interleukin-8 and Dysmenorrhea

To determine whether interleukin-8 (IL-8) serum levels are correlated with pelvic pain in patients with ovarian endometriomas.. Prospective study.. Tertiary-care university hospital.. Interleukin-8 serum levels were prospectively analyzed in 51 patients (group A, asymptomatic patients or patients with mild dysmenorrhea; group B, severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists between IL-8 serum levels and pelvic pain.. Interleukin-8 serum levels determination.. Interleukin-8 serum levels and pelvic pain.. From 56 patients, five cases were ultimately excluded because the histologic diagnosis was not cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean (+/-SD) IL-8 serum levels in group A were 6.41 +/- 12.17 pg/mL and in group B were 6.52 +/- 8.73 pg/mL.. Pain symptoms in ovarian endometriosis is not correlated with IL-8 serum levels.

Topics: Adult; Biomarkers; Chronic Disease; Dysmenorrhea; Endometriosis; Female; Humans; Interleukin-8; Ovarian Cysts; Pelvic Pain; Prospective Studies