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inositol and Pheochromocytoma

inositol has been researched along with Pheochromocytoma in 5 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"We have used rat PC12 pheochromocytoma cells, a clonal cell line closely related to sympathetic neurons, to investigate reports that the bradykinin receptor expressed in the peripheral nervous system is distinct from the well-characterized B2 bradykinin receptor of smooth muscle."7.69Identification of a B2 bradykinin receptor expressed by PC12 pheochromocytoma cells. ( Gerald, C; Hogan, PG; Nardone, J; Rimawi, L; Song, L, 1994)
"We have used rat PC12 pheochromocytoma cells, a clonal cell line closely related to sympathetic neurons, to investigate reports that the bradykinin receptor expressed in the peripheral nervous system is distinct from the well-characterized B2 bradykinin receptor of smooth muscle."3.69Identification of a B2 bradykinin receptor expressed by PC12 pheochromocytoma cells. ( Gerald, C; Hogan, PG; Nardone, J; Rimawi, L; Song, L, 1994)
"Both carbachol and bradykinin increased diacylglycerol formation in PC12 pheochromocytoma cells."3.68Carbachol and bradykinin increase the production of diacylglycerol from sources other than inositol-containing phospholipids in PC12 cells. ( Horwitz, J, 1990)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's3 (60.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lakshmanan, J1
Tarris, R1
Lee, MI1
Fisher, DA1
Nardone, J1
Gerald, C1
Rimawi, L1
Song, L1
Hogan, PG1
Weiss, C1
Atlas, D1
Horwitz, J1
Volonté, C1
Parries, GS1
Racker, E1

Other Studies

5 other studies available for inositol and Pheochromocytoma

ArticleYear
Nerve growth factor rescues clonal PC-12 pheochromocytoma cells from "inositol-less death".
    Biochemical and biophysical research communications, 1982, Mar-15, Volume: 105, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Biological Assay; Blood Pressure; Cell Line; Cell Survival; Cultur

1982
Identification of a B2 bradykinin receptor expressed by PC12 pheochromocytoma cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, May-10, Volume: 91, Issue:10

    Topics: Adrenal Gland Neoplasms; Animals; Base Sequence; Binding, Competitive; Bradykinin; Cell Line; Chloro

1994
The bradykinin receptor--a putative receptor-operated channel in PC12 cells: studies of neurotransmitter release and inositol phosphate accumulation.
    Brain research, 1991, Mar-08, Volume: 543, Issue:1

    Topics: Adrenal Gland Neoplasms; Animals; Bradykinin; Calcium; Calcium Channel Blockers; Cell Line; Cyclic A

1991
Carbachol and bradykinin increase the production of diacylglycerol from sources other than inositol-containing phospholipids in PC12 cells.
    Journal of neurochemistry, 1990, Volume: 54, Issue:3

    Topics: Bradykinin; Calcium; Carbachol; Diglycerides; Glycerides; Inositol; Inositol Phosphates; N-Methylsco

1990
Stimulation of inositol incorporation into lipids of PC12 cells by nerve growth factor and bradykinin.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Bradykinin; Calcimycin; Chlorides; Inositol; Inositol Phosphates;

1988