inositol has been researched along with Protein Aggregation, Pathological in 5 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, YH | 1 |
| Xu, K | 1 |
| Sun, Y | 1 |
| Liou, B | 1 |
| Quinn, B | 1 |
| Li, RH | 1 |
| Xue, L | 1 |
| Zhang, W | 1 |
| Setchell, KD | 1 |
| Witte, D | 1 |
| Grabowski, GA | 1 |
| Wang, P | 1 |
| Ding, K | 1 |
| Wang, H | 1 |
| Raleigh, DP | 1 |
| Rocha, EM | 1 |
| Smith, GA | 1 |
| Park, E | 1 |
| Cao, H | 1 |
| Graham, AR | 1 |
| Brown, E | 1 |
| McLean, JR | 1 |
| Hayes, MA | 1 |
| Beagan, J | 1 |
| Izen, SC | 1 |
| Perez-Torres, E | 1 |
| Hallett, PJ | 1 |
| Isacson, O | 1 |
| Brener, O | 1 |
| Dunkelmann, T | 1 |
| Gremer, L | 1 |
| van Groen, T | 1 |
| Mirecka, EA | 1 |
| Kadish, I | 1 |
| Willuweit, A | 1 |
| Kutzsche, J | 1 |
| Jürgens, D | 1 |
| Rudolph, S | 1 |
| Tusche, M | 1 |
| Bongen, P | 1 |
| Pietruszka, J | 1 |
| Oesterhelt, F | 1 |
| Langen, KJ | 1 |
| Demuth, HU | 1 |
| Janssen, A | 1 |
| Hoyer, W | 1 |
| Funke, SA | 1 |
| Nagel-Steger, L | 1 |
| Willbold, D | 1 |
1 review available for inositol and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Proteoglycans and glycosaminoglycans in misfolded proteins formation in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Clinical Trials as Topic; Glycosaminoglycans; Heparin, Low | 2014 |
4 other studies available for inositol and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Multiple pathogenic proteins implicated in neuronopathic Gaucher disease mice.
Topics: alpha-Synuclein; Amyloid beta-Protein Precursor; Animals; beta-Glucosidase; Cells, Cultured; Cerebra | 2014 |
General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers.
Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid; Diabetes Mellitus, Type 2; Inositol; Islet Amyloid | 2014 |
Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.
Topics: alpha-Synuclein; Animals; Autophagy; Axonal Transport; Cerebral Cortex; Complement Activation; Compl | 2015 |
QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Carrier Proteins; Catechin; Disease Models, Anima | 2015 |