ( Fan, C; Li, J; Liu, Y; Mao, J; Shan, Z; Teng, W; Wang, H; Zhang, H; Zhang, L, 2012)
"Our results indicate a risk of postnatal hypothyroidism among lambs from pregnant and lactating ewes having a high iodine intake."3.78The impact of high iodine intake on thyroid function in ewes and lambs. ( Baňoch, T; Dušová, H; Konečný, R; Kroupová, V; Peksa, Z; Svoboda, M; Trávníček, J, 2012)
"An adequate intake of iodine during pregnancy is essential for the synthesis of maternal thyroid hormones needed to support normal fetal development."3.77The effect of maternal iodine status on infant outcomes in an iodine-deficient Indian population. ( Das, PK; Ferguson, EL; Gray, AR; Menon, KC; Pandav, CS; Saraf, A; Skeaff, SA; Thomson, CD; Zodpey, S, 2011)
"Iodine deficiency and hypothyroidism may decrease the expression of ERK1/2 in the hippocampus of pups."3.76[Effect of iodine deficiency and hypothyroidism on the protein expressions of ERK1/2 in the hippocampus of rat pups]. ( Chen, J; Dong, J; Liu, W; Wang, Y; Wei, W, 2010)
"Iodine deficiency and hypothyroidism may decrease the protein expression of CaMK II."3.76[Effect of iodine deficiency and hypothyroidism on the protein expressions of CaMK II in the hippocampus of pups]. ( Chen, J; Dong, J; Liu, W; Wang, Y; Wei, W, 2010)
" Conversely, neonatal rat hyperthyroidism, induced by daily injections of 3,5,3'-triiodothyronine (T3), accelerated the extension of microglial processes and increased the density of cortical microglial cell bodies above physiological levels during the first postnatal week of life."3.71Regulation of microglial development: a novel role for thyroid hormone. ( Colin, C; Gervais, A; Izembart, M; Lima, FR; Mallat, M; Neto, VM, 2001)
" More than 50% of the babies with transient hypothyroidism had been exposed to iodine; maternal transfer of antibodies had occurred in a third of them."3.70Neonatal transient hypothyroidism: aetiological study. Italian Collaborative Study on Transient Hypothyroidism. ( Bona, G; Chiumello, G; Rapa, A; Vigone, MC; Weber, G, 1998)
"Activity of enolase in young offspring of the first and second generation of mice with hyperiodine goiter was all lower than that in controls from the day of their birth to the 30th day after birth, and that at hippocampal tissues in young mice of the second generation was significantly lower than that of the first generation on the 14th day of age."3.70[Effects of excessive iodine on activity of enolase in hippocampus of developing mice]. ( Feng, Z; Sun, S; Yin, G; Zhao, J; Zhu, H, 2000)
"Endemic cretinism is characterised by multiple neurological defects including deaf-mutism, diplegia, squint, and mental deficiency."2.77Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy. ( Buttfield, IH; Hetzel, BS; Pharoah, P, 2012)
"Iodine is a micronutrient essential for thyroid hormone synthesis."1.40Iodine-induced hypothyroidism in full-term infants with congenital heart disease: more common than currently appreciated? ( Braverman, LE; Brown, RS; Leung, AM; Levine, B; Thaker, VV, 2014)
"One hundred and sixty-six cases of primary hypothyroidism, confirmed by formal thyroid function tests, were identified, of which 24 were later found to be transient."1.28Transient primary hypothyroidism in the newborn: experience of the Victorian Neonatal Thyroid Screening Programme. ( Coakley, JC; Connelly, JF; Francis, I; Gold, H; Mathur, K, 1989)

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19902 (2.41)18.7374
1990's9 (10.84)18.2507
2000's18 (21.69)29.6817
2010's48 (57.83)24.3611
2020's6 (7.23)2.80

Authors

AuthorsStudies
Engel, SM2
Villanger, GD2
Herring, A2
Nethery, RC2
Drover, SSM2
Zoeller, RT2
Meltzer, HM2
Zeiner, P2
Knudsen, GP2
Reichborn-Kjennerud, T2
Longnecker, MP2
Aase, H2
Hay, I1
Hynes, KL1
Burgess, JR1
Eastman, CJ1
Ma, G1
Li, M1
Kemkem, Y1
Nasteska, D1
de Bray, A1
Bargi-Souza, P1
Peliciari-Garcia, RA1
Guillou, A1
Mollard, P1
Hodson, DJ1
Schaeffer, M1
Boyages, SC1
van Welie, N1
Portela, M1
Dreyer, K1
Schoonmade, LJ1
van Wely, M1
Mol, BWJ1
van Trotsenburg, ASP1
Lambalk, CB1
Mijatovic, V1
Finken, MJJ1
Lopes-Pereira, M1
Roque, S1
Costa, P1
Quialheiro, A1
Santos, NC1
Goios, A1
Vilarinho, L1
Correia-Neves, M1
Palha, JA1
Vlaardingerbroek, H1
Mehran, L1
Yarahmadi, S1
Khalili, D1
Nazeri, P1
Delshad, H1
Abdollahi, Z1
Azhang, N1
Azizi, F1
Murcia, M3
Espada, M2
Julvez, J1
Llop, S2
Lopez-Espinosa, MJ1
Vioque, J2
Basterrechea, M2
Riaño, I1
González, L1
Alvarez-Pedrerol, M2
Tardón, A2
Ibarluzea, J1
Rebagliato, M2
Manousou, S1
Johansson, B1
Chmielewska, A1
Eriksson, J1
Gutefeldt, K1
Tornhage, CJ1
Eggertsen, R1
Malmgren, H1
Hulthen, L1
Domellöf, M1
Nystrom Filipsson, H1
Hamby, T1
Kunnel, N1
Dallas, JS1
Wilson, DP1
Bath, SC3
Levie, D1
Korevaar, TIM1
Dineva, M1
van Herwaarden, AE1
de Rijke, YB1
Ibarluzea, JM1
Sunyer, J1
Tiemeier, H3
Rayman, MP2
Guxens, M1
Peeters, RP2
Henrichs, J2
Ghassabian, A2
Stagnaro-Green, A1
Pearce, EN4
Steer, CD1
Golding, J1
Emmett, P1
Mitka, M1
Zimmermann, MB1
Leung, AM3
Brent, GA1
Kurtoglu, S1
Bastug, O1
Daar, G1
Halis, H1
Korkmaz, L1
Memur, S1
Korkut, S1
Gunes, T1
Ozturk, MA1
Graham-Evans, K1
Brown, N1
Wei, W5
Wang, Y8
Dong, J5
Min, H2
Song, B1
Shan, Z3
Teng, W4
Xi, Q3
Chen, J5
Thaker, VV1
Braverman, LE4
Brown, RS1
Levine, B1
Sadakata, H1
Shinozaki, H1
Higuchi, T1
Minegishi, T1
Chen, W1
Sang, Z1
Tan, L1
Zhang, S1
Dong, F1
Chu, Z1
Zhao, N1
Zhang, G1
Yao, Z1
Shen, J1
Zhang, W1
León, G1
Castilla, AM1
Iñiguez, C1
Fernández-Somoano, A1
Blarduni, E1
Foradada, CM1
Syed, S1
Caron, P1
Moleti, M1
Trimarchi, F1
Tortorella, G1
Candia Longo, A1
Giorgianni, G1
Sturniolo, G1
Alibrandi, A1
Vermiglio, F1
Sasaki, Y1
Kikuchi, A1
Murai, M1
Kanasugi, T1
Isurugi, C1
Oyama, R1
Sugiyama, T1
Kippler, M1
Bottai, M1
Georgiou, V1
Koutra, K1
Chalkiadaki, G1
Kampouri, M1
Kyriklaki, A1
Vafeiadi, M1
Fthenou, E1
Vassilaki, M1
Kogevinas, M1
Vahter, M1
Chatzi, L1
Chauvet, P1
Terral, D1
Colombier, M1
Mulliez, A1
Suarez, C1
Brunhes, A1
Gallot, D1
Millward, DJ1
van Wijk, N1
Rijntjes, E2
van de Heijning, BJ1
Dewailly, E1
Suhas, E1
Mou, Y1
Dallaire, R1
Chateau-Degat, L1
Chansin, R1
Oken, E1
Platek, D1
Mitchell, ML1
Lee, SL1
Swarts, HJ1
Anand-Ivell, R1
Teerds, KJ1
Berbel, P1
Mestre, JL1
Santamaría, A1
Palazón, I1
Franco, A1
Graells, M1
González-Torga, A1
de Escobar, GM1
Glinoer, D1
Rovet, J2
Zimmermann, M1
Liu, W2
Lynch, ML1
Huang, LS1
Cox, C1
Strain, JJ1
Myers, GJ1
Bonham, MP1
Shamlaye, CF1
Stokes-Riner, A1
Wallace, JM1
Duffy, EM1
Clarkson, TW1
Davidson, PW1
Babu, S1
Sinha, RA1
Mohan, V1
Rao, G1
Pal, A1
Pathak, A1
Singh, M1
Godbole, MM1
Belcari, F1
Placidi, G1
Guzzetta, A1
Tonacchera, M1
Ciampi, M1
Bartoli, A1
Scaramuzzo, RT1
Frumento, P1
Cioni, G1
Pinchera, A3
Boldrini, A1
Ghirri, P1
Menon, KC1
Skeaff, SA1
Thomson, CD1
Gray, AR1
Ferguson, EL1
Zodpey, S1
Saraf, A1
Das, PK1
Pandav, CS1
Gilbert, ME1
Chen, Z1
Koibuchi, N1
Pharoah, P1
Buttfield, IH1
Hetzel, BS1
He, X1
Schuller, KE1
Roussilhes, A1
Jahreis, KA1
Connelly, KJ1
Boston, BA1
Sesser, D1
Snyder, D1
Pino, S1
LaFranchi, SH1
Suárez-Rodríguez, M1
Azcona-San Julián, C1
Alzina de Aguilar, V1
Konikowska, K1
Regulska-Ilow, B1
Rózańska, D1
Yu, F1
Xu, H1
Zhang, L1
Liu, Y1
Li, J1
Mao, J1
Fan, C1
Wang, H1
Zhang, H1
Dušová, H1
Trávníček, J1
Svoboda, M1
Baňoch, T1
Kroupová, V1
Peksa, Z1
Konečný, R1
Kasahara, T1
Narumi, S1
Okasora, K1
Takaya, R1
Tamai, H1
Hasegawa, T1
Trumpff, C1
De Schepper, J1
Tafforeau, J1
Van Oyen, H1
Vanderfaeillie, J1
Vandevijvere, S1
Choudhury, N1
Gorman, KS1
Kibirige, MS1
Hutchison, S1
Owen, CJ1
Delves, HT1
Ashdown, H1
Dumont, Y1
Ng, M1
Poole, S1
Boksa, P1
Luheshi, GN1
Tsintsadze, TG1
Gabrichidze, GO3
Lazrishvili, NI3
Metreveli, DS3
Mitagvariia, NP2
Rosenquist, TH1
van Waes, JG1
Shaw, GM1
Finnell, R1
Bekaia, GL1
Guo, HL1
Hou, XH1
Yang, XF1
Xu, J2
Bekaya, GL1
Mitagvariya, NP1
Guo, H1
Feng, J1
Yang, X1
Sullivan, KM1
Aghini Lombardi, FA1
Antonangeli, L2
Rago, T2
Chiovato, L2
Bargagna, S2
Bertucelli, B1
Ferretti, G2
Sbrana, B1
Marcheschi, M2
Brown, AS1
Susser, ES1
Butler, PD1
Richardson Andrews, R1
Kaufmann, CA1
Gorman, JM1
Martínez-Galán, JR1
Pedraza, P1
Santacana, M1
Escobar del Ray, F1
Morreale de Escobar, G1
Ruiz-Marcos, A1
Sunitha, Y1
Udaykumar, P1
Raghunath, M1
Weber, G1
Vigone, MC1
Rapa, A1
Bona, G1
Chiumello, G1
Gao, B1
Yin, G2
Lazarus, JH1
Lima, FR1
Gervais, A1
Colin, C1
Izembart, M1
Neto, VM1
Mallat, M1
Sun, S1
Feng, Z1
Zhao, J1
Zhu, H1
Vitti, P1
Aghini Lombardi, F1
Bertuccelli, B1
Pharoah, PO1
Connolly, KJ1
Coakley, JC1
Francis, I1
Gold, H1
Mathur, K1
Connelly, JF1
Clemens, PC1
Neumann, S1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Observational Study on the Impact of Iodine Supplementation on Maternal and Child's Thyroid Hormone Homeostasis and on the Child's Psychomotor Development, in the Portuguese Minho Region (IodineMinho)[NCT04288531]304 participants (Anticipated)Observational2020-01-10Recruiting
Study on Physiologic Requirement and Dietary Recommended Nutrient[NCT04419103]600 participants (Actual)Observational2019-07-01Completed
The Importance of Iodine During Pregnancy for Future Brain Function : a Randomized Placebo-controlled Trial. Swedish Iodine in Pregnancy and Development in Children (SWIDDICH) Study[NCT02378246]1,275 participants (Anticipated)Interventional2012-11-30Recruiting
Iodine Nutrition During Pregnancy and Related Neonatal Physical Development[NCT02586220]250 participants (Actual)Observational2015-08-31Completed
Study on the Compensatory Mechanism of Iodine Nutrition and the Optimal Intake Level of Lactating Women[NCT04492657]600 participants (Anticipated)Observational2020-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

15 reviews available for iodine and Delayed Effects, Prenatal Exposure

ArticleYear
Optimal Assessment and Quantification of Iodine Nutrition in Pregnancy and Lactation: Laboratory and Clinical Methods, Controversies and Future Directions.
    Nutrients, 2019, Oct-05, Volume: 11, Issue:10

    Topics: Age Factors; Child Development; Child, Preschool; Deficiency Diseases; Diet; Dietary Supplements; Fe

2019
Iodine contrast prior to or during pregnancy and neonatal thyroid function: a systematic review.
    European journal of endocrinology, 2021, Volume: 184, Issue:1

    Topics: Contrast Media; Female; Fertilization; Humans; Infant, Newborn; Infant, Newborn, Diseases; Iodine; M

2021
The effect of iodine deficiency during pregnancy on child development.
    The Proceedings of the Nutrition Society, 2019, Volume: 78, Issue:2

    Topics: Brain; Child; Child Development; Cognition; Dietary Supplements; Female; Humans; Iodine; Learning Di

2019
Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data.
    The Journal of clinical endocrinology and metabolism, 2019, 12-01, Volume: 104, Issue:12

    Topics: Adult; Child; Child, Preschool; Female; Humans; Infant; Intelligence; Iodine; Male; Maternal Exposur

2019
Maternal hypothyroxinemia and effects on cognitive functioning in childhood: how and why?
    Clinical endocrinology, 2013, Volume: 79, Issue:2

    Topics: Brain; Child; Cognition; Female; Humans; Iodine; Pregnancy; Pregnancy Complications; Prenatal Exposu

2013
Impact of mild thyroid hormone deficiency in pregnancy on cognitive function in children: lessons from the Generation R Study.
    Best practice & research. Clinical endocrinology & metabolism, 2014, Volume: 28, Issue:2

    Topics: Child, Preschool; Cognition; Cohort Studies; Executive Function; Female; Fetal Blood; Head; Humans;

2014
Maternal Hypothyroxinemia-Induced Neurodevelopmental Impairments in the Progeny.
    Molecular neurobiology, 2016, Volume: 53, Issue:3

    Topics: Brain; Cohort Studies; Endocrine Disruptors; Female; Forecasting; Humans; Infant, Newborn; Infant, P

2016
Iodine and the "near" eradication of cretinism.
    Pediatrics, 2015, Volume: 135, Issue:4

    Topics: Adolescent; Child; Child, Preschool; Congenital Hypothyroidism; Cross-Cultural Comparison; Cross-Sec

2015
Neurocognitive outcomes of children secondary to mild iodine deficiency in pregnant women.
    Annales d'endocrinologie, 2015, Volume: 76, Issue:3

    Topics: Adult; Child; Child, Preschool; Cognition; Cognition Disorders; Congenital Hypothyroidism; Female; H

2015
Nutrition, infection and stunting: the roles of deficiencies of individual nutrients and foods, and of inflammation, as determinants of reduced linear growth of children.
    Nutrition research reviews, 2017, Volume: 30, Issue:1

    Topics: Animals; Child; Child Development; Child Nutritional Physiological Phenomena; Dietary Proteins; Endo

2017
The influence of components of diet on the symptoms of ADHD in children.
    Roczniki Panstwowego Zakladu Higieny, 2012, Volume: 63, Issue:2

    Topics: Anemia, Iron-Deficiency; Attention Deficit Disorder with Hyperactivity; Causality; Child; Comorbidit

2012
Mild iodine deficiency in pregnancy in Europe and its consequences for cognitive and psychomotor development of children: a review.
    Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), 2013, Volume: 27, Issue:3

    Topics: Child; Cognition Disorders; Europe; Female; Humans; Iodine; Pregnancy; Prenatal Exposure Delayed Eff

2013
Nutrient effects upon embryogenesis: folate, vitamin A and iodine.
    Nestle Nutrition workshop series. Paediatric programme, 2005, Volume: 55

    Topics: Embryonic Development; Female; Folic Acid; Folic Acid Deficiency; Humans; Iodine; Maternal Nutrition

2005
Neurobiological plausibility of prenatal nutritional deprivation as a risk factor for schizophrenia.
    The Journal of nervous and mental disease, 1996, Volume: 184, Issue:2

    Topics: Brain; Female; Folic Acid Deficiency; Humans; Infant, Newborn; Iodine; Maternal Exposure; Nutrition

1996
Thyroid hormone and intellectual development: a clinician's view.
    Thyroid : official journal of the American Thyroid Association, 1999, Volume: 9, Issue:7

    Topics: Brain; Congenital Hypothyroidism; Developmental Disabilities; Female; Humans; Infant, Newborn; Intel

1999

Trials

3 trials available for iodine and Delayed Effects, Prenatal Exposure

ArticleYear
Role of iodine-containing multivitamins during pregnancy for children's brain function: protocol of an ongoing randomised controlled trial: the SWIDDICH study.
    BMJ open, 2018, 04-10, Volume: 8, Issue:4

    Topics: Adolescent; Adult; Brain; Dietary Supplements; Female; Humans; Infant, Newborn; Intelligence; Iodine

2018
Neurological damage to the fetus resulting from severe iodine deficiency during pregnancy.
    International journal of epidemiology, 2012, Volume: 41, Issue:3

    Topics: Congenital Hypothyroidism; Dietary Supplements; Female; Humans; Injections, Intramuscular; Iodine; I

2012
Effects of maternal iodine supplementation during pregnancy.
    Archives of disease in childhood, 1991, Volume: 66, Issue:1

    Topics: Adolescent; Child; Child Development; Double-Blind Method; Embryonic and Fetal Development; Female;

1991

Other Studies

65 other studies available for iodine and Delayed Effects, Prenatal Exposure

ArticleYear
Gestational thyroid hormone concentrations and risk of attention-deficit hyperactivity disorder in the Norwegian Mother, Father and Child Cohort Study.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Female; Humans; I

2023
Gestational thyroid hormone concentrations and risk of attention-deficit hyperactivity disorder in the Norwegian Mother, Father and Child Cohort Study.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Female; Humans; I

2023
Gestational thyroid hormone concentrations and risk of attention-deficit hyperactivity disorder in the Norwegian Mother, Father and Child Cohort Study.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Female; Humans; I

2023
Gestational thyroid hormone concentrations and risk of attention-deficit hyperactivity disorder in the Norwegian Mother, Father and Child Cohort Study.
    Paediatric and perinatal epidemiology, 2023, Volume: 37, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Case-Control Studies; Child; Female; Humans; I

2023
Mild-to-Moderate Gestational Iodine Deficiency Processing Disorder.
    Nutrients, 2019, Aug-22, Volume: 11, Issue:9

    Topics: Age Factors; Attention Deficit Disorder with Hyperactivity; Autism Spectrum Disorder; Biomarkers; Ch

2019
Maternal hypothyroidism in mice influences glucose metabolism in adult offspring.
    Diabetologia, 2020, Volume: 63, Issue:9

    Topics: Animals; Antithyroid Agents; Blood Glucose; Cell Proliferation; Diet, High-Fat; Disease Models, Anim

2020
Letter to the Editor: "Association of Maternal Iodine Status With Child IQ: A Meta-Analysis of Individual Participant Data".
    The Journal of clinical endocrinology and metabolism, 2020, 09-01, Volume: 105, Issue:9

    Topics: Child; Female; Humans; Intelligence; Iodine; Pregnancy; Prenatal Exposure Delayed Effects

2020
Impact of iodine supplementation during preconception, pregnancy and lactation on maternal thyroid homeostasis and offspring psychomotor development: protocol of the IodineMinho prospective study.
    BMC pregnancy and childbirth, 2020, Nov-13, Volume: 20, Issue:1

    Topics: Dietary Supplements; Female; Goiter; Humans; Infant; Infant, Newborn; Iodine; Male; Maternal Nutriti

2020
Unusual cause of congenital hypothyroidism in a term infant.
    BMJ case reports, 2021, Feb-19, Volume: 14, Issue:2

    Topics: Congenital Hypothyroidism; Female; Humans; Infant, Newborn; Iodine; Male; Netherlands; Pregnancy; Pr

2021
The Impact of Iodine Status on the Recall Rate of the Screening Program for Congenital Hypothyroidism: Findings from Two National Studies in Iran.
    Nutrients, 2017, Oct-30, Volume: 9, Issue:11

    Topics: Child; Cluster Analysis; Congenital Hypothyroidism; Female; Humans; Hypothyroidism; Incidence; Infan

2017
Iodine intake from supplements and diet during pregnancy and child cognitive and motor development: the INMA Mother and Child Cohort Study.
    Journal of epidemiology and community health, 2018, Volume: 72, Issue:3

    Topics: Adult; Child, Preschool; Cognition; Cognition Disorders; Creatinine; Cross-Sectional Studies; Develo

2018
Maternal iodine excess: an uncommon cause of acquired neonatal hypothyroidism.
    Journal of pediatric endocrinology & metabolism : JPEM, 2018, Sep-25, Volume: 31, Issue:9

    Topics: Congenital Hypothyroidism; Female; Humans; Infant, Newborn; Iodine; Neonatal Screening; Pregnancy; P

2018
Iodine and pregnancy: a call to action.
    Lancet (London, England), 2013, Jul-27, Volume: 382, Issue:9889

    Topics: Cognition Disorders; Developmental Disabilities; Female; Humans; Iodine; Pregnancy; Pregnancy Compli

2013
Effect of inadequate iodine status in UK pregnant women on cognitive outcomes in their children: results from the Avon Longitudinal Study of Parents and Children (ALSPAC).
    Lancet (London, England), 2013, Jul-27, Volume: 382, Issue:9889

    Topics: Adult; Child; Cognition Disorders; Creatinine; Developmental Disabilities; Dyslexia; Female; Humans;

2013
Even mild iodine deficiency during gestation may impair brain function in children.
    JAMA, 2013, Jun-19, Volume: 309, Issue:23

    Topics: Brain; Child; Child Development; Cognition Disorders; Cohort Studies; Deficiency Diseases; Dyslexia;

2013
Nutrition: Are mild maternal iodine deficiency and child IQ linked?
    Nature reviews. Endocrinology, 2013, Volume: 9, Issue:9

    Topics: Cognition Disorders; Developmental Disabilities; Female; Humans; Iodine; Learning Disabilities; Male

2013
Children of mothers with iodine deficiency during pregnancy are more likely to have lower verbal IQ and reading scores at 8-9 years of age.
    Evidence-based nursing, 2014, Volume: 17, Issue:3

    Topics: Cognition Disorders; Developmental Disabilities; Female; Humans; Iodine; Pregnancy; Pregnancy Compli

2014
Effect of iodine loading on the thyroid hormone level of newborns living in Kayseri province.
    American journal of perinatology, 2014, Volume: 31, Issue:12

    Topics: Anti-Infective Agents, Local; Female; Humans; Hypothyroidism; Infant, Newborn; Iodine; Male; Milk, H

2014
Maternal first-trimester iodine deficiency predicts poor cognitive outcome in English children.
    Archives of disease in childhood. Education and practice edition, 2014, Volume: 99, Issue:6

    Topics: Cognition Disorders; Developmental Disabilities; Female; Humans; Iodine; Pregnancy; Pregnancy Compli

2014
Hypothyroxinemia induced by maternal mild iodine deficiency impairs hippocampal myelinated growth in lactational rats.
    Environmental toxicology, 2015, Volume: 30, Issue:11

    Topics: Animals; Female; Hippocampus; Humans; Hypothyroidism; Iodides; Iodine; Lactation; Maternal Exposure;

2015
Iodine-induced hypothyroidism in full-term infants with congenital heart disease: more common than currently appreciated?
    The Journal of clinical endocrinology and metabolism, 2014, Volume: 99, Issue:10

    Topics: Anti-Infective Agents, Local; Bandages; Congenital Hypothyroidism; Contrast Media; Coronary Angiogra

2014
Case of radioactive iodine exposure during pregnancy.
    The journal of obstetrics and gynaecology research, 2014, Volume: 40, Issue:12

    Topics: Adult; Female; Fetal Development; Humans; Infant, Newborn; Iodine; Iodine Radioisotopes; Male; Pregn

2014
Neonatal thyroid function born to mothers living with long-term excessive iodine intake from drinking water.
    Clinical endocrinology, 2015, Volume: 83, Issue:3

    Topics: Adult; China; Cross-Sectional Studies; Drinking Water; Female; Fetal Blood; Geography; Humans; Infan

2015
Maternal thyroid dysfunction during gestation, preterm delivery, and birthweight. The Infancia y Medio Ambiente Cohort, Spain.
    Paediatric and perinatal epidemiology, 2015, Volume: 29, Issue:2

    Topics: Adult; Birth Weight; Female; Gestational Age; Humans; Hypothyroidism; Infant, Newborn; Iodine; Mothe

2015
Effects of Maternal Iodine Nutrition and Thyroid Status on Cognitive Development in Offspring: A Pilot Study.
    Thyroid : official journal of the American Thyroid Association, 2016, Volume: 26, Issue:2

    Topics: Adult; Child; Cognition; Dietary Supplements; Female; Humans; Intelligence Tests; Iodine; Maternal N

2016
Fetal goiter associated with preconception hysterosalpingography using an oil-soluble iodinated contrast medium.
    Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology, 2017, Volume: 49, Issue:2

    Topics: Adult; Contrast Media; Female; Goiter; Humans; Hysterosalpingography; Infant, Newborn; Infertility,

2017
Impact of prenatal exposure to cadmium on cognitive development at preschool age and the importance of selenium and iodine.
    European journal of epidemiology, 2016, Volume: 31, Issue:11

    Topics: Adult; Cadmium; Child Development; Child, Preschool; Cognition Disorders; Female; Greece; Humans; Io

2016
[Iodinated contrast in pregnant women and neonatal thyroid function].
    Gynecologie, obstetrique & fertilite, 2016, Volume: 44, Issue:12

    Topics: Congenital Hypothyroidism; Contrast Media; Female; Gestational Age; Humans; Infant, Newborn; Iodine;

2016
Perinatal and chronic hypothyroidism impair behavioural development in male and female rats.
    Experimental physiology, 2008, Volume: 93, Issue:11

    Topics: Age Factors; Animals; Behavior, Animal; Body Weight; Brain; Chronic Disease; Cognition; Disease Mode

2008
High fish consumption in French Polynesia and prenatal exposure to metals and nutrients.
    Asia Pacific journal of clinical nutrition, 2008, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Cross-Sectional Studies; Fatty Acids, Unsaturated; Female; Fetal Blood; Food Chai

2008
Neonatal thyroxine, maternal thyroid function, and child cognition.
    The Journal of clinical endocrinology and metabolism, 2009, Volume: 94, Issue:2

    Topics: Adult; Autoantibodies; Child Development; Child, Preschool; Cognition; Cohort Studies; Diet; Female;

2009
Prenatal induced chronic dietary hypothyroidism delays but does not block adult-type Leydig cell development.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 296, Issue:2

    Topics: Animals; Cell Differentiation; Cells, Cultured; Diet; Female; Fetal Nutrition Disorders; Hypothyroid

2009
Delayed neurobehavioral development in children born to pregnant women with mild hypothyroxinemia during the first month of gestation: the importance of early iodine supplementation.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:5

    Topics: Child Development; Deficiency Diseases; Dietary Supplements; Drug Administration Schedule; Female; G

2009
Gestational hypothyroxinemia and the beneficial effects of early dietary iodine fortification.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:5

    Topics: Child Development; Deficiency Diseases; Dietary Supplements; Drug Administration Schedule; Female; G

2009
Iodine Efficiency. Preface.
    Best practice & research. Clinical endocrinology & metabolism, 2010, Volume: 24, Issue:1

    Topics: Dietary Supplements; Female; Humans; Infant Nutrition Disorders; Infant, Newborn; Iodine; Maternal N

2010
[Effect of iodine deficiency and hypothyroidism on the protein expressions of CaMK II in the hippocampus of pups].
    Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:2

    Topics: Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Female; Hippocampus;

2010
[Effect of iodine deficiency and hypothyroidism on the protein expressions of ERK1/2 in the hippocampus of rat pups].
    Wei sheng yan jiu = Journal of hygiene research, 2010, Volume: 39, Issue:3

    Topics: Animals; Animals, Newborn; Female; Hippocampus; Hypothyroidism; Iodine; Mitogen-Activated Protein Ki

2010
Varying coefficient function models to explore interactions between maternal nutritional status and prenatal methylmercury toxicity in the Seychelles Child Development Nutrition Study.
    Environmental research, 2011, Volume: 111, Issue:1

    Topics: Arachidonic Acid; Child Development; Child Nutritional Physiological Phenomena; Child, Preschool; Ch

2011
Effect of hypothyroxinemia on thyroid hormone responsiveness and action during rat postnatal neocortical development.
    Experimental neurology, 2011, Volume: 228, Issue:1

    Topics: Animals; Animals, Newborn; Female; Hypothyroidism; Iodine; Neocortex; Pregnancy; Prenatal Exposure D

2011
Thyroid-stimulating hormone levels in the first days of life and perinatal factors associated with sub-optimal neuromotor outcome in pre-term infants.
    Journal of endocrinological investigation, 2011, Volume: 34, Issue:10

    Topics: Developmental Disabilities; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Infant, Newb

2011
The effect of maternal iodine status on infant outcomes in an iodine-deficient Indian population.
    Thyroid : official journal of the American Thyroid Association, 2011, Volume: 21, Issue:12

    Topics: Adult; Biomarkers; Body Height; Body Weight; Child Development; Diet; Female; Gestational Age; Human

2011
Developmental thyroid hormone disruption: prevalence, environmental contaminants and neurodevelopmental consequences.
    Neurotoxicology, 2012, Volume: 33, Issue:4

    Topics: Animals; Brain; Congenital Hypothyroidism; Endocrine Disruptors; Environmental Exposure; Environment

2012
Environmental perchlorate and thiocyanate exposures and infant serum thyroid function.
    Thyroid : official journal of the American Thyroid Association, 2012, Volume: 22, Issue:9

    Topics: Adult; Boston; Breast Feeding; Cross-Sectional Studies; Environmental Exposure; Female; Humans; Infa

2012
Congenital hypothyroidism caused by excess prenatal maternal iodine ingestion.
    The Journal of pediatrics, 2012, Volume: 161, Issue:4

    Topics: Congenital Hypothyroidism; Dietary Supplements; Diseases in Twins; Female; Humans; Infant, Newborn;

2012
Hypothyroxinemia during pregnancy: the effect on neurodevelopment in the child.
    International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, 2012, Volume: 30, Issue:6

    Topics: Child, Preschool; Cognition Disorders; Developmental Disabilities; Female; Humans; Hypothyroidism; I

2012
Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus.
    Environmental toxicology, 2014, Volume: 29, Issue:8

    Topics: Animals; Animals, Newborn; Dentate Gyrus; Doublecortin Protein; Down-Regulation; Female; Hippocampus

2014
Effect of maternal excessive iodine intake on neurodevelopment and cognitive function in rat offspring.
    BMC neuroscience, 2012, Oct-08, Volume: 13

    Topics: Age Factors; Animals; Animals, Newborn; Anti-Infective Agents, Local; Brain-Derived Neurotrophic Fac

2012
The impact of high iodine intake on thyroid function in ewes and lambs.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:5

    Topics: Animals; Animals, Newborn; Female; Hypothyroidism; Iodine; Lactation; Pregnancy; Prenatal Exposure D

2012
Delayed onset congenital hypothyroidism in a patient with DUOX2 mutations and maternal iodine excess.
    American journal of medical genetics. Part A, 2013, Volume: 161A, Issue:1

    Topics: Alleles; Child; Congenital Hypothyroidism; Dietary Supplements; Dual Oxidases; Female; Humans; Infan

2013
Subclinical prenatal iodine deficiency negatively affects infant development in Northern China.
    The Journal of nutrition, 2003, Volume: 133, Issue:10

    Topics: China; Cognition; Developmental Disabilities; Educational Status; Female; Fetal Blood; Humans; Infan

2003
Prevalence of maternal dietary iodine insufficiency in the north east of England: implications for the fetus.
    Archives of disease in childhood. Fetal and neonatal edition, 2004, Volume: 89, Issue:5

    Topics: Adolescent; Adult; Age Distribution; Congenital Hypothyroidism; Creatinine; Diet; England; Female; H

2004
The role of cytokines in mediating effects of prenatal infection on the fetus: implications for schizophrenia.
    Molecular psychiatry, 2006, Volume: 11, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Cytokines; Female; Fetal Blood; Inflammation; Interleukin-1; Inter

2006
[Altered ability to learn of rat offspring with iodine deficiency].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 2006, Volume: 52, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Congenital Hypothyroidism; Female; Iodine; Maze Learning; Potassiu

2006
[Local blood flow in the dorsal hippocampus and cerebellar cortex in progeny of iodine-deficient rats].
    Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 2006, Volume: 92, Issue:3

    Topics: Animals; Animals, Newborn; Cerebellar Cortex; Cerebrovascular Circulation; Cerebrovascular Disorders

2006
[Influences of excess iodine on thyroid hormone concentrations in cerebrum of filial mice and intervention of selenium].
    Wei sheng yan jiu = Journal of hygiene research, 2006, Volume: 35, Issue:2

    Topics: Animals; Animals, Newborn; Cerebrum; Female; Iodine; Male; Mice; Mice, Inbred BALB C; Pregnancy; Pre

2006
Local blood flow in the dorsal hippocampus and cerebellar cortex in the offspring of iodine-deficient rats.
    Neuroscience and behavioral physiology, 2007, Volume: 37, Issue:5

    Topics: Animal Feed; Animals; Cerebellar Cortex; Cerebrovascular Circulation; Female; Hippocampus; Iodine; M

2007
[Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice].
    Wei sheng yan jiu = Journal of hygiene research, 2007, Volume: 36, Issue:2

    Topics: Animals; Animals, Newborn; Cerebrum; Female; Iodine; Male; Mice; Mice, Inbred BALB C; Pregnancy; Pre

2007
The interaction of agricultural pesticides and marginal iodine nutrition status as a cause of autism spectrum disorders.
    Environmental health perspectives, 2008, Volume: 116, Issue:4

    Topics: Agriculture; Autistic Disorder; Environmental Exposure; Female; Humans; Hydrocarbons, Chlorinated; I

2008
Mild iodine deficiency during fetal/neonatal life and neuropsychological impairment in Tuscany.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:1

    Topics: Child; Cognition; Female; Goiter; Humans; Infant, Newborn; Iodine; Italy; Male; Nervous System Disea

1995
Early effects of iodine deficiency on radial glial cells of the hippocampus of the rat fetus. A model of neurological cretinism.
    The Journal of clinical investigation, 1997, Jun-01, Volume: 99, Issue:11

    Topics: Animals; Congenital Hypothyroidism; Diet; Embryonic and Fetal Development; Female; Hippocampus; Iodi

1997
Changes in blood-brain barrier nutrient transport in the offspring of iodine-deficient rats and their preventability.
    Neurochemical research, 1997, Volume: 22, Issue:7

    Topics: Animals; Blood-Brain Barrier; Female; Food, Fortified; Iodine; Lactation; Nutritional Status; Pregna

1997
Neonatal transient hypothyroidism: aetiological study. Italian Collaborative Study on Transient Hypothyroidism.
    Archives of disease in childhood. Fetal and neonatal edition, 1998, Volume: 79, Issue:1

    Topics: Adult; Anti-Infective Agents, Local; Antibodies; Contrast Media; Female; Humans; Hypothyroidism; Inf

1998
[Effects of high-dose iodine on brain development in mice].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 1997, Volume: 31, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Female; Humans; Infant, Newborn; Intellectual Disability; Iodine;

1997
Regulation of microglial development: a novel role for thyroid hormone.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Mar-15, Volume: 21, Issue:6

    Topics: Animals; Brain; Cell Count; Cell Division; Cell Survival; Cells, Cultured; Female; Hyperthyroidism;

2001
[Effects of excessive iodine on activity of enolase in hippocampus of developing mice].
    Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine], 2000, Volume: 34, Issue:1

    Topics: Animals; Brain; Female; Goiter; Hippocampus; Iodine; Male; Mice; Neurons; Phosphopyruvate Hydratase;

2000
Mild iodine deficiency in fetal/neonatal life and neuropsychological performances.
    Acta medica Austriaca, 1992, Volume: 19 Suppl 1

    Topics: Child; Congenital Hypothyroidism; Female; Humans; Iodine; Italy; Male; Neuropsychological Tests; Pre

1992
Transient primary hypothyroidism in the newborn: experience of the Victorian Neonatal Thyroid Screening Programme.
    Australian paediatric journal, 1989, Volume: 25, Issue:1

    Topics: Female; Humans; Hypothyroidism; Immunoglobulin G; Immunoglobulins, Thyroid-Stimulating; Infant, Newb

1989
Transient primary hypothyroidism in the neonate.
    Clinical pediatrics, 1989, Volume: 28, Issue:7

    Topics: Female; Humans; Hypothyroidism; Infant, Newborn; Iodine; Pregnancy; Prenatal Exposure Delayed Effect

1989