Page last updated: 2024-10-19

inositol and Peripheral Nerve Diseases

inositol has been researched along with Peripheral Nerve Diseases in 16 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal."9.22Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. ( Bräuninger, S; Chung, HY; Geis, C; Haas, J; Jarius, S; Komorowski, L; Roth, C; Wildemann, B, 2022)
"We tested the ability of lithium (Li(+)) to block heat hyperalgesia, cold allodynia, mechanical allodynia and mechanical hyperalgesia in rats experimentally subjected to painful peripheral neuropathy."7.70Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Shibata, M; Shimizu, T; Wakisaka, S; Yoshiya, I, 2000)
"In 2014, we first described novel autoantibodies to the inositol 1,4,5-trisphosphate receptor type 1 (ITPR1-IgG/anti-Sj) in patients with autoimmune cerebellar ataxia (ACA) in this journal."5.22Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature. ( Bräuninger, S; Chung, HY; Geis, C; Haas, J; Jarius, S; Komorowski, L; Roth, C; Wildemann, B, 2022)
"We tested the ability of lithium (Li(+)) to block heat hyperalgesia, cold allodynia, mechanical allodynia and mechanical hyperalgesia in rats experimentally subjected to painful peripheral neuropathy."3.70Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy. ( Inoue, T; Mashimo, T; Shibata, M; Shimizu, T; Wakisaka, S; Yoshiya, I, 2000)
"In a series of patients with chronic renal failure managed conservatively, the rise in the plasma-myo-inositol (myoinositol) concentration has been found to be related to depression of sural-nerve conduction velocity."1.26Plasma-myoinositol concentrations in uraemic neuropathy. ( Reznek, RH; Salway, JG; Thomas, PK, 1977)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19909 (56.25)18.7374
1990's4 (25.00)18.2507
2000's2 (12.50)29.6817
2010's0 (0.00)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Jarius, S1
Bräuninger, S1
Chung, HY1
Geis, C1
Haas, J1
Komorowski, L1
Wildemann, B1
Roth, C1
Savazzi, GM1
Buzio, C1
Migone, L1
Navarro, J1
Contreras, P1
Touraine, JL1
Freyria, AM1
Later, R1
Traeger, J1
Yorek, MA1
Wiese, TJ1
Davidson, EP1
Dunlap, JA1
Conner, CE1
Terril-Robb, LA1
Clemons, DJ1
Besch-Williford, C1
O'Brien, DP1
O'Dell, BL1
Shimizu, T1
Shibata, M1
Wakisaka, S1
Inoue, T1
Mashimo, T1
Yoshiya, I1
Tabata, H1
Ikegami, H1
Kariya, K1
Reznek, RH1
Salway, JG1
Thomas, PK1
Anderson, JW1
Karjalainen, T1
Smith, WJ1
Diemel, LT1
Leach, RM1
Tomlinson, DR1
Greene, DA1
Lattimer, SA1
Niwa, T1
Asada, H1
Maeda, K1
Yamada, K1
Ohki, T1
Saito, A1
Kuzuhara, K1
Kaniu, H1
Tsuji, H1
Furukawa, K1
Miura, M1
Hara, S1
Suzuki, Y1
Nihei, H1
Akagi, K1
Uchigata, M1
Nishimura, C1
Lou, MF1
Kinoshita, JH1
Clements, RS1
DeJesus, PV1
Winegrad, AI1

Reviews

5 reviews available for inositol and Peripheral Nerve Diseases

ArticleYear
Inositol 1,4,5-trisphosphate receptor type 1 autoantibody (ITPR1-IgG/anti-Sj)-associated autoimmune cerebellar ataxia, encephalitis and peripheral neuropathy: review of the literature.
    Journal of neuroinflammation, 2022, Jul-30, Volume: 19, Issue:1

    Topics: Autoantibodies; Carrier Proteins; Cerebellar Ataxia; Encephalitis; Female; Humans; Immunoglobulin G;

2022
Lights and shadows on the pathogenesis of uremic polyneuropathy.
    Clinical nephrology, 1982, Volume: 18, Issue:5

    Topics: Calcium; Glucose; Guanidines; Humans; Inositol; Neurotoxins; Nutrition Disorders; Peripheral Nervous

1982
Are 'middle molecules' responsible for toxic phenomena in chronic renal failure?
    Nephron, 1982, Volume: 32, Issue:4

    Topics: Anemia; Animals; Humans; Immunity, Cellular; Inositol; Kidney Failure, Chronic; Neurotoxins; Parathy

1982
Metabolic abnormalities contributing to diabetic complications. II. Peripheral nerves.
    The American journal of clinical nutrition, 1976, Volume: 29, Issue:4

    Topics: Animals; Axons; Cricetinae; Diabetes Mellitus; Diabetic Neuropathies; Disease Models, Animal; Glucos

1976
[The pathogenesis of polyneuropathies].
    Duodecim; laaketieteellinen aikakauskirja, 1991, Volume: 107, Issue:8

    Topics: Diabetic Neuropathies; Female; Glucose; Humans; Inositol; Male; Peripheral Nervous System Diseases;

1991

Other Studies

11 other studies available for inositol and Peripheral Nerve Diseases

ArticleYear
Reduced Na+/K+ adenosine triphosphatase activity and motor nerve conduction velocity in L-fucose-fed rats is reversible after dietary normalization.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:2

    Topics: Animals; Dietary Carbohydrates; Fucose; Inositol; Male; Motor Neurons; Neural Conduction; Peripheral

1996
Morphophysiologic characterization of peripheral neuropathy in zinc-deficient guinea pigs.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1996, Volume: 213, Issue:1

    Topics: Animals; Blood Glucose; Body Weight; Brachial Plexus; Carbohydrates; Evoked Potentials, Somatosensor

1996
Intrathecal lithium reduces neuropathic pain responses in a rat model of peripheral neuropathy.
    Pain, 2000, Volume: 85, Issue:1-2

    Topics: Animals; Chronic Disease; Cold Temperature; Drug Interactions; Hot Temperature; Hyperalgesia; Inject

2000
Spontaneous age-related peripheral neuropathy in B6C3F1 mice.
    The Journal of toxicological sciences, 2000, Volume: 25, Issue:2

    Topics: Aging; Animals; Axons; Blood Glucose; Body Temperature; Cell Division; Female; Glycated Hemoglobin;

2000
Plasma-myoinositol concentrations in uraemic neuropathy.
    Lancet (London, England), 1977, Mar-26, Volume: 1, Issue:8013

    Topics: Action Potentials; Humans; Inositol; Kidney Failure, Chronic; Motor Neurons; Muscles; Neural Conduct

1977
Central hypoxaemia in rats provokes neurological defects similar to those seen in experimental diabetes mellitus: evidence for a partial role of endoneurial hypoxia in diabetic neuropathy.
    Neuroscience, 1991, Volume: 45, Issue:2

    Topics: Animals; Diabetic Neuropathies; Glucose; Hypoxia; Inositol; Male; Nerve Tissue Proteins; Neural Cond

1991
Recent advances in the therapy of diabetic peripheral neuropathy by means of an aldose reductase inhibitor.
    The American journal of medicine, 1985, Nov-15, Volume: 79, Issue:5A

    Topics: Aldehyde Reductase; Animals; Biological Transport; Diabetic Neuropathies; Humans; Imidazoles; Imidaz

1985
Profiling of organic acids and polyols in nerves of uraemic and non-uraemic patients.
    Journal of chromatography, 1986, Apr-25, Volume: 377

    Topics: Acids; Alcohols; Cauda Equina; Gas Chromatography-Mass Spectrometry; Humans; Inositol; Peripheral Ne

1986
[Relationship between serum myo-inositol and peripheral neuropathy in patients with chronic renal failure].
    Nihon Jinzo Gakkai shi, 1986, Volume: 28, Issue:6

    Topics: Creatinine; Humans; Inositol; Kidney Failure, Chronic; Neural Conduction; Peripheral Nervous System

1986
Depletion of myo-inositol and amino acids in galactosemic neuropathy.
    Journal of neurochemistry, 1987, Volume: 49, Issue:1

    Topics: Amino Acids; Animals; Galactose; Inositol; Male; Peripheral Nervous System Diseases; Rats; Rats, Inb

1987
Raised plasma-myoinositol levels in uraemia and experimental neuropathy.
    Lancet (London, England), 1973, May-26, Volume: 1, Issue:7813

    Topics: Administration, Oral; Animals; Blood Urea Nitrogen; Chromatography, Gas; Evoked Potentials; Fasting;

1973