iodine has been researched along with Bacterial Infections, Gram-Positive in 2 studies
Iodine: A nonmetallic element of the halogen group that is represented by the atomic symbol I, atomic number 53, and atomic weight of 126.90. It is a nutritionally essential element, especially important in thyroid hormone synthesis. In solution, it has anti-infective properties and is used topically.
diiodine : Molecule comprising two covalently bonded iodine atoms with overall zero charge..
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Swenson, BR | 1 |
| Hedrick, TL | 1 |
| Metzger, R | 1 |
| Bonatti, H | 1 |
| Pruett, TL | 1 |
| Sawyer, RG | 1 |
| Peris, C | 1 |
| Díaz, JR | 1 |
| Segura, C | 1 |
| Martí, A | 1 |
| Fernández, N | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Residual Effect of Chlorhexidine 2% / Isopropyl Alcohol 70% Compared to Triclosan 1% / Isopropyl Alcohol 70%[NCT01762904] | Phase 3 | 135 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"135 units of measurement to test two antiseptics and two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol and 1% triclosan in 70% isopropyl alcohol, Deionized water redistilled and Scrub the skin without prior application of any substance was tested. We prepared four skin's areas of 25 cm2, two in each forearm. The solution remained on the skin for 60s, 3h and 24h.~Presence of allergy or any skin reaction at 24 hours after the antiseptic application." (NCT01762904)
Timeframe: 24 hours
| Intervention | participants (Median) |
|---|---|
| Whole Group of 135 Units of Measurement | 0 |
"135 units of measurement to test two controls. Principal unit of measurement: four determinations of bacterial counts in a subject for antiseptics and controls to test each of the application sites.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. Deionized water redistilled (Control 2: Control with scrub) and Scrub the skin without prior application of any substance (Control1: Control without scrub) was tested. Were prepared two skin's areas of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hrs
| Intervention | (CFU/cm2) (Median) | |||||
|---|---|---|---|---|---|---|
| Control 1: without scrub 0 h | Control 2: scrub with Deionized water redisti 0 h | Control 1: without scrub 3 h | Control 2: scrub with Deionized water redisti 3 h | Control 1: without scrub 24 h | Control 2: scrub with Deionized water redisti 24 h | |
| Whole Group of 135 Units of Measurement | 480 | 216 | 288 | 96 | 288 | 96 |
"135 determinations to evaluate residual effect of 2% chlorhexidine in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 2% chlorhexidine in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 24 | 48 | 24 |
"135 determinations to test 1% triclosan in 70% isopropyl alcohol.~All volunteers was provided with a neutral soap without antiseptics for use of two weeks. 1% triclosan in 70% isopropyl alcohol was tested. Were prepared the skin area of 25 cm2 randomly selected. The solution remained on the skin for 60s, 3h and 24h, everyone on different days.~Cultures was taken with a scrub-cup of 5 cm2 pressed over the skin, added a 3 mL of culture broth. The skin was scrub with a sterile rubber policeman for 1 minute and the procedure conducted once again. Both aliquots came together in a sterile tube, a sample of 50 microliters were spread in a plate containing a neutralizing agar and were incubated at 35°C for 24 h." (NCT01762904)
Timeframe: 24 hours
| Intervention | (CFU/cm2) (Median) | ||
|---|---|---|---|
| 0 h | 3 h | 24 h | |
| Whole Group of 135 Units of Measurement | 48 | 48 | 96 |
1 trial available for iodine and Bacterial Infections, Gram-Positive
| Article | Year |
|---|---|
Effects of preoperative skin preparation on postoperative wound infection rates: a prospective study of 3 skin preparation protocols.
Topics: 2-Propanol; Adult; Aged; Anti-Infective Agents, Local; Chlorhexidine; Female; Gram-Positive Bacteria | 2009 |
1 other study available for iodine and Bacterial Infections, Gram-Positive
| Article | Year |
|---|---|
Influence of pulsation rate on udder health and teat thickness changes in dairy ewes.
Topics: Animals; Cell Count; Dairying; Female; Gram-Positive Bacterial Infections; Iodine; Lactation; Mammar | 2003 |