iocarmate-meglumine and Severe-Acute-Respiratory-Syndrome

iocarmate-meglumine has been researched along with Severe-Acute-Respiratory-Syndrome* in 1 studies

Other Studies

1 other study(ies) available for iocarmate-meglumine and Severe-Acute-Respiratory-Syndrome

Article	Year
Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein. Clinical immunology (Orlando, Fla.), 2004, Volume: 113, Issue:2 To assess specific cytotoxic T lymphocytes (CTLs) against Severe acute respiratory syndrome (SARS)-coronavirus, a modified DimerX flow cytometry assay was performed with peripheral blood mononuclear cell (PBMC) from HLA-A2+ SARS-recovered donors at different time points post disease. CD8+DimerX-S1203+ CTLs were detected in the PBMC from these donors up to 3 months after recovery. The percentages of CD8+DimerX-S1203+ cells paralleled the numbers of interferon-gamma-positive spots in an ELISPOT assay using the same antigenic peptide. In conclusion, DimerX-based flow cytometry staining may prove to be a real-time method to screen for CTL directed at epitopes from a newly identified virus. Topics: Animals; Epitopes, T-Lymphocyte; Flow Cytometry; HLA-A2 Antigen; Humans; Immunoglobulins; Interferon-gamma; Iothalamic Acid; Meglumine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; T-Lymphocytes, Cytotoxic; Viral Fusion Proteins	2004

Article

Year

Detecting specific cytotoxic T lymphocytes against SARS-coronavirus with DimerX HLA-A2:Ig fusion protein.

Clinical immunology (Orlando, Fla.), 2004, Volume: 113, Issue:2

To assess specific cytotoxic T lymphocytes (CTLs) against Severe acute respiratory syndrome (SARS)-coronavirus, a modified DimerX flow cytometry assay was performed with peripheral blood mononuclear cell (PBMC) from HLA-A2+ SARS-recovered donors at different time points post disease. CD8+DimerX-S1203+ CTLs were detected in the PBMC from these donors up to 3 months after recovery. The percentages of CD8+DimerX-S1203+ cells paralleled the numbers of interferon-gamma-positive spots in an ELISPOT assay using the same antigenic peptide. In conclusion, DimerX-based flow cytometry staining may prove to be a real-time method to screen for CTL directed at epitopes from a newly identified virus.

Topics: Animals; Epitopes, T-Lymphocyte; Flow Cytometry; HLA-A2 Antigen; Humans; Immunoglobulins; Interferon-gamma; Iothalamic Acid; Meglumine; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; T-Lymphocytes, Cytotoxic; Viral Fusion Proteins

2004