inositol and Stroke
inositol has been researched along with Stroke in 8 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Stroke: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 5.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
| "Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease." | 1.62 | Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021) |
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Shah, P | 1 |
| Chavda, V | 1 |
| Patel, S | 1 |
| Bhadada, S | 1 |
| Ashraf, GM | 1 |
| Xu, B | 1 |
| Xu, J | 1 |
| Cai, N | 1 |
| Li, M | 1 |
| Liu, L | 1 |
| Qin, Y | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Villalba, H | 1 |
| Shah, K | 1 |
| Albekairi, TH | 1 |
| Sifat, AE | 1 |
| Vaidya, B | 1 |
| Abbruscato, TJ | 1 |
| Odinak, MM | 1 |
| Ianishevskiĭ, SN | 1 |
| Tsygan, NV | 1 |
| Golokhvastov, SIu | 1 |
| Vozniuk, IA | 1 |
| Trufanov, AG | 1 |
| Carlson, HL | 1 |
| Jadavji, Z | 1 |
| Mineyko, A | 1 |
| Damji, O | 1 |
| Hodge, J | 1 |
| Saunders, J | 1 |
| Hererro, M | 1 |
| Nowak, M | 1 |
| Patzelt, R | 1 |
| Mazur-Mosiewicz, A | 1 |
| MacMaster, FP | 1 |
| Kirton, A | 1 |
| Jiménez-Xarrié, E | 1 |
| Davila, M | 1 |
| Candiota, AP | 1 |
| Delgado-Mederos, R | 1 |
| Ortega-Martorell, S | 1 |
| Julià-Sapé, M | 1 |
| Arús, C | 1 |
| Martí-Fàbregas, J | 1 |
| Wang, X | 1 |
| Li, YH | 1 |
| Li, MH | 1 |
| Lu, J | 1 |
| Zhao, JG | 1 |
| Sun, XJ | 1 |
| Zhang, B | 1 |
| Ye, JL | 1 |
| Rumpel, H | 1 |
| Lim, WE | 1 |
| Chang, HM | 1 |
| Chan, LL | 1 |
| Ho, GL | 1 |
| Wong, MC | 1 |
| Tan, KP | 1 |
Trials
1 trial available for inositol and Stroke
| Article | Year |
|---|---|
[The use of succinates for the correction of metabolic disorders in the penumbra in patients with stroke].
Topics: Adult; Aged; Aged, 80 and over; Antioxidants; Brain; Glucose; Humans; Inositol; Lactates; Magnetic R | 2013 |
Other Studies
7 other studies available for inositol and Stroke
| Article | Year |
|---|---|
Promising Anti-stroke Signature of Voglibose: Investigation through In- Silico Molecular Docking and Virtual Screening in In-Vivo Animal Studies.
Topics: Animals; Cerebrovascular Disorders; Computer Simulation; Diabetes Mellitus, Experimental; Diabetes M | 2020 |
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway.
Topics: Aminopyridines; Animals; Apoptosis; Benzamides; Brain Ischemia; Cyclopropanes; Endoribonucleases; Gl | 2021 |
Potential role of myo-inositol to improve ischemic stroke outcome in diabetic mouse.
Topics: Animals; Brain; Brain Ischemia; Cell Hypoxia; Diabetes Mellitus, Experimental; Glucose; Inositol; Ma | 2018 |
Treatment of dysphasia with rTMS and language therapy after childhood stroke: Multimodal imaging of plastic change.
Topics: Adolescent; Aphasia, Broca; Brain Mapping; Broca Area; Functional Laterality; Glutamic Acid; Humans; | 2016 |
Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke.
Topics: Animals; Brain; Brain Ischemia; Creatine; Image Processing, Computer-Assisted; Inositol; Lactic Acid | 2017 |
Glutamate level detection by magnetic resonance spectroscopy in patients with post-stroke depression.
Topics: Aged; Aspartic Acid; Brain; Brain Mapping; Creatine; Depression; Female; Glutamic Acid; Humans; Inos | 2012 |
Is myo-inositol a measure of glial swelling after stroke? A magnetic resonance study.
Topics: Aged; Aged, 80 and over; Brain Edema; Creatine; Female; Humans; Inositol; Magnetic Resonance Imaging | 2003 |