inositol has been researched along with Uremia in 30 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
Excerpt | Relevance | Reference |
---|---|---|
"It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia." | 7.71 | Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002) |
"It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia." | 3.71 | Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002) |
"To determine whether so-called uraemic toxins exhibit direct toxic effects on Schwann cells, the latter were cultured in a monolayer with the addition of uraemic toxins." | 1.28 | Myoinositol inhibits proliferation of cultured Schwann cells: evidence for neurotoxicity of myoinositol. ( Maeda, K; Mitsuma, T; Niwa, T; Sobue, G, 1989) |
"Inositol was quantified by the internal standard method." | 1.27 | Measurement of inositol in uremic serum by selected ion monitoring. ( Inouye, M; Mio, T; Sumino, K, 1988) |
"In a series of patients with chronic renal failure managed conservatively, the rise in the plasma-myo-inositol (myoinositol) concentration has been found to be related to depression of sural-nerve conduction velocity." | 1.26 | Plasma-myoinositol concentrations in uraemic neuropathy. ( Reznek, RH; Salway, JG; Thomas, PK, 1977) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 24 (80.00) | 18.7374 |
1990's | 3 (10.00) | 18.2507 |
2000's | 2 (6.67) | 29.6817 |
2010's | 1 (3.33) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Ferrer, MD | 1 |
Ketteler, M | 1 |
Tur, F | 1 |
Tur, E | 1 |
Isern, B | 1 |
Salcedo, C | 1 |
Joubert, PH | 1 |
Behets, GJ | 1 |
Neven, E | 1 |
D'Haese, PC | 1 |
Perelló, J | 1 |
Rysz, J | 1 |
Bartnicki, P | 2 |
Błaszczak, R | 1 |
Kujawski, K | 1 |
Ciałkowska-Rysz, A | 1 |
Olszewski, R | 1 |
Markuszewski, L | 1 |
Fürst, P | 2 |
Alvestrand, A | 1 |
Bergström, J | 2 |
Savazzi, GM | 1 |
Buzio, C | 1 |
Migone, L | 1 |
Navarro, J | 1 |
Contreras, P | 1 |
Touraine, JL | 1 |
Freyria, AM | 1 |
Later, R | 1 |
Traeger, J | 1 |
Niwa, T | 4 |
Yamamoto, N | 1 |
Maeda, K | 3 |
Yamada, K | 2 |
Ohki, T | 2 |
Mori, M | 1 |
Dewald, L | 1 |
Sone, J | 1 |
Miyazaki, T | 1 |
Kajita, M | 1 |
Zbróg, Z | 1 |
Baj, Z | 1 |
Tchórzewski, H | 1 |
Luciak, M | 1 |
De Kimpe, J | 1 |
Cornelis, R | 1 |
Vanholder, R | 1 |
Soupart, A | 1 |
Silver, S | 1 |
Schroöeder, B | 1 |
Sterns, R | 1 |
Decaux, G | 1 |
Reznek, RH | 1 |
Salway, JG | 1 |
Thomas, PK | 1 |
Blumberg, A | 1 |
Esslen, E | 1 |
Bürgi, W | 1 |
Trznadel, K | 2 |
Kidawa, Z | 1 |
Walasek, L | 1 |
Lutz, W | 2 |
Bultitude, FW | 1 |
Newham, SJ | 1 |
Servo, C | 1 |
Pitkänen, E | 2 |
Sobue, G | 1 |
Mitsuma, T | 1 |
Asada, H | 1 |
Saito, A | 1 |
Inouye, M | 1 |
Mio, T | 1 |
Sumino, K | 1 |
Onishi, S | 1 |
Kawasaki, T | 1 |
Hamada, K | 1 |
Mujais, SK | 1 |
Wills, MR | 1 |
Clements, RS | 1 |
DeJesus, PV | 1 |
Winegrad, AI | 1 |
Melmed, S | 1 |
Bank, H | 1 |
Lewin, LM | 2 |
Szeinberg, A | 1 |
Lepkifker, E | 1 |
Aloia, JF | 1 |
Friis, T | 1 |
Hahnemann, S | 1 |
Weeke, E | 1 |
6 reviews available for inositol and Uremia
Article | Year |
---|---|
Recent advances in the pathogenesis and nutritional treatment of chronic uremia.
Topics: Amino Acids; Amino Acids, Essential; Arteriosclerosis; Choline; Chronic Disease; Cyclic AMP; Dietary | 1982 |
Lights and shadows on the pathogenesis of uremic polyneuropathy.
Topics: Calcium; Glucose; Guanidines; Humans; Inositol; Neurotoxins; Nutrition Disorders; Peripheral Nervous | 1982 |
Are 'middle molecules' responsible for toxic phenomena in chronic renal failure?
Topics: Anemia; Animals; Humans; Immunity, Cellular; Inositol; Kidney Failure, Chronic; Neurotoxins; Parathy | 1982 |
[Biochemical and clinical aspects of myoinositol].
Topics: Animals; Biological Transport, Active; Cell Membrane; Diabetes Mellitus; Fatty Liver; Guinea Pigs; H | 1976 |
Uremic toxins, and their effect on intermediary metabolism.
Topics: Aluminum; Animals; Creatinine; Dimethylamines; Enzyme Inhibitors; Guanidines; Humans; Inositol; Meta | 1985 |
The blessings of zinc.
Topics: Animals; Calcium; Cattle; Child; Deficiency Diseases; Diet; Female; Glycine max; Growth; Humans; Ino | 1972 |
24 other studies available for inositol and Uremia
Article | Year |
---|---|
Characterization of SNF472 pharmacokinetics and efficacy in uremic and non-uremic rats models of cardiovascular calcification.
Topics: Animals; Calcinosis; Cardiovascular Diseases; Cholecalciferol; Disease Models, Animal; Disease Progr | 2018 |
[Anti-inflammatory action of myoinositol in renal insufficiency].
Topics: Adult; Dinoprostone; Female; Humans; In Vitro Techniques; Inositol; Leukocytes, Mononuclear; Leukotr | 2006 |
Gas chromatographic--mass spectrometric analysis of polyols in urine and serum of uremic patients. Identification of new deoxyalditols and inositol isomers.
Topics: Deoxy Sugars; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Isomerism; Sugar Alcohols; Ure | 1983 |
Quantification of serum 1,5-anhydroglucitol in uremic and diabetic patients by liquid chromatography/mass spectrometry.
Topics: Adult; Aged; Aged, 80 and over; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus; Female; Fru | 1994 |
Myoinositol may be a factor in uremic immune deficiency.
Topics: Adult; CD3 Complex; CD4 Antigens; CD8 Antigens; Female; HLA-DR Antigens; Humans; In Vitro Techniques | 1997 |
In vitro methylation of arsenite by rabbit liver cytosol: effect of metal ions, metal chelating agents, methyltransferase inhibitors and uremic toxins.
Topics: Animals; Arsenites; Cresols; Cytosol; Edetic Acid; Enzyme Inhibitors; Homocysteine; Hypoxanthine; In | 1999 |
Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia.
Topics: Animals; Body Water; Brain; Chronic Disease; Hyponatremia; Inositol; Male; Mercuric Chloride; Potass | 2002 |
Plasma-myoinositol concentrations in uraemic neuropathy.
Topics: Action Potentials; Humans; Inositol; Kidney Failure, Chronic; Motor Neurons; Muscles; Neural Conduct | 1977 |
Uremic toxins.
Topics: Animals; Choline; Cyclic AMP; Humans; Inositol; Kidney; Polyamines; Renal Dialysis; Ribonucleases; U | 1978 |
Myoinositol--a uremic neurotoxin?
Topics: Adult; Blood Urea Nitrogen; Creatinine; Electroencephalography; Female; Humans; Inositol; Male; Midd | 1978 |
[A comparison of the efficiency of eliminating middle-weight molecules and myoinositol from plasma during hemoperfusion and hemodialysis in cases of chronic uremia].
Topics: Chronic Disease; Hemoperfusion; Humans; Inositol; Renal Dialysis; Toxins, Biological; Uremia | 1978 |
Identification of some abnormal metabolites in plasma from uremic subjects.
Topics: Autoanalysis; Chromatography, Gas; Chromatography, Gel; Chronic Disease; Erythritol; Glycerol; Human | 1975 |
Variation in polyol levels in cerebrospinal fluid and serum in diabetic patients.
Topics: Aged; Blood Glucose; Creatinine; Deoxyglucose; Diabetes Mellitus; Diabetic Nephropathies; Ethers, Cy | 1975 |
Myoinositol inhibits proliferation of cultured Schwann cells: evidence for neurotoxicity of myoinositol.
Topics: Animals; Cell Division; Cells, Cultured; DNA; Inositol; Nervous System Diseases; Rats; Schwann Cells | 1989 |
Profiling of organic acids and polyols in nerves of uraemic and non-uraemic patients.
Topics: Acids; Alcohols; Cauda Equina; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Peripheral Ne | 1986 |
Measurement of inositol in uremic serum by selected ion monitoring.
Topics: Adult; Benzene Derivatives; Boron Compounds; Boronic Acids; Female; Gas Chromatography-Mass Spectrom | 1988 |
Experimental studies on pathogenesis and progression of uremic neuropathy in rats. II. Is plasma myoinositol a uremic neurotoxin?
Topics: Animals; Disease Models, Animal; Inositol; Kidney Failure, Chronic; Male; Nervous System Diseases; N | 1986 |
Renal metabolic absence.
Topics: Citrates; Erythropoietin; Gluconeogenesis; Homeostasis; Humans; Inositol; Kidney; Lactates; Mevaloni | 1987 |
Raised plasma-myoinositol levels in uraemia and experimental neuropathy.
Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Chromatography, Gas; Evoked Potentials; Fasting; | 1973 |
Clinical significance of increased serum myoinositol levels.
Topics: Adolescent; Adult; Alkalies; Blood Urea Nitrogen; Chromatography, Paper; Humans; Inositol; Kidney Di | 1974 |
Gas chromatography measurement of myo-inositol in human blood, cerebrospinal fluid and seminal fluid.
Topics: Adult; Aged; Child, Preschool; Chromatography, Gas; Chromatography, Ion Exchange; Creatine Kinase; D | 1973 |
Monosaccharides and polyols in diabetes mellitus and uremia.
Topics: Adult; Aged; Blood Glucose; Chromatography, Gas; Diabetes Mellitus; Female; Fructose; Humans; Inosit | 1973 |
The serum polyol pattern and the urinary polyol excretion in diabetic and in uremic patients.
Topics: Acetobacter; Biological Assay; Borohydrides; Chromatography, Gas; Chromatography, Paper; Diabetes Me | 1972 |
Serum calcium and serum phsophorus in uraemia during administration of osdium phytate and aluminium hydroxide.
Topics: Aluminum; Bone and Bones; Calcium; Humans; Hydroxides; Hypocalcemia; Hypoparathyroidism; Inositol; K | 1968 |