Page last updated: 2024-10-19

inositol and Reperfusion Injury

inositol has been researched along with Reperfusion Injury in 8 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Reperfusion Injury: Adverse functional, metabolic, or structural changes in tissues that result from the restoration of blood flow to the tissue (REPERFUSION) following ISCHEMIA.

Research Excerpts

ExcerptRelevanceReference
"The data show that taurine protects livers from ischemia-reoxygenation."7.70Taurine attenuates cold ischemia-reoxygenation injury in rat liver. ( Häussinger, D; Wettstein, M, 2000)
"Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease."5.62Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021)
"05) in myo-inositol in the sepsis group and monoacylglycerols [(18:1) and (18:2)] in gut ischemia-reperfusion."3.88Altered Metabolic Profile of Triglyceride-Rich Lipoproteins in Gut-Lymph of Rodent Models of Sepsis and Gut Ischemia-Reperfusion Injury. ( Hickey, AJ; Hong, J; Nachkebia, S; Petzer, A; Phillips, AR; Tun, SM; Windsor, JA, 2018)
"The data show that taurine protects livers from ischemia-reoxygenation."3.70Taurine attenuates cold ischemia-reoxygenation injury in rat liver. ( Häussinger, D; Wettstein, M, 2000)
"Roflumilast (Roflu) is an FDA-approved PDE4 inhibitor for the treatment of chronic obstructive pulmonary disease."1.62Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway. ( Cai, N; Li, M; Li, X; Liu, L; Qin, Y; Wang, H; Xu, B; Xu, J, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's2 (25.00)24.3611
2020's3 (37.50)2.80

Authors

AuthorsStudies
Cai, J1
Zhang, X1
Chen, P1
Li, Y1
Liu, S1
Liu, Q1
Zhang, H1
Wu, Z1
Song, K1
Liu, J1
Shan, B1
Liu, Y1
Liang, Y1
Qu, L1
Liu, Z1
Liang, L1
Wang, Y2
Quan, S1
Tang, L1
Xu, B1
Xu, J1
Cai, N1
Li, M1
Liu, L1
Qin, Y1
Li, X1
Wang, H1
Hong, J1
Nachkebia, S1
Tun, SM1
Petzer, A1
Windsor, JA1
Hickey, AJ1
Phillips, AR1
Iwasa, M1
Kobayashi, H1
Yasuda, S1
Kawamura, I1
Sumi, S1
Yamada, Y1
Shiraki, T1
Yamaki, T1
Ushikoshi, H1
Aoyama, T1
Nishigaki, K1
Takemura, G1
Fujiwara, T1
Fujiwara, H1
Minatoguchi, S1
Wettstein, M1
Häussinger, D1
Mouton, R1
Huisamen, B1
Lochner, A1
Halát, G1
Lukácová, N1
Chavko, M1
Marsala, J1

Other Studies

8 other studies available for inositol and Reperfusion Injury

ArticleYear
The ER stress sensor inositol-requiring enzyme 1α in Kupffer cells promotes hepatic ischemia-reperfusion injury.
    The Journal of biological chemistry, 2022, Volume: 298, Issue:1

    Topics: Animals; Endoplasmic Reticulum Stress; Endoribonucleases; Hepatitis; Inflammasomes; Inflammation; In

2022
The IRE1/JNK signaling pathway regulates inflammation cytokines and production of glomerular extracellular matrix in the acute kidney injury to chronic kidney disease transition.
    Molecular biology reports, 2022, Volume: 49, Issue:8

    Topics: Acute Kidney Injury; Animals; Cytokines; Extracellular Matrix; Inflammation; Inositol; JNK Mitogen-A

2022
Roflumilast prevents ischemic stroke-induced neuronal damage by restricting GSK3β-mediated oxidative stress and IRE1α/TRAF2/JNK pathway.
    Free radical biology & medicine, 2021, 02-01, Volume: 163

    Topics: Aminopyridines; Animals; Apoptosis; Benzamides; Brain Ischemia; Cyclopropanes; Endoribonucleases; Gl

2021
Altered Metabolic Profile of Triglyceride-Rich Lipoproteins in Gut-Lymph of Rodent Models of Sepsis and Gut Ischemia-Reperfusion Injury.
    Digestive diseases and sciences, 2018, Volume: 63, Issue:12

    Topics: Animals; Biomarkers; Chromatography, Liquid; Chyle; Disease Models, Animal; Gastrointestinal Absorpt

2018
Antidiabetic drug voglibose is protective against ischemia-reperfusion injury through glucagon-like peptide 1 receptors and the phosphoinositide 3-kinase-Akt-endothelial nitric oxide synthase pathway in rabbits.
    Journal of cardiovascular pharmacology, 2010, Volume: 55, Issue:6

    Topics: alpha-Glucosidases; Animals; Arginine; Decanoic Acids; Glucagon-Like Peptide 1; Glucagon-Like Peptid

2010
Taurine attenuates cold ischemia-reoxygenation injury in rat liver.
    Transplantation, 2000, Jun-15, Volume: 69, Issue:11

    Topics: Animals; Betaine; Cryopreservation; Inositol; Ischemia; Liver; Liver Circulation; Male; Rats; Rats,

2000
Increased myocardial inositol trisphosphate levels during alpha 1-adrenergic stimulation and reperfusion of ischaemic rat heart.
    Journal of molecular and cellular cardiology, 1991, Volume: 23, Issue:7

    Topics: Adrenergic Fibers; Animals; Atropine; Coronary Disease; Heart; Inositol; Male; Myocardial Contractio

1991
Effect of severe incomplete ischaemia and postischaemic reperfusion on phospholipids and unesterified cholesterol in rabbit spinal cord.
    Physiologia Bohemoslovaca, 1990, Volume: 39, Issue:4

    Topics: Animals; Cholesterol; Inositol; Ischemia; Male; Phospholipids; Rabbits; Reperfusion Injury; Spinal C

1990