inositol has been researched along with Retinoblastoma in 2 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The uptake of myo-[2-3H]inositol by mouse neuroblastoma, human Y79 retinoblastoma, human HL60, and bovine pulmonary artery endothelial cells occurs by a saturable, Na+-dependent and partially energy-dependent mechanism." | 3.67 | Myoinositol uptake by four cultured mammalian cell lines. ( Dunlap, JA; Ginsberg, BH; Yorek, MA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yorek, MA | 2 |
| Dunlap, J | 1 |
| Stefani, M | 1 |
| Davidson, E | 1 |
| Dunlap, JA | 1 |
| Ginsberg, BH | 1 |
2 other studies available for inositol and Retinoblastoma
| Article | Year |
|---|---|
Increased glucose concentration inhibits myo-inositol metabolism by two different mechanisms in cultured mammalian cells.
Topics: Animals; Cell Line; Cerebrovascular Circulation; Endothelium, Vascular; Eye Neoplasms; Glucose; Huma | 1993 |
Myoinositol uptake by four cultured mammalian cell lines.
Topics: Animals; Biological Transport, Active; Cattle; Cell Line; Endothelium; Humans; Inositol; Kinetics; L | 1986 |