iodine has been researched along with Cell Transformation, Neoplastic in 17 studies
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In recent years important molecular pathways contributing to tumor progression and worse survival rates have been identified in iodine-refractory differentiated thyroid carcinoma (DTC) with the consequent development of molecular therapeutics to target these specific oncogenic pathways." | 8.91 | Targeting vascular endothelial growth factor (VEGF) pathway in iodine-refractory differentiated thyroid carcinoma (DTC): from bench to bedside. ( Abdel-Rahman, O, 2015) |
| "In iodine deficiency areas, activating mutations in the TSH receptor and Gs-alpha gene are found in the majority of toxic thyroid adenomas and in some toxic goiter nodules." | 8.80 | Pathogenesis of toxic thyroid adenomas and nodules: relevance of activating mutations in the TSH-receptor and Gs-alpha gene, the possible role of iodine deficiency and secondary and TSH-independent molecular mechanisms. ( Broecker, M; Derwahl, M; Manole, D; Sobke, A, 1998) |
| " In recent years important molecular pathways contributing to tumor progression and worse survival rates have been identified in iodine-refractory differentiated thyroid carcinoma (DTC) with the consequent development of molecular therapeutics to target these specific oncogenic pathways." | 4.91 | Targeting vascular endothelial growth factor (VEGF) pathway in iodine-refractory differentiated thyroid carcinoma (DTC): from bench to bedside. ( Abdel-Rahman, O, 2015) |
| "In iodine deficiency areas, activating mutations in the TSH receptor and Gs-alpha gene are found in the majority of toxic thyroid adenomas and in some toxic goiter nodules." | 4.80 | Pathogenesis of toxic thyroid adenomas and nodules: relevance of activating mutations in the TSH-receptor and Gs-alpha gene, the possible role of iodine deficiency and secondary and TSH-independent molecular mechanisms. ( Broecker, M; Derwahl, M; Manole, D; Sobke, A, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Kaushik, N | 1 |
| Kim, MJ | 1 |
| Kaushik, NK | 1 |
| Myung, JK | 1 |
| Choi, MY | 1 |
| Kang, JH | 1 |
| Cha, HJ | 1 |
| Kim, CS | 1 |
| Nam, SY | 1 |
| Lee, SJ | 1 |
| Marcon, J | 1 |
| Graser, A | 1 |
| Horst, D | 1 |
| Casuscelli, J | 1 |
| Spek, A | 1 |
| Stief, CG | 1 |
| Reiser, MF | 1 |
| Rübenthaler, J | 1 |
| Buchner, A | 1 |
| Staehler, M | 1 |
| Abdel-Rahman, O | 1 |
| Fuziwara, CS | 1 |
| Kimura, ET | 1 |
| Amagasa, T | 1 |
| Yamashiro, M | 1 |
| Uzawa, N | 1 |
| Buckwalter, TL | 1 |
| Venkateswaran, A | 1 |
| Lavender, M | 1 |
| La Perle, KM | 1 |
| Cho, JY | 1 |
| Robinson, ML | 1 |
| Jhiang, SM | 1 |
| Kessler, FK | 1 |
| Laskin, DL | 1 |
| Borzelleca, JF | 1 |
| Carchman, RA | 1 |
| Derwahl, M | 1 |
| Manole, D | 1 |
| Sobke, A | 1 |
| Broecker, M | 1 |
| Trapasso, F | 1 |
| Iuliano, R | 1 |
| Chiefari, E | 1 |
| Arturi, F | 1 |
| Stella, A | 1 |
| Filetti, S | 1 |
| Fusco, A | 1 |
| Russo, D | 1 |
| Rieber, M | 1 |
| Bacalao, J | 1 |
| Alonso, G | 1 |
| Voyles, BA | 1 |
| Moskowitz, M | 1 |
| Wynford-Thomas, D | 1 |
| Bond, JA | 1 |
| Wyllie, FS | 1 |
| Burns, JS | 1 |
| Williams, ED | 1 |
| Jones, T | 1 |
| Sheer, D | 1 |
| Lemoine, NR | 1 |
| Aaronson, SA | 1 |
| Poduslo, JF | 1 |
| Greenberg, CS | 1 |
| Glick, MC | 1 |
| Hynes, RO | 1 |
| Humphryes, KC | 1 |
| Critchley, DR | 1 |
| Matovinovic, J | 1 |
| Nishiyama, RH | 1 |
| Lalli, A | 1 |
| Poissant, G | 1 |
4 reviews available for iodine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Targeting vascular endothelial growth factor (VEGF) pathway in iodine-refractory differentiated thyroid carcinoma (DTC): from bench to bedside.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Carcinoma; Cell Transformation, Neoplastic; Clini | 2015 |
MicroRNAs in thyroid development, function and tumorigenesis.
Topics: Animals; Cell Differentiation; Cell Transformation, Neoplastic; DEAD-box RNA Helicases; Gene Express | 2017 |
Oral premalignant lesions: from a clinical perspective.
Topics: Adult; Cell Transformation, Neoplastic; Early Detection of Cancer; Female; Humans; Iodine; Keratosis | 2011 |
Pathogenesis of toxic thyroid adenomas and nodules: relevance of activating mutations in the TSH-receptor and Gs-alpha gene, the possible role of iodine deficiency and secondary and TSH-independent molecular mechanisms.
Topics: Adenoma; Animals; Cell Transformation, Neoplastic; Goiter, Nodular; Growth Substances; GTP-Binding P | 1998 |
13 other studies available for iodine and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation.
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Cell Transformation, Neoplastic; Disease Models, Animal; | 2019 |
Papillary vs clear cell renal cell carcinoma. Differentiation and grading by iodine concentration using DECT-correlation with microvascular density.
Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Papillary; Carcinoma, Renal Cell; Cell Transformation, Ne | 2020 |
The roles of phosphotyrosines-294, -404, and -451 in RET/PTC1-induced thyroid tumor formation.
Topics: Amino Acid Substitution; Animals; Antithyroid Agents; Carcinoma, Papillary; Cell Transformation, Neo | 2002 |
Assessment of somatogenotoxicity of povidone-iodine using two in vitro assays.
Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Iodine; Leukemia L5178; Mice; Mice | 1980 |
Iodide symporter gene expression in normal and transformed rat thyroid cells.
Topics: Animals; Blotting, Northern; Carrier Proteins; Cell Transformation, Neoplastic; Colforsin; Cyclic AM | 1999 |
Turnover of high-molecular-weight cell surface proteins during growth and expression of malignant transformation.
Topics: Animals; Autoradiography; Avian Sarcoma Viruses; Cell Line; Cell Membrane; Cell Transformation, Neop | 1975 |
Materials released into culture medium by normal and oncogenic virus-transformed mammalian cells.
Topics: Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Culture Media; Fucose; Gluc | 1976 |
Conditional immortalization of human thyroid epithelial cells: a tool for analysis of oncogene action.
Topics: Animals; Antigens, Viral, Tumor; Blotting, Northern; Cell Adhesion; Cell Differentiation; Cell Divis | 1990 |
Chemical induction of focus-forming virus from nonproducer cells transformed by murine sarcoma virus.
Topics: Amines; Animals; Antigens, Viral; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Clo | 1971 |
Proteins exposed on the surface of mammalian membranes.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Chlorofor | 1972 |
Characterization of the external proteins of hamster fibroblasts.
Topics: Animals; Autoradiography; Avian Sarcoma Viruses; Buffers; Carbon Radioisotopes; Cell Line; Cell Tran | 1974 |
Cell surface proteins of NIL1 hamster fibroblasts labeled by a galactose oxidase, tritiated borohydride method.
Topics: Alcohol Oxidoreductases; Animals; Borohydrides; Carbon Radioisotopes; Cell Count; Cell Line; Cell Me | 1974 |
"Benign metastasizing goiter" of Cohnheim: an experimental study with the transplantable thyroid tumor of the rat.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Transformation, Neoplastic; Diet; Femur; Goiter | 1971 |