Page last updated: 2024-10-18

iodine and Carcinoma, Medullary

iodine has been researched along with Carcinoma, Medullary in 7 studies

Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..

Carcinoma, Medullary: A carcinoma composed mainly of epithelial elements with little or no stroma. Medullary carcinomas of the breast constitute 5%-7% of all mammary carcinomas; medullary carcinomas of the thyroid comprise 3%-10% of all thyroid malignancies. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1141; Segen, Dictionary of Modern Medicine, 1992)

Research Excerpts

ExcerptRelevanceReference
"We conducted a phase II study to assess the efficacy of continuous dosing of sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)-avid, iodine-refractory well-differentiated thyroid carcinoma (WDTC) and medullary thyroid cancer (MTC) and to assess for early response per FDG-PET."9.14Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. ( Bauman, JE; Capell, PT; Carr, LL; Eaton, KD; Goulart, BH; Kell, EM; Mankoff, DA; Martins, RG, 2010)
"We conducted a phase II study to assess the efficacy of continuous dosing of sunitinib in patients with flurodeoxyglucose positron emission tomography (FDG-PET)-avid, iodine-refractory well-differentiated thyroid carcinoma (WDTC) and medullary thyroid cancer (MTC) and to assess for early response per FDG-PET."5.14Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation. ( Bauman, JE; Capell, PT; Carr, LL; Eaton, KD; Goulart, BH; Kell, EM; Mankoff, DA; Martins, RG, 2010)
"The prevalence and pathology pattern of iodine deficiency (ID) related disorders are influenced by the dietary iodine intake: low iodine leads to thyroid nodular enlargement, to an increase in the incidence of thyroid cancer, an increase in anaplastic carcinomas and to an alteration in the papillary to follicular neoplasia ratio."3.81Iodine deficiency and thyroid nodular pathology--epidemiological and cancer characteristics in different populations: Portugal and South Africa. ( Castelo Branco, M; Freitas, M; Kalk, WJ; Marques Carreira, I; Santos, JE, 2015)
"These data suggest that the potential malignancy of thyroid nodules is not only correlated to the diameter but to other parameters such as the biological difference of thyroid cancer that could be hypothesized in an iodine deficiency area."3.71[Prevalence and aggressiveness of thyroid carcinoma with diameter less than one centimetre in iodine deficiency areas]. ( Agosti, B; Cappelli, C; Cerudelli, B; Cumetti, D; Morassi, ML; Pelizzari, G; Tironi, A, 2002)
"We studied all thyroid cancers notified to the Danish Cancer Registry in the period 1973-1997, focusing on the four most frequent subtypes: papillary, follicular, anaplastic and medullary thyroid cancer."1.33Iodine intake and incidence of thyroid cancer in Denmark. ( Johansen, C; Knudsen, N; Perrild, H; Sehestedt, T, 2006)
"Papillary carcinoma was the predominant histologic type (26-70."1.32A prospective study of thyroid nodular disease in children and adolescents in western Poland from 1996 to 2000 and the incidence of thyroid carcinoma relative to iodine deficiency and the Chernobyl disaster. ( Breborowicz, D; Breborowicz, J; Harasymczuk, J; Korman, E; Niedziela, M; Rolski, M; Trejster, E; Warzywoda, M, 2004)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santos, JE1
Kalk, WJ1
Freitas, M1
Marques Carreira, I1
Castelo Branco, M1
Carr, LL1
Mankoff, DA1
Goulart, BH1
Eaton, KD1
Capell, PT1
Kell, EM1
Bauman, JE1
Martins, RG1
Niedziela, M1
Korman, E1
Breborowicz, D1
Trejster, E1
Harasymczuk, J1
Warzywoda, M1
Rolski, M1
Breborowicz, J1
Faggiano, A1
Coulot, J1
Bellon, N1
Talbot, M1
Caillou, B1
Ricard, M1
Bidart, JM1
Schlumberger, M1
Sehestedt, T1
Knudsen, N1
Perrild, H1
Johansen, C1
Rieu, M1
Lame, MC1
Richard, A1
Lissak, B1
Sambort, B1
Vuong-Ngoc, P1
Berrod, JL1
Fombeur, JP1
Cappelli, C1
Agosti, B1
Tironi, A1
Morassi, ML1
Pelizzari, G1
Cumetti, D1
Cerudelli, B1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Multicenter, Open-label, Phase II Study of the Optimal Scheme of Administration of Pazopanib in Thyroid Carcinoma[NCT01813136]Phase 2168 participants (Actual)Interventional2013-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for iodine and Carcinoma, Medullary

ArticleYear
Phase II study of daily sunitinib in FDG-PET-positive, iodine-refractory differentiated thyroid cancer and metastatic medullary carcinoma of the thyroid with functional imaging correlation.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2010, Nov-01, Volume: 16, Issue:21

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma; Carcinoma, Medullary; Cell Differentiation; Drug Admi

2010

Other Studies

6 other studies available for iodine and Carcinoma, Medullary

ArticleYear
Iodine deficiency and thyroid nodular pathology--epidemiological and cancer characteristics in different populations: Portugal and South Africa.
    BMC research notes, 2015, Jul-01, Volume: 8

    Topics: Adenocarcinoma, Follicular; Adolescent; Adult; Aged; Carcinoma; Carcinoma, Medullary; Carcinoma, Neu

2015
A prospective study of thyroid nodular disease in children and adolescents in western Poland from 1996 to 2000 and the incidence of thyroid carcinoma relative to iodine deficiency and the Chernobyl disaster.
    Pediatric blood & cancer, 2004, Volume: 42, Issue:1

    Topics: Adenocarcinoma, Follicular; Adolescent; Adult; Carcinoma, Medullary; Carcinoma, Papillary; Child; Fe

2004
Age-dependent variation of follicular size and expression of iodine transporters in human thyroid tissue.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:2

    Topics: Adolescent; Adult; Aging; Biological Transport; Carcinoma, Medullary; Carrier Proteins; Cell Divisio

2004
Iodine intake and incidence of thyroid cancer in Denmark.
    Clinical endocrinology, 2006, Volume: 65, Issue:2

    Topics: Adenocarcinoma, Follicular; Adenocarcinoma, Papillary; Adult; Aged; Carcinoma; Carcinoma, Medullary;

2006
Prevalence of sporadic medullary thyroid carcinoma: the importance of routine measurement of serum calcitonin in the diagnostic evaluation of thyroid nodules.
    Clinical endocrinology, 1995, Volume: 42, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Calcitonin; Carcinoma, Medullary; Car

1995
[Prevalence and aggressiveness of thyroid carcinoma with diameter less than one centimetre in iodine deficiency areas].
    Minerva endocrinologica, 2002, Volume: 27, Issue:2

    Topics: Adenocarcinoma, Follicular; Biopsy, Needle; Calcinosis; Carcinoma, Medullary; Carcinoma, Papillary;

2002