Page last updated: 2024-10-19

inositol and Psychotic Disorders

inositol has been researched along with Psychotic Disorders in 11 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Psychotic Disorders: Disorders in which there is a loss of ego boundaries or a gross impairment in reality testing with delusions or prominent hallucinations. (From DSM-IV, 1994)

Research Excerpts

ExcerptRelevanceReference
"Myo-inositol is mainly found in astroglia and its levels has been shown to be reduced in the anterior cingulate cortex (ACC) of patients with schizophrenia."5.41The trajectory of putative astroglial dysfunction in first episode schizophrenia: a longitudinal 7-Tesla MRS study. ( Jeon, P; Mackinley, M; Palaniyappan, L; Théberge, J, 2021)
"Schizophrenia is associated with significant brain abnormalities, including changes in brain metabolites as measured by proton magnetic resonance spectroscopy (MRS)."1.35A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis. ( Berger, GE; McConchie, M; McGorry, PD; Pantelis, C; Proffitt, T; Velakoulis, D; Wellard, RM; Wood, SJ, 2008)
"A case of subacute sclerosing panencephalitis in a 27-year-old man was serially evaluated with proton magnetic resonance spectroscopy."1.33Serial proton spectroscopy in a case of adult-onset subacute sclerosing panencephalitis. ( Erfurth, A; Lüdemann, P; Michael, N; Möller, HE; Schuierer, G, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's5 (45.45)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Jeon, P1
Mackinley, M1
Théberge, J1
Palaniyappan, L1
Bryant, JE1
Lahti, AC1
Briend, F1
Kraguljac, NV1
Bossong, MG1
Antoniades, M1
Azis, M1
Samson, C1
Quinn, B1
Bonoldi, I1
Modinos, G1
Perez, J1
Howes, OD1
Stone, JM1
Allen, P1
McGuire, P1
Howells, FM1
Uhlmann, A1
Temmingh, H1
Sinclair, H1
Meintjes, E1
Wilson, D1
Stein, DJ1
Plitman, E1
de la Fuente-Sandoval, C1
Reyes-Madrigal, F1
Chavez, S1
Gómez-Cruz, G1
León-Ortiz, P1
Graff-Guerrero, A1
Brandt, AS1
Unschuld, PG1
Pradhan, S1
Lim, IA1
Churchill, G1
Harris, AD1
Hua, J1
Barker, PB1
Ross, CA1
van Zijl, PC1
Edden, RA1
Margolis, RL1
Hermens, DF1
Lagopoulos, J1
Naismith, SL1
Tobias-Webb, J1
Hickie, IB1
VIDAL-TEIXIDOR, R1
GARCIA-BUNUEL, L1
GARCIA-BUNUEL, M1
Michael, N1
Erfurth, A1
Lüdemann, P1
Schuierer, G1
Möller, HE1
Wood, SJ1
Berger, GE1
Wellard, RM1
Proffitt, T1
McConchie, M1
Velakoulis, D1
McGorry, PD1
Pantelis, C1

Trials

1 trial available for inositol and Psychotic Disorders

ArticleYear
The trajectory of putative astroglial dysfunction in first episode schizophrenia: a longitudinal 7-Tesla MRS study.
    Scientific reports, 2021, 11-16, Volume: 11, Issue:1

    Topics: Adolescent; Adult; Antipsychotic Agents; Astrocytes; Female; Gyrus Cinguli; Humans; Inositol; Longit

2021

Other Studies

10 other studies available for inositol and Psychotic Disorders

ArticleYear
White Matter Neurometabolic Signatures Support the Deficit and Nondeficit Distinction in Antipsychotic-Naïve First-Episode Psychosis Patients.
    Schizophrenia bulletin, 2021, 07-08, Volume: 47, Issue:4

    Topics: Adult; Antipsychotic Agents; Case-Control Studies; Female; Glutamic Acid; Humans; Inositol; Magnetic

2021
Association of Hippocampal Glutamate Levels With Adverse Outcomes in Individuals at Clinical High Risk for Psychosis.
    JAMA psychiatry, 2019, 02-01, Volume: 76, Issue:2

    Topics: Case-Control Studies; Creatine; Cross-Sectional Studies; Female; Glutamic Acid; Hippocampus; Humans;

2019
(1)H-magnetic resonance spectroscopy ((1)H-MRS) in methamphetamine dependence and methamphetamine induced psychosis.
    Schizophrenia research, 2014, Volume: 153, Issue:1-3

    Topics: Adolescent; Adult; Aspartic Acid; Brain; Choline; Creatine; Female; Glutamine; Humans; Inositol; Mag

2014
Elevated Myo-Inositol, Choline, and Glutamate Levels in the Associative Striatum of Antipsychotic-Naive Patients With First-Episode Psychosis: A Proton Magnetic Resonance Spectroscopy Study With Implications for Glial Dysfunction.
    Schizophrenia bulletin, 2016, Volume: 42, Issue:2

    Topics: Adult; Aspartic Acid; Choline; Corpus Striatum; Glutamic Acid; Glutamine; Humans; Inositol; Neurogli

2016
Age-related changes in anterior cingulate cortex glutamate in schizophrenia: A (1)H MRS Study at 7 Tesla.
    Schizophrenia research, 2016, Volume: 172, Issue:1-3

    Topics: Adult; Aging; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Dipeptides; Female; gamma-Amin

2016
Distinct neurometabolic profiles are evident in the anterior cingulate of young people with major psychiatric disorders.
    Translational psychiatry, 2012, May-08, Volume: 2

    Topics: Adolescent; Adult; Aspartic Acid; Case Management; Combined Modality Therapy; Energy Metabolism; Fem

2012
[On the treatment of depressive states in aged persons].
    Folia clinica internacional, 1963, Volume: 13

    Topics: Dementia; Depression; Depressive Disorder; Humans; Inositol; Pentylenetetrazole; Psychotic Disorders

1963
CEREBROSPINAL FLUID LEVELS OF FREE MYOINOSITOL IN SOME NEUROLOGICAL DISORDERS.
    Neurology, 1965, Volume: 15

    Topics: Biochemical Phenomena; Biochemistry; Cerebrospinal Fluid; Child; Dementia; Diabetic Neuropathies; Ge

1965
Serial proton spectroscopy in a case of adult-onset subacute sclerosing panencephalitis.
    Psychiatry research, 2005, Aug-30, Volume: 139, Issue:3

    Topics: Adult; Aspartic Acid; Choline; Electroconvulsive Therapy; Humans; Immunologic Factors; Inositol; Int

2005
A 1H-MRS investigation of the medial temporal lobe in antipsychotic-naïve and early-treated first episode psychosis.
    Schizophrenia research, 2008, Volume: 102, Issue:1-3

    Topics: Adult; Antipsychotic Agents; Aspartic Acid; Choline; Creatine; Female; Frontal Lobe; Functional Late

2008