inulicin and Hyperplasia

inulicin has been researched along with Hyperplasia* in 1 studies

Other Studies

1 other study(ies) available for inulicin and Hyperplasia

Article	Year
[Inulicin inhibits activation and expression of vascular remodeling enzymes induced by de-endothelium]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:2 To observe the effects of inulicin on the neointimal hyperplasia and expression of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) after balloon injury in rat aorta.. The intimal hyperplasia model was replicated by balloon injury. The histological changes in vascular wall were observed by HE staining. MMP-2 activation was tested by gelatin zymogram analysis; MMP-2 and TIMP-2 expression was detected by Western blot and immunohistochemistry analysis.. Neointimal hyperplasia induced by balloon injury was significantly inhibited by inulicin. The proteolytic activity and the expression of MMP-2 and ratio of MMP-2 and TIMP-2 were also returned to control level by inulicin after balloon injury.. Inulicin inhibits hyperplasia of neointima by modulating the balance of MMP-2 and TIMP-2. Topics: Animals; Endothelium, Vascular; Hyperplasia; Male; Matrix Metalloproteinase 2; Neointima; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tissue Inhibitor of Metalloproteinase-2	2008

Article

Year

[Inulicin inhibits activation and expression of vascular remodeling enzymes induced by de-endothelium].

Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2008, Volume: 24, Issue:2

To observe the effects of inulicin on the neointimal hyperplasia and expression of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinase-2 (TIMP-2) after balloon injury in rat aorta.. The intimal hyperplasia model was replicated by balloon injury. The histological changes in vascular wall were observed by HE staining. MMP-2 activation was tested by gelatin zymogram analysis; MMP-2 and TIMP-2 expression was detected by Western blot and immunohistochemistry analysis.. Neointimal hyperplasia induced by balloon injury was significantly inhibited by inulicin. The proteolytic activity and the expression of MMP-2 and ratio of MMP-2 and TIMP-2 were also returned to control level by inulicin after balloon injury.. Inulicin inhibits hyperplasia of neointima by modulating the balance of MMP-2 and TIMP-2.

Topics: Animals; Endothelium, Vascular; Hyperplasia; Male; Matrix Metalloproteinase 2; Neointima; Rats; Rats, Sprague-Dawley; Sesquiterpenes; Tissue Inhibitor of Metalloproteinase-2

2008