interleukin-8 has been researched along with Toothache* in 2 studies
1 review(s) available for interleukin-8 and Toothache
| Article | Year |
|---|---|
Update on the adaptive immune responses of the dental pulp.
Recent advances in immunology have disclosed the enormous complexity of the immune regulatory system. The dental pulp is equipped to mount adaptive immune responses to caries, which include at least antigen-presenting cells, lymphocytes, mast cells and their cytokines, and chemokines. The purpose of this review is to summarize our current understanding of the roles of these cellular and molecular components in the irreversibly inflamed pulp. The immunopathology of abscess formation and the mechanisms for painless pulpitis are also discussed. Topics: Animals; B-Lymphocytes; Chemokines; Cytokines; Dendritic Cells; Dental Caries; Dental Pulp; Humans; Immunity, Innate; Interleukin-8; Macrophages; Periapical Abscess; Pulpitis; T-Lymphocytes; Toothache | 2007 |
1 trial(s) available for interleukin-8 and Toothache
| Article | Year |
|---|---|
Effect of an intraosseous injection of depo-medrol on pulpal concentrations of PGE2 and IL-8 in untreated irreversible pulpitis.
The purpose of this prospective, randomized, double-blind study was to evaluate the pulpal concentrations of prostaglandin E2 (PGE2) and interleukin-8 (IL-8) in untreated teeth with irreversible pulpitis after the administration of an intraosseous injection of Depo-Medrol. Forty emergency patients with a clinical diagnosis of irreversible pulpitis experiencing moderate to severe pain participated. After receiving local anesthesia, patients randomly received, in a double-blind manner, an intraosseous injection of either 1 ml of Depo-Medrol (40 mg) (20 patients) or 1 ml of sterile saline placebo (control) (20 patients). No endodontic treatment was initiated. At 1 or 3 days after the intraosseous injection, the teeth were extracted and the pulpal tissue harvested. Prostaglandin E2 and interleukin-8 concentrations were determined by enzyme immunoassay. Results demonstrated a significantly (p < 0.05) lower concentration of prostaglandin E2 compared to the saline group at day 1. There were no significant (p > 0.05) differences between the two groups at day 3. The pulpal concentrations of prostaglandin E2 were reduced at 1 day after the intraosseous injection of Depo-Medrol. Topics: Adult; Anti-Inflammatory Agents; Bone and Bones; Chi-Square Distribution; Dental Pulp; Dinoprostone; Double-Blind Method; Female; Humans; Injections; Interleukin-8; Male; Methylprednisolone; Methylprednisolone Acetate; Pain Measurement; Prospective Studies; Pulpitis; Statistics, Nonparametric; Toothache | 2003 |