insulin-detemir and Drug-Overdose

insulin-detemir has been researched along with Drug-Overdose* in 2 studies

Other Studies

2 other study(ies) available for insulin-detemir and Drug-Overdose

Article	Year
Inadvertent iatrogenic insulin detemir 1000 units overdose in a hospitalised patient. BMJ case reports, 2019, Dec-29, Volume: 12, Issue:12 A 69-year-old woman with uncontrolled type 2 diabetes mellitus was admitted in the hospital for the management of urosepsis. Patient was overdosed with detemir insulin 1000 units inadvertently. Care provider was confused with volume and dose of the insulin by using insulin vial. Blood sugars were monitored closely every 30 min-1 hour for 24 hours. Patient was treated with dextrose 5% and 10% continuous infusion; and hydrocortisone 75 mg every 6 hours for 24 hours. The lowest blood sugar reached was 142 mg/dL (7.9 mmo/L). Patient did not develop hypoglycaemia. Proper safety measures and mandatory nurse education about administration of insulin were implemented to prevent future occurrences. Topics: Aged; Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Overdose; Female; Glucose; Health Personnel; Hospitalization; Humans; Hydrocortisone; Iatrogenic Disease; Infusions, Intravenous; Insulin Detemir; Sweetening Agents; Treatment Outcome; Urinary Tract Infections	2019
Problem based review: the patient who has taken an overdose of long-acting insulin analogue. Acute medicine, 2013, Volume: 12, Issue:3 Insulin overdose can cause harm due to hypoglycaemia, effects on electrolytes and acute hepatic injury. The established long-acting insulin analogue preparations (detemir and glargine) can present specific management problems because, in overdose, their effects are extremely prolonged, often lasting 48-96 hours. The primary treatment is continuous intravenous 10% or 20% glucose infusion with frequent capillary blood glucose monitoring. Surgical excision of the insulin injection site has been used successfully, even days after the overdose occurred. Once the effects of overdose have receded, diabetes treatment must be restarted with care, especially in patients with type 1 diabetes. Monitoring serum insulin concentration has been successfully used to predict when the effects of the overdose will cease. Topics: Adult; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Drug Overdose; Electrolytes; Glucose; Humans; Hypoglycemia; Infusions, Intravenous; Insulin Detemir; Insulin Glargine; Insulin, Long-Acting; Male; Sweetening Agents	2013

Article

Year

Inadvertent iatrogenic insulin detemir 1000 units overdose in a hospitalised patient.

BMJ case reports, 2019, Dec-29, Volume: 12, Issue:12

A 69-year-old woman with uncontrolled type 2 diabetes mellitus was admitted in the hospital for the management of urosepsis. Patient was overdosed with detemir insulin 1000 units inadvertently. Care provider was confused with volume and dose of the insulin by using insulin vial. Blood sugars were monitored closely every 30 min-1 hour for 24 hours. Patient was treated with dextrose 5% and 10% continuous infusion; and hydrocortisone 75 mg every 6 hours for 24 hours. The lowest blood sugar reached was 142 mg/dL (7.9 mmo/L). Patient did not develop hypoglycaemia. Proper safety measures and mandatory nurse education about administration of insulin were implemented to prevent future occurrences.

Topics: Aged; Anti-Inflammatory Agents; Blood Glucose; Diabetes Mellitus, Type 2; Drug Overdose; Female; Glucose; Health Personnel; Hospitalization; Humans; Hydrocortisone; Iatrogenic Disease; Infusions, Intravenous; Insulin Detemir; Sweetening Agents; Treatment Outcome; Urinary Tract Infections

2019

Problem based review: the patient who has taken an overdose of long-acting insulin analogue.

Acute medicine, 2013, Volume: 12, Issue:3

Insulin overdose can cause harm due to hypoglycaemia, effects on electrolytes and acute hepatic injury. The established long-acting insulin analogue preparations (detemir and glargine) can present specific management problems because, in overdose, their effects are extremely prolonged, often lasting 48-96 hours. The primary treatment is continuous intravenous 10% or 20% glucose infusion with frequent capillary blood glucose monitoring. Surgical excision of the insulin injection site has been used successfully, even days after the overdose occurred. Once the effects of overdose have receded, diabetes treatment must be restarted with care, especially in patients with type 1 diabetes. Monitoring serum insulin concentration has been successfully used to predict when the effects of the overdose will cease.

Topics: Adult; Blood Glucose Self-Monitoring; Diabetes Mellitus, Type 1; Drug Overdose; Electrolytes; Glucose; Humans; Hypoglycemia; Infusions, Intravenous; Insulin Detemir; Insulin Glargine; Insulin, Long-Acting; Male; Sweetening Agents

2013