inositol has been researched along with Pregnancy in Diabetes in 16 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present experiment was designed to determine: 1) if hyperglycemia-induced membrane injury is associated with intracellular and/or extracellular lipid disturbances; 2) if supplemental myo-inositol therapy prevents hyperglycemia-induced embryopathy; 3) if a correlation exists between dietary myo-inositol, serum and tissue levels of myo-inositol, and conceptus development; and 4) the cellular content of arachidonic acid following myo-inositol supplementation." | 7.70 | Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1998) |
| " The current investigation was undertaken to assess the use of dietary myo-inositol supplementation as a pharmacologic prophylaxis to obviate the teratogenic effects of hyperglycemia in an in vivo study." | 7.69 | Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1997) |
| " The present experiment was designed to determine: 1) if hyperglycemia-induced membrane injury is associated with intracellular and/or extracellular lipid disturbances; 2) if supplemental myo-inositol therapy prevents hyperglycemia-induced embryopathy; 3) if a correlation exists between dietary myo-inositol, serum and tissue levels of myo-inositol, and conceptus development; and 4) the cellular content of arachidonic acid following myo-inositol supplementation." | 3.70 | Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1998) |
| " The current investigation was undertaken to assess the use of dietary myo-inositol supplementation as a pharmacologic prophylaxis to obviate the teratogenic effects of hyperglycemia in an in vivo study." | 3.69 | Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats. ( Borenstein, M; Khandelwal, M; Reece, EA; Wu, YK, 1997) |
| " Dose-response studies disclosed that incremental increases in [3H]InsP1 (129-420%) are observed over a concentration range of 10-1,000 nM." | 1.29 | Glucose and scyllo-inositol impair phosphoinositide hydrolysis in the 10.5-day cultured rat conceptus: a role in dysmorphogenesis? ( Metzger, BE; Strieleman, PJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 10 (62.50) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 1 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, D | 1 |
| Reece, EA | 5 |
| Lin, X | 1 |
| Wu, Y | 1 |
| AriasVillela, N | 1 |
| Yang, P | 1 |
| Wentzel, P | 1 |
| Goto, MP | 1 |
| Goldman, AS | 1 |
| Strieleman, PJ | 1 |
| Metzger, BE | 1 |
| Eriksson, UJ | 1 |
| Khandelwal, M | 2 |
| Wu, YK | 3 |
| Borenstein, M | 2 |
| Hod, M | 3 |
| Akashi, M | 1 |
| Akazawa, S | 1 |
| Akazawa, M | 1 |
| Trocino, R | 1 |
| Hashimoto, M | 1 |
| Maeda, Y | 1 |
| Yamamoto, H | 1 |
| Kawasaki, E | 1 |
| Takino, H | 1 |
| Yokota, A | 1 |
| Shafrir, E | 1 |
| Star, S | 2 |
| Passonneau, J | 1 |
| Unterman, TG | 2 |
| Freinkel, N | 2 |
| Sinclair, SH | 1 |
| Nesler, CL | 1 |
| Schwartz, SS | 1 |
| Passonneau, JV | 1 |
| Sussman, I | 1 |
| Matschinsky, FM | 1 |
| Bourbon, JR | 1 |
| Doucet, E | 1 |
| Rieutort, M | 1 |
| Pignol, B | 1 |
| Tordet, C | 1 |
5 reviews available for inositol and Pregnancy in Diabetes
| Article | Year |
|---|---|
New development of the yolk sac theory in diabetic embryopathy: molecular mechanism and link to structural birth defects.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Female; Glucose; Humans; Hypoxia-Inducible Fact | 2016 |
Can we prevent diabetic birth defects with micronutrients?
Topics: Animals; Antioxidants; Arachidonic Acid; Congenital Abnormalities; Dietary Supplements; Female; Feta | 2009 |
Diabetic embryopathy.
Topics: Animals; Congenital Abnormalities; Female; Fetal Diseases; Humans; Inositol; Pregnancy; Pregnancy in | 1994 |
The pathogenesis of diabetes-associated congenital malformations.
Topics: Animals; Antioxidants; Arachidonic Acids; Congenital Abnormalities; Embryonic and Fetal Development; | 1996 |
Advances in the understanding of diabetic embryopathy: signal transduction.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Diabetes Mellitus, Experimental; Embryo, Mammal | 1996 |
11 other studies available for inositol and Pregnancy in Diabetes
| Article | Year |
|---|---|
Glucose and scyllo-inositol impair phosphoinositide hydrolysis in the 10.5-day cultured rat conceptus: a role in dysmorphogenesis?
Topics: Animals; Congenital Abnormalities; Embryo, Mammalian; Embryonic and Fetal Development; Female; Gesta | 1993 |
Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Embryonic and Fetal Development; Female; Hyperglycemia; In | 1997 |
Prevention of diabetic embryopathy in offspring of diabetic rats with use of a cocktail of deficient substrates and an antioxidant.
Topics: Animals; Antioxidants; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experimental; Dru | 1997 |
Dietary myo-inositol therapy in hyperglycemia-induced embryopathy.
Topics: Animals; Arachidonic Acid; Blood Glucose; Diabetes Mellitus, Experimental; Embryo, Mammalian; Embryo | 1998 |
Effects of insulin and myo-inositol on embryo growth and development during early organogenesis in streptozocin-induced diabetic rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Diet; Embryonic and Fetal Development; Female | 1991 |
Polyol pathway and fetal malformations: a search for the right mode of prevention.
Topics: Aldehyde Reductase; Animals; Congenital Abnormalities; Female; Fetal Diseases; Glucose; Inositol; Pr | 1990 |
Glucose-induced dysmorphogenesis in the cultured rat conceptus: prevention by supplementation with myo-inositol.
Topics: Animals; Congenital Abnormalities; Culture Media; Culture Techniques; Disease Models, Animal; Embryo | 1990 |
Retinopathy in the pregnant diabetic.
Topics: Adult; Blood Flow Velocity; Diabetic Angiopathies; Diabetic Retinopathy; Enzymes; Female; Fluorescei | 1985 |
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Congenital Abnormalities; Culture Techniques; Female; Fe | 1986 |
Diabetes affects sorbitol and myo-inositol levels of neuroectodermal tissue during embryogenesis in rat.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Body Weight; Creatine; Diabetes Mellitus, Ex | 1988 |
Role of myo-inositol in impairment of fetal lung phosphatidylglycerol biosynthesis in the diabetic pregnancy: physiological consequences of a phosphatidylglycerol-deficient surfactant in the newborn rat.
Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Female; Glycerol; | 1986 |