insulin--isophane and Glycosuria

An 18-year-old female Bali mynah (Leucopsar rothschildi) was presented for polyphagia, weight loss, and incoordination. Diabetes mellitus was diagnosed based on the history and clinical findings, including persistent hyperglycemia with concurrent hypoinsulinemia and glucosuria. A treatment protocol was developed that led to improvement of clinical signs and management of hyperglycemia over several months. Because of the advanced age of the animal, difficulty in maintaining euglycemia, and the stress of handling and treatment, euthanasia was elected 167 days after initial presentation. At postmortem examination, no pancreatic lesions were detected histologically that would account for the diabetes mellitus. To our knowledge this is the first reported case of diabetes mellitus and clinical management of this condition in a passerine species.

Topics: Animals; Animals, Zoo; Bird Diseases; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Glycosuria; Injections, Intramuscular; Injections, Subcutaneous; Insulin; Insulin, Isophane; Starlings; Sulfachlorpyridazine

Topics: Adult; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glycosuria; Humans; Hypoglycemic Agents; Insulin, Isophane; Male; Middle Aged; Postprandial Period

Topics: Child; Diabetes Mellitus, Type 1; Enuresis; Glycosuria; Home Nursing; Humans; Hypoglycemia; Insulin; Insulin, Isophane; Patient Compliance; Self Medication

Topics: Animals; Antigens; Blood Glucose; Body Weight; Cattle; Cross Reactions; Diabetes Mellitus; Dogs; Electrophoresis; Fatty Acids, Nonesterified; Glucagon; Glycosuria; Immune Sera; Insulin; Insulin, Isophane; Insulin, Long-Acting; Iodine Radioisotopes; Pancreatectomy; Rabbits; Radioimmunoassay; Swine

Topics: Adolescent; Ambulatory Care; Child; Diabetes Mellitus, Type 1; Diet, Diabetic; Female; Glucose Oxidase; Glycosuria; Humans; Insulin; Insulin, Isophane; Insulin, Long-Acting; Male; Methods; Specimen Handling

Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Chlorpropamide; Diabetes Mellitus; Drug Synergism; Female; Glycosuria; Humans; Insulin; Insulin Antibodies; Insulin Resistance; Insulin, Isophane; Insulin, Long-Acting; Male; Middle Aged; Obesity; Phenformin; Tolbutamide

Topics: Diabetes Mellitus; Drug Therapy; Glycosuria; Humans; Insulin; Insulin, Isophane; Ketones; Ketosis; Necrobiosis Lipoidica; Steroids; Tolbutamide; Toxicology; Triamcinolone Acetonide; Urine

Topics: Blood Glucose; Diabetes Mellitus; Globins; Glycosuria; Humans; Insulin; Insulin, Isophane; Urine