Page last updated: 2024-10-19

inositol and Sterility, Male

inositol has been researched along with Sterility, Male in 12 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"Male infertility is a multifactorial disorder that affects a significant percentage of couples."2.80Myoinositol improves sperm parameters and serum reproductive hormones in patients with idiopathic infertility: a prospective double-blind randomized placebo-controlled study. ( Calogero, AE; Condorelli, RA; Gullo, G; La Vignera, S; Vaiarelli, A, 2015)
"Inositol is a component of the vitamin B complex."1.37Effects of myoinositol on sperm mitochondrial function in-vitro. ( Calogero, AE; Condorelli, RA; Di Bari, F; La Vignera, S; Unfer, V, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's1 (8.33)18.2507
2000's0 (0.00)29.6817
2010's7 (58.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Condorelli, RA4
Cannarella, R1
Crafa, A1
Barbagallo, F1
Gusmano, C1
Avola, O1
Mongioì, LM2
Basile, L1
Calogero, AE4
La Vignera, S4
Bezerra Espinola, MS1
Aragona, C1
Pallotti, F1
Cargnelutti, F1
Senofonte, G1
Carlini, T1
Faja, F1
Paoli, D1
Lombardo, F1
Vitale, SG1
Laganà, AS1
Cimino, L1
Canepa, P1
Dal Lago, A1
De Leo, C1
Gallo, M1
Rizzo, C1
Licata, E1
Anserini, P1
Rago, R1
Scaruffi, P1
Rubino, P1
Palini, S1
Chigioni, S1
Carlomagno, G1
Quagliariello, A1
De Stefani, S1
Baglioni, A1
Bulletti, C1
Gullo, G1
Vaiarelli, A1
Colone, M1
Marelli, G1
Unfer, V2
Bozzuto, G1
Molinari, A1
Stringaro, A1
Di Bari, F1
Lynch, MJ1
Masters, J1
Pryor, JP1
Lindon, JC1
Spraul, M1
Foxall, PJ1
Nicholson, JK1
Lewin, LM2
Beer, R2
Lunenfeld, B1
Glezerman, M1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Effects of Semen Incubation With ANDROSITOL®DGN on Sperm Motility and Mitochondrial Membrane Potential Before and After Oral Supplementation With Antioxidants and Myo-inositol[NCT04291495]25 participants (Actual)Interventional2018-10-23Completed
[NCT01560065]Phase 40 participants InterventionalCompleted
Effect of Myoinositol Treatment of Spermatozoa on in Vitro Fertilization Outcome: a Prospective, Randomized Sibling-oocyte Study[NCT02050672]249 participants (Actual)Interventional2013-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for inositol and Sterility, Male

ArticleYear
Myo-inositol as a male fertility molecule: speed them up!
    European review for medical and pharmacological sciences, 2017, Volume: 21, Issue:2 Suppl

    Topics: Algorithms; Asthenozoospermia; Humans; Infertility, Male; Inositol; Male

2017

Trials

2 trials available for inositol and Sterility, Male

ArticleYear
Improving fertilization rate in ICSI cycles by adding myoinositol to the semen preparation procedures: a prospective, bicentric, randomized trial on sibling oocytes.
    Journal of assisted reproduction and genetics, 2015, Volume: 32, Issue:3

    Topics: Adult; Embryo Transfer; Female; Fertilization; Fertilization in Vitro; Humans; Infertility, Male; In

2015
Myoinositol improves sperm parameters and serum reproductive hormones in patients with idiopathic infertility: a prospective double-blind randomized placebo-controlled study.
    Andrology, 2015, Volume: 3, Issue:3

    Topics: Acrosome Reaction; Adult; Double-Blind Method; Follicle Stimulating Hormone; Humans; Infertility, Ma

2015

Other Studies

9 other studies available for inositol and Sterility, Male

ArticleYear
Advances in non-hormonal pharmacotherapy for the treatment of male infertility: the role of inositols.
    Expert opinion on pharmacotherapy, 2022, Volume: 23, Issue:9

    Topics: Female; Humans; Infertility, Male; Inositol; Male; Pregnancy; Semen; Sperm Motility

2022
New perspectives on male fertility evaluation: Innovative approach for the qualitative analysis of spermatozoa.
    Andrologia, 2020, Volume: 52, Issue:1

    Topics: Adult; Chromatin; DNA Fragmentation; Fertility; Humans; Infertility, Male; Inositol; Male; Middle Ag

2020
In vitro effects of myo-inositol on normokinetic human semen samples with nonlinear motility.
    European review for medical and pharmacological sciences, 2019, Volume: 23, Issue:23

    Topics: Adult; Diagnosis, Computer-Assisted; Humans; Infertility, Male; Inositol; Male; Semen; Sperm Motilit

2019
Combined treatment with myo-inositol, alpha-lipoic acid, folic acid and vitamins significantly improves sperm parameters of sub-fertile men: a multi-centric study.
    European review for medical and pharmacological sciences, 2018, Volume: 22, Issue:20

    Topics: Adult; Female; Folic Acid; Humans; Infertility, Male; Inositol; Male; Middle Aged; Pregnancy; Reacti

2018
Inositol activity in oligoasthenoteratospermia--an in vitro study.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:10

    Topics: Humans; Infertility, Male; Inositol; Male; Mitochondria; Reactive Oxygen Species; Sperm Motility; Sp

2010
Inositol activity in oligoasthenoteratospermia--an in vitro study.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:10

    Topics: Humans; Infertility, Male; Inositol; Male; Mitochondria; Reactive Oxygen Species; Sperm Motility; Sp

2010
Inositol activity in oligoasthenoteratospermia--an in vitro study.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:10

    Topics: Humans; Infertility, Male; Inositol; Male; Mitochondria; Reactive Oxygen Species; Sperm Motility; Sp

2010
Inositol activity in oligoasthenoteratospermia--an in vitro study.
    European review for medical and pharmacological sciences, 2010, Volume: 14, Issue:10

    Topics: Humans; Infertility, Male; Inositol; Male; Mitochondria; Reactive Oxygen Species; Sperm Motility; Sp

2010
Effects of myoinositol on sperm mitochondrial function in-vitro.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:2

    Topics: Adult; Humans; Infertility, Male; Inositol; Male; Membrane Potential, Mitochondrial; Mitochondria; S

2011
Effects of myoinositol on sperm mitochondrial function in-vitro.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:2

    Topics: Adult; Humans; Infertility, Male; Inositol; Male; Membrane Potential, Mitochondrial; Mitochondria; S

2011
Effects of myoinositol on sperm mitochondrial function in-vitro.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:2

    Topics: Adult; Humans; Infertility, Male; Inositol; Male; Membrane Potential, Mitochondrial; Mitochondria; S

2011
Effects of myoinositol on sperm mitochondrial function in-vitro.
    European review for medical and pharmacological sciences, 2011, Volume: 15, Issue:2

    Topics: Adult; Humans; Infertility, Male; Inositol; Male; Membrane Potential, Mitochondrial; Mitochondria; S

2011
Ultra high field NMR spectroscopic studies on human seminal fluid, seminal vesicle and prostatic secretions.
    Journal of pharmaceutical and biomedical analysis, 1994, Volume: 12, Issue:1

    Topics: Amino Acids; Choline; Citrates; Citric Acid; Humans; Infertility, Male; Inositol; Magnetic Resonance

1994
Epididymis and seminal vesicle as sources of carnitine in human seminal fluid: the clinical significance of the carnitine concentration in human seminal fluid.
    Fertility and sterility, 1976, Volume: 27, Issue:1

    Topics: Acid Phosphatase; Carnitine; Epididymis; Epididymitis; Fructose; Humans; Infertility, Male; Inositol

1976
Electrophoretic separation of proteins on cellulose acetate: a technique for the study of prostatic and vesicular contributions in human seminal fluid.
    Fertility and sterility, 1974, Volume: 25, Issue:5

    Topics: Acid Phosphatase; Cell Count; Colorimetry; Electrophoresis; Fructose; Humans; Hydrogen-Ion Concentra

1974