iocarmate-meglumine and Epilepsy--Tonic-Clonic

Topics: Adult; Contrast Media; Epilepsy, Tonic-Clonic; Female; Humans; Iothalamic Acid; Male; Meglumine; Middle Aged; Radiculopathy; Radiography; Sorbitol; Spinal Nerve Roots

Lumbar myelographies were carried out with lopamidol and locarmat of identical concentrations of iodine in 2 groups of 20 patients each. In about one-third of the cases, clinical side effects and EEG changes were found after the examination without difference with the exception of one seizure and one state of confusion which occurred only after locarmat. Resorption of the contrast media was judged by CT examinations of the lumbar spine and the head. There was a more rapid decrease of lumbar contrast density in patients with a narrow lumbar sac which was accompanied by a more rapid intracranial accumulation of the contrast medium. This may be due to a more active transport of cerebrospinal fluid in this group of patients.

Topics: Adult; Aged; Brain; Contrast Media; Electroencephalography; Epilepsy, Tonic-Clonic; Evoked Potentials; Female; Humans; Intervertebral Disc Displacement; Iopamidol; Iothalamic Acid; Male; Meglumine; Middle Aged; Myelography; Sorbitol; Spinal Cord; Spinal Nerve Roots; Tomography, X-Ray Computed